scholarly journals Melanin-Like Nanomedicine in Photothermal Therapy Applications

2021 ◽  
Vol 22 (1) ◽  
pp. 399
Author(s):  
Yale Yue ◽  
Xiao Zhao

Photothermal therapy (PTT) mediated by nanomaterial has become an attractive tumor treatment method due to its obvious advantages. Among various nanomaterials, melanin-like nanoparticles with nature biocompatibility and photothermal conversion properties have attracted more and more attention. Melanin is a natural biological macromolecule widely distributed in the body and displays many fascinating physicochemical properties such as excellent biocompatibility and prominent photothermal conversion ability. Due to the similar properties, Melanin-like nanoparticles have been extensively studied and become promising candidates for clinical application. In this review, we give a comprehensive introduction to the recent advancements of melanin-like nanoparticles in the field of photothermal therapy in the past decade. In this review, the synthesis pathway, internal mechanism and basic physical and chemical properties of melanin-like nanomaterials are systematically classified and evaluated. It also summarizes the application of melanin-like nanoparticles in bioimaging and tumor photothermal therapy (PTT)in detail and discussed the challenges they faced in clinical translation rationally. Overall, melanin-like nanoparticles still have significant room for development in the field of biomedicine and are expected to applied in clinical PTT in the future.

Author(s):  
O.G. Drugova ◽  
◽  
A.A. Fedoruk ◽  
T.N. Shtin

Abstract. Due to the predominance of PM1 particles in the air samples, the following metals were found in the aerosol: copper, zinc, silicon, iron, lead, sulfur, arsenic, aluminum, antimony, tin, magnesium, cadmium and several other metals. The content of sulfates was significantly noted. These physical and chemical properties show a considerable toxic potential of industrial aerosol. The MPC of lead, sulfur and silicon dioxides, as well as nitrogen oxides and formaldehyde were detected in the working air. Meanwhile, copper, zinc, and iron did not exceed their MPC. Moreover, an underestimation of the aerosol was observed within the framework of industrial control. It has been found that the aerosol components may have an irritating, reprotoxic, allergenic, and carcinogenic effect on the body. Further consideration of the dispersed and chemical composition of the aerosol is required to determine the concentration of identified substances in the working air and the limiting components determining its biological effect.


2021 ◽  
Vol 9 (38) ◽  
pp. 8109-8120
Author(s):  
Hao Liu ◽  
Haolin Chen ◽  
Xiaoying Liu ◽  
Luoqi Mo ◽  
Chao Chen ◽  
...  

1T-phase niobium telluride (NbTe2) nanosheets are becoming increasingly important in emerging fields, such as spintronics, sensors and magneto-optoelectronics, due to their excellent physical and chemical properties.


Nanoscale ◽  
2020 ◽  
Vol 12 (43) ◽  
pp. 21971-21987
Author(s):  
Qicheng Zhang ◽  
Wenchao Peng ◽  
Yang Li ◽  
Fengbao Zhang ◽  
Xiaobin Fan

Over the past several decades, nanomaterials have been extensively studied owing to having a series of unique physical and chemical properties that exceed those of conventional bulk materials.


2018 ◽  
Vol 9 (15) ◽  
pp. 3623-3637 ◽  
Author(s):  
Xiubing Huang ◽  
Guixia Zhao ◽  
Ge Wang ◽  
John T. S. Irvine

Perovskite-type metal oxides have been widely investigated and applied in various fields in the past several decades due to their extraordinary variability of compositions and structures with targeted physical and chemical properties (e.g., redox behaviour, oxygen mobility, electronic and ionic conductivity).


Nanomedicine ◽  
2019 ◽  
Vol 14 (20) ◽  
pp. 2763-2775 ◽  
Author(s):  
Fatih Zor ◽  
Fatma Nurefsan Selek ◽  
Giuseppe Orlando ◽  
David F Williams

Biocompatibility is a very common word that is used within biomaterial science and used for description of the interactions between the foreign material and the body. However, the meaning of biocompatibility as well as the mechanisms that collectively constitutes is still unclear. With the advance of nanotechnology, new concerns have been observed related to biocompatibility of these biomaterials. Due to their small size and variability of their physical and chemical properties, nanoparticles’ (NP) distribution within the body and interactions with the target cells and tissues are highly variable. Here, we tried to provide an overview about NPs, the concept of biocompatibility and biocompatibility-related issues in nanomedicine and several different NPs.


2020 ◽  
Vol 16 (6) ◽  
pp. 739-762
Author(s):  
Minyu Zhou ◽  
Yunfei Zhou ◽  
Yixin Cheng ◽  
Yanqi Wu ◽  
Jun Yang ◽  
...  

Photothermal therapy (PTT) is a minimally invasive tumor treatment method in which photothermal conversion agents (PTAs) can be enriched in tumor tissue by external light stimulation to convert photon energy into thermal energy to induce the temperature of tumor tissue higher than normal physiological, and can effectively kill tumor cells and tissues while avoiding damage to healthy tissue. As a well-known biocompatible nanomaterial, gold-based nanomaterials have high photothermal conversion efficiency and cross section, which can be used in tumor targeting therapy treatment as a potential photothermal conversion agent. Combining PTT and chemotherapy can be achieved by loading a chemotherapeutic drug modified on the surface of a gold nanomaterials. Therefore, this paper first reviews the preparation and surface functionalization of Au-based nanomaterials, such as Au nanorods, Au nanostars, Au nanoshells, and so on. Second, we have also introduced the application of Au-based nanomaterials in PTT, chemotherapy, and combination therapy. Finally, the limitations and challenges of Au-based photothermal conversion agents are summarized and the development prospects in this field are prospected.


2012 ◽  
Vol 479-481 ◽  
pp. 2028-2032
Author(s):  
Zhi Yong Pan ◽  
Sheng Yin Song ◽  
Wen Hong Liu ◽  
Xin Li Han ◽  
Jun Han ◽  
...  

Dropout may be happen to round thread connection by main reasons of design and process of product, material’s property, make-up torque or make-up position, field operation problems etc.. Casing’s property has get a high improvement with the development over the past decade in China. But the number of connection dropout accident didn’t declined obviously. These lead to great economy loss and safety hazard had taken place. Research on a round thread connection pullout case was carried out combining relative theorys with tests. Macroscopic analysis and dimension measurement and material’s physical and chemical properties were checked for casings and couplings. Thread inspection and full-scale tests were done for casing simples that are same lot with dropout. Comprehensive analysis was carried out on these results. The results showed that dropout failure was ascribe to two main causes. One is make-up location cann’t reach standard location at field end, and the other is incorrect holding position on coupling in the course of making up.


Nanoscale ◽  
2021 ◽  
Author(s):  
Bowen Li ◽  
Jiazhong Geng ◽  
Haoqiang Ai ◽  
youchao Kong ◽  
Haoyun Bai ◽  
...  

Two-dimensional (2D) materials have attracted increasing interest in the past decades due to their unique physical and chemical properties for diverse applications. In this work, we present a first-principle design...


2011 ◽  
Vol 35 (4) ◽  
pp. 1069-1080 ◽  
Author(s):  
Fábio Henrique Alves Bispo ◽  
Alexandre Christofaro Silva ◽  
Pablo Vidal Torrado

In the upper Jequitinhonha valley, state of Minas Gerais, Brazi, there are large plane areas known as "chapadas", which are separated by areas dissected by tributaries of the Jequitinhonha and Araçuaí rivers. These dissected areas have a surface drainage system with tree, shrub, and grass vegetation, more commonly known as "veredas", i.e., palm swamps. The main purpose of this study was to characterize soil physical, chemical and morphological properties of a representative toposequence in the watershed of the Vereda Lagoa do Leandro, a swamp near Minas Novas, MG, on "chapadas", the highlands of the Alto Jequitinhonha region Different soil types are observed in the landscape: at the top - Typic Haplustox (LVA), in the middle slope - Xanthic Haplustox (LA), at the footslope - Xanthic Haplustox, gray color, here called "Gray Haplustox" ("LAC") and, at the bottom of the palm swamp - Typic Albaquult (GXbd). These soils were first morphologically described; samples of disturbed and undisturbed soils were collected from all horizons and subhorizons, to evaluate their essential physical and chemical properties, by means of standard determination of Fe, Al, Mn, Ti and Si oxides after sulfuric extraction. The contents of Fe, Al and Mn, extracted with dithionite-citrate-bicarbonate and oxalate treatments, were also determined. In the well-drained soils of the slope positions, the typical morphological, physical and chemical properties of Oxisols were found. The GXbd sample, from the bottom of the palm swamp, is grayish and has high texture gradient (B/A) and massive structure. The reduction of the proportion of crystalline iron compounds and the low crystallinity along the slope confirmed the loss of iron during pedogenesis, which is reflected in the current soil color. The Si and Al contents were lowest in the "LAC" soil. There was a decrease of the Fe2O3/TiO2 ratio downhill, indicating progressive drainage restriction along the toposequence. The genesis and all physical and chemical properties of the soils at the footslope and the bottom of the palm swamp of the "chapadas" of the Alto Jequitinhonha region are strongly influenced by the occurrence of ground water on the surface or near the surface all year long, at present and/or in the past. Total concentrations of iron oxides, Fe d and Fe o in soils of the toposequence studied are related to the past and/or present soil colors and drainage conditions.


KALPATARU ◽  
2015 ◽  
Vol 24 (1) ◽  
pp. 47
Author(s):  
M. Fadlan S.

Abstrak. Tembikar merupakan salah satu sisa benda budaya yang paling sering ditemukan dalam penelitian arkeologi, yang terbuat dari tanah liat yang dibakar. Analisis teknologi laboratoris tembikar dari situs-situs di DAS Bengawan Solo Bojonegoro, bertujuan untuk memperoleh hasil yang akurat tentang sifat fisik dan sifat kimia. Melalui kajian analisis teknologi laboratoris dapat digambarkan kualitas tembikar yang dibuat oleh para pengrajin pada masa lampau. Berdasarkan hasil analisis teknologi laboratoris tembikar dari situs-situs DAS Bengawan Solo, Bojonegoro mempunyai kualitas sedang hingga kualitas baik. Tembikar-tembikar tersebut termasuk dalam kategori peralatan sehari-hari yang berfungsi untuk menampung air, mengolah makanan dan untuk penyajian makanan serta minuman. Tingkat pembakarannya mencapai 600°-800° Celcius, dan warna tembikar didominasi warna gelap (dark colors) dibanding dengan warna terang (light colors). Adanya perbedaan prosentase dari setiap unsur kimia pada tembikar tersebut, tidak terlepas dari daya tahan mineral terhadap pelapukan.Abstract. Pottery, which is made of fired clay, is the most frequently found cultural remains during archaeological researches. Technological Laboratory Analysis on pottery from sites along the Bengawan Solo (Solo River) in Bojonegoro aims at obtaining accurate results about the nature of the physical and chemical properties. Through the technological laboratory analysis can be described the quality of pottery made by craftsmen in the past. Based on the results of the analysis, pottery from the sites along the Bengawan Solo, Bojonegoro Regency, have moderate up to good qualities. The pottery belongs to a category of daily equipment that serves to store water, cook food and to serve food and drink. The rate of heat during firing was up to 600°-800° Celsius, and the color of pottery is predominantly dark colors (black colors) with only a few light colors (bright colors). The difference in the percentage of each chemical element in the pottery is due to the durability of the minerals to weathering.


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