scholarly journals Effects of Omega 3 Fatty Acids on Main Dimensions of Psychopathology

2020 ◽  
Vol 21 (17) ◽  
pp. 6042 ◽  
Author(s):  
Paola Bozzatello ◽  
Maria Laura De Rosa ◽  
Paola Rocca ◽  
Silvio Bellino
Keyword(s):  
Fatty Acids ◽  
Phospholipid Composition ◽  
Autism Spectrum ◽  
Psychotic Symptoms ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Symptom Dimensions ◽  
Hyperactivity Disorder ◽  
Affective Symptoms ◽  
Spectrum Disorders

The usefulness of polyunsaturated fatty acids on inflammatory, cardiovascular, and the nervous system was studied in the last decades, but the mechanisms underlying their benefic properties are still partially unknown. These agents seem to express their action on the membrane phospholipid composition and permeability and modulation of second messenger cascades. In psychiatry, the efficacy and tolerability of omega-3 fatty acids were investigated in several psychiatric disorders, including major depression, bipolar disorder, personality disorders, high-risk conditions to develop psychosis, attention-deficit hyperactivity disorder, and autism spectrum disorders. Initial findings in this field are promising, and some relevant questions need to be addressed. In particular, the effects of these agents on the main symptom dimensions have to be investigated in a trans-diagnostic perspective. The present systematic review is aimed to examine the available data on the efficacy of omega-3 fatty acids on domains of psychotic symptoms, affective symptoms, impulsivity, and aggressiveness, and harmful behaviors, and suicide risk.

scholarly journals Omega-3 fatty acids are related to abnormal emotion processing in adolescent boys with attention deficit hyperactivity disorder

2013 ◽  
Vol 88 (6) ◽  
pp. 419-429 ◽  
Author(s):  
Rachel V. Gow ◽  
Alexander Sumich ◽  
Frederic Vallee-Tourangeau ◽  
Michael Angus Crawford ◽  
Kebreab Ghebremeskel ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Emotion Processing ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Adolescent Boys ◽  
Hyperactivity Disorder

scholarly journals May the best friend be an enemy if not recognized early: possible role of omega-3 against cardiovascular abnormalities due antipsychotics in the treatment of autism

2009 ◽  
Vol 67 (3b) ◽  
pp. 922-926 ◽  
Author(s):  
Roberta M. Cysneiros ◽  
Vera C. Terra ◽  
Hélio R. Machado ◽  
Ricardo M. Arida ◽  
José Salomão Schwartzman ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Protective Role ◽  
Autism Spectrum ◽  
Antipsychotic Treatment ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Case Control Studies ◽  
Qt Interval Prolongation

Autism spectrum disorders (ASD) are neurodevelopment disorders that cause severe and pervasive impairment in socialization, communication, and behavior. Although the availability of antipsychotic treatment in ASD has expanded, we will be very careful with side effects of these pharmacological agents. Following this reasoning, emerging data indicate that some antipsychotics may be associated with cardiovascular adverse events (e.g., QT interval prolongation), suggesting that this could be correlated to sudden death. Quite interesting, substantial evidence from epidemiological and case-control studies indicates that omega-3 reduces the risk of cardiovascular mortality, particularly sudden cardiac death. In accordance to the above mentioned findings, as omega-3 fatty acids per se have a direct cardiovascular protective role, our paper hypothesized that omega-3 fatty acids supplementation in ASD patients treated with atypical antipsychotic drugs may reduce cardiac arrhythmias and hence sudden cardiac death.

Sign in / Sign up

Export Citation Format

Share Document