scholarly journals Screen for Potential Candidate Alternatives of Sargentodoxa cuneata from Its Six Adulterants Based on Their Phenolic Compositions and Antioxidant Activities

2019 ◽  
Vol 20 (21) ◽  
pp. 5427 ◽  
Author(s):  
Lingguang Yang ◽  
Peipei Yin ◽  
Xinxin Cao ◽  
Yujun Liu

Daxueteng, the liana stem of Sargentodoxa cuneata, is a widely used Traditional Chinese Medicine facing the overflow of its commercial adulterants. A method for discriminating adulterants and screening potential candidate alternatives of S. cuneata was thus established. Total phenols and flavonoids of S. cuneata and its six adulterants and their abilities to scavenge DPPH• and ABTS•+, to absorb peroxyl radicals (ORAC), and to inhibit AAPH-induced supercoiled plasmid DNA strand scission were comprehensively assessed. Polygonum cuspidatum and Bauhinia championii, two of the six adulterants of S. cuneate, shared considerably higher antioxidant activities as well as phenolic contents and, therefore, were considered as potential candidate alternatives. Phenolic compositions of the two potential candidate alternatives and S. cuneata itself were further determined by UPLC-QTOF-MS/MS. Totally 38 phenolics, including four hydroxybenzoic acids, two tyrosols, two caffeoylquinic acids, seven flavanol or its oligomers, two lignans, three hydroxycinnamic acids, six stilbenes, seven anthraquinones, and five flavanones were determined from three species. Furthermore, contents of different phenolic categories were semi-quantified and the major antioxidant contributors of S. cuneata and the two potential candidate alternatives were subsequently determined. It is concluded that tyrosols and caffeoylquinic acids were unique categories making great antioxidant contributions in S. cuneata and thus were considered as effective biomarkers in distinguishing its potential candidate alternatives.

2019 ◽  
Vol 14 (2) ◽  
Author(s):  
Himani Singh ◽  
Madhuri Kaushish Lily ◽  
Koushalya Dangwal

Dendrobenthamidia capitata (Wall.) Hutch. fruit (Bhamora) is a popular yet underexplored wild edible fruit of Uttarakhand state of Indian Himalayan region. Therefore, the present study was aimed to analyze D. capitata fruit for its phenolic contents, antioxidant, anti-elastase, anti-collagenase, and anti-tyrosinase activities using in- vitro assays. Phenolics and flavonoids were extracted using 80 % aqueous acetone and acid acetone as solvents. Our analysis revealed high values of total phenolic contents of 4.38±0.08 mg gallic acid equivalents (GAE). g-1 fruit weight and total flavonoid contents of 7.47±0.66 mg catechin equivalents (CE). g-1 fruit weight in the acid acetone fruit extracts of D. capitata. D. capitata fruit extracts demonstrated remarkable antioxidant activities (ABTS+, 1,1- diphenyl-2-picrylhydrazyl, superoxide anion, linoleate peroxyl radicals scavenging, and ferric reducing activities) and notable anti-elastase, anti-collagenase, and anti-tyrosinase activities. High resolution liquid chromatography– mass spectroscopy analysis revealed presence of six phenolic compounds, namely, dihydrorobinetin, dhydromyricetin, retusin dimethyl ether, rotenone, bergenin (C-glycoside of 4-O-methyl gallic acid) and peucenin in fruit extracts. This study recommends utilization of D.capitata fruit as functional food with prospective pharmaceutical, nutraceutical, and cosmeceutical properties.


2017 ◽  
Vol 68 (7) ◽  
pp. 1429-1434 ◽  
Author(s):  
Gabriela Stanciu ◽  
Nicoleta Cristache ◽  
Simona Lupsor ◽  
Simona Dobrinas

The total phenols contents and antioxidant activities of alcoholic extractive solutions of Ocimum basilicum (basil), Thymus vulgaris (thyme), Mentha piperita (mint), Rosmarinus officinalis (rosemary), Sativa officinalis (sage), Artemisia dracunculus (tarragon) and Coriandrum sativum (coriander) were examined using Folin-Ciocalteu method and ACL method, respectively. Extractive alcoholic solutions of above mentioned seven spices were analyzed during a period of five months in order to determine the optimal extraction time when the polyphenolic content was at maximum. The highest total phenolic contents were registered for rosemary (608.37 mg GAE/100 g d.w.), sage (530.66 mg GAE/100g d.w.) and mint (511.87 mg GAE/100g d.w.) In general the optimal extraction time of the total phenolic content was reached after 3 months of maceration, except thyme, tarragon (after two months) and coriander (after one month). The antioxidant capacity ranged between 1410.1 nmols Trolox/g d.w. for rosemary and 4.2560 nmols Trolox/g d.w. for tarragon.


2019 ◽  
Vol 14 (2) ◽  
Author(s):  
Himani Singh ◽  
Madhuri Kaushish Lily ◽  
Koushalya Dangwal

Dendrobenthamidia capitata (Wall.) Hutch. fruit (Bhamora) is a popular yet underexplored wild edible fruit of Uttarakhand state of Indian Himalayan region. Therefore, the present study was aimed to analyze D. capitata fruit for its phenolic contents, antioxidant, anti-elastase, anti-collagenase, and anti-tyrosinase activities using in- vitro assays. Phenolics and flavonoids were extracted using 80 % aqueous acetone and acid acetone as solvents. Our analysis revealed high values of total phenolic contents of 4.38±0.08 mg gallic acid equivalents (GAE). g-1 fruit weight and total flavonoid contents of 7.47±0.66 mg catechin equivalents (CE). g-1 fruit weight in the acid acetone fruit extracts of D. capitata. D. capitata fruit extracts demonstrated remarkable antioxidant activities (ABTS+, 1,1- diphenyl-2-picrylhydrazyl, superoxide anion, linoleate peroxyl radicals scavenging, and ferric reducing activities) and notable anti-elastase, anti-collagenase, and anti-tyrosinase activities. High resolution liquid chromatography– mass spectroscopy analysis revealed presence of six phenolic compounds, namely, dihydrorobinetin, dhydromyricetin, retusin dimethyl ether, rotenone, bergenin (C-glycoside of 4-O-methyl gallic acid) and peucenin in fruit extracts. This study recommends utilization of D.capitata fruit as functional food with prospective pharmaceutical, nutraceutical, and cosmeceutical properties.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
I Orhan ◽  
M Kartal ◽  
FS Şenol ◽  
M Abou-Asaker ◽  
B Şener

2008 ◽  
Vol 7 (1) ◽  
Author(s):  
Bimo Budi Santoso

<strong><em>Flavanoid, steroid, and terpenoid contents of 20 Manokwari medicinal plants were analyzed.  The antioxidant activity, total phenolic contents and antitumor activity of 20 Manokwari medicinal plants were also evaluated. The result shows that 83% positif to flavanoid test, 59% positif to terpenoid test and only 25% positif steroid. Antioxidant activity and total phenolic contents evaluated using Ferric Thiocianate (FTC) and Folin-Ciocalteu methods respectively. Antioxidant activity and total phenolic contents of medicinal plants were extracted by the traditional method, boiling in water and also in 80% methanol. Twenty plants evaluated in both exstracts have significantly varies of antioxidant activities and phenolic contents,  A significant and linier correlation coefficient between the antioxidant activity and the total phenolic content was found in both aqueous (R<sup>2</sup>= 0,77) and methanol (R<sup>2</sup> = 0,85). Antitumor activity was tested using cell maurine P-388 and only 2 of medicinal plants are active to inhibit cell maurine P-388. Comparing extraction efficiency of the two methods, the methanol extracted phenolic compounds more efficiently, and antioxidant activity of the extract was higher.</em></strong>


2021 ◽  
Author(s):  
Paulina Anita Strugała ◽  
Anna Urbaniak ◽  
Patryk Kuryś ◽  
Aleksandra Włoch ◽  
Teresa Kral ◽  
...  

The aim of study was to broadly determine the biological activities of purple potato ethanolic extract of the Blue Congo variety (BCE). The antioxidative activity of BCE was determined in...


Antioxidants ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 215 ◽  
Author(s):  
Cai-Ning Zhao ◽  
Guo-Yi Tang ◽  
Shi-Yu Cao ◽  
Xiao-Yu Xu ◽  
Ren-You Gan ◽  
...  

Tea is among the most consumed drink worldwide, and its strong antioxidant activity is considered as the main contributor to several health benefits, such as cardiovascular protection and anticancer effect. In this study, the antioxidant activities of 30 tea infusions, which were obtained by the mimic of drinking tea of the public, from green, black, oolong, white, yellow and dark teas, were evaluated using ferric-reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, ranging from 504.80 ± 17.44 to 4647.47 ± 57.87 µmol Fe2+/g dry weight (DW) and 166.29 ± 24.48 to 2532.41 ± 50.18 µmol Trolox/g DW, respectively. Moreover, their total phenolic contents (TPC) were detected by Folin-Ciocalteu assay and were in the range of 24.77 ± 2.02 to 252.65 ± 4.74 mg gallic acid equivalent (GAE)/g DW. Generally, Dianqing Tea, Lushan Yunwu Tea, and Xihu Longjing Tea showed the strongest antioxidant activities among 30 teas. Furthermore, the phenolic compounds in tea infusions were identified and quantified, with catechins most commonly detected, especially in green tea infusions, which were main contributors to their antioxidant activities. Besides tea polyphenols, considerable content of caffeine also presented in 30 tea infusions.


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