scholarly journals Effects of Aging on Hair Color, Melanosome Morphology, and Melanin Composition in Japanese Females

2019 ◽  
Vol 20 (15) ◽  
pp. 3739 ◽  
Author(s):  
Takashi Itou ◽  
Shosuke Ito ◽  
Kazumasa Wakamatsu
Keyword(s):  
Carboxylic Acid ◽  
Aspect Ratio ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Hair Color ◽  
Age Dependent ◽  
Japanese Female ◽  
Effects Of Aging ◽  
Absorbance Spectra

In a previous study, we showed that the size of melanosomes isolated from Japanese female hairs enlarges with age, and this affects the hair color. In this study, we analyzed the age-dependent changes in hair melanin in order to further explore the factors related to hair color changing by aging. A significant positive correlation with age was found in the total melanin amount (TM) and the mol% of 5,6-dihydroxyindole (DHI) units, while no correlation was found in pheomelanin mol%. TM showed significant correlations with hair color parameters and the melanosome volume, suggesting that hair color darkening by aging is caused by the increase in TM due to the enlargement of the size of melanosome. From the measurement of absorbance spectra on synthetic eumelanins with different ratios of DHI and 5,6-dihydroxyindole-2-carboxylic acid (DHICA), we found that the increase in DHI mol% also contributes to the darkening of hair color by aging. In addition, the level of pyrrole-2,3-dicarboxylic acid (PDCA), a marker of DHI melanin, showed a significant negative correlation with the aspect ratio of melanosome, suggesting a contribution of DHI melanin to the change in melanosome morphology by aging.

scholarly journals Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1061
Author(s):  
Wajdy J. Al-Awaida ◽  
Baker Jawabrah Al Hourani ◽  
Samer Swedan ◽  
Refat Nimer ◽  
Foad Alzoughool ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Vaccine Development ◽  
Case Fatality ◽  
Significant Negative Correlation ◽  
Reference Sequence ◽  
Genome Sequences ◽  
Positive Correlation ◽  
Case Fatality Ratio ◽  
Epidemiological Surveys

The outbreak of coronavirus disease 2019 (COVID-19), by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly developed into a worldwide pandemic. Mutations in the SARS-CoV-2 genome may affect various aspects of the disease including fatality ratio. In this study, 553,518 SARS-CoV-2 genome sequences isolated from patients from continents for the period 1 December 2020 to 15 March 2021 were comprehensively analyzed and a total of 82 mutations were identified concerning the reference sequence. In addition, associations between the mutations and the case fatality ratio (CFR), cases per million and deaths per million, were examined. The mutations having the highest frequencies among different continents were Spike_D614G and NSP12_P323L. Among the identified mutations, NSP2_T153M, NSP14_I42V and Spike_L18F mutations showed a positive correlation to CFR. While the NSP13_Y541C, NSP3_T73I and NSP3_Q180H mutations demonstrated a negative correlation to CFR. The Spike_D614G and NSP12_P323L mutations showed a positive correlation to deaths per million. The NSP3_T1198K, NS8_L84S and NSP12_A97V mutations showed a significant negative correlation to deaths per million. The NSP12_P323L and Spike_D614G mutations showed a positive correlation to the number of cases per million. In contrast, NS8_L84S and NSP12_A97V mutations showed a negative correlation to the number of cases per million. In addition, among the identified clades, none showed a significant correlation to CFR. The G, GR, GV, S clades showed a significant positive correlation to deaths per million. The GR and S clades showed a positive correlation to number of cases per million. The clades having the highest frequencies among continents were G, followed by GH and GR. These findings should be taken into consideration during epidemiological surveys of the virus and vaccine development.

scholarly journals Evaluation of serum adropin and irisin levels and its association with anthropometric obesity indices and biochemical parameters in Type 2 diabetic patients

2021 ◽  
pp. 1-8
Author(s):  
Foad Alzoughool ◽  
Huda Al Hourani ◽  
Manar Atoum ◽  
Sajedah Bateineh ◽  
Hanan Alsheikh ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Biochemical Parameters ◽  
Significant Positive Correlation ◽  
Glycosylated Hemoglobin ◽  
Significant Negative Correlation ◽  
Diabetic Patients ◽  
Positive Correlation ◽  
Obesity Indices ◽  
Group Serum

BACKGROUND/AIM: The newly described proteins adropin and irisin are a highly conserved polypeptide that plays essential roles in metabolic and energy homeostasis, insulin resistance, and fat browning. The aim of this study is to evaluate the circulating levels of serum adropin and irisin in type 2 diabetes mellitus (T2DM) patients and also to elucidate possible relationships between serum adropin and irisin levels with anthropometric obesity indices and biochemical parameters. SUBJECTS AND METHODS: Single-center prospective observational study included 90 T2DM patients referred to the diabetes outpatient clinic. Height, weight, and waist circumference (WC) were measured. Body mass index (BMI) and waist to height ratio (WHtR) were calculated. Fasting blood glucose, glycosylated hemoglobin, serum lipids, creatinine, urea, and blood urea nitrogen were evaluated. Estimated glomerular filtration rate (GFR) was calculated, serum adropin and irisin were evaluated. RESULTS: The results showed a significant positive correlation between adropin and irisin in females but not in males (r = 0.311; P = 0.042). In males’ group, serum adropin levels showed significant negative correlation with serum glucose (–0.423, P = <  0.05), HbA1C (–0.364, P = <  0.05), and GFR (–0.355, P = <  0.05). In contrast, creatinine was showed a significant positive correlation with adropin in males (0.381, P = <  0.05). In females’ group, adropin showed a significant negative correlation with weight (–0.371, P = <  0.05), BMI (–0.349, P = <  0.05), WC (–0.402, P = <  0.01), and WHtR (–0.398, P = <  0.01). Contrary, in males’ group, serum irisin levels showed significant positive correlation with weight (0.338, P = <  0.05), BMI (0.332, P = <  0.05), WC (0.409, P = <  0.01), and WHtR (0.432, P = <  0.01). CONCLUSION: This study demonstrated that, in T2DM patients, circulating serum adrpoin correlated negatively with anthropometric obesity indices of obesity in females, while serum irisin was positively correlated with anthropometric obesity indices of obesity in males.

Increased plasma kynurenine and its relationship to neopterin and tryptophan in Tourette's syndrome

1996 ◽  
Vol 26 (4) ◽  
pp. 857-862 ◽  
Author(s):  
H. Rickards ◽  
S. M. Dursun ◽  
G. Farrar ◽  
T. Betts ◽  
J. A. Corbett ◽  
...  
Keyword(s):  
Tourette Syndrome ◽  
Negative Correlation ◽  
Plasma Levels ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Healthy Controls ◽  
Positive Correlation ◽  
Control Value ◽  
Cellular Immune ◽  
Patient Value

SynopsisFasting plasma levels of tryptophan, kynurenine and the pteridines, neopterin and tetrahydrobiopterin were measured in seven patients with Gilles de la Tourette syndrome (GTS) and 10 healthy controls. Plasma kynurenine was significantly elevated in the GTS patients. The lowest patient value was higher than the highest control value. Values for tryptophan, neopterin and tetrahydrobiopterin were similar in TS patients and controls. However, in TS patients only, there was a significant negative correlation between tryptophan and neopterin and a significant positive correlation between kynurenine and neopterin when controlling for tryptophan. This finding indicates that activation of cellular immune processes is a possible explanation for the rise in plasma kynurenine.

Morpho-Biochemical Characteristics of Brinjal Germplasms Affect the Abundance And Infestation of Jassid

2021 ◽  
Vol 19 (1) ◽  
pp. 81-91
Author(s):  
F Yasmin ◽  
MR Amin ◽  
M Afroz ◽  
MAH Swapon ◽  
MM Hossain
Keyword(s):  
Protein Content ◽  
Chlorophyll Content ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Reducing Sugar ◽  
Total Sugar ◽  
The Other ◽  
Biochemical Characteristics ◽  
Positive Correlation

The tropical vegetable, brinjal is cultivated throughout the year in Bangladesh but the crop is infested by a number of insects including jassid. This study investigated the effects of different biophysical and biochemical characteristics of twelve brinjal germplasms on the abundance and infestation of jassid. The experiment was conducted during September 2018 to March 2019 in Gazipur, Bangladesh with twelve brinjal germplasms namely BD-7320, BD-7328, BD-9952, BD-10154, BD-10158, BARI Begun-1, BARI Begun-4, BARI Begun-5, BARI Begun- 6, BARI Begun-7, BARI Begun-8 and BARI Begun-9. The incidence of jassid was recorded from 3rd December to 26th March, and the lowest population was found on BARI Begun- 6. Among the biophysical traits, plant height, number of branch and leaf per plant, and leaf area exerted significant positive correlation; whereas trichome on lower and upper surfaces of leaf, spine per stem and leaf showed significant negative correlation with the abundance of jassid. On the other hand, moisture, reducing sugar, total sugar and protein content of the leaves and fruits, chlorophyll content of the leaves exerts significant positive correlation but ash and pH contents of the leaves and fruits were negatively correlated with the abundance of jassid. Jassids showed the lowest level of leaf infestation on BARI Begun-6, which could be for further analysis to develop jassid resistant brinjal. SAARC J. Agric., 19(1): 81-91 (2021)

scholarly journals A Mediator Effect of Social Support in the Association between Stress for College Life and Depression among Nursing Students

2019 ◽  
Vol 25 (1) ◽  
pp. 125-135
Author(s):  
Kyung Hee Yoo
Keyword(s):  
Social Support ◽  
Nursing Students ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Nursing Intervention ◽  
Descriptive Statistics ◽  
Self Report ◽  
College Life ◽  
Significant Mediator

Purpose: This study was conducted to determine the mediator effect of social support in the association between stress for college life and depression among nursing students. Methods: The participants of the study were 201 university students in A and C cities. Self-report questionnaires were used to measure the variables. In the data analysis, the SPSSWIN 25.0 program was utilized for descriptive statistics, Pearson's correlation, Sobel test and multiple regression analysis. Results: Mean scores of stress for college life, depression and social support were 2.56, 4.12 and 0.61, respectively. Stress for college life and depression showed a significant positive correlation (r=.60, p<.001), while depression and social support showed a significant negative correlation (r=-.46, p<.001). Lastly, stress for college life and social support showed a significant negative correlation (r=-.55, p<.001). The analysis of the mediator effect of social support in the association between stress for college life and depression showed that social support had a significant mediator effect. Conclusion: Among nursing students, social support may be a mediator in the association between stress for college life and depression. Therefore, strategies for nursing intervention to improve social support should be developed for nursing students.

scholarly journals THE CORRELATION OF MOBILITY TREND AND SITUATION OF COVID-19 BY COUNTRY, TERRITORY, AND AREA

2021 ◽  
Vol 8 (3) ◽  
pp. 153-164
Author(s):  
Adrina Esther Liaw ◽  
Jihan Natra Shafira ◽  
Muhammad Aziz ◽  
Iche Andriyani Liberty
Keyword(s):  
Negative Correlation ◽  
Government Policy ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Research Paper ◽  
Analytic Study ◽  
Cross Sectional ◽  
Positive Correlation ◽  
The World ◽  
The Government

Each country around the world has taken several approaches in order to stop the spreading of the virus. This study was conducted to correlate the mobility trend and the situation of COVID-19 by country, territory, and area. This research paper adopts an observational analytic study with a cross-sectional approach for 115 countries from February 17th to August 27th, 2020. Tajikistan (r=0,956) and Italy (r=0,931) has the highest positive correlation for retail and recreations. For grocery,the highest degree of positive correlation is Mongolia (r=0,945) and Tajikistan (r=0,933). Bostwana and Italy showed highest significant positive correlation among countries (r=0,985 and r=0,902, respectively) for transit stations and residential  (r=0,994 and r=0,984). Bostwana also has the highest significant positive correlation for the park (r=0.980). Meanwhile, for the workplace, Mauritius (r=0,863) and Dominica (r=0,785) are countries with the highest degree of positive correlation with a cumulative case of COVID-19. Society's behavior plays an important role by following the government policy in order to slow down the spread of the virus. Retail and recreations, groceries and pharmacy stores, transit stations, parks, and workplaces found to have a significant positive correlation while residential have a significant negative correlation with cumulative cases of COVID-19 in most countries.  

scholarly journals Analysis of the Correlation between Commodity Grade and Quality ofAngelica sinensisby Determination of Active Compounds Using Ultraperformance Liquid Chromatography Coupled with Chemometrics

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Zenghui Wang ◽  
Dongmei Wang ◽  
Linfang Huang
Keyword(s):  
Ferulic Acid ◽  
Bioactive Compounds ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Principal Component ◽  
Significant Negative Correlation ◽  
Average Weight ◽  
Positive Correlation ◽  
Grade Classification ◽  
The Difference

The contents of ferulic acid, senkyunolide A, butylidenephthalide, ligustilide, and n-butylphthalide were determined by UPLC analytical method; the correlation among the grade, average weight, and content was explored by correlation analysis and analysis of variance (ANOVA); the different commercial grades with average weight and content were revealed by principal component analysis (PCA) and then rationality analysis grade classification ofA. sinensis. The results showed that various commercial grades can be distinguished by PCA analysis. And there was significant negative correlation between the commodity grades and average weight, commodity, and the content of bioactive compounds, while the content of senkyunolide A had significant negative correlation with commodity grades (P<0.01). Average weight had no correlation with chemicals compounds. Additionally, there was significant positive correlation among the bioactive compounds (content of ferulic acid and phthalides) of different grades ofA. sinensis. The content of senkyunolide A, butylidenephthalide, and ligustilide had significant positive correlation with the content of ferulic acid. The content of ligustilide and butylidenephthalide had significant positive correlation with the content of senkyunolide A. The content of ligustilide had significant positive correlation with the content of butylidenephthalide. The basis of grades classification is related with the difference levels of the bioactive compounds.

The Hla System and the Clinical Response to Treatment with Chlorpromazine

1976 ◽  
Vol 129 (5) ◽  
pp. 486-489 ◽  
Author(s):  
E. Smeraldi ◽  
L. Bellodi ◽  
E. Sacchetti ◽  
C. L. Cazzullo
Keyword(s):  
Clinical Response ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Response To Treatment ◽  
Positive Correlation ◽  
Hla System ◽  
Schizophrenic Patients ◽  
Clinical Responses ◽  
Pre Treatment

SummaryA group of 33 schizophrenic patients were typed for HLA-SD antigens and their qualitative clinical responses to chlorpromazine therapy determined. A highly significant positive correlation was found between response to chlorpromazine and HLA-A1 positive, while HLA-A2 positive subjects showed a significant negative correlation to chlorpromazine treatment.In a second group of 17 patients the clinical responses to chlorpromazine were evaluated quantitatively, by WPRS, in HLA-A1 positive and HLA-A1 negative patients. There were no pre-treatment differences in the scores. After treatment the scores of positive patients were significantly lower, indicating that they responded to a greater degree.Since the frequency of HLA-A1 in hebephrenic patients is higher than that in other schizophrenics this may explain our earlier finding that hebephrenics, as a group, respond better to chlorpromazine than do other schizophrenics.

scholarly journals SUITABILITY OF SPRING CEREALS FOR PRODUCTION OF HEAT ENERGY

2015 ◽  
Vol 1 ◽  
pp. 24
Author(s):  
Ina Belicka ◽  
Viktorija Miglāne ◽  
Zaiga Jansone
Keyword(s):  
Renewable Energy ◽  
Chemical Composition ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Significant Negative Correlation ◽  
Heat Energy ◽  
Heating Capacity ◽  
Cereal Breeding ◽  
Cereal Species ◽  
Spring Cereals

In future biomass are planned as main source as renewable energy. The grain and straw are as one of the representatives of biomass. During 2007 - 2008 in the State Stende Cereal Breeding Institute the investigations were carried out to define more accurately spring cereal–wheat, barley and oats for heat production. In the field experiment were sown 4 - 6 varieties from each species. The yield, chemical composition, the highest and lowest heating capacity of grain and straw were evaluated. The highest heating capacity for grain was 15475 - 16994 and the lowest – 13828 - 15356 kJ kg-1; in straw – 15788 - 16840 and 14106 - 15230 kJ kg-1respectively. Accordingly to this value the cereal species arranged in the following order: oats, barley and wheat. The varieties of cereal were differed in heating capacity depending on chemical composition. Significant positive correlation was observed between grain heating capacity and fat (r = 0.993; r0.01 = 0.684), and fiber (r= 0.838; r0.01 = 0.684), but significant negative correlation with starch (r = - 0.847; r0.01 = 0.684).

scholarly journals Correlation and path coefficients analyses in Basmati rice

2015 ◽  
Vol 40 (1) ◽  
pp. 153-161 ◽  
Author(s):  
M Ratna ◽  
S Begum ◽  
A Husna ◽  
SR Dey ◽  
MS Hossain
Keyword(s):  
Plant Height ◽  
Direct Effect ◽  
Negative Correlation ◽  
Significant Positive Correlation ◽  
Correlation Coefficients ◽  
Significant Negative Correlation ◽  
Basmati Rice ◽  
Panicle Length ◽  
Path Coefficients ◽  
Level Number

Correlation and path coefficients analyses among fourteen morphological characters were studied in six advanced lines of Basmati rice and one commercial check namely BRRI Dhan 29. In general, genotypic correlation coefficients were higher than the corresponding phenotypic correlation coefficients suggesting that the environmental influence reduces the relationship between yield and yield contributing characters of rice. Correlation coefficient analysis showed significant positive correlation between plant height and panicle length at genotypic level. Number of filled spikelets/panicle showed significant positive correlation with yield at both genotypic and phenotypic levels but significant negative correlation was observed between plant height and yield. Number of effective tillers/plant had negative significant correlation with panicle length and with number of unfilled spikelets/panicle at genotypic level. Number of ineffective tillers/plant had significant negative correlation with 1000-seed weight at both genotypic and phenotypic levels. Path coefficient analysis revealed highest positive direct effect of number of filled spikelets/panicle on grain yield but plant height and number of unfilled spikelets/panicle had negative direct effect on grain.Bangladesh J. Agril. Res. 40(1): 153-161, March 2015

Sign in / Sign up

Export Citation Format

Share Document