scholarly journals Current Trends in Metallic Orthopedic Biomaterials: From Additive Manufacturing to Bio-Functionalization, Infection Prevention, and Beyond

2018 ◽  
Vol 19 (9) ◽  
pp. 2684 ◽  
Author(s):  
Amir Zadpoor

There has been a growing interest in metallic biomaterials during the last five years, as recent developments in additive manufacturing (=3D printing), surface bio-functionalization techniques, infection prevention strategies, biodegradable metallic biomaterials, and composite biomaterials have provided many possibilities to develop biomaterials and medical devices with unprecedented combinations of favorable properties and advanced functionalities. Moreover, development of biomaterials is no longer separated from the other branches of biomedical engineering, particularly tissue biomechanics, musculoskeletal dynamics, and image processing aspects of skeletal radiology. In this editorial, I will discuss all the above-mentioned topics, as they constitute some of the most important trends of research on metallic biomaterials. This editorial will, therefore, serve as a foreword to the papers appearing in a special issue covering the current trends in metallic biomaterials.

Author(s):  
Nabi Sertac Artan

The mission of this chapter is to introduce the reader the recent developments in the design of ultra-Low Power ADCs for Wearable and Implantable Medical Devices (WIMDs). The focus of this chapter will be on Signal-Adaptive Successive Approximation Register (SAR) ADC architectures and their derivatives, since the majority of the ULP medical devices rely on these architectures. The proposed chapter first provides an overview of the WIMDs, and electrophysiological signals. Then, basic SAR ADCs are introduced followed by the study of adaptive SAR ADCs. The chapter concludes with a brief summary of the other prevalent ADC architecture for WIMDs, namely the Level-Crossing ADCs.


2019 ◽  
Vol 13 (3) ◽  
pp. 329-329
Author(s):  
Tatsuaki Furumoto

Additive manufacturing (AM) with metals is currently one of the most promising techniques for 3D-printed structures, as it has tremendous potential to produce complex, lightweight, and functionally-optimized parts. The medical, aerospace, and automotive industries are some of the many expected to reap particular benefits from the ability to produce high-quality models with reduced manufacturing costs and lead times. The main advantages of AM with metals are the flexibility of the process and the wide variety of metal materials that are available. Various materials, including steel, titanium, aluminum alloys, and nickel-based alloys, can be employed to produce end products. The objective of this special issue is to collect recent research works focusing on AM with metals. This issue includes 5 papers covering the following topics: ===danraku===- Powder bed fusion (PBF) ===danraku===- Directed energy deposition (DED) ===danraku===- Wire and arc-based AM (WAAM) ===danraku===- Binder jetting (BJT) ===danraku===- Fused deposition modeling (FDM) This issue is expected to help readers understand recent developments in AM, leading to further research. We deeply appreciate the contributions of all authors and thank the reviewers for their incisive efforts.


Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1696 ◽  
Author(s):  
Jarosław Jakubowicz

In the last half century, great attention has been paid to materials that can be used in the human body to prepare parts that replace failed bone structures. Of all materials, Ti-based materials are the most desirable, because they provide an optimum combination of mechanical, chemical and biological properties. The successful application of Ti biomaterials has been confirmed mainly in dentistry, orthopedics and traumatology. The Ti biomaterials provide high strength and a relatively low Young’s modulus. Titanium biocompatibility is practically the highest of all metallic biomaterials, however new solutions are being sought to continuous improve their biocompatibility and osseointegration. Thus, the chemical modification of Ti results in the formation of new alloys or composites, which provide new perspectives for Ti biomaterials applications. Great attention has also been paid to the formation of nanostructures in Ti-based biomaterials, which has leads to extremely good mechanical properties and very good biocompatibility. Additionally, the surface treatment applied to Ti-based biomaterials provides faster osseointegration and improve in many cases mechanical properties. The special issue “Ti-Based Biomaterials: Synthesis, Properties and Applications” has been proposed as a means to present recent developments in the field. The articles included in the special issue cover broad aspects of Ti-based biomaterials formation with respect to design theirs structure, mechanical and biological properties, as highlighted in this editorial.


Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 4046
Author(s):  
Jingwei Zhao ◽  
Zhengyi Jiang ◽  
Leszek A. Dobrzański ◽  
Chong Soo Lee ◽  
Fuxiao Yu

Product miniaturization is a trend for facilitating product usage, enabling product functions to be implemented in microscale geometries, and aimed at reducing product weight, volume, cost and pollution. Driven by ongoing miniaturization in diverse areas including medical devices, precision equipment, communication devices, micro-electromechanical systems (MEMS) and microsystems technology (MST), the demands for micro metallic products have increased tremendously. Such a trend requires development of advanced micromanufacturing technology of metallic materials for producing high-quality micro metallic products that possess excellent dimensional tolerances, required mechanical properties and improved surface quality. Micromanufacturing differs from conventional manufacturing technology in terms of materials, processes, tools, and machines and equipment, due to the miniaturization nature of the whole micromanufacturing system, which challenges the rapid development of micromanufacturing technology. Against such a background, the Special Issue “Micromanufacturing of Metallic Materials” was proposed to present the recent developments of micromanufacturing technologies of metallic materials. The papers collected in the Special Issue include research articles, literature review and technical notes, which have been highlighted in this editorial.


2018 ◽  
pp. 413-443
Author(s):  
Nabi Sertac Artan

The mission of this chapter is to introduce the reader the recent developments in the design of ultra-Low Power ADCs for Wearable and Implantable Medical Devices (WIMDs). The focus of this chapter will be on Signal-Adaptive Successive Approximation Register (SAR) ADC architectures and their derivatives, since the majority of the ULP medical devices rely on these architectures. The proposed chapter first provides an overview of the WIMDs, and electrophysiological signals. Then, basic SAR ADCs are introduced followed by the study of adaptive SAR ADCs. The chapter concludes with a brief summary of the other prevalent ADC architecture for WIMDs, namely the Level-Crossing ADCs.


2018 ◽  
Vol 7 (4) ◽  
pp. 126
Author(s):  
Levi Perez

There are several arguments why the economic and management analysis of gambling seems to be very interesting. Gambling is a relevant worldwide market from which either local or national governments obtain resources due to some sort of fiscal imposition on gambling participation. On the other hand, gambling is also a social phenomenon with potential risks to society and the consumption of gambling seems to violate the premises of economic theory (risk aversion, maximizing and rational conduct). The aim of this special issue is to provide an outlet for recent developments in gambling-related research encompassing topics on sports betting, responsible gambling, lottery markets and online gambling, among others.


2013 ◽  
Vol 135 (06) ◽  
pp. S13-S16 ◽  
Author(s):  
Jun Ueda ◽  
David B. Comber ◽  
Jonathon Slightam ◽  
Melih Turkseven ◽  
Vito Gervasi ◽  
...  

This article introduces recent developments and challenges related to magnetic resonance imaging (MRI)-compatible medical devices. Recent advances in fluid-powered medical devices are described, including a needle steering robot for neurosurgery and a haptic device for hemiplegia rehabilitation. Recent three-dimensional printing technologies for fabricating integrated fluid-powered robots are also reported. The use of additive manufacturing conjoined with modern digital imaging techniques allow for the customization of components, a trait that is generally needed in medical implants and devices. Furthermore, the materials that are available in additive processes allow for direct end-use production of customized components and devices. In addition, the polymer-based materials have an inherently low permeability, allowing for use in an MRI environment while not causing imaging interference. Presently, selective laser sintering (SLS), stereolithography, and extrusion processes illustrate and suggest that they offer the greatest promise in MRI compatible end-use components. Future work is aimed at using Additive Manufacturing (AM) to develop inherently safe, compact, MRI compatible medical devices.


2021 ◽  
Vol 11 (2) ◽  
pp. 840 ◽  
Author(s):  
Roberto Citarella ◽  
Venanzio Giannella

The advent of additive manufacturing (AM) processes applied to the fabrication of structural components has created the need for design methodologies and structural optimization approaches that take into account the specific characteristics of the fabrication process. While AM processes give unprecedented geometrical design freedom, which can result in significant reductions in the components’ weight (e.g., through part count reduction), on the other hand, they have implications for the fatigue and fracture strength, because of residual stresses and microstructural features. This is due to stress concentration effects, anisotropy, distortions and defects whose effects still need investigation. This Special Issue aims at gathering together research investigating the different features of AM processes with relevance for their structural behavior, particularly, but not exclusively, from the viewpoints of fatigue, fracture and crash behavior. Although the focus of this Special Issue is on AM, articles dealing with other manufacturing processes with related analogies can also be included, in order to establish differences and possible similarities.


2018 ◽  
pp. 231-261
Author(s):  
Nabi Sertac Artan

The mission of this chapter is to introduce the reader the recent developments in the design of ultra-Low Power ADCs for Wearable and Implantable Medical Devices (WIMDs). The focus of this chapter will be on Signal-Adaptive Successive Approximation Register (SAR) ADC architectures and their derivatives, since the majority of the ULP medical devices rely on these architectures. The proposed chapter first provides an overview of the WIMDs, and electrophysiological signals. Then, basic SAR ADCs are introduced followed by the study of adaptive SAR ADCs. The chapter concludes with a brief summary of the other prevalent ADC architecture for WIMDs, namely the Level-Crossing ADCs.


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