scholarly journals The Influence of Inflammation and Nerve Damage on the Neurochemical Characterization of Calcitonin Gene-Related Peptide—Like Immunoreactive (CGRP-LI) Neurons in the Enteric Nervous System of the Porcine Descending Colon

2018 ◽  
Vol 19 (2) ◽  
pp. 548 ◽  
Author(s):  
◽  
Keyword(s):  
Nervous System ◽  
Enteric Nervous System ◽  
Calcitonin Gene Related Peptide ◽  
Nerve Damage ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Descending Colon

scholarly journals Age and Sex-Dependent Differences in the Neurochemical Characterization of Calcitonin Gene-Related Peptide-Like Immunoreactive (CGRP-LI) Nervous Structures in the Porcine Descending Colon

2019 ◽  
Vol 20 (5) ◽  
pp. 1024 ◽  
Author(s):  
Krystyna Makowska ◽  
Slawomir Gonkowski
Keyword(s):  
Calcitonin Gene Related Peptide ◽  
Colonic Wall ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Adaptive Processes ◽  
Descending Colon ◽  
And Gender ◽  
Oxide Synthase

Neurons of the enteric nervous system (ENS) may undergo changes during maturation and aging, but knowledge of physiological stimuli-dependent changes in the ENS is still fragmentary. On the other hand, the frequency of many ENS-related intestinal illnesses depends on age and/or sex. The double immunofluorescence technique was used to study the influence of both of these factors on calcitonin gene-related peptide (CGRP)—positive enteric nervous structures—in the descending colon in young and adult female and castrated male pigs. The influence of age and gender on the number and neurochemical characterization (i.e., co-localization of CGRP with substance P, nitric oxide synthase, galanin, cocaine- and amphetamine-regulated transcript peptide and vesicular acetylcholine transporter) of CGRP-positive nerve structures in the colonic wall has been shown. These observations strongly suggest the participation of CGRP in adaptive processes in the ENS during GI tract maturation. Moreover, although the castration of males may mask some aspects of sex-dependent influences on the ENS, the sex-specific differences in CGRP-positive nervous structures were mainly visible in adult animals. This may suggest that the distribution and exact role of this substance in the ENS depend on the sex hormones.

Calcitonin Gene-Related Peptide in Morphologically Well-Defíned Type II Neurons of the Enteric Nervous System in the Porcine Small Intestine

1987 ◽  
Vol 129 (4) ◽  
pp. 325-328 ◽  
Author(s):  
Dietrich W. Scheuermann ◽  
Werner Stach ◽  
Marie H.A. De Groodt-Lasseel ◽  
Jean-Pierre Timmermans
Keyword(s):  
Nervous System ◽  
Small Intestine ◽  
Enteric Nervous System ◽  
Calcitonin Gene Related Peptide ◽  
Type Ii ◽  
Related Peptide ◽  
Calcitonin Gene

Expression of α-calcitonin gene-related peptide in the enteric nervous system of rat small intestine

2000 ◽  
Vol 285 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Yoshiaki Doi ◽  
Hong Peng ◽  
Hideaki Kudo ◽  
Kunshige Hamasaki ◽  
Sunao Fujimoto
Keyword(s):  
Nervous System ◽  
Small Intestine ◽  
Enteric Nervous System ◽  
Calcitonin Gene Related Peptide ◽  
Rat Small Intestine ◽  
Related Peptide ◽  
Calcitonin Gene

Solubilization and Characterization of Calcitonin Gene-Related Peptide Binding Site from Porcine Spinal Cord

1988 ◽  
Vol 50 (2) ◽  
pp. 480-485 ◽  
Author(s):  
Osamu Hiroshima ◽  
Yoshihisa Sano ◽  
Teruaki Yuzuriha ◽  
Chiyuki Yamato ◽  
Akira Saito ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Binding Site ◽  
Peptide Binding ◽  
Calcitonin Gene Related Peptide ◽  
Related Peptide ◽  
Calcitonin Gene ◽  
Peptide Binding Site

Comparative immunohistochemical distribution of amylin-like and calcitonin gene related peptide like immunoreactivity in the rat central nervous system

1995 ◽  
Vol 73 (7) ◽  
pp. 945-956 ◽  
Author(s):  
Gerhard Skofitseh ◽  
Wolfgang Gubisch ◽  
Sunil J. Wimalawansa ◽  
David M. Jacobowitz
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebellar Nuclei ◽  
Calcitonin Gene Related Peptide ◽  
Polyclonal Antiserum ◽  
Related Peptide ◽  
Diagonal Band ◽  
Large Numbers ◽  
Calcitonin Gene ◽  
The Central Nervous System

Using the indirect immunofluorescence method with a polyclonal antiserum raised in rabbits and directed against amylin (AMY), we have investigated the distribution of AMY-like immunoreactivity (-ir) throughout the central nervous system of the rat. The widespread distribution of AMY-ir was much more abundant than that previously reported for calcitonin gene related peptide (CGRP) immunoreactivity. In most brain areas there was no overlap between AMY- and CGRP-ir cell body groupings, with the exception of the motor nuclei of the hindbrain and spinal cord, which were found to contain large numbers of AMY- and CGRP-immunoreactive cell bodies. Areas with a moderate to dense appearance of AMY-ir were the rhinencephalon, the nucleus of the diagonal band, the magnocellular, dorso- and ventro-medial and mammillary nuclei of the hypothalamus, the habenula, the compact part of the substantia nigra, the ruber and pontine nuclei, and the inferior olive and the cerebellar nuclei. The widespread immunohistochemical distribution of AMY-ir in the rat brain is in partial agreement with the distribution of AMY-binding sites.Key words: calcitonin gene related peptide, amylin, central nervous system, immunohistochemistry, rat.

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