scholarly journals The Role of Glyoxalase-I (Glo-I), Advanced Glycation Endproducts (AGEs), and Their Receptor (RAGE) in Chronic Liver Disease and Hepatocellular Carcinoma (HCC)

2017 ◽  
Vol 18 (11) ◽  
pp. 2466 ◽  
Author(s):  
Marcus Hollenbach
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Advanced Glycation Endproducts ◽  
Chronic Liver ◽  
Glyoxalase I ◽  
Advanced Glycation ◽  
Glycation Endproducts

scholarly journals Sequential Occurrence of Hepatocellular Carcinoma Following Waldenstroem's Macroglobulinemia: The Pathogenetic Role of Chronic Liver Disease.

1996 ◽  
Vol 35 (5) ◽  
pp. 416-418 ◽  
Author(s):  
Tohru IZUMI ◽  
Ryuhei SASAKI ◽  
Saburo TSUNODA ◽  
Makio HATAKEYAMA ◽  
Hirotaka KOYAMA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Pathogenetic Role

P606 THE ROLE OF TGF-β2 IN CHRONIC LIVER DISEASE (CLD) AND HEPATOCELLULAR CARCINOMA (HCC)

2014 ◽  
Vol 60 (1) ◽  
pp. S271
Author(s):  
A. Dropmann ◽  
T. Dediulia ◽  
S. Weber ◽  
K. Abshagen ◽  
M. Wieland ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver

Role of Ultrasound for Chronic Liver Disease and Hepatocellular Carcinoma Surveillance

2021 ◽  
Vol 29 (3) ◽  
pp. 279-290
Author(s):  
Hailey H. Choi ◽  
Shuchi K. Rodgers ◽  
Aman Khurana ◽  
Leslie W. Nelson ◽  
Aya Kamaya
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Hepatocellular Carcinoma Surveillance

Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers

2010 ◽  
Vol 25 (1) ◽  
pp. 129-137 ◽  
Author(s):  
Pisit Tangkijvanich ◽  
Theerawut Chanmee ◽  
Sanpoj Komtong ◽  
Varocha Mahachai ◽  
Naruemon Wisedopas ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Liver Cancers ◽  
Diagnostic Role

Functional role of CCL5/RANTES for hepatocellular carcinoma progression during chronic liver disease

2017 ◽  
Vol 66 (1) ◽  
pp. S227-S228 ◽  
Author(s):  
A. Mohs ◽  
N. Kuttkat ◽  
J. Reißing ◽  
H.W. Zimmermann ◽  
R. Sonntag ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Functional Role ◽  
Chronic Liver

Insulin Resistance and Hyperinsulinemia in Patients with Chronic Liver Disease and Hepatocellular Carcinoma

2009 ◽  
Vol 2 ◽  
pp. CMED.S3116 ◽  
Author(s):  
Valter Donadon ◽  
Massimiliano Balbi ◽  
Antonio Perciaccante ◽  
Pietro Casarin ◽  
Giorgio Zanette
Keyword(s):  
Hepatocellular Carcinoma ◽  
Insulin Resistance ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Healthy Subjects ◽  
Chronic Liver ◽  
Metabolic Factors ◽  
Mean Values ◽  
The Mean

Objectives To investigate the role of insulin resistance (IR) and insulin plasma levels (IRI) in patients with chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Methods We recruited the following patients: 125 with HCC, 128 with liver cirrhosis (LC) and 133 with chronic hepatitis C (CHC). IR was assessed by the HOMA-IR method. To define IR and hyperinsulinemia we selected as a cut-off level, the value of the 80th percentile for HOMA-IR (2.72) and IRI (11.18) in 113 healthy subjects. Results The mean levels of HOMA-IR and IRI increase progressively among CHC (2.7 ± 2.9 and 11.5 ± 10.5, respectively), LC (5.4 ± 4.5 and 17.6 ± 11.2) and HCC (6.4 ± 9.8 and 18.2 ± 18.8). In the upper quintiles for HOMA-IR and IRI, the frequency of patients in the LC and HCC groups was twice as much in CHC cases. HCC with DM2 have the greatest percentage above the 80th percentile of HOMA-IR, their quintiles distribution is inverted and HOMA-IR mean values are significantly higher in comparison with HCC without DM2 cases. Discussion Our study shows that the association between IR and CLD begins in the early stages of liver fibrosis. DM2 increases HOMA-IR and IRI mean levels in HCC patients and these metabolic factors could play a major role in the link between diabetes mellitus and hepatocarcinoma.

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