scholarly journals Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells

2017 ◽  
Vol 18 (6) ◽  
pp. 1132 ◽  
Author(s):  
Hsi-Hsien Hsu ◽  
Yueh-Min Lin ◽  
Chia-Yao Shen ◽  
Marthandam Shibu ◽  
Shin-Yi Li ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prostaglandin E2 ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Colon Cancer Cells ◽  
Cox 2

scholarly journals Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation

2017 ◽  
Vol 23 (7) ◽  
pp. 1171 ◽  
Author(s):  
Hsi-Hsien Hsu ◽  
Ming-Cheng Chen ◽  
Cecilia Hsuan Day ◽  
Yueh-Min Lin ◽  
Shin-Yi Li ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prostaglandin E2 ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Cox 2 ◽  
Human Colon Cancer Cells

scholarly journals THE INHIBITION OF POLYISOPRENOIDS FROM NYPA FRUTICANS LEAVES ON CYCLOOXYGENASE 2 EXPRESSION OF WIDR COLON CANCER CELLS

2018 ◽  
Vol 11 (8) ◽  
pp. 154 ◽  
Author(s):  
Dini Permata Sari ◽  
Mohammad Basyuni ◽  
Poppy Anjelisa Zaitun Hasibuan ◽  
Ridha Wati
Keyword(s):  
Colon Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Colon Cancer Cell ◽  
Cyclooxygenase 2 ◽  
Colon Cancer Cells ◽  
Chemopreventive Agents ◽  
Nypa Fruticans ◽  
Diphenyltetrazolium Bromide ◽  
Cox 2

Objective: The objective of the study was to investigate the inhibitory activity of polyisoprenoids from Nypa fruticans leaves on the expression of cyclooxygenase 2 (COX-2) against colon cancer cells.Methods: Anticancer activity performed was tested by dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method on colon cancer cell WiDr. The expression of COX-2 was observed by the immunocytochemistry method.Result: Polyisoprenoids from N. fruticans leaves exhibit anticancer activity on WiDr cells through inhibition of COX-2 expression with IC50 180.186±7.16 μg/ml.Conclusions: This study showed that polyisoprenoids from N. fruticans leaves promise chemopreventive agents for colon cancer through COX-2 inhibition.

Dual regulation of IGF-1 receptor expression by COX-2 and angiotensin II in colon cancer cells: A possible implication for cancer chemoprevention

2001 ◽  
Vol 120 (5) ◽  
pp. A594
Author(s):  
Masakazu Yasumaru ◽  
Shingo Tsuji ◽  
Masahiko Tsujii ◽  
Naoki Kawai ◽  
Arata Kimura ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Angiotensin Ii ◽  
Cancer Cells ◽  
Cancer Chemoprevention ◽  
Receptor Expression ◽  
Colon Cancer Cells ◽  
Cox 2
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