scholarly journals Vanillin Suppresses Cell Motility by Inhibiting STAT3-Mediated HIF-1α mRNA Expression in Malignant Melanoma Cells

2017 ◽  
Vol 18 (3) ◽  
pp. 532 ◽  
Author(s):  
Eun-Ji Park ◽  
Yoon-Mi Lee ◽  
Taek-In Oh ◽  
Byeong Kim ◽  
Beong-Ou Lim ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Cell Motility ◽  
Mrna Expression ◽  
Melanoma Cells

scholarly journals Mechanical Intermittent Compression Affects the Progression Rate of Malignant Melanoma Cells in a Cycle Period-Dependent Manner

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1112
Author(s):  
Takashi Morikura ◽  
Shogo Miyata
Keyword(s):  
Malignant Melanoma ◽  
Mrna Expression ◽  
Melanoma Cells ◽  
Cycle Period ◽  
Progression Rate ◽  
Dependent Manner ◽  
Mechanical Compression ◽  
Dynamic Mechanical ◽  
Intermittent Compression ◽  
Mrna Expression Levels

Static mechanical compression is a biomechanical factor that affects the progression of melanoma cells. However, little is known about how dynamic mechanical compression affects the progression of melanoma cells. In the present study, we show that mechanical intermittent compression affects the progression rate of malignant melanoma cells in a cycle period-dependent manner. Our results suggest that intermittent compression with a cycle of 2 h on/2 h off could suppress the progression rate of melanoma cells by suppressing the elongation of F-actin filaments and mRNA expression levels related to collagen degradation. In contrast, intermittent compression with a cycle of 4 h on/4 h off could promote the progression rate of melanoma cells by promoting cell proliferation and mRNA expression levels related to collagen degradation. Mechanical intermittent compression could therefore affect the progression rate of malignant melanoma cells in a cycle period-dependent manner. Our results contribute to a deeper understanding of the physiological responses of melanoma cells to dynamic mechanical compression.

scholarly journals Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway

2019 ◽  
Vol 10 (5) ◽  
pp. 1197-1208 ◽  
Author(s):  
Qianqian Zhang ◽  
Xianguang Meng ◽  
Guojing Qin ◽  
Xiaotong Xue ◽  
Ningning Dang
Keyword(s):  
Malignant Melanoma ◽  
Signaling Pathway ◽  
Melanoma Cells ◽  
Akt Signaling ◽  
Akt Signaling Pathway ◽  
Lyn Kinase

Characteristics of Malignant Melanoma Cells in the Treatment With Fast Neutrons

1989 ◽  
Vol 2 (4) ◽  
pp. 372-378 ◽  
Author(s):  
HIROSHI TSUNEMOTO ◽  
SHINROKU MORITA ◽  
SHUNJI MORI
Keyword(s):  
Malignant Melanoma ◽  
Melanoma Cells ◽  
Fast Neutrons

scholarly journals Toxicogenomics of A375 human malignant melanoma cells treated with arbutin

2006 ◽  
Vol 14 (1) ◽  
pp. 87-105 ◽  
Author(s):  
Sun-Long Cheng ◽  
Rosa Huang Liu ◽  
Jin-Nan Sheu ◽  
Shui-Tein Chen ◽  
Supachok Sinchaikul ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Melanoma Cells ◽  
Human Malignant Melanoma
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