scholarly journals Hormetic Response to Low-Dose Radiation: Focus on the Immune System and Its Clinical Implications

2017 ◽  
Vol 18 (2) ◽  
pp. 280 ◽  
Author(s):  
Jiuwei Cui ◽  
Guozi Yang ◽  
Zhenyu Pan ◽  
Yuguang Zhao ◽  
Xinyue Liang ◽  
...  
Keyword(s):  
Immune System ◽  
Low Dose ◽  
Clinical Implications ◽  
Low Dose Radiation ◽  
Hormetic Response ◽  
Dose Radiation

scholarly journals Effects of low dose radiation on immune cells subsets and cytokines in mice

2020 ◽  
Vol 9 (3) ◽  
pp. 249-262
Author(s):  
Xiaochang Liu ◽  
Zheng Liu ◽  
Duo Wang ◽  
Yang Han ◽  
Sai Hu ◽  
...  
Keyword(s):  
Immune System ◽  
Immune Cells ◽  
Low Dose ◽  
White Blood Cells ◽  
Whole Body ◽  
Low Dose Radiation ◽  
Dose Irradiation ◽  
Significant Difference ◽  
Dose Radiation

Abstract Whole-body exposure to low-dose radiation due to diagnostic imaging procedures, occupational hazards and radiation accidents is a source of concern. In this study, we analyzed the effects of single and long-term low-dose irradiation on the immune system. Male Balb/c mice received a single whole-body dose of irradiation (0.01, 0.05, 0.2, 0.5 or 1 Gy). For long-term irradiation, mice were irradiated 10 times (total dose of 0.2, 0.5 or 1 Gy) over a period of 6 weeks. Two days after single or long-term irradiation, the numbers of splenic macrophages, natural killer cells and dendritic cells were reduced, and the spleen organ coefficient was decreased. At 2 Days after long-term low-dose irradiation, the number of white blood cells in the peripheral blood of the mice decreased. Between 7 and 14 Days after long-term low-dose irradiation, the number of immune cells in the thymus and spleen began to increase and then stabilized. Th1/Th2 cytokines and reactive oxygen species-related proteins first decreased and then increased to a plateau. Our results show a significant difference in the effects of single and long-term low-dose irradiation on the immune system.

scholarly journals Validating the pivotal role of the immune system in low-dose radiation-induced tumor inhibition in Lewis lung cancer-bearing mice

2018 ◽  
Vol 7 (4) ◽  
pp. 1338-1348 ◽  
Author(s):  
Lei Zhou ◽  
Xiaoying Zhang ◽  
Hui Li ◽  
Chao Niu ◽  
Dehai Yu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Immune System ◽  
Low Dose ◽  
Lewis Lung ◽  
Low Dose Radiation ◽  
Lewis Lung Cancer ◽  
Tumor Inhibition ◽  
Radiation Induced ◽  
Dose Radiation

Effects of Low-Dose Radiation on the Immune System of Mice after Total-Body Irradiation

2010 ◽  
Vol 174 (4) ◽  
pp. 480-489 ◽  
Author(s):  
Enikő Noémi Bogdándi ◽  
Andrea Balogh ◽  
Nikolett Felgyinszki ◽  
Tünde Szatmári ◽  
Eszter Persa ◽  
...  
Keyword(s):  
Immune System ◽  
Total Body Irradiation ◽  
Low Dose ◽  
Low Dose Radiation ◽  
Total Body ◽  
Dose Radiation

scholarly journals A systematic review on the effect of low-dose radiation on hearing

2021 ◽  
Author(s):  
Srikanth Nayak ◽  
Arivudai Nambi ◽  
Sathish Kumar ◽  
P Hariprakash ◽  
Pradeep Yuvaraj ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Low Dose ◽  
Behavioral Symptoms ◽  
National Council ◽  
Low Dose Radiation ◽  
Cochlear Function ◽  
High Frequencies ◽  
Dose Radiation

AbstractNumerous studies have documented the adverse effects of high-dose radiation on hearing in patients. On the other hand, radiographers are exposed to a low dose of ionizing radiation, and the effect of a low dose of radiation on hearing is quite abstruse. Therefore, the present systematic review aimed to elucidate the effect of low-dose ionizing radiation on hearing. Two authors independently carried out a comprehensive data search in three electronic databases, including PUBMED/MEDLINE, CINAHL, and SCOPUS. Eligible articles were independently assessed for quality by two authors. Cochrane Risk of Bias tool was used assess quality of the included studies. Two articles met the low-dose radiation exposure criteria given by Atomic Energy Regulatory Board (AERB) and National Council on Radiation Protection (NCRP) guidelines. Both studies observed the behavioral symptoms, pure-tone hearing sensitivity at the standard, extended high frequencies, and the middle ear functioning in low-dose radiation-exposed individuals and compared with age and gender-matched controls. One study assessed the cochlear function using transient-evoked otoacoustic emissions (TEOAE). Both studies reported that behavioral symptoms of auditory dysfunction and hearing thresholds at extended high frequencies were higher in radiation-exposed individuals than in the controls. The current systematic review concludes that the low-dose ionizing radiation may affect the hearing adversely. Nevertheless, further studies with robust research design are required to explicate the cause and effect relationship between the occupational low-dose ionizing radiation exposure and hearing.

scholarly journals Double-layered fiber for lightweight flexible clothing providing shielding from low-dose natural radiation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seon-Chil Kim ◽  
Jun Sik Son
Keyword(s):  
Low Dose ◽  
Layered Composite ◽  
Radiation Shielding ◽  
Flight Attendants ◽  
Low Dose Radiation ◽  
Natural Radiation ◽  
Composite Yarn ◽  
Materials Used ◽  
Fiber Fabric ◽  
Dose Radiation

AbstractNatural and medical radiation are the most frequent sources of daily low-dose radiation exposure for the general public, but these radiation levels are generally acceptable. Among various occupations, aviation crew members and medical workers are exposed to high levels of radiation from scattered rays. This study focused on developing clothing for shielding aviation crew members from natural radiation during air travel. Materials were selected considering their radiation-shielding properties. A tungsten double-layered composite yarn and a polyethylene terephthalate (PET) fiber fabric containing BaSO4 were manufactured. The characteristics and shielding performances of the products were analyzed. Prototypes of a protective scarf (for shielding the thyroid gland) and apron (for shielding the torso) for flight attendants were produced. A lightweight fabric was produced that neither restricts the movement of the wearer nor causes them skin discomfort. The shielding performances of the tungsten composite and PET fiber fabrics containing BaSO4 were 0.018 mmPb and 0.03 mmPb, respectively, demonstrating low-dose shielding that may be useful for protecting aviation crew members from scattered rays. The characteristics of the developed fibers are comparable to those of materials used in clothing production; therefore, low-dose radiation-shielding clothing could be manufactured for use in aviation, medical, and other industries.

Sensitization of cervical cancer cell lines to low-dose radiation by retinoic acid does not require functional p53

2005 ◽  
Vol 97 (1) ◽  
pp. 142-150 ◽  
Author(s):  
Todd D. Tillmanns ◽  
Scott A. Kamelle ◽  
Suresh Guruswamy ◽  
Natalie S. Gould ◽  
Teresa L. Rutledge ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Retinoic Acid ◽  
Cell Lines ◽  
Cancer Cell ◽  
Low Dose ◽  
Cancer Cell Lines ◽  
Cervical Cancer Cell ◽  
Low Dose Radiation ◽  
Dose Radiation
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