Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma

Yuh Baba; Toyonobu Maeda; Atsuko Suzuki; Satoshi Takada; Masato Fujii; Yasumasa Kato

doi:10.3390/ijms18020262

Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma

International Journal of Molecular Sciences ◽

10.3390/ijms18020262 ◽

2017 ◽

Vol 18 (2) ◽

pp. 262 ◽

Cited By ~ 4

Author(s):

Yuh Baba ◽

Toyonobu Maeda ◽

Atsuko Suzuki ◽

Satoshi Takada ◽

Masato Fujii ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Neck Squamous Cell Carcinoma ◽

Egfr Tyrosine Kinase Inhibitor ◽

Apoptotic Activity

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Acquired resistance to EGFR tyrosine kinase inhibitor in A431 squamous cell carcinoma xenografts is mediated by c-Kit pathway transduction

Tumor Biology ◽

10.1007/s13277-014-2932-7 ◽

2014 ◽

Vol 36 (4) ◽

pp. 2993-2999 ◽

Cited By ~ 3

Author(s):

Lixia Zhang ◽

Xiaokun Yang ◽

Bei Zhao ◽

Zhen Cai

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase Inhibitor ◽

Egfr Tyrosine Kinase

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Transformation to a squamous cell carcinoma phenotype of an EGFR-mutated NSCLC patient after treatment with an EGFR-tyrosine kinase inhibitor

Journal of Clinical Pathology ◽

10.1136/jclinpath-2015-202866 ◽

2015 ◽

Vol 68 (4) ◽

pp. 320-321 ◽

Cited By ~ 26

Author(s):

Justine L Kuiper ◽

Merle I Ronden ◽

Annemarie Becker ◽

Daniëlle A M Heideman ◽

Peter van Hengel ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Nsclc Patient ◽

Egfr Tyrosine Kinase Inhibitor ◽

Egfr Tyrosine Kinase ◽

Egfr Mutated

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Targeted molecular therapy of head and neck squamous cell carcinoma with the tyrosine kinase inhibitor vandetanib in a mouse model

Head & Neck ◽

10.1002/hed.21455 ◽

2010 ◽

pp. n/a-n/a ◽

Cited By ~ 5

Author(s):

Daisuke Sano ◽

David R. Fooshee ◽

Mei Zhao ◽

Genevieve A. Andrews ◽

Mitchell J. Frederick ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Mouse Model ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Molecular Therapy ◽

Targeted Molecular Therapy

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Efficacy and Toxicity of Tyrosine Kinase Inhibitor Along with Platinum Based Concurrent Chemoirradiation In Locally Advanced Squamous Cell Carcinoma of Head And Neck

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2010.07.271 ◽

2010 ◽

Vol 78 (3) ◽

pp. S105 ◽

Cited By ~ 1

Author(s):

P.K. Nandwani ◽

R. Vyas ◽

M. Mehta ◽

J. Neema

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Locally Advanced ◽

Advanced Squamous Cell Carcinoma

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Abstract CT229: A phase II and biomarker study of an irreversible pan-human EGF receptor (HER) tyrosine kinase inhibitor, dacomitinib, in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck (R/M-SCCHN)

10.1158/1538-7445.am2014-ct229 ◽

2014 ◽

Author(s):

Han Sang Kim ◽

Hyung Joo Kwon ◽

Myung-Ju Ahn ◽

Byung Woog Kang ◽

Jong-Mu Sun ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Head And Neck ◽

Phase Ii ◽

Squamous Cell ◽

Egf Receptor ◽

Kinase Inhibitor ◽

Metastatic Squamous Cell Carcinoma

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Phase II study of oral lapatinib, a dual-tyrosine kinase inhibitor, combined with chemoradiotherapy (CRT) in patients (pts) with locally advanced, unresected squamous cell carcinoma of the head and neck (SCCHN).

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.5505 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 5505-5505 ◽

Cited By ~ 13

Author(s):

K. J. Harrington ◽

A. Berrier ◽

M. Robinson ◽

E. Remenar ◽

M. Housset ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Head And Neck ◽

Phase Ii ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Phase Ii Study ◽

Locally Advanced

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EGFR Tyrosine Kinase Inhibitor Pelitinib Regulates Radiation-Induced p65-Dependent Telomerase Activation in Squamous Cell Carcinoma

Radiation Research ◽

10.1667/rr3028.1 ◽

2013 ◽

Vol 179 (3) ◽

pp. 304-312 ◽

Cited By ~ 5

Author(s):

Natarajan Aravindan ◽

Sheeja Aravindan ◽

Terence S. Herman ◽

Mohan Natarajan

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Egfr Tyrosine Kinase Inhibitor ◽

Egfr Tyrosine Kinase ◽

Radiation Induced

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EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5.

International Journal of Oncology ◽

10.3892/ijo.13.2.335 ◽

1998 ◽

Author(s):

H Modjtahedi ◽

K Affleck ◽

C Stubberfield ◽

C Dean

Keyword(s):

Monoclonal Antibody ◽

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Kinase Inhibitor ◽

Terminal Differentiation ◽

Human Squamous Cell Carcinoma

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Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-18-1274 ◽

2019 ◽

Vol 19 (2) ◽

pp. 614-626 ◽

Cited By ~ 1

Author(s):

Lluís Nisa ◽

Paola Francica ◽

Roland Giger ◽

Matúš Medo ◽

Olgun Elicin ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Receptor Tyrosine Kinase ◽

Neck Squamous Cell Carcinoma ◽

Advanced Head ◽

Met Receptor ◽

Met Receptor Tyrosine Kinase

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Tyrosine kinase inhibitors in head and neck squamous cell carcinoma – a therapeutic chance?

10.1055/s-0041-1727986 ◽

2021 ◽

Author(s):

A Lammert ◽

A Affolter ◽

J Heid ◽

Y Jakob ◽

F Jungbauer ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Tyrosine Kinase ◽

Cell Carcinoma ◽

Head And Neck ◽

Tyrosine Kinase Inhibitors ◽

Squamous Cell ◽

Kinase Inhibitors ◽

Neck Squamous Cell Carcinoma

Download Full-text