scholarly journals Identification, Molecular Cloning of IL-1β and Its Expression Profile during Nocardia seriolae Infection in Largemouth Bass, Micropterus salmoides

2016 ◽  
Vol 17 (10) ◽  
pp. 1670 ◽  
Author(s):  
Ping-Yueh Ho ◽  
Omkar Byadgi ◽  
Pei-Chyi Wang ◽  
Ming-An Tsai ◽  
Li-Ling Liaw ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Expression Profile ◽  
Largemouth Bass ◽  
Micropterus Salmoides ◽  
Nocardia Seriolae

Immune response of largemouth bass, Micropterus salmoides, to whole cells of different Nocardia seriolae strains

2010 ◽  
Vol 76 (3) ◽  
pp. 489-494 ◽  
Author(s):  
Yoshiko Shimahara ◽  
Yun-Fen Huang ◽  
Ming-An Tsai ◽  
Pei-Chi Wang ◽  
Shih-Chu Chen
Keyword(s):  
Immune Response ◽  
Largemouth Bass ◽  
Micropterus Salmoides ◽  
Whole Cells ◽  
Nocardia Seriolae

scholarly journals Interleukin 34 Serves as a Novel Molecular Adjuvant against Nocardia Seriolae Infection in Largemouth Bass (Micropterus Salmoides)

Vaccines ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 151
Author(s):  
Huy Hoa Hoang ◽  
Pei-Chi Wang ◽  
Shih-Chu Chen
Keyword(s):  
Dna Vaccine ◽  
Largemouth Bass ◽  
Teleost Fish ◽  
Bacterial Infections ◽  
Micropterus Salmoides ◽  
Cell Mediated Immunity ◽  
Molecular Adjuvant ◽  
Genes Encoding ◽  
Immune Related Genes ◽  
Nocardia Seriolae

DNA vaccines have been widely employed in controlling viral and bacterial infections in mammals and teleost fish. Co-injection of molecular adjuvants, including chemokines, cytokines, and immune co-stimulatory molecules, is one of the potential strategies used to improve DNA vaccine efficacy. In mammals and teleost fish, interleukin-34 (IL-34) had been described as a multifunctional cytokine and its immunological role had been confirmed; however, the adjuvant capacity of IL-34 remains to be elucidated. In this study, IL-34 was identified in largemouth bass. A recombinant plasmid of IL-34 (pcIL-34) was constructed and co-administered with a DNA vaccine encoding hypoxic response protein 1 (Hrp1; pcHrp1) to evaluate the adjuvant capacity of pcIL-34 against Nocardia seriolae infection. Our results indicated that pcIL-34 co-injected with pcHrp1 not only triggered innate immunity and a specific antibody response, but also enhanced the mRNA expression level of immune-related genes encoding for cytokines, chemokines, and humoral and cell-mediated immunity. Moreover, pcIL-34 enhanced the protection of pcHrp1 against N. seriolae challenge and conferred the relative percent survival of 82.14%. Collectively, IL-34 is a promising adjuvant in a DNA vaccine against nocardiosis in fish.

Molecular characterization and biological function of CXCR1 in Nocardia seriolae-infected largemouth bass (Micropterus salmoides)

2021 ◽  
Vol 72 ◽  
pp. 101551
Author(s):  
Jiaqian Feng ◽  
Tao Han ◽  
Yuexing Zhang ◽  
Bing Zhang ◽  
Dexiang Huang ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Largemouth Bass ◽  
Biological Function ◽  
Micropterus Salmoides ◽  
Nocardia Seriolae
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