scholarly journals Role of Lipids in the Onset, Progression and Treatment of Periodontal Disease. A Systematic Review of Studies in Humans

2016 ◽  
Vol 17 (8) ◽  
pp. 1202 ◽  
Author(s):  
Alfonso Varela-López ◽  
Francesca Giampieri ◽  
Pedro Bullón ◽  
Maurizio Battino ◽  
José Quiles
Keyword(s):  
Systematic Review ◽  
Periodontal Disease

scholarly journals The role of probiotic bacteria in managing periodontal disease: a systematic review

2016 ◽  
Vol 14 (7) ◽  
pp. 643-655 ◽  
Author(s):  
Victor Haruo Matsubara ◽  
H. M. H. N. Bandara ◽  
Karin Hitomi Ishikawa ◽  
Marcia Pinto Alves Mayer ◽  
Lakshman Perera Samaranayake
Keyword(s):  
Systematic Review ◽  
Periodontal Disease ◽  
Probiotic Bacteria

scholarly journals Expression of MicroRNAs in Periodontal Disease: A Systematic Review

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
María Verónica Cuevas-González ◽  
Fernando Suaste-Olmos ◽  
Alma Graciela García-Calderón ◽  
Karla Lizette Tovar-Carrillo ◽  
León Francisco Espinosa-Cristóbal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Soft Tissues ◽  
Regulation Of Gene Expression ◽  
Gingival Tissue ◽  
Main Technique ◽  
Size Type ◽  
Gingival Fluid

Introduction. Periodontal disease (PD) is a chronic inflammation of the soft tissues that support the structure of the tooth, and miRNAs are highly dynamic molecules that participate in the regulation of gene expression interfering with multiple genetic targets. The dysregulation of the expression of miRNAs has been associated with different types of pathologies; therefore, they are excellent molecules to be studied as biomarkers. Material and Methods. A search was made in the electronic databases of PubMed, Scopus, and Science Direct. The following key words were used: “microRNAs,” “miRNAs,” “periodontal disease,” “periodontitis,” and “biomarker”; employee independent search strategies with the Boolean operators “OR” and “AND”; a further search of the references of the selected studies was performed to detect potential studies that met the selection criteria. The data recollected from each article were author, country, year of publication, sample size, type of sample used to identify miRNAs, methodology used to identify miRNAs, type of periodontal disease, and miRNAs identified. Results. Of the 13 selected studies, 6 used gingival tissue as a sample for the identification of miRNAs, 3 used gingival fluid, 2 used saliva, 1 used serum, and another used periodontal tissue. Chronic periodontitis was the most studied periodontal disease in 9 of the 13 selected articles; 7 used microarrays as the main technique for the identification of miRNAs. qRT-PCR was the assay choice to validate the identified miRNAs. Conclusion. The main type of periodontal disease on which most studies are focused is chronic periodontitis, with the main miRNAs being hsa-miR-146a, hsa-miR-146b, hsa-miR-155, and hsa-miR-200. This systematic review is one of the first to carry out an analysis of the current role of miRNAs in PD as biomarkers.

scholarly journals The Role of DNA Methylation and Histone Modification in Periodontal Disease: A Systematic Review

2020 ◽  
Vol 21 (17) ◽  
pp. 6217
Author(s):  
Ismael Khouly ◽  
Rosalie Salus Braun ◽  
Michelle Ordway ◽  
Bradley Eric Aouizerat ◽  
Iya Ghassib ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dna Methylation ◽  
Periodontal Disease ◽  
Histone Modification ◽  
Histone Modifications ◽  
Disease Risk ◽  
Periodontal Diseases ◽  
Epigenetic Changes ◽  
Human Adults

Despite a number of reports in the literature on the role of epigenetic mechanisms in periodontal disease, a thorough assessment of the published studies is warranted to better comprehend the evidence on the relationship between epigenetic changes and periodontal disease and its treatment. Therefore, the aim of this systematic review is to identify and synthesize the evidence for an association between DNA methylation/histone modification and periodontal disease and its treatment in human adults. A systematic search was independently conducted to identify articles meeting the inclusion criteria. DNA methylation and histone modifications associated with periodontal diseases, gene expression, epigenetic changes after periodontal therapy, and the association between epigenetics and clinical parameters were evaluated. Sixteen studies were identified. All included studies examined DNA modifications in relation to periodontitis, and none of the studies examined histone modifications. Substantial variation regarding the reporting of sample sizes and patient characteristics, statistical analyses, and methodology, was found. There was some evidence, albeit inconsistent, for an association between DNA methylation and periodontal disease. IL6, IL6R, IFNG, PTGS2, SOCS1, and TNF were identified as candidate genes that have been assessed for DNA methylation in periodontitis. While several included studies found associations between methylation levels and periodontal disease risk, there is insufficient evidence to support or refute an association between DNA methylation and periodontal disease/therapy in human adults. Further research must be conducted to identify reproducible epigenetic markers and determine the extent to which DNA methylation can be applied as a clinical biomarker.

scholarly journals Role of melatonin in periodontal disease - A systematic review

2020 ◽  
Vol 31 (4) ◽  
pp. 593
Author(s):  
SSwarna Meenakshi ◽  
Sankari Malaiappan
Keyword(s):  
Systematic Review ◽  
Periodontal Disease

A literature review on firms' internationalisation through e-commerce

2019 ◽  
pp. 121-143
Author(s):  
Riccardo Resciniti ◽  
Federica De Vanna
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
International Business ◽  
Decision Process ◽  
Foreign Markets ◽  
New Markets ◽  
Integrative Framework ◽  
The Past ◽  
The Relationship

The rise of e-commerce has brought considerable changes to the relationship between firms and consumers, especially within international business. Hence, understanding the use of such means for entering foreign markets has become critical for companies. However, the research on this issue is new and so it is important to evaluate what has been studied in the past. In this study, we conduct a systematic review of e-commerce and internationalisation studies to explicate how firms use e-commerce to enter new markets and to export. The studies are classified by theories and methods used in the literature. Moreover, we draw upon the internationalisation decision process (antecedents-modalities-consequences) to propose an integrative framework for understanding the role of e-commerce in internationalisation

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