scholarly journals Adverse Biological Effect of TiO2 and Hydroxyapatite Nanoparticles Used in Bone Repair and Replacement

2016 ◽  
Vol 17 (6) ◽  
pp. 798 ◽  
Author(s):  
Jiangxue Wang ◽  
Liting Wang ◽  
Yubo Fan
Keyword(s):  
Biological Effect ◽  
Bone Repair ◽  
Hydroxyapatite Nanoparticles ◽  
Adverse Biological Effect

scholarly journals DeepSIBA: chemical structure-based inference of biological alterations using deep learning

2021 ◽  
Author(s):  
C. Fotis ◽  
N. Meimetis ◽  
A. Sardis ◽  
L. G. Alexopoulos
Keyword(s):  
Deep Learning ◽  
Drug Discovery ◽  
In Silico ◽  
Biological Effect ◽  
Chemical Structure ◽  
Adverse Biological Effect

Predicting whether a chemical structure leads to a desired or adverse biological effect can have a significant impact for in silico drug discovery.

Surface-enrichment with hydroxyapatite nanoparticles in stereolithography-fabricated composite polymer scaffolds promotes bone repair

2017 ◽  
Vol 54 ◽  
pp. 386-398 ◽  
Author(s):  
O. Guillaume ◽  
M.A. Geven ◽  
C.M. Sprecher ◽  
V.A. Stadelmann ◽  
D.W. Grijpma ◽  
...  
Keyword(s):  
Bone Repair ◽  
Polymer Scaffolds ◽  
Hydroxyapatite Nanoparticles ◽  
Surface Enrichment ◽  
Composite Polymer

SOME ASPECTS OF THE FUNCTION OF FSH- AND LH-LIKE HORMONES IN NORMAL AND HYPOPHYSECTOMIZED FEMALE RATS, IN CONNECTION WITH RESERPINE ADMINISTRATION

1965 ◽  
Vol 49 (1) ◽  
pp. 28-38
Author(s):  
M. Grönroos ◽  
E. Mäkinen ◽  
K. Lahtinen ◽  
R. Tirri
Keyword(s):  
Mechanism Of Action ◽  
Biological Effect ◽  
Female Rats ◽  
Histological Picture ◽  
Peripheral Effect ◽  
Pituitary Secretion

ABSTRACT The effect of reserpine on the secretion of FSH and LH was studied as well as the role of the peripheral effect of reserpine after hypophysectomy. The results in the unoperated animals suggest that reserpine inhibits the pituitary secretion of both FSH and LH. Both these hormones combined with reserpine had a very different biological effect than was seen without reserpine. HCG (LH-like) and particularly PMS (FSH-like) hormones combined with reserpine caused definite enlargement of the ovaries. In the hypophysectomized groups, the effect of the PMS and HCG hormones administered together with reserpine or without it was the same with regard to the weight of the ovaries, but not with regard to their histological picture. On the basis of these results, reserpine may be said to have a peripheral effect although the nature of its mechanism of action is difficult to state. Reserpine probably affects the ovaries by inhibiting the follicular cycle and, consequently, the formation of new and more mature follicles.

Bone repair in orthotopic allo-and xeno-transplantation

2019 ◽  
Vol 17 (1) ◽  
pp. 80-81
Author(s):  
T. A. Silanteva ◽  
◽  
A. N. Nakoskin ◽  
N. V. Nakoskina ◽  
I. A. Talashova ◽  
...  
Keyword(s):  
Bone Repair
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