scholarly journals The mRNA Expression Status of Dopamine Receptor D2, Dopamine Receptor D3 and DARPP-32 in T Lymphocytes of Patients with Early Psychosis

2015 ◽  
Vol 16 (11) ◽  
pp. 26677-26686 ◽  
Author(s):  
Yin Cui ◽  
Vishwanath Prabhu ◽  
Thong Nguyen ◽  
Binod Yadav ◽  
Young-Chul Chung
Keyword(s):  
T Lymphocytes ◽  
Mrna Expression ◽  
Dopamine Receptor ◽  
Early Psychosis ◽  
D2 Dopamine Receptor ◽  
Dopamine Receptor D2 ◽  
Expression Status

Developmental prefrontal mRNA expression of D2 dopamine receptor splice variants and working memory impairments in rats after early life Interleukin-1β elevation

2018 ◽  
Vol 155 ◽  
pp. 231-238
Author(s):  
Alexander P. Schwarz ◽  
Alexander Yu. Rotov ◽  
Olga I. Chuprina ◽  
Darya U. Krytskaya ◽  
Alexander N. Trofimov ◽  
...  
Keyword(s):  
Working Memory ◽  
Mrna Expression ◽  
Dopamine Receptor ◽  
Early Life ◽  
Splice Variants ◽  
Interleukin 1Β ◽  
D2 Dopamine Receptor ◽  
Memory Impairments

Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice

2000 ◽  
Vol 80 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Kuei Y Tseng ◽  
Christine Roubert ◽  
Louis Do ◽  
Marcelo Rubinstein ◽  
Michele A Kelly ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Dopamine Receptor ◽  
Dopaminergic Neurons ◽  
D2 Dopamine Receptor ◽  
Selective Increase ◽  
Deficient Mice

Prefrontal mRNA expression of long and short isoforms of D2 dopamine receptor: Possible role in delayed learning deficit caused by early life interleukin-1β treatment

2017 ◽  
Vol 333 ◽  
pp. 118-122 ◽  
Author(s):  
Alexander P. Schwarz ◽  
Alexander N. Trofimov ◽  
Olga E. Zubareva ◽  
Victoria I. Lioudyno ◽  
Vera V. Kosheverova ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Dopamine Receptor ◽  
Early Life ◽  
Interleukin 1Β ◽  
D2 Dopamine Receptor ◽  
Learning Deficit ◽  
Short Isoforms

scholarly journals Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms

Biomolecules ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1355
Author(s):  
Kaja Blagotinšek Cokan ◽  
Maša Mavri ◽  
Catrin Sian Rutland ◽  
Sanja Glišić ◽  
Milan Senćanski ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
Intracellular Localization ◽  
Interacting Proteins ◽  
D2 Dopamine Receptor ◽  
Dopamine Receptor D2 ◽  
Evolutionarily Conserved ◽  
Interaction Partners ◽  
Receptor Interacting Proteins ◽  
G Protein Coupled

The type 2 dopamine receptor D2 (D2-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D2S-R) and long (D2L-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the D2L-R. These isoforms differ in their intracellular localization and trafficking functionality, as D2L-R possesses a larger intracellular pool, mostly in the endoplasmic reticulum (ER). This review focuses on the evolutionarily conserved motifs in the ICL3 of the D2-R and proteins interacting with the ICL3 of both isoforms, specifically with the 29 AA insert. These motifs might be involved in D2-R exit from the ER and have an impact on cell-surface and intracellular localization and, therefore, also play a role in the function of dopamine receptor signaling, ligand binding and possible homo/heterodimerization. Our recent bioinformatic data on potential new interaction partners for the ICL3 of D2-Rs are also presented. Both are highly relevant, and have clinical impacts on the pathophysiology of several diseases such as Parkinson’s disease, schizophrenia, Tourette’s syndrome, Huntington’s disease, manic depression, and others, as they are connected to a variety of essential motifs and differences in communication with interaction partners.

Role of trace amine associated receptor 1 (TAAR1) in D2 dopamine receptor-related behavior and signaling

2012 ◽  
Author(s):  
S. Espinoza ◽  
F. Manago ◽  
M. Messa ◽  
T. D. Sotnikova ◽  
M. Caron ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
D2 Dopamine Receptor ◽  
Trace Amine

Role of Trace Amine Associated Receptor 1 (TAAR1) in D2 Dopamine receptor-related behavior and signaling

2012 ◽  
Author(s):  
S. Espinoza ◽  
F. Manago ◽  
M. Messa ◽  
T. D. Sotnikova ◽  
M. Caron ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
D2 Dopamine Receptor ◽  
Trace Amine
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