scholarly journals Comparison of Metabolite Concentrations in the Left Dorsolateral Prefrontal Cortex, the Left Frontal White Matter, and the Left Hippocampus in Patients in Stable Schizophrenia Treated with Antipsychotics with or without Antidepressants. 1H-NMR Spectroscopy Study

2015 ◽  
Vol 16 (10) ◽  
pp. 24387-24402 ◽  
Author(s):  
Dominik Strzelecki ◽  
Piotr Grzelak ◽  
Michał Podgórski ◽  
Olga Kałużyńska ◽  
Ludomir Stefańczyk ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
White Matter ◽  
Nmr Spectroscopy ◽  
1H Nmr Spectroscopy ◽  
Dorsolateral Prefrontal Cortex ◽  
Spectroscopy Study ◽  
Left Hippocampus ◽  
Frontal White Matter ◽  
Metabolite Concentrations ◽  
Dorsolateral Prefrontal

Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients

2005 ◽  
Vol 384 (3) ◽  
pp. 321-326 ◽  
Author(s):  
Sheila C. Caetano ◽  
Manoela Fonseca ◽  
Rene L. Olvera ◽  
Mark Nicoletti ◽  
John P. Hatch ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Dorsolateral Prefrontal Cortex ◽  
Spectroscopy Study ◽  
Proton Spectroscopy ◽  
Depressed Patients ◽  
Dorsolateral Prefrontal

scholarly journals No preliminary evidence of differences in astrocyte density within the white matter of the dorsolateral prefrontal cortex in autism

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Ting Ting Lee ◽  
Efstratios Skafidas ◽  
Mirella Dottori ◽  
Daniela Zantomio ◽  
Christos Pantelis ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
White Matter ◽  
Dorsolateral Prefrontal Cortex ◽  
Preliminary Evidence ◽  
Dorsolateral Prefrontal

scholarly journals Increased Interstitial White Matter Neuron Density in the Dorsolateral Prefrontal Cortex of People with Schizophrenia

2011 ◽  
Vol 69 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Yang Yang ◽  
Samantha J. Fung ◽  
Alice Rothwell ◽  
Si Tianmei ◽  
Cynthia Shannon Weickert
Keyword(s):  
Prefrontal Cortex ◽  
White Matter ◽  
Dorsolateral Prefrontal Cortex ◽  
Neuron Density ◽  
Dorsolateral Prefrontal

Does brain creatine content rely on exogenous creatine in healthy youth? A proof-of-principle study

2017 ◽  
Vol 42 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Carlos Alberto Abujabra Merege-Filho ◽  
Maria Concepción Garcia Otaduy ◽  
Ana Lúcia de Sá-Pinto ◽  
Maira Okada de Oliveira ◽  
Lívia de Souza Gonçalves ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Cognitive Performance ◽  
Dorsolateral Prefrontal Cortex ◽  
Verbal Learning ◽  
Creatine Supplementation ◽  
Occipital Lobe ◽  
Resonance Spectroscopy ◽  
Left Hippocampus ◽  
Dorsolateral Prefrontal ◽  
Proof Of Principle

It has been hypothesized that dietary creatine could influence cognitive performance by increasing brain creatine in developing individuals. This double-blind, randomized, placebo-controlled, proof-of-principle study aimed to investigate the effects of creatine supplementation on cognitive function and brain creatine content in healthy youth. The sample comprised 67 healthy participants aged 10 to 12 years. The participants were given creatine or placebo supplementation for 7 days. At baseline and after the intervention, participants undertook a battery of cognitive tests. In a random subsample of participants, brain creatine content was also assessed in the regions of left dorsolateral prefrontal cortex, left hippocampus, and occipital lobe by proton magnetic resonance spectroscopy (1H-MRS) technique. The scores obtained from verbal learning and executive functions tests did not significantly differ between groups at baseline or after the intervention (all p > 0.05). Creatine content was not significantly different between groups in left dorsolateral prefrontal cortex, left hippocampus, and occipital lobe (all p > 0.05). In conclusion, a 7-day creatine supplementation protocol did not elicit improvements in brain creatine content or cognitive performance in healthy youth, suggesting that this population mainly relies on brain creatine synthesis rather than exogenous creatine intake to maintain brain creatine homeostasis.

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