scholarly journals 8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells

2015 ◽  
Vol 16 (12) ◽  
pp. 14979-14996 ◽  
Author(s):  
Cui Zhang ◽  
Yingnan Jiang ◽  
Jin Zhang ◽  
Jian Huang ◽  
Jinhui Wang
Keyword(s):  
Cervical Cancer ◽  
Cell Death ◽  
Hela Cells ◽  
Human Cervical Cancer

scholarly journals Bersaldegenin-1,3,5-orthoacetate induces caspase-independent cell death, DNA damage and cell cycle arrest in human cervical cancer HeLa cells

2021 ◽  
Vol 59 (1) ◽  
pp. 54-65
Author(s):  
Justyna Stefanowicz-Hajduk ◽  
Magdalena Gucwa ◽  
Barbara Moniuszko-Szajwaj ◽  
Anna Stochmal ◽  
Anna Kawiak ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Dna Damage ◽  
Cell Death ◽  
Cell Cycle Arrest ◽  
Hela Cells ◽  
Cycle Arrest ◽  
Human Cervical Cancer

scholarly journals Metformin and arsenic trioxide synergize to trigger Parkin/pink1-dependent mitophagic cell death in human cervical cancer HeLa cells

2021 ◽  
Vol 12 (21) ◽  
pp. 6310-6319
Author(s):  
Jing Chen ◽  
Cunmin Zhou ◽  
Juan Yi ◽  
Jingjing Sun ◽  
Bei Xie ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cell Death ◽  
Arsenic Trioxide ◽  
Hela Cells ◽  
Human Cervical Cancer

Identification of Chemo and Radio-resistant Sub-population of Stem Cells in Human Cervical Cancer HeLa Cells

2021 ◽  
pp. 1-27
Author(s):  
Nabil Mohie Abdel-Hamid ◽  
Moustafa Fathy ◽  
Chika Koike ◽  
Toshiko Yoshida ◽  
Motonori Okabe ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Stem Cells ◽  
Hela Cells ◽  
Human Cervical Cancer

scholarly journals The Inhibitory Effect of a Novel Polypeptide Fraction fromArca subcrenataon Cancer-Related Inflammation in Human Cervical Cancer HeLa Cells

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Yu Wu ◽  
Xianjing Hu ◽  
Liyan Song ◽  
Jianhua Zhu ◽  
Rongmin Yu
Keyword(s):  
Cervical Cancer ◽  
Hela Cells ◽  
Molecular Mechanisms ◽  
Tumor Development ◽  
Basic Research ◽  
Inhibitory Effect ◽  
Fishery Resource ◽  
Proinflammatory Mediators ◽  
Raw264.7 Macrophage ◽  
Human Cervical Cancer

Inflammation is known to be closely associated with the development of cancer. The study was launched in human cervical cancer HeLa cells to investigate the antitumor and anti-inflammatory effects of P2, a marine polypeptide fraction from an important fishery resourceArca subcrenata. The basic research showed that P2 could suppress the production of nitric oxide in LPS-induced RAW264.7 macrophage cells as well as the secretion of inflammatory cytokines IL-6 and TNF-αin human cervical cancer HeLa cells. For the molecular mechanisms, P2 was shown to downregulate the gene expression of proinflammatory cytokines IL-6 and IL-8 and to inhibit the COX-2 and iNOS-related pathways in HeLa cells. In consequence, P2 might inhibit tumor development by blocking the interaction between tumor microenvironment and proinflammatory mediators. All findings indicate that P2 possesses the potential to be developed as a novel agent for cancer therapy.

scholarly journals Syringin exhibits anticancer effects in HeLa human cervical cancer cells by inducing apoptosis, cell cycle arrest and inhibition of cell migration

2016 ◽  
Vol 11 (4) ◽  
pp. 838 ◽  
Author(s):  
Ning Xia
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Cell Migration ◽  
Cell Cycle Arrest ◽  
Hela Cells ◽  
Dependent Manner ◽  
Cycle Arrest ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

<p class="Abstract">The present study was aimed at to demonstrate the antitumor effects of syringin in HeLa human cervical cancer cells. Its effects on apoptosis, cell cycle phase distribution as well as on cell migration were also examined. The effect on cell proliferation was evaluated by MTT assay, while as effects on colony formation were assessed using clonogenic assay. Syringin inhibited cancer cell growth in HeLa cells in a time-dependent as well as in a concentration-dependent manner. Syringin also led to inhibition of colony formation efficacy with complete suppression at 100 µM drug dose. Syringin could induce G2/M cell cycle arrest along with slight sub-G1 cell cycle arrest. HeLa cells began to emit red fluorescence as the dose of syringin increased from 0 µM in vehicle control to 100 µM. Syringin also inhibited cell migration in a dose-dependent manner with 100 µM dose of syringin leading to 100% inhibition of cell migration.</p><p> </p>

Cytotoxic activity of Rauvolfia tetraphylla L. on human cervical cancer (HeLa) cells

2019 ◽  
Vol 15 (65) ◽  
pp. 631 ◽  
Author(s):  
MaríaElena Sánchez-Mendoza ◽  
JoséAngel Santiago-Cruz ◽  
Jesús Arrieta ◽  
Jazmín García-Machorro ◽  
Daniel Arrieta-Baez
Keyword(s):  
Cervical Cancer ◽  
Cytotoxic Activity ◽  
Hela Cells ◽  
Rauvolfia Tetraphylla ◽  
Human Cervical Cancer

scholarly journals Caspase-Independent Cell Death by Arsenic Trioxide in Human Cervical Cancer Cells

2004 ◽  
Vol 64 (24) ◽  
pp. 8960-8967 ◽  
Author(s):  
Young-Hee Kang ◽  
Min-Jung Yi ◽  
Min-Jung Kim ◽  
Moon-Taek Park ◽  
Sangwoo Bae ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Arsenic Trioxide ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer
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