scholarly journals In Vitro Binding Capacity of Bile Acids by Defatted Corn Protein Hydrolysate

2011 ◽  
Vol 12 (2) ◽  
pp. 1066-1080 ◽  
Author(s):  
Jauricque Ursulla Kongo-Dia-Moukala ◽  
Hui Zhang ◽  
Pierre Claver Irakoze
Keyword(s):  
Bile Acids ◽  
Protein Hydrolysate ◽  
Binding Capacity ◽  
In Vitro Binding ◽  
Corn Protein ◽  
Vitro Binding

In vitro binding of bile acids by extruded potato peels

1993 ◽  
Vol 41 (12) ◽  
pp. 2391-2394 ◽  
Author(s):  
Mary E. Camire ◽  
Jianxin. Zhao ◽  
Dale A. Violette
Keyword(s):  
Bile Acids ◽  
In Vitro Binding ◽  
Vitro Binding ◽  
Potato Peels

scholarly journals In vitro binding of mutagenic heterocyclic aromatic amines by Bifidobacterium pseudocatenulatum G4

2010 ◽  
Vol 1 (2) ◽  
pp. 149-154 ◽  
Author(s):  
F. Faridnia ◽  
A. Hussin ◽  
N. Saari ◽  
S. Mustafa ◽  
L. Yee ◽  
...  
Keyword(s):  
High Performance ◽  
Binding Capacity ◽  
Bifidobacterium Longum ◽  
Heterocyclic Amines ◽  
Heterocyclic Aromatic Amines ◽  
Human Origin ◽  
Bacterial Strains ◽  
In Vitro Binding ◽  
Vitro Binding

Consumption of probiotics has been associated with decreased risk of colon cancer and reported to have antimutagenic/ anti-carcinogenic properties. One possible mechanism for this effect involves physical binding of the mutagenic compounds, such as heterocyclic amines (HCAs), to the bacteria. Therefore, the objective of this study was to examine the binding capacity of bifidobacterial strains of human origin on mutagenic heterocyclic amines which are suspected to play a role in human cancers. In vitro binding of the mutagens Trp-p-2, IQ, MeIQx, 7,8DiMeIQx and PhIP by three bacterial strains in two media of different pH was analysed using high performance liquid chromatography. Bifidobacterium pseudocatenulatum G4 showed the highest decrease in the total HCAs content, followed by Bifidobacterium longum, and Escherichia coli. pH affects binding capacity; the highest binding was obtained at pH 6.8. Gram-positive tested strains were found to be consistently more effective than the gram-negative strain. There were significant decreases in the amount of HCAs in the presence of different cell concentrations of B. pseudocatenulatum G4; the highest decrease was detected at the concentration of 1010 cfu/ml. The results showed that HCAs were able to bind with all bacterial strains tested in vitro, thus it may be possible to decrease their absorption by human intestine and increase their elimination via faeces.

Letter: In vitro binding of bile acids and bile salts

1975 ◽  
Vol 28 (4) ◽  
pp. 305-306 ◽  
Author(s):  
D Kritchevsky ◽  
J A Story
Keyword(s):  
Bile Acids ◽  
Bile Salts ◽  
In Vitro Binding ◽  
Vitro Binding
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