scholarly journals Köln-Timişoara Molecular Activity Combined Models toward Interspecies Toxicity Assessment

2009 ◽  
Vol 10 (10) ◽  
pp. 4474-4497 ◽  
Author(s):  
Sergiu Chicu ◽  
Mihai Putz
Keyword(s):  
Toxicity Assessment ◽  
Combined Models

Effect of carbofuran on quantitative and qualitative alterations in haemolymph of larva of Oryctes rhinoceros L. (Coleoptera: Scarabaeidae)

ENTOMON ◽  
2020 ◽  
Vol 44 (4) ◽  
pp. 293-300
Author(s):  
V.S. Salini
Keyword(s):  
Oral Route ◽  
Toxicity Assessment ◽  
Haematological Parameters ◽  
Oryctes Rhinoceros ◽  
Total Haemocyte Count ◽  
Differential Haemocyte Count ◽  
Third Instar Larvae

Investigation to evaluate the toxicity of carbofuran pesticides on haematological parameters of third instar larvae of Oryctes rhinoceros L. Indicated alterations in total haemocyte count and differential haemocyte count for toxicity assessment. Various doses of carbofuran (0.05g, 0.010g and 0.015 g) applied on insect through oral route and its impact after 24 hours of its application revealed that various doses of carbofuran exert specific alterations in both total and differential haemocytes of insect haemolymph.

Decolorization, Degradation and Subsequent Toxicity Assessment of Reactive Red 35 by Enterococcus gallinarum

2016 ◽  
Vol 5 (4) ◽  
pp. 325-336 ◽  
Author(s):  
Rakesh Soni ◽  
N.S. Bhatt ◽  
H.A. Modi ◽  
P.B. Acharya
Keyword(s):  
Toxicity Assessment ◽  
Enterococcus Gallinarum

Acute and Sub-acute Oral Toxicity Assessment of a Standardized Polyherbal Preparation POL-6 in Rats

2019 ◽  
Vol 9 (3) ◽  
pp. 207-216
Author(s):  
Lalit Sharma ◽  
Aditi Sharma ◽  
Girdhari L. Gupta ◽  
Gopal Singh Bisht
Keyword(s):  
Histopathological Examination ◽  
Safety Evaluation ◽  
Centella Asiatica ◽  
Toxicity Assessment ◽  
Ocimum Sanctum ◽  
Oral Toxicity ◽  
Significant Treatment ◽  
Body Weights ◽  
Total Body ◽  
Hematobiochemical Parameters

Background: A standardized polyherbal preparation (POL-6) containing six plant extracts Hypericum perforatum, Bacopa monnieri, Centella asiatica, Withania somnifera, Ocimum sanctum and Camellia sinesis have good antioxidant, anti-inflammatory, and immunomodulatory activities. The present study was carried out to evaluate the safety profile of POL-6 through acute and subacute oral toxicity models in Wistar rats. Methods: In acute safety evaluation, a single dose of 2000mg/kg of POL-6 was given orally to five rats and was observed for 14 days. In subacute safety evaluation POL-6 at the doses of 250, 500 and 1000 mg/kg was given orally to the rats once a day for 28 days. The animals were observed for the signs of toxicity and mortality during the study period. Results: In acute toxicity evaluation, POL-6 treatment did not show any toxic signs and mortality in animals during the observation period. In subacute toxicity studies, no changes were seen in any of the dose levels of POL-6 treatment during the total body weights, organ weights and hematobiochemical parameters examination of the rats. No lesions were seen during the gross/histopathological examination. Conclusion: The study revealed that administration of POL-6 for 28 days showed no significant treatment generated toxic effects in the animals, hence it can be considered as non-toxic if it is ingested in a time not greater than a month.

Acute Toxicity Assessment of Ethanolic Leaf Extract of Macrotyloma uniflorum L. on Wistar Albino Rats

2017 ◽  
Vol 24 (1) ◽  
pp. 22 ◽  
Author(s):  
S. Priyanga ◽  
S. Hemmalakshmi ◽  
B. Vidya ◽  
P. Chella Perumal ◽  
V. K. Gopalakrishnan ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Leaf Extract ◽  
Toxicity Assessment ◽  
Albino Rats ◽  
Macrotyloma Uniflorum ◽  
Wistar Albino Rats ◽  
Ethanolic Leaf Extract

An Approach to Acute, Subacute, Subchronic, and Chronic Toxicity Assessment in Animal Models

2015 ◽  
Vol 22 (2) ◽  
pp. 83
Author(s):  
Enegide Chinedu ◽  
David Arome ◽  
Fidelis Solomon Ameh ◽  
Dabum Luka Jacob
Keyword(s):  
Animal Models ◽  
Chronic Toxicity ◽  
Toxicity Assessment

scholarly journals Transformation of Contaminants of Emerging Concern (CECs) during UV-Catalyzed Processes Assisted by Chlorine

Catalysts ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1432
Author(s):  
Edyta Kudlek
Keyword(s):  
Hydrogen Peroxide ◽  
Water Samples ◽  
Water Environment ◽  
Toxicity Assessment ◽  
Contaminants Of Emerging Concern ◽  
Post Processing ◽  
Processing Water ◽  
Living Organisms ◽  
Trace Concentrations ◽  
By Products

Every compound that potentially can be harmful to the environment is called a Contaminant of Emerging Concern (CEC). Compounds classified as CECs may undergo different transformations, especially in the water environment. The intermediates formed in this way are considered to be toxic against living organisms even in trace concentrations. We attempted to identify the intermediates formed during single chlorination and UV-catalyzed processes supported by the action of chlorine and hydrogen peroxide or ozone of selected contaminants of emerging concern. The analysis of post-processing water samples containing benzocaine indicated the formation of seven compound intermediates, while ibuprofen, acridine and β-estradiol samples contained 5, 5, and 3 compound decomposition by-products, respectively. The number and also the concentration of the intermediates decreased with the time of UV irradiation. The toxicity assessment indicated that the UV-catalyzed processes lead to decreased toxicity nature of post-processed water solutions.

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