scholarly journals The Role of Vitamins in Oral Health. A Systematic Review and Meta-Analysis

2020 ◽  
Vol 17 (3) ◽  
pp. 938 ◽  
Author(s):  
Maria Grazia Cagetti ◽  
Thomas Gerhard Wolf ◽  
Christian Tennert ◽  
Nicole Camoni ◽  
Peter Lingström ◽  
...  
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Full Text ◽  
Ad Hoc ◽  
Evaluation Studies ◽  
Meta Analysis ◽  
Oral Diseases ◽  
Cross Sectional ◽  
Meta Analyses

The association between vitamins and oral health have recently been discussed, yielding increased attention from medical and dental perspectives. The present review aimed to systematically evaluate and appraise the most recently scientific papers investigating the role of vitamins in the prevention and treatment of the main oral diseases as hard dental pathological processes and gum/periodontal disease. Randomized controlled trials, cross-sectional studies, cohort studies, comparative studies, validation studies and evaluation studies, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, reporting associations between vitamins and oral diseases or the use of vitamins to prevent or treat oral diseases in patients of any age were included. PubMed, Embase and Scopus were searched to November 2019 using an ad hoc prepared search string. All the papers meeting the inclusion criteria were subjected to a quality assessment. The search identified 1597 papers; 741 were selected after removing duplicates. A total of 334 articles were excluded after title and abstract evaluation; 407 were assessed and 73 papers were full-text assessed; other 14 papers were discharged after full text evaluation, leaving finally 58 papers included. In general, there is weak evidence supporting the association between vitamins and both gingival/periodontal disease and hard dental pathological processes.

scholarly journals Oral health in children and adolescents with juvenile idiopathic arthritis – a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Marit S. Skeie ◽  
Elisabeth G. Gil ◽  
Lena Cetrelli ◽  
Annika Rosén ◽  
Johannes Fischer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Juvenile Idiopathic Arthritis ◽  
Oral Health ◽  
Children And Adolescents ◽  
Observational Studies ◽  
Meta Analysis ◽  
Oral Diseases ◽  
Cross Sectional ◽  
Healthy Group ◽  
Health Measures

Abstract Background Observational studies examining the association between oral health and juvenile idiopathic arthritis (JIA) among children and adolescents have reported inconsistent findings. The aims of this systematic review and meta-analysis were to ascertain a potential difference in oral health and oral health-related quality of life (OHRQoL) among children and adolescents with JIA and healthy peers, and to assess the association of prevalence of oral diseases/conditions, temporomandibular disorders (TMD), including temporomandibular joint (TMJ) diseases, in relation to activity and severity of JIA. Method Medline Ovid, Embase, CINAHL, SweMed+ and Cochrane Library were searched up to 25 November 2018. All articles published in English, German and Scandinavian languages focusing on children and adolescents with JIA and without JIA in relation to oral health measures, were considered. Two authors independently evaluated observational studies for inclusion. The study quality was assessed using modified Newcastle Ottawa Scale. Meta-analysis was performed for studies focusing on dental caries as an outcome. Results Nineteen articles met the inclusion criteria, covering a range of oral diseases/conditions and OHRQoL. Eighteen studies had cross-sectional design. No mean difference of dmft/DMFT indices (decayed/missed/filled teeth) was observed between the JIA - and healthy group. None of the oral health measures including dental erosive wear, enamel defects, dental maturation and OHRQoL, indicated better oral health among children and adolescents with JIA compared to healthy group. However, periodontal conditions and TMD were more predominant among children and adolescents with JIA compared to healthy peers. Conclusions Based on the cross-sectional studies, periodontal diseases and TMD were found to be more frequent in children and adolescents with JIA compared to healthy peers. Furthermore, more high-quality studies with large sample size are needed before we infer any concrete conclusion regarding the association between the prevalence of oral and TMJ diseases or oral conditions in relation to activity and severity of JIA.

scholarly journals Microbiota populations in supragingival plaque, subgingival plaque, and saliva habitats of adult dogs

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Patrícia M. Oba ◽  
Meredith Q. Carroll ◽  
Celeste Alexander ◽  
Helen Valentine ◽  
Amy J. Somrak ◽  
...  
Keyword(s):  
Oral Health ◽  
Oral Cavity ◽  
Periodontal Disease ◽  
Bacterial Species ◽  
Oral Disease ◽  
Oral Microbiota ◽  
Subgingival Plaque ◽  
Oral Diseases ◽  
Supragingival Plaque

Abstract Background Oral diseases are common in dogs, with microbiota playing a prominent role in the disease process. Oral cavity habitats harbor unique microbiota populations that have relevance to health and disease. Despite their importance, the canine oral cavity microbial habitats have been poorly studied. The objectives of this study were to (1) characterize the oral microbiota of different habitats of dogs and (2) correlate oral health scores with bacterial taxa and identify what sites may be good options for understanding the role of microbiota in oral diseases. We used next-generation sequencing to characterize the salivary (SAL), subgingival (SUB), and supragingival (SUP) microbial habitats of 26 healthy adult female Beagle dogs (4.0 ± 1.2 year old) and identify taxa associated with periodontal disease indices. Results Bacterial species richness was highest for SAL, moderate for SUB, and lowest for SUP samples (p < 0.001). Unweighted and weighted principal coordinates plots showed clustering by habitat, with SAL and SUP samples being the most different from one another. Bacteroidetes, Proteobacteria, Firmicutes, Fusobacteria, Actinobacteria, and Spirochaetes were the predominant phyla in all habitats. Paludibacter, Filifactor, Peptostreptococcus, Fusibacter, Anaerovorax, Fusobacterium, Leptotrichia, Desulfomicrobium, and TG5 were enriched in SUB samples, while Actinomyces, Corynebacterium, Leucobacter, Euzebya, Capnocytophaga, Bergeyella, Lautropia, Lampropedia, Desulfobulbus, Enhydrobacter, and Moraxella were enriched in SUP samples. Prevotella, SHD-231, Helcococcus, Treponema, and Acholeplasma were enriched in SAL samples. p-75-a5, Arcobacter, and Pasteurella were diminished in SUB samples. Porphyromonas, Peptococcus, Parvimonas, and Campylobacter were diminished in SUP samples, while Tannerella, Proteocalla, Schwartzia, and Neisseria were diminished in SAL samples. Actinomyces, Corynebacterium, Capnocytophaga, Leptotrichia, and Neisseria were associated with higher oral health scores (worsened health) in plaque samples. Conclusions Our results demonstrate the differences that exist among canine salivary, subgingival plaque and supragingival plaque habitats. Salivary samples do not require sedation and are easy to collect, but do not accurately represent the plaque populations that are most important to oral disease. Plaque Actinomyces, Corynebacterium, Capnocytophaga, Leptotrichia, and Neisseria were associated with higher (worse) oral health scores. Future studies analyzing samples from progressive disease stages are needed to validate these results and understand the role of bacteria in periodontal disease development.

scholarly journals To which extent are per-and poly-fluorinated substances associated to metabolic syndrome?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Maryam Zare Jeddi ◽  
Rozita Soltanmohammadi ◽  
Giulia Barbieri ◽  
Aline S. C. Fabricio ◽  
Gisella Pitter ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
General Population ◽  
Meta Analysis ◽  
Small Body ◽  
Epidemiological Studies ◽  
Cross Sectional ◽  
Random Effects Models ◽  
Epidemiologic Evidence ◽  
Adults And Children ◽  
Meta Analyses

Abstract Exposure to per- and polyfluoroalkyl substances (PFAS), ubiquitous persistent environmental contaminants, has led to substantial global concern due to their potential environmental and human health effects. Several epidemiological studies have assessed the possible association between PFAS exposure and risk of metabolic syndrome (MetS), however, the results are ambiguous. The aim of this study was to assess the current human epidemiologic evidence on the association between exposure to PFAS and MetS. We performed a systematic search strategy using three electronic databases (PubMed, Scopus, and Web of Science) for relevant studies concerning the associations of PFAS with MetS and its clinical relevance from inception until January 2021. We undertook meta-analyses where there were five or more studies with exposure and outcomes assessments that were reasonably comparable. The pooled odd ratios (ORs) were calculated using random effects models and heterogeneity among studies was assessed by I2 index and Q test. A total of 12 cross-sectional studies (10 studies on the general population and two studies in the occupational settings) investigated the association between PFAS exposure and MetS. We pooled data from seven studies on the general population for perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) and five studies for perfluorohexanesulfonate (PFHxS) and perfluorononanoic acid (PFNA). Predominately, most studies reported no statistically significant association between concentrations of PFAS and MetS. In the meta-analysis, the overall measure of effect was not statistically significant, showing no evidence of an association between concentrations of PFOA, PFOS, PFNA, and PFHxS and the risk of MetS. Based on the results of the meta-analysis, current small body of evidence does not support association between PFAS and MetS. However, due to limited number of studies and substantial heterogeneity, results should be interpreted with caution. Further scrutinizing cohort studies are needed to evaluate the association between various and less well-known PFAS substances and their mixture with MetS and its components in both adults and children in different settings.

scholarly journals 306 - Loneliness and mortality in older adults and the role of depression

2020 ◽  
Vol 32 (S1) ◽  
pp. 64-64
Author(s):  
T.J. Holwerda ◽  
D. Rhebergen ◽  
H.C. Comijs ◽  
J.J.M. Dekker ◽  
M.L. Stek
Keyword(s):  
Cardiovascular Disease ◽  
Older Adults ◽  
Mortality Risk ◽  
Meta Analysis ◽  
Clinical Perspective ◽  
Cross Sectional ◽  
Mediating Role ◽  
Underlying Mechanisms ◽  
Dexamethasone Suppression

Background:The prevalence of loneliness increases with age. The presence of loneliness in older adults has been found to be associated with health problems such as depression, decreased cognitive functioning, increases in systolic blood pressure and increased mortality. The underlying mechanisms of the higher mortality risk are largely unknown.Methods:Meta-analysis to investigate the present evidence for the associations between loneliness and mortality. Cross-sectional studies investigating the associations between loneliness and cardiovascular disease and between loneliness and cortisol in 378 depressed and 132 non-depressed older adults.Results:Loneliness appears to be associated with increased mortality, although when only studies are included that consider depression as a covariate, the association is not significant. Therefore it seems likely that depression plays a mediating role in the higher mortality risk.We did not find a significant association between loneliness and cardiovascular disease. In contrast, loneliness was significantly associated with lower cortisol output and decreased dexamethasone suppression.Discussion:The results and their implications for prevention and treatment will be discussed from a clinical perspective as well as a general health perspective. Is loneliness as potentially dangerous as depression?

scholarly journals Racial inequality and periodontal condition in Brazilian adolescents

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R S Moreira ◽  
L D R Santos
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Sex Education ◽  
Multinomial Logistic Regression ◽  
Permanent Teeth ◽  
Multiple Model ◽  
Oral Diseases ◽  
Socioeconomic Variables ◽  
Periodontal Index ◽  
Dmft Index

Abstract Background Oral health, such as other health conditions, reflects social inequalities. These inequalities are fed back by oral diseases, generating a vicious and sustainable circle. Racial issues play a prominent role, once they are associated with oral diseases as risk markers. Among the different oral diseases, periodontal disease associated with racial inequalities in adolescents is emblematic. Thus, this study aimed to analyse the race differentials associated with the levels of periodontal disease, regardless of other risk factors. Methods Data from the 2010 national epidemiological survey on oral health were used, with 5445 adolescents (15 to 19 years old). Multinomial logistic regression models were used. Dependent variable was the Community Periodontal Index. Independent variable was self-declared race/colour, categorized as white, pardo (mixed-race identity) and preto (black). The effect of race was controlled in the presence of the covariates sex, years of study, decayed, missing and filled permanent teeth (DMFT index), toothache and self-reported need for dental treatment. Odds Ratio (OR) was estimated and sample weights were considered. Results The simple model showed preto with 2.7 (p &lt; 0.05) and 8 (p &lt; 0.05) times more likely to have shallow and deep periodontal pockets, respectively, compared to white. Pardo was 1.5 (p &lt; 0.05) times more likely to have periodontal calculus. In the multiple model, even in the presence of all independent covariates, preto showed association with shallow pockets (OR = 2.51, p &lt; 0.05) and pardo showed association with the presence of calculus (OR = 1.37, p &lt; 0.05). Conclusions Regardless of sex, education, perception of pain and need for treatment and the DMFT index, race/colour was associated with periodontal problems. It should be noted that skin colour is not a biological risk factor for periodontal disease. However, the findings of this study revealed racial inequities regardless of socioeconomic variables. Key messages Raises the need to guarantee health as a resource for social development, with science having a fundamental role in recovering the citizenship of this historically forgotten population. The findings of this study revealed racial inequities regardless of socioeconomic variables.

Prevalence of Cognitive Impairment and Dementia in Older Adults Living at High Altitude: A Systematic Review and Meta-Analysis

2021 ◽  
pp. 1-11
Author(s):  
Diego Urrunaga-Pastor ◽  
Diego Chambergo-Michilot ◽  
Fernando M. Runzer-Colmenares ◽  
Josmel Pacheco-Mendoza ◽  
Vicente A. Benites-Zapata
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
High Altitude ◽  
Web Of Science ◽  
Meta Analysis ◽  
Cross Sectional ◽  
Language Restriction ◽  
Newcastle Ottawa Scale ◽  
Meta Analyses ◽  
Ottawa Scale

<b><i>Introduction:</i></b> Dementia is a chronic disease with a variable prevalence throughout the world; however, this could be higher at high-altitude populations. We aimed to summarize the prevalence of cognitive impairment and dementia in older adults living at high altitude. <b><i>Methods:</i></b> We searched in PubMed, Medline, Scopus, Web of Science, and Embase and included the studies published from inception to July 20, 2020, with no language restriction, which reported the frequency of cognitive impairment or dementia in older adults living at high-altitude populations. Random-effects meta-analyses were performed to calculate the overall prevalence and 95% confidence intervals (95% CI) of cognitive impairment and dementia. The risk of bias was evaluated using the Newcastle-Ottawa Scale (NOS) adapted for cross-sectional studies. <b><i>Results:</i></b> Six studies were included (3,724 participants), and 5 of the 6 included studies were carried out in Latin America. The altitude ranged from 1,783 to 3,847 m, the proportion of women included varied from 38.7 to 65.6%, and the proportion of participants with elementary or illiterate educational level ranged from 71.7 to 97.6%. The overall prevalence of cognitive impairment was 22.0% (95% CI: 8–40, <i>I</i><sup>2</sup>: 99%), and the overall prevalence of dementia was 11.0% (95% CI: 6–17, <i>I</i><sup>2</sup>: 92%). In a subgroup analysis according to the instrument used to evaluate cognitive impairment, the prevalence of cognitive impairment was 21.0% (95% CI: 5–42, <i>I</i><sup>2</sup>: 99%) in the MMSE group while the prevalence was 29.0% (95% CI: 0–78) in the non-MMSE group. <b><i>Conclusions:</i></b> The prevalence of cognitive impairment and dementia in older adults living at high altitude is almost twice the number reported in some world regions.

scholarly journals Arm Based on LEg blood pressures (ABLE-BP): can systolic leg blood pressure measurements predict systolic brachial blood pressure? Protocol for an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration

BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e040481
Author(s):  
Sinead T J McDonagh ◽  
James P Sheppard ◽  
Fiona C Warren ◽  
Kate Boddy ◽  
Leon Farmer ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Public Involvement ◽  
Meta Analysis ◽  
Patient And Public Involvement ◽  
Prognostic Models ◽  
Individual Participant Data ◽  
Dissemination Strategy ◽  
Cross Sectional ◽  
Individual Participant ◽  
Meta Analyses

IntroductionBlood pressure (BP) is normally measured on the upper arm, and guidelines for the diagnosis and treatment of high BP are based on such measurements. Leg BP measurement can be an alternative when brachial BP measurement is impractical, due to injury or disability. Limited data exist to guide interpretation of leg BP values for hypertension management; study-level systematic review findings suggest that systolic BP (SBP) is 17 mm Hg higher in the leg than the arm. However, uncertainty remains about the applicability of this figure in clinical practice due to substantial heterogeneity.AimsTo examine the relationship between arm and leg SBP, develop and validate a multivariable model predicting arm SBP from leg SBP and investigate the prognostic association between leg SBP and cardiovascular disease and mortality.Methods and analysisIndividual participant data (IPD) meta-analyses using arm and leg SBP measurements for 33 710 individuals from 14 studies within the Inter-arm blood pressure difference IPD (INTERPRESS-IPD) Collaboration. We will explore cross-sectional relationships between arm and leg SBP using hierarchical linear regression with participants nested by study, in multivariable models. Prognostic models will be derived for all-cause and cardiovascular mortality and cardiovascular events.Ethics and disseminationData originate from studies with prior ethical approval and consent, and data sharing agreements are in place—no further approvals are required to undertake the secondary analyses proposed in this protocol. Findings will be published in peer-reviewed journal articles and presented at conferences. A comprehensive dissemination strategy is in place, integrated with patient and public involvement.PROSPERO registration numberCRD42015031227.

scholarly journals Oral health seeking behaviors of adults in Nebbi District, Uganda: a community-based survey

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Juliet Ocwia ◽  
Ronald Olum ◽  
Pamela Atim ◽  
Florence Laker ◽  
Jerom Okot ◽  
...  
Keyword(s):  
Oral Health ◽  
Dental Health ◽  
Oral Disease ◽  
Tooth Decay ◽  
Oral Diseases ◽  
Health Seeking ◽  
Dental Clinic ◽  
Community Based ◽  
Cost Of Treatment ◽  
Cross Sectional

Abstract Background Dental health is often neglected by the majority of the population and has contributed to the global burden of oral diseases. We assessed awareness, utilization and barriers to seeking oral health care among adults in Nebbi District, Uganda. Methods A community-based, cross sectional study was conducted in the central division, Nebbi District in Uganda among adults between the age of 18 years or older. An interviewer-administered, semi-structured questionnaire was used for data collection on socio-demographic characteristics, oral health awareness, oral health utilization, associated factors and barriers. Results A total of 400 adults with a median age of 32 years (interquartile range 24–43) years were enrolled. More than half (57.5%, n = 230) of the participants were female. Participants identified smoking (42.8%, n = 171) and consumption of sugary foodstuffs (29.0%, n = 116) as risk factors for oral disease. Not brushing was also identified by 260 participants (65.0%) as the cause of tooth decay and 95.8% (n = 383) believed brushing one’s teeth could prevent tooth decay. Of the 51.5% (n = 206) who had experienced a toothache or discomfort 12 months prior to the study but only about half (52%, n = 106) had sought healthcare from a dental clinic or facility. About 89.5% (n = 94) of the participants were able to see a dentist during their last visits. Dental carries (76.6%, n = 70) and gum bleeding (14.9%, n = 14) were the most frequent reasons for visiting a dental clinic, and 73.7% (n = 70) had their tooth extracted. Barriers to seeking oral healthcare were cost of treatment (47.5%, n = 190), and long waiting time (18.5%, n = 74). The odds of seeking oral healthcare was 2.8-fold higher in participants who were being married (Odds ratio (OR): 2.8, 95% CI 1.3–6.3, p = 0.011) and 3.5-fold higher among housewives (COR: 3.5, 95% CI 1.1–11.4, p = 0.040). Conclusion About half of the participants had sought healthcare following a dental condition. Cost of treatment seems to be an important factor affecting utilization of oral health services. Optimization of costs, and creating awareness regarding benefits of utilizing preventive dental services are recommended.

scholarly journals Caregivers’ attitudes, knowledge and practices of oral care at nursing homes in Serbia

2016 ◽  
Vol 73 (7) ◽  
pp. 668-673 ◽  
Author(s):  
Ivica Stancic ◽  
Milos Petrovic ◽  
Aleksandra Popovac ◽  
Miroslav Vasovic ◽  
Nebojsa Despotovic
Keyword(s):  
Oral Health ◽  
Nursing Homes ◽  
Periodontal Disease ◽  
Oral Hygiene ◽  
Oral Care ◽  
The Elderly ◽  
Oral Diseases ◽  
Closed Type ◽  
Work Shifts ◽  
Self Administered Questionnaire

Background/Aim. Within the elderly population, residents in nursing homes, there is a greather risk of caries, periodontal disease and teeth loss. Assistance of caregivers in maintaininig good oral hygiene besides improving oral health can improve of residents general health and the qulity of their lives. The aim of this study was to examine the attitudes of caregivers and knowledge about oral health, as well as the practice regarding oral care they apply at nursing homes in Serbia. Methods. The survey was conducted at the Gerontology Center Belgrade, consisting of four nursing homes located in the urban area. The study included 58 caregivers. They were contacted on working days, in all work shifts, during January, February and March of 2013. They were asked to fill in a self-administered questionnaire consisting of 26 closed-type questions. Results. The caregivers mostly considered that it was very important to take care of oral health of the residents, but 69% responded that the level of their oral health was low or very low. As the main barriers to oral hygiene maintenance, the caregivers indicated lack of time. The caregivers had more knowledge about periodontal disease than about the main cause of caries and its prevention. Formal medical education had the influence on the knowledge about oral diseases. Oral hygiene procedures carried out by the mayority of caregivers were denture cleaning and tooth brushing. Conclusion. The caregivers were aware of the limitations in everyday oral care of nursing homes residents in Serbia, although solving these problems requires the involvement of the entire public health service.

scholarly journals Oral hygiene status of depressed patients

2020 ◽  
Vol 32 (1) ◽  
pp. 63
Author(s):  
Putri Permatasari ◽  
Gilang Yubiliana ◽  
Aulia Iskandarsyah
Keyword(s):  
Oral Health ◽  
Oral Hygiene ◽  
Sampling Method ◽  
Periodontal Diseases ◽  
Critical Factor ◽  
Depression Symptoms ◽  
Oral Diseases ◽  
Cross Sectional ◽  
Depressed Patients ◽  
Score Point

Introduction: Oral hygiene is one of the most critical factor in maintaining oral health. Depression symptoms may affect an individual’s oral health due to poor health behaviour, making depressed individuals prone to oral diseases such as caries and periodontal diseases. This study was aimed to obtain the oral hygiene status overview of depressed patients in West Java Psychiatric Hospital. Methods: This study was an observational descriptive with a cross-sectional approach to depressed patients (F.32 ICD Code). The measuring instrument used was Oral Hygiene Index-Simplified (OHI-S). Based on OHI-S, oral hygiene can be assessed into poor within 3.0 – 6.0 score point, fair within 1.3-3.0 score point, or good within 0.0 – 1.2 score point. Results: There were 30 respondents recruited using a purposive sampling method. Based on the plaque index, 1 respondent (3%) fell into good category, 23 respondents (77%) fell into the fair category, and 6 respondents (20%) fell into poor category. Based on the calculus index, 7 respondents (23%) fell into good category, 10 respondents (60%) fell into the fair category, and 5 respondents (17%) fell into poor category. Based on OHI-S, 2 respondents (7%) fell into the good category, 18 respondents (60%) fell into the fair category, and 10 respondents (33%) fell into poor category. Conclusion: Oral hygiene in-dex of depressed patients was categorised as fair.

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