scholarly journals The Functional and Morphological Changes of the Cervical Intervertebral Disc after Applying Lordotic Curve Controlled Traction: A Double-Blind Randomized Controlled Study

2019 ◽  
Vol 16 (12) ◽  
pp. 2162 ◽  
Author(s):  
Chang-Hyung Lee ◽  
Sung Jin Heo ◽  
So Hyun Park ◽  
Hee Seok Jeong ◽  
Soo-Yeon Kim
Keyword(s):  
Intervertebral Disc ◽  
Treatment Outcomes ◽  
Morphological Changes ◽  
Controlled Trial ◽  
Controlled Study ◽  
Functional Score ◽  
Intervertebral Disc Disease ◽  
Disc Disease ◽  
Randomized Controlled ◽  
Functional Scores

The newly developed cervical lordotic curve-controlled traction (C-LCCT) appears to be an ideal method to improve the treatment outcome in patients with cervical intervertebral disc disease. The purpose of this study was to investigate the treatment outcomes of C-LCCT including the functional and morphological changes of the cervical intervertebral disc compared to traditional traction (TT) with a randomized controlled trial design. A total of 40 patients with cervical intervertebral disc disease at the C5/6 level confirmed by magnetic resonance imaging were recruited and assigned to either the C-LCCT group or the TT group. The comprehensive health status changes of the patients were recorded using pain and functional scores (Visual Analogue Scale, Oswestry Disability Index) and morphological changes (cervical lordosis, cervical central canal area) before and after the traction treatment. Both groups showed a significant improvement in pain scores after traction (p < 0.05). The functional score and morphological changes improved significantly after treatment in the C-LCCT group. However, there was no significant improvement in the TT group (p < 0.05). The C-LCCT showed significant pain, functional, and morphological improvement compared to TT. C-LCCT could be effective in improving the treatment outcomes of the traction technique in patients with cervical intervertebral disc disease.

scholarly journals Functional Changes in Patients and Morphological Changes in the Lumbar Intervertebral Disc after Applying Lordotic Curve-Controlled Traction: A Double-Blind Randomized Controlled Study

Medicina ◽  
2019 ◽  
Vol 56 (1) ◽  
pp. 4 ◽  
Author(s):  
Chang-Hyung Lee ◽  
Sung Jin Heo ◽  
So Hyun Park ◽  
Hee Seok Jeong ◽  
Soo-Yeon Kim
Keyword(s):  
Intervertebral Disc ◽  
Morphological Changes ◽  
Controlled Study ◽  
Intervertebral Disc Disease ◽  
Disc Disease ◽  
Double Blind ◽  
Lumbar Intervertebral Disc ◽  
Linear Type ◽  
Functional Changes ◽  
Functional Scores

Background and Objectives: Lumbar traction is widely used as a non-operative treatment for lumbar intervertebral disc disease. The effect of traditional traction (TT) using linear-type traction devices remains controversial for various reasons, including technical limitations. Thus, the purpose of this study was to compare the effects of the newly developed lumbar lordotic curve-controlled traction (L-LCCT) and TT on functional changes in patients and morphological changes in the vertebral disc. Materials and Methods: A total of 40 patients with lumbar intervertebral disc disease at the L4/5 or L5/S1 level as confirmed by magnetic resonance imaging were recruited and divided into two groups (L-LCCT or TT). The comprehensive health status changes of the patients were recorded using pain and functional scores (the visual analogue scale, the Oswestry Disability Index, and the Roland–Morris Disability Questionnaire) and morphological changes (in the lumbar central canal area) before and after traction treatment. Results: Pain scores were significantly decreased after traction in both groups (p < 0.05). However, functional scores and morphological changes improved significantly after treatment in the L-LCCT group only (p < 0.05). Conclusions: We suggest that L-LCCT is a viable option for resolving the technical limitations of TT by maintaining the lumbar lordotic curve in patients with lumbar intervertebral disc disease.

Randomized controlled trial of pregabalin for analgesia after surgical treatment of intervertebral disc disease in dogs

2020 ◽  
Vol 49 (5) ◽  
pp. 905-913
Author(s):  
Philipp A. Schmierer ◽  
Julia Tünsmeyer ◽  
Andrea Tipold ◽  
Sonja Hartnack‐Wilhelm ◽  
Piotr Lesczuk ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Surgical Treatment ◽  
Intervertebral Disc ◽  
Controlled Trial ◽  
Intervertebral Disc Disease ◽  
Disc Disease ◽  
Randomized Controlled

Application of evidence-based medicine to recurrence of Hansen’s type I intervertebral disc disease in dogs: A justification for continuation of study into percutaneous laser disc ablation?

2012 ◽  
Vol 1 (2) ◽  
Author(s):  
Jude T. Bordelon ◽  
Kenneth E. Bartels
Keyword(s):  
Intervertebral Disc ◽  
Clinical Signs ◽  
Controlled Study ◽  
Type I ◽  
Search Term ◽  
Clinical Question ◽  
Intervertebral Disc Disease ◽  
Disc Disease ◽  
Level Of Evidence ◽  
Long Term Outcome

AbstractTo review and evaluate the literature reporting results of prophylactic surgical procedures for Hansen’s type I intervertebral disc disease.Systematic literature review.Online bibliographic searches of abstracts through PubMed and the Veterinary Information Network (VIN) were performed using the searchable term “canine intervertebral disc disease and recurrence”. The resources were evaluated in regard to the ability of the retrieved references to directly address the clinical question as follows: which prophylactic technique when considered with or without surgery will consistently reduce or eliminate the recurrence of clinical signs associated with Hansen’s type I intervertebral disc disease. All studies were compared and evaluated with regard to study design, technique utilized, short and long-term outcome, and evidence classification.An online bibliographical search was performed in PubMed using the full search term of “canine intervertebral disc disease and recurrence” resulted in 20 total sources, and of those sources 13 contained information pertaining to the clinical question. The same search term when used in the VIN search engine under the classification of journal abstracts resulted in 43 total results with 18 applicable resources. In review of both searches, 13 resources were listed in both searches. Of the 18 obtained by the VIN search 14 were available in the English language. No resources were included in class I level of evidence, and only one was considered as class II level of evidence. As for the remaining studies, three results were classified as class III studies, and the remaining reports were classified as class IV level of evidence.Although direct extrapolation of the evidence provided by the search to the clinical scenario is not possible, this review will hopefully provide the basis for development of a randomized controlled study to provide for a clear need in evidence for prevention of intervertebral disc extrusion in dogs.

scholarly journals Autologous Matrix-Induced Chondrogenesis (AMIC) and AMIC Enhanced by Autologous Concentrated Bone Marrow Aspirate (BMAC) Allow for Stable Clinical and Functional Improvements at up to 9 Years Follow-Up: Results from a Randomized Controlled Study

2019 ◽  
Vol 8 (3) ◽  
pp. 392 ◽  
Author(s):  
Laura de Girolamo ◽  
Herbert Schönhuber ◽  
Marco Viganò ◽  
Corrado Bait ◽  
Alessandro Quaglia ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Aspirate ◽  
Controlled Trial ◽  
Activity Level ◽  
Controlled Study ◽  
Level Of Evidence ◽  
Chondral Lesions ◽  
Randomized Controlled ◽  
Functional Scores

The aims of the study were to evaluate long-term outcomes after autologous matrix-induced chondrogenesis (AMIC) in the treatment of focal chondral lesions and to assess the possible improvements given by the combination of this technique with bone marrow aspirate concentrate (BMAC). Twenty-four patients (age range 18–55 years) affected by focal knee chondral lesions were treated with standard AMIC or AMIC enhanced by BMAC (AMIC+). Pain (Visual Analogue Scale (VAS)) and functional scores (Lysholm, International Knee Documentation Committee (IKDC), Tegner, Knee injury and Osteoarthritis Outcome Score (KOOS)) were collected pre-operatively and then at 6, 12, 24, 60, and 100 months after treatment. Magnetic resonance imaging (MRI) evaluation was performed pre-operatively and at 6, 12, and 24 months follow-ups. Patients treated with AMIC+ showed higher Lysholm scores (p = 0.015) and lower VAS (p = 0.011) in comparison with patients in the standard AMIC group at the 12 months follow-up. Both treatments allowed for functional and pain improvements with respect to pre-operative levels lasting up to 100 months. MRI revealed consistent cartilage repair at 24 months in both groups. This study shows that AMIC and AMIC+ are effective treatments for focal chondral lesions with beneficial effect lasting up to 9 years. AMIC+ allows for faster recovery from injury, and is thus more indicated for patients requiring a prompt return to activity. Level of evidence: II, randomized controlled trial in an explorative cohort.

scholarly journals MRI signal changes and their association with intervertebral disc disease in canine vertebral endplates

2019 ◽  
Vol 72 (1) ◽  
Author(s):  
Emma Deards ◽  
Dylan N. Clements ◽  
Tobias Schwarz
Keyword(s):  
Intervertebral Disc ◽  
Morphological Changes ◽  
Vertebral Endplate ◽  
Intervertebral Disc Disease ◽  
Disc Disease ◽  
Cross Sectional ◽  
Endplate Changes ◽  
Adjacent Disc ◽  
Mri Scans ◽  
Vertebral Endplates

Abstract Background This study was undertaken to determine the relationship between intervertebral endplate changes and intervertebral disc disease. This study was designed as a cross-sectional, observational study. Two hundred thirteen canine MRI scans performed between 2007 and 2014 were retrieved from a digital image archive. Scans which included any sagittal sections of the vertebral column from C1 to S1 were assessed for morphological changes to the vertebral endplate. Results There was found to be a significant association between vertebral endplate changes and intervertebral disc disease of the adjacent disc (P = 0.021). There was not found to be any significant association between dogs having vertebral endplate changes and having intervertebral disc disease (P = 0.38). There was found to be a highly significant association between discs with vertebral endplate changes on both associated vertebrae (bilateral) and having intervertebral disc disease (P = < 0.0001). Conclusions The presence of endplate changes should alert the observer to closely examine the disc, as intervertebral disc disease is mildly more likely to occur adjacent to these changes.

scholarly journals A Comparative Assessment of Orthodontic Treatment Outcomes of Mild Skeletal Class III Malocclusion Between Facemask and Facemask in Combination with a Miniscrew For Anchorage in Growing Patients: A Single-center, Prospective Randomized Controlled trial

2019 ◽  
Vol 90 (1) ◽  
pp. 3-12 ◽  
Author(s):  
Masahiro Seiryu ◽  
Hiroto Ida ◽  
Atsushi Mayama ◽  
Satoshi Sasaki ◽  
Shutaro Sasaki ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Controlled Trial ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Skeletal Class ◽  
Randomized Controlled ◽  
Group 12 ◽  
Prospective Randomized Controlled Trial ◽  
Group A ◽  
Negative Side Effects

ABSTRACT Objectives To investigate the hypothesis that there is difference in the treatment outcomes of milder skeletal Class III malocclusion between facemask and facemask in combination with a miniscrew in growing patients. Materials and Methods Patients were randomly divided into two groups. In one group, the patients were treated with facemask therapy (FM group: 12 males, eight females, average age: 10 years, 5 months ± 1 year, 8 months). In the other group, patients were treated with facemask therapy along with a miniscrew (FM+MS group: 12 males, seven females, average age: 11 years, 1 month ± 1 year, 3 months). A lingual arch with hooks was fixed to the maxillary arch in both groups and a protractive force of 500 g was applied from the facemask to the hooks. The patients were instructed to use the facemask for 12 hours per day. In the FM+MS group, a miniscrew was inserted into the palate and fixed to the lingual arch. Results Mobility and loosening of the miniscrew were not observed during treatment. Lateral cephalometric analysis showed that SNA, SN-ANS, and ANB values were significantly increased in the FM+MS group compared with those for the FM group (SNA, 1.1° SN-ANS, 1.3° ANB, 0.8°). Increase in proclination of maxillary incisors was significantly greater in the FM group than in the FM+MS group (U1-SN, 5.0°). Conclusions During treatment of milder skeletal Class III malocclusion, facemask therapy along with a miniscrew exhibits fewer negative side effects and delivers orthopedic forces more efficiently to the maxillary complex than facemask therapy alone.

scholarly journals Effectiveness of Community-Delivered Functional Power Training Program for Frail and Pre-frail Community-Dwelling Older Adults: a Randomized Controlled Study

2021 ◽  
Author(s):  
Nien Xiang Tou ◽  
Shiou-Liang Wee ◽  
Wei Ting Seah ◽  
Daniella Hui Min Ng ◽  
Benedict Wei Jun Pang ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Controlled Trial ◽  
Community Dwelling ◽  
Controlled Study ◽  
Power Training ◽  
Frail Older Adults ◽  
Frailty Status ◽  
Randomized Controlled ◽  
Community Dwelling Older Adults

AbstractTranslation of community-based functional training for older adults to reduce frailty is still lacking. We evaluated the effectiveness and implementation of a community-delivered group-based functional power training (FPT) program for frail older adults within their neighborhoods. A two-arm, multicenter assessor-blind stratified randomized controlled trial was conducted at four local senior activity centers in Singapore. Sixty-one community-dwelling older adults with low handgrip strength were randomized to intervention (IG) or control (CG) group. The IG underwent the FPT program (power and balance exercises using simple equipment) delivered by a community service provider. The 12-week program comprised 2 × 60 min sessions/week. CG continued usual activities at the centers. Functional performance, muscle strength, and frailty status were assessed at baseline and 3 months. Program implementation was evaluated using RE-AIM framework. The program was halted due to Coronavirus Disease 2019-related suspension of senior center activities. Results are reported from four centers, which completed the program. IG showed significantly greater improvement in the Short Physical Performance Battery test as compared to CG (p = 0.047). No effects were found for timed up and go test performance, muscle strength, and frailty status. The community program exhibited good reach, effectiveness, adoption, and implementation. Our study demonstrated that FPT was associated with greater improvement in physical function in pre-frail/frail participants as compared to exercise activities offered at local senior activity centers. It is a feasible intervention that can be successfully implemented for frail older adults in their neighborhoods. Trial registration ClinicalTrials.gov, NCT04438876. Registered 19 June 2020–retrospectively registered.

scholarly journals Efficacy of axial TheraTogs on gait pattern in children with dyskinetic cerebral palsy: a randomized controlled trial

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Shamekh Mohamed El-Shamy ◽  
Ehab Mohamed Abd El Kafy
Keyword(s):  
Cerebral Palsy ◽  
Physical Therapy ◽  
Muscle Tone ◽  
Controlled Trial ◽  
Gait Pattern ◽  
Controlled Study ◽  
Control Group ◽  
Randomized Controlled ◽  
Gait Parameters ◽  
Experimental Group

Abstract Background TheraTogs promotes proprioceptive sense of a child with cerebral palsy and improves abnormal muscle tone, posture alignment, balance, and gait. Therefore, the aim of this study was to investigate the efficacy of TheraTogs orthotic undergarment on gait pattern in children with dyskinetic cerebral palsy. Thirty children with dyskinetic cerebral palsy were selected for this randomized controlled study. They were randomly assigned to (1) an experimental group that received TheraTogs orthotic undergarment (12 h/day, 3 days/week) plus traditional physical therapy for 3 successive months and (2) a control group that received only traditional physical therapy program for the same time period. Gait parameters were measured at baseline and after 3 months of intervention using Pro-Reflex motion analysis. Results Children in both groups showed significant improvements in the gait parameters (P < 0.05), with significantly greater improvements in the experimental group than in the control group. Conclusions The use of TheraTogs may have a positive effect to improve gait pattern in children with dyskinetic cerebral palsy. Trial registration This trial was registered in the ClinicalTrial.gov PRS (NCT03037697).

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