scholarly journals Bisphenol A and Ovarian Reserve among Infertile Women with Polycystic Ovarian Syndrome

2016 ◽  
Vol 14 (1) ◽  
pp. 18 ◽  
Author(s):  
Wei Zhou ◽  
Fang Fang ◽  
Wenting Zhu ◽  
Zi-Jiang Chen ◽  
Yanzhi Du ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Ovarian Reserve ◽  
Polycystic Ovarian Syndrome ◽  
Infertile Women ◽  
Ovarian Syndrome

scholarly journals Effect of laparoscopic ovarian drilling on serum anti-Mullerian hormone in clomiphene citrate resistant polycystic ovarian syndrome patients

2021 ◽  
Author(s):  
Ambika Shankar ◽  
Oby Nagar ◽  
Shakuntla . ◽  
Suman Meghwal
Keyword(s):  
Ovarian Reserve ◽  
Polycystic Ovarian Syndrome ◽  
Clomiphene Citrate ◽  
Interventional Study ◽  
Ovarian Insufficiency ◽  
Common Cause ◽  
Laparoscopic Ovarian Drilling ◽  
Ovarian Drilling ◽  
Ovarian Syndrome ◽  
Anovulatory Infertility

Background: PCOS (polycystic ovarian syndrome) is the most common cause of anovulatory infertility, the purpose of our study was to see the effect of laparoscopic ovarian drilling on the ovarian reserve (with AMH as an indicator of ovarian reserve) and its safety as 2nd line of treatment in patients resistant to clomiphene citrate.Methods: This was a prospective interventional study conducted on 40 clomiphene citrate resistant PCOS women attending the infertility OPD. This study was conducted over a period of 1 year May 2019 to May 2020. Laparoscopic ovarian drilling (LOD) was done and these subjects were studied preoperatively and postoperatively on day 7 and day 30 for change in AMH (anti-Mullerian hormone) levels.Results: There is a significant change in the AMH level post LOD day 7 and 30 but not so severe that it will lead to premature ovarian failure. The amount of drop in AMH (day 30) increases till 20 ng/ml beyond which it shows a decrease.Conclusions: If LOD is done in a proper manner in women with sufficient ovarian reserve (high AMH), it will not adversely affect the ovarian reserve (the fall is not enough to cause premature ovarian insufficiency). 

scholarly journals Mental and personality disorders in infertile women with polycystic ovary: a case-control study

2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Infertile Women ◽  
The Mean ◽  
Ovarian Syndrome ◽  
Control Study

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.

scholarly journals Clomiphene-Metformin in Comparison with Letrozole-Metformin in Overweight Infertile Women with PCOS

2020 ◽  
Vol 4 (2) ◽  
pp. 01-08
Author(s):  
Mohamed EL-Gharib
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Clomiphene Citrate ◽  
First Line ◽  
Overweight Women ◽  
Infertile Women ◽  
First Line Therapy ◽  
Line Therapy ◽  
Long Time ◽  
The Difference ◽  
Ovarian Syndrome

Background: polycystic ovarian syndrome (PCOS) is a common cause of infertility and is associated with chronic anovulation and hyperandrogenemia. Clomiphene citrate (CC) is still the first-line therapy for ovulation induction in these patients. Metformin, a biguanide, has been used to treat insulin resistance in women with PCOS. Furthermore, many reports confirmed that the addition of metformin to CC in the CC-resistant PCOS was highly effective in achieving ovulation. Letrozole, an aromatase inhibitor, has attracted attention for a long time to induce ovulation. Aim of the work: In the current study, we aimed to compare the effect of administration of combined metformin–Clomiphene Citrate to that of combined metformin–letrozole in the induction of ovulation in infertile overweight women with PCOS. 40 infertile overweight cases with PCO were included. Methods: Sixty participants had received metformin in aggregate with both CC (100 mg) or and similar number received letrozole (5 mg) plus metformin for 5 days starting from 3rd day of their menstrual cycle. Results: The cumulative pregnancy rate CC-metformin was 21.66% and letrozole-metformin was 25%, the difference is insignificant. Conclusion: CC and letrozole are similarly viable in the treatment of overweight women with PCOS, when joined with metformin treatment.

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