scholarly journals Comparison of Individual and Combined Effects of Four Endocrine Disruptors on Estrogen Receptor Beta Transcription in Cerebellar Cell Culture: The Modulatory Role of Estradiol and Triiodo-Thyronine

2016 ◽  
Vol 13 (6) ◽  
pp. 619 ◽  
Author(s):  
Gergely Jocsak ◽  
David Kiss ◽  
Istvan Toth ◽  
Greta Goszleth ◽  
Tibor Bartha ◽  
...  
Keyword(s):  
Cell Culture ◽  
Estrogen Receptor ◽  
Endocrine Disruptors ◽  
Estrogen Receptor Beta ◽  
Combined Effects ◽  
Cerebellar Cell ◽  
Receptor Beta

scholarly journals Correction: Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
Author(s):  
Carine Bossard ◽  
Muriel Busson ◽  
David Vindrieux ◽  
Françoise Gaudin ◽  
Véronique Machelon ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Tumor Suppressor ◽  
Epithelial Ovarian Cancer ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Receptor Beta ◽  
Correction Potential

scholarly journals Potential Role of Estrogen Receptor Beta as a Tumor Suppressor of Epithelial Ovarian Cancer

PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e44787 ◽  
Author(s):  
Carine Bossard ◽  
Muriel Busson ◽  
David Vindrieux ◽  
Françoise Gaudin ◽  
Véronique Machelon ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Estrogen Receptor ◽  
Tumor Suppressor ◽  
Epithelial Ovarian Cancer ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Receptor Beta

W1961 Gender-Related Differential Susceptibility to Celecoxib On Adenoma Formation: Potential Role of Estrogen-Receptor Beta

2009 ◽  
Vol 136 (5) ◽  
pp. A-762
Author(s):  
Jennifer Koetsier ◽  
Ramesh K. Wali ◽  
John Hart ◽  
Dhananjay Kunte ◽  
Laura K. Bianchi ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Potential Role ◽  
Estrogen Receptor Beta ◽  
Differential Susceptibility ◽  
Formation Potential ◽  
Receptor Beta

scholarly journals Role of estrogen receptor beta in colonic epithelium

2006 ◽  
Vol 103 (8) ◽  
pp. 2959-2964 ◽  
Author(s):  
O. Wada-Hiraike ◽  
O. Imamov ◽  
H. Hiraike ◽  
K. Hultenby ◽  
T. Schwend ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Beta ◽  
Colonic Epithelium ◽  
Receptor Beta

scholarly journals Role of estrogen receptor beta in uterine stroma and epithelium: Insights from estrogen receptor beta-/- mice

2006 ◽  
Vol 103 (48) ◽  
pp. 18350-18355 ◽  
Author(s):  
O. Wada-Hiraike ◽  
H. Hiraike ◽  
H. Okinaga ◽  
O. Imamov ◽  
R. P. A. Barros ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Beta ◽  
Receptor Beta

scholarly journals The role of estrogen receptor-beta gene +1730G/A polymorphisms in recurrent pregnancy loss

Medicine ◽  
2021 ◽  
Vol 100 (7) ◽  
pp. e24398
Author(s):  
Fangxiang Mu ◽  
Minge Shi ◽  
Li Huang ◽  
Dafen Wang ◽  
Aiqun Shen
Keyword(s):  
Estrogen Receptor ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Estrogen Receptor Beta ◽  
Beta Gene ◽  
Receptor Beta

scholarly journals Estrogen represses Tgfbr1 and Bmpr1a expression via estrogen receptor beta in MC3T3-E1 cells

2017 ◽  
Author(s):  
Hanliang He ◽  
Chunqing Wang ◽  
Qifeng Tang ◽  
Fan Yang ◽  
Youjia Xu
Keyword(s):  
Estrogen Receptor ◽  
Deep Sequencing ◽  
Target Genes ◽  
Estrogen Receptor Beta ◽  
Osteoblastic Cell ◽  
Newborn Mouse ◽  
Osteoblastic Cell Line ◽  
Er Alpha ◽  
Receptor Beta

AbstractMC3T3-E1 is a clonal pre-osteoblastic cell line derived from newborn mouse calvaria, which is commonly used in osteoblast studies. To investigate the effects of estrogen on osteoblasts, we treated MC3T3-E1 cells with various concentrations of estrogen and assessed their proliferation. Next, we performed RNA deep sequencing to investigate the effects on estrogen target genes. Bmpr1a and Tgfbr1, important participants in the TGF-beta signaling pathway, were down-regulated in our deep sequencing results. Bioinformatics analysis revealed that estrogen receptor response elements (EREs) were present in the Bmpr1a and Tgfbr1 promoters. Culturing the cells with the estrogen receptor (ER) alpha or beta antagonists 1,3-bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride (MPP) or 4-[2-phenyl-5,7-bis(trifluoromethyl) pyrazolo[1,5-alpha]pyrimidin-3-yl] phenol (PTHPP), respectively, demonstrated that ER beta is involved in the estrogen-mediated repression of Tgfbr1 and Bmpr1a.The chromatin immunoprecipitation (ChIP) results were consistent with the conclusion that E2 increased the binding of ER beta at the EREs located in the Tgfbr1 and Bmpr1a promoters. Our research provides new insight into the role of estrogen in bone metabolisms.

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