scholarly journals Staggered Chromosomal Hybrid Zones in the House Mouse: Relevance to Reticulate Evolution and Speciation

Genes ◽  
2010 ◽  
Vol 1 (2) ◽  
pp. 193-209 ◽  
Author(s):  
İslam Gündüz ◽  
Christianne L. Pollock ◽  
Mabel D. Giménez ◽  
Daniel W. Förster ◽  
Thomas A. White ◽  
...  
Keyword(s):  
House Mouse ◽  
Reticulate Evolution ◽  
Hybrid Zones

scholarly journals Copy number variation of the putative speciation genes in the European house mouse hybrid zone

2021 ◽  
Author(s):  
Alexey Yanchukov ◽  
Zusana Hiadlovska ◽  
Zeljka Pezer ◽  
Milos Macholan ◽  
Jaroslav Pialek ◽  
...  
Keyword(s):  
Copy Number Variation ◽  
House Mouse ◽  
Hybrid Zone ◽  
Copy Number ◽  
Digital Pcr ◽  
Gene Copy ◽  
Ancestral Population ◽  
Hybrid Zones ◽  
Interaction Sites ◽  
Number Variation

Hybrid zones have long been described as "windows on the evolutionary process", and studying them has become even more important since the advance in the genome analysis tools. The hybrid zone between two subspecies of the house mouse (Mus musculus musculus and Mus m. domesticus) is a unique model speciation system to study fine scale interactions of recently diverged genomes. Here, we explore the role of gene Copy Number Variation in shaping the barrier to introgression in the hybrid zone within a previously established transect in Central Europe. The CNV of seven pre-selected candidate genes was determined via droplet-digital PCR and analyzed in the context of ~500k SNPs, with the ancestral population (i.e. musculus or domesticus) of every SNP allele previously inferred in the admixed individuals (Baird et al., in prep.). The copy numbers of five genes were clearly associated with the prevalence of either musculus or domesticus genomes across the hybrid zone. In three cases, the highest and/or outlying levels of association were observed at or very close to the annotated positions of the respective gene amplicons, demonstrating the power of our approach in confirming the reference locations of copy number variants. Notably, several other reference locations were recognized as positive outliers in the association with particular CNV genes, possibly representing the extra gene copies and/or their epistatic interaction sites.

scholarly journals Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Leslie M Turner ◽  
Bettina Harr
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Hybrid Sterility ◽  
Testis Weight ◽  
Hybrid Zones ◽  
Incipient Species ◽  
Complex Interactions ◽  
Genetic Mechanisms ◽  
Resolution Mapping ◽  
Genomic Regions

Mapping hybrid defects in contact zones between incipient species can identify genomic regions contributing to reproductive isolation and reveal genetic mechanisms of speciation. The house mouse features a rare combination of sophisticated genetic tools and natural hybrid zones between subspecies. Male hybrids often show reduced fertility, a common reproductive barrier between incipient species. Laboratory crosses have identified sterility loci, but each encompasses hundreds of genes. We map genetic determinants of testis weight and testis gene expression using offspring of mice captured in a hybrid zone between M. musculus musculus and M. m. domesticus. Many generations of admixture enables high-resolution mapping of loci contributing to these sterility-related phenotypes. We identify complex interactions among sterility loci, suggesting multiple, non-independent genetic incompatibilities contribute to barriers to gene flow in the hybrid zone.

scholarly journals Genome-Wide Mapping In A House Mouse Hybrid Zone Reveals Hybrid Sterility Loci And Dobzhansky-Muller Interactions

2014 ◽  
Author(s):  
Leslie Turner ◽  
Bettina Harr
Keyword(s):  
House Mouse ◽  
Hybrid Zone ◽  
Hybrid Sterility ◽  
Testis Weight ◽  
Hybrid Zones ◽  
Incipient Species ◽  
Complex Interactions ◽  
Genetic Mechanisms ◽  
Resolution Mapping ◽  
Genomic Regions

Mapping hybrid defects in contact zones between incipient species can identify genomic regions contributing to reproductive isolation and reveal genetic mechanisms of speciation. The house mouse features a rare combination of sophisticated genetic tools and natural hybrid zones between subspecies. Male hybrids often show reduced fertility, a common reproductive barrier between incipient species. Laboratory crosses have identified sterility loci, but each encompasses hundreds of genes. We map genetic determinants of testis weight and testis gene expression using offspring of mice captured in a hybrid zone between M. musculus musculus and M. m. domesticus. Many generations of admixture enables high-resolution mapping of loci contributing to these sterility-related phenotypes. We identify complex interactions among sterility loci, suggesting multiple, non-independent genetic incompatibilities contribute to barriers to gene flow in the hybrid zone.

Chromosomal hybrid zones in the house mouse

2012 ◽  
pp. 407-430 ◽  
Author(s):  
Heidi C. Hauffe ◽  
Mabel D. Giménez ◽  
Jeremy B. Searle ◽  
Jaroslav Pialek
Keyword(s):  
House Mouse ◽  
Hybrid Zones

scholarly journals Cryptic and extensive hybridization between ancient lineages of American crows

2018 ◽  
Author(s):  
David L. Slager ◽  
Kevin L. Epperly ◽  
Renee R. Ha ◽  
Sievert Rohwer ◽  
Chris Wood ◽  
...  
Keyword(s):  
British Columbia ◽  
Nuclear Dna ◽  
Continuous Distribution ◽  
Morphological Differentiation ◽  
Reticulate Evolution ◽  
F1 Hybrids ◽  
Hybrid Zones ◽  
Phenotypic Characters ◽  
Genomic Study ◽  
American Crows

AbstractMost species and therefore most hybrid zones have historically been described using phenotypic characters. However, both speciation and hybridization can occur with negligible morphological differentiation. The Northwestern Crow (Corvus caurinus) and American Crow (Corvus brachyrhynchos) are sister taxonomic species with a continuous distribution that lack reliable traditional characters for identification. In this first population genomic study of Northwestern and American crows, we use genomic SNPs (nuDNA) and mtDNA to investigate whether these crows are genetically differentiated and the extent to which they may hybridize. We found that American and Northwestern crows have distinct evolutionary histories, supported by two nuDNA ancestry clusters and two 1.1%-divergent mtDNA clades dating to the late Pleistocene, when glacial advances may have isolated crow populations in separate refugia. We document extensive hybridization, with geographic overlap of mtDNA clades and admixture of nuDNA across >1,400 km of western Washington and western British Columbia. This broad hybrid zone consists of late-generation hybrids and backcrosses, not recent (e.g., F1) hybrids. Nuclear DNA and mtDNA clines were both centered in southwestern British Columbia, farther north than previously postulated. The mtDNA cline was narrower than the nuDNA cline, consistent with Haldane’s rule but not sex-biased dispersal. Overall, our results suggest a history of reticulate evolution in American and Northwestern crows, consistent with potentially recurring neutral expansion(s) from Pleistocene glacial refugia followed by lineage fusion(s). However, we do not rule out a contributing role for more recent potential drivers of hybridization, such as expansion into human-modified habitats.

Systematics and evolution of Nepenthes

2018 ◽  
Author(s):  
Charles Clarke ◽  
Jan Schlauer ◽  
Jonathan Moran ◽  
Alastair Robinson
Keyword(s):  
Southeast Asia ◽  
Analytical Methods ◽  
Best Practice ◽  
Species Concept ◽  
Reticulate Evolution ◽  
Ecological Information ◽  
Plastid Genomes ◽  
The Status ◽  
Species Descriptions ◽  
Adequate Research

Nepenthes is a genus of 130-160 species, almost half of which were described after 2001. The recent, rapid increase in species descriptions has been driven by application of a less rigorous species concept by botanists, taxonomic inflation, and discoveries of new taxa during explorations of remote parts of Southeast Asia. Many recently published species descriptions of Nepenthes are based entirely upon qualitative morphological information and are not supported by adequate research. Accordingly, the status of many Nepenthes taxa is contested. Evolution within the genus is not well understood, because nuclear and maternally inherited plastid genomes cannot resolve relationships between many species, particularly those that evolved recently through introgression or reticulate evolution. Improvement in our understanding of the systematics and evolution of Nepenthes requires the adoption of ‘best practice’ collection and preservation methods, and the application of quantitative analytical methods for morphological, genetic, and ecological information.

Grayed Hair as an Index of Relative Effective X-Ray Dosage in the House Mouse

1930 ◽  
Vol 64 (691) ◽  
pp. 188-190 ◽  
Author(s):  
Clyde E. Keeler
Keyword(s):  
House Mouse ◽  
X Ray
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