scholarly journals Synthetic DNA and RNA Programming

Genes ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 523
Author(s):  
O’Donoghue ◽  
Heinemann
Keyword(s):  
Synthetic Biology ◽  
Molecular Biology ◽  
Molecular Basis ◽  
Molecular Mechanisms ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Synthetic Dna ◽  
Dna And Rna ◽  
Rna And Dna

Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering as well as omics technologies. Together these technologies have transformed our ability to reveal the biology of the cell and the molecular basis of disease. This Special Issue on “Synthetic RNA and DNA Programming” features original research articles and reviews, highlighting novel aspects of basic molecular biology and the molecular mechanisms of disease that were uncovered by the application and development of novel synthetic biology-driven approaches.

scholarly journals Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants

2021 ◽  
Vol 22 (11) ◽  
pp. 6080
Author(s):  
Víctor Quesada
Keyword(s):  
Abscisic Acid ◽  
Molecular Mechanisms ◽  
Original Research ◽  
Special Issue ◽  
Research Papers

In this special issue entitled, “Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants”, eight articles are collected, with five reviews and three original research papers, which broadly cover different topics on the abscisic acid (ABA) field and, to a lesser extent, on gibberellins (GAs) research [...]

scholarly journals Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise

Genes ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 1043
Author(s):  
Italia Di Liegro
Keyword(s):  
Physical Exercise ◽  
Cognitive Processes ◽  
Sedentary Lifestyle ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Cell Functions ◽  
Ancient Times ◽  
Epigenetic Modulation ◽  
Molecular Bases

Since ancient times, the importance of physical activity (PA) and of a wholesome diet for human health has been clearly recognized. However, only recently, it has been acknowledged that PA can reverse at least some of the unwanted effects of a sedentary lifestyle, contributing to the treatment of pathologies such as hypertension and diabetes, to the delay of aging and neurodegeneration, and even to the improvement of immunity and cognitive processes. At the same time, the cellular and molecular bases of these effects are beginning to be uncovered. The original research articles and reviews published in this Special Issue on “Genetic and Epigenetic Modulation of Cell Functions by Physical Exercise” focus on different aspects of the genetics and molecular biology of PA effects on health and, in addition, on the effects of different genotypes on the ability to perform PA. All authors have read and agreed to the published version of the manuscript.

scholarly journals Synthetic Biology Open Language (SBOL) Version 2.1.0

2016 ◽  
Vol 13 (3) ◽  
Author(s):  
Jacob Beal ◽  
Robert Sidney Cox ◽  
Raik Grünberg ◽  
James McLaughlin ◽  
Tramy Nguyen ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Synthetic Biology ◽  
Molecular Biology ◽  
Best Practices ◽  
Basic Sequence ◽  
Special Issue ◽  
Biological Design ◽  
Version 2.0 ◽  
Topology Information ◽  
Synthetic Biology Open Language

SummarySynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.1 of SBOL that builds upon version 2.0 published in last year’s JIB special issue. In particular, SBOL 2.1 includes improved rules for what constitutes a valid SBOL document, new role fields to simplify the expression of sequence features and how components are used in context, and new best practices descriptions to improve the exchange of basic sequence topology information and the description of genetic design provenance, as well as miscellaneous other minor improvements.

scholarly journals Embryo–Maternal Interactions Underlying Reproduction in Mammals

2020 ◽  
Vol 21 (14) ◽  
pp. 4872
Author(s):  
Stefan Bauersachs ◽  
Carmen Almiñana
Keyword(s):  
Current Knowledge ◽  
Mammalian Species ◽  
Stress Factors ◽  
Research Articles ◽  
Future Research ◽  
Original Research ◽  
Special Issue ◽  
New Findings ◽  
As Stress ◽  
The Impact

This Special Issue, “Embryo-Maternal Interactions Underlying Reproduction in Mammals”, gathers a collection of 23 articles, 16 original research articles and 7 up-to-date reviews, providing new findings or summarizing current knowledge on embryo–maternal interactions in seven different mammalian species including humans. Considering the different players involved in these embryo-maternal interactions, articles are mainly focused on one of these different players: the oviduct, the uterus, the embryo or the emergent extracellular vesicles. Additionally, a few articles bring up the impact of reproductive, but also non-reproductive, diseases, as well as stress factors, on the establishment of pregnancy. We hope the readers enjoy this collection of articles and that the knowledge assembled here will support and inspire current and future research investigations. We would like to thank all authors for their contributions to this Special Issue.

scholarly journals Multifunctional Nanomaterials: Synthesis, Properties and Applications

2021 ◽  
Vol 22 (21) ◽  
pp. 12073
Author(s):  
Raghvendra Singh Yadav
Keyword(s):  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Synthesis Properties ◽  
Nanomaterials Synthesis ◽  
Multifunctional Nanomaterials

In this Special Issue “Multifunctional Nanomaterials: Synthesis, Properties and Applications”, we published three review papers and nine original research articles [...]

scholarly journals Epileptic Seizures in Critically Ill Patients: Diagnosis, Management, and Outcomes

2020 ◽  
Vol 9 (7) ◽  
pp. 2218 ◽  
Author(s):  
Mathilde Holleville ◽  
Gwenaëlle Jacq ◽  
François Perier ◽  
Candice Fontaine ◽  
Stephane Legriel
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Epileptic Seizures ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Mortality And Morbidity ◽  
Global Epidemiology ◽  
High Degree ◽  
Significant Mortality

Epileptic seizures in critically ill patients represent a major source of concern, because they are associated with significant mortality and morbidity rates. Despite recent advances that have enabled a better understanding of the global epidemiology of this entity, epileptic seizures in critically ill patients remain associated with a high degree of uncertainty and numerous questions remain unanswered. The present Special Issue aims to invite authors to contribute original research articles as well as review articles related to all aspects of epileptic seizures in critically ill patients, diagnosis, management, and outcomes.

scholarly journals Novel Aspects of Toxicity Mechanisms of Dioxins and Related Compounds

2020 ◽  
Vol 21 (7) ◽  
pp. 2342 ◽  
Author(s):  
Raimo Pohjanvirta ◽  
Matti Viluksela
Keyword(s):  
Developmental Toxicity ◽  
Environmental Contaminants ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Aryl Hydrocarbon ◽  
Low Toxicity ◽  
Toxicity Mechanisms ◽  
Dioxin Toxicity ◽  
Related Compounds

Dioxins and related compounds are common environmental contaminants. Although their levels have gone down, they are still of concern, in particular regarding developmental toxicity. The adverse effects of these compounds are mediated by the aryl hydrocarbon receptor (AHR), whose canonical signaling pathway has been unveiled in fair detail. The alternative (non-genomic) pathways are much more obscure. AHR has also proven to be a master regulator of numerous physiological phenomena, which has led to the search of selective AHR modulators with low toxicity. Papers of this Special Issue address the developmental toxicity of dioxins and related compounds as well as selective modulators of AHR and both its canonical and alternative signaling pathways. In addition, new optical and stereoscopic methods for the detection of dioxins are presented. As a whole, this Special Issue provides an up-to-date view on a wide variety of aspects related to dioxin toxicity mechanisms from both original research articles and reviews.

Landscape Below Ground IV: Introduction to a Special Issue

2019 ◽  
Vol 45 (6) ◽  
Author(s):  
Gary Watson
Keyword(s):  
Root Systems ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Below Ground ◽  
Care Practices ◽  
Tree Care

This special issue is dedicated to research presented at the 2018 Landscape Below Ground IV conference. We describe highlights from the ten original research articles included in this issue. With these articles, we aim to support the advancement of tree care practices and inform managers and policymakers to choose, site, plant, and care for healthier, longer-lived trees by focusing on their critical and vulnerable root systems and the soil that surrounds them.

scholarly journals Synthetic Biology Open Language (SBOL) Version 2.3

2019 ◽  
Vol 16 (2) ◽  
Author(s):  
Curtis Madsen ◽  
Angel Goñi Moreno ◽  
Umesh P ◽  
Zachary Palchick ◽  
Nicholas Roehner ◽  
...  
Keyword(s):  
Experimental Data ◽  
Metabolic Engineering ◽  
Systems Biology ◽  
Synthetic Biology ◽  
Molecular Biology ◽  
Special Issue ◽  
Design Elements ◽  
Biological Design ◽  
Support Organization ◽  
Synthetic Biology Open Language

AbstractSynthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems is to improve the exchange of information about designed systems between laboratories. The synthetic biology open language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.3.0 of SBOL, which builds upon version 2.2.0 published in last year’s JIB Standards in Systems Biology special issue. In particular, SBOL 2.3.0 includes means of succinctly representing sequence modifications, such as insertion, deletion, and replacement, an extension to support organization and attachment of experimental data derived from designs, and an extension for describing numerical parameters of design elements. The new version also includes specifying types of synthetic biology activities, unambiguous locations for sequences with multiple encodings, refinement of a number of validation rules, improved figures and examples, and clarification on a number of issues related to the use of external ontology terms.

scholarly journals Dietary Anthocyanins and Human Health

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2107 ◽  
Author(s):  
Christopher N. Blesso
Keyword(s):  
Chronic Disease ◽  
Antioxidant Status ◽  
Inverse Relationship ◽  
Vegetable Intake ◽  
Mechanisms Of Action ◽  
Fruit And Vegetable Intake ◽  
Research Articles ◽  
Original Research ◽  
Special Issue ◽  
Underlying Mechanisms

Anthocyanins may contribute to the inverse relationship between fruit and vegetable intake and chronic disease. Anthocyanins are pigments found in plant structures that consist of an anthocyanidin (aglycone) attached to sugar moieties. Anthocyanins may be beneficial for health through effects on cellular antioxidant status and inflammation; however, their underlying mechanisms of action in their protection of chronic diseases are likely complex and require further elucidation. This Special Issue comprises 8 peer-reviewed papers (including 6 original research articles) which highlight the diverse bioactivities of anthocyanins and anthocyanin-rich foods in the protection against chronic disease.

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