scholarly journals A Hybrid Continuum-Particle Approach for Fluid-Structure Interaction Simulation of Red Blood Cells in Fluid Flows

Fluids ◽  
2021 ◽  
Vol 6 (4) ◽  
pp. 139
Author(s):  
Lahcen Akerkouch ◽  
Trung Bao Le
Keyword(s):  
Fluid Flow ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Fluid Structure Interaction ◽  
Fluid Flows ◽  
Accurate Estimation ◽  
Cellular Dynamics ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Particle Approach

Transport of cells in fluid flow plays a critical role in many physiological processes of the human body. Recent developments of in vitro techniques have enabled the understanding of cellular dynamics in laboratory conditions. However, it is challenging to obtain precise characteristics of cellular dynamics using experimental method alone, especially under in vivo conditions. This challenge motivates new developments of computational methods to provide complementary data that experimental techniques are not able to provide. Since there exists a large disparity in spatial and temporal scales in this problem, which requires a large number of cells to be simulated, it is highly desirable to develop an efficient numerical method for the interaction of cells and fluid flows. In this work, a new Fluid-Structure Interaction formulation is proposed based on the use of hybrid continuum-particle approach, which can resolve local dynamics of cells while providing large-scale flow patterns in the vascular vessel. Here, the Dissipative Particle Dynamics (DPD) model for the cellular membrane is used in conjunction with the Immersed Boundary Method (IBM) for the fluid plasma. Our results show that the new formulation is highly efficient in computing the deformation of cells within fluid flow while satisfying the incompressibility constraints of the fluid. We demonstrate that it is possible to couple the DPD with the IBM to simulate the complex dynamics of Red Blood Cells (RBC) such as parachuting. Our key observation is that the proposed coupling enables the simulation of RBC dynamics in realistic arterioles while ensuring the incompressibility constraint for fluid plasma. Therefore, the proposed method allows an accurate estimation of fluid shear stresses on the surface of simulated RBC. Our results suggest that this hybrid methodology can be extended for a variety of cells in physiological conditions.

Fluid–Structure Interaction of High Aspect-Ratio Hair-Like Micro-Structures Through Dimensional Transformation Using Lattice Boltzmann Method

2016 ◽  
Vol 08 (08) ◽  
pp. 1650095 ◽  
Author(s):  
H. Devaraj ◽  
Kean C. Aw ◽  
E. Haemmerle ◽  
R. Sharma
Keyword(s):  
Fluid Flow ◽  
Drag Force ◽  
Lattice Boltzmann ◽  
Stokes Equations ◽  
Fluid Structure Interaction ◽  
Structural Response ◽  
Momentum Exchange ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Micro Structures

3D printed hair-like micro-structures have been previously demonstrated in a novel micro-fluidic flow sensor aimed at sensing air flows down to rates of a few milliliters per second. However, there is a lack of in-depth understanding of the structural response of these ‘micro-hairs' under a fluid flow field. This paper demonstrates the use of lattice Boltzmann methods (LBM) to understand this structural response towards a better optimization of the micro-hair flow sensors designed to suit the end applications' needs. The LBM approach was chosen as an efficient alternative to simulate Navier–Stokes equations for modeling fluid flow around complex geometries primarily for improved accuracy and simplicity with lesser computational costs. As the spatial dimensions of the sensor's flow channel are much larger in comparison to the actual micro-hairs (the sensing element), a multidimensional approach of combining two-dimensional (D2Q9) and three-dimensional (D3Q19) lattice configurations were implemented for improved computational speeds and efficiency. The drag force on the micro-hairs was estimated using the momentum-exchange method in the D3Q19 configuration and this drag force is transferred to the structural analysis model which determines the micro-hair deformation using Euler–Bernoulli beam theory. The entirety of the LBM Fluid–Structure Interaction (FSI) model was implemented within MATLAB and the obtained results are compared against the numerical model implemented on a commercially available software package.

Fluid-Structure Interaction Approach for Numerical Investigation of a Flexible Hydrofoil Deformations in Turbulent Fluid Flow

2018 ◽  
Author(s):  
M. Benaouicha ◽  
S. Guillou ◽  
A. Santa Cruz ◽  
H. Trigui
Keyword(s):  
Fluid Flow ◽  
Numerical Model ◽  
Stokes Equations ◽  
Fluid Structure Interaction ◽  
Time Step ◽  
Fluid Structure ◽  
Turbulent Fluid Flow ◽  
Turbulent Fluid ◽  
Structure Interaction ◽  
Ale Formulation

The study deals with a 3D Fluid-Structure Interaction (FSI) numerical model of a rectangular cantilevered flexible hydrofoil subjected to a turbulent fluid flow regime. The structural response and dynamic deformations are studied by analyzing the oscillations frequencies and amplitudes, under a hydrodynamics loads. The obtained numerical results are confronted with experimental ones, for validation. The numerical model is performed in the same geometric, physical and material conditions as the experimental set-up carried out in a hydrodynamic tunnel. A polyacetal (POM) flexible hydrofoil NACA0015 with an angle of attack of 8° is considered to be immersed in a fluid flow at a Reynold number of 3 × 105. The structure is initially at rest and then moved by the action of the fluid flow. The numerical model is based on a strong coupling procedure for solving the Fluid-Structure Interaction problem. The Arbitrary Lagrangian-Eulerian (ALE) formulation of the Navier-Stokes equations is used and an anisotropic diffusion equation is solved to compute the fluid mesh velocity and position at each time step. The finite volume method is used for the numerical resolution of the fluid dynamics equations. The structure deformations are described by the linear elasticity equation which is solved by the finite elements method. The Fluid-Structure coupled problem is solved by using the partitioned FSI implicit algorithm. A good agreement between numerical and experimental results for the hydrodynamics coefficients and hydrofoil deformations, maximum deflection and frequencies is obtained. The added mass and damping are analyzed and then the FSI effect on the dynamic deformations of the structure is highlighted.

scholarly journals Estimation of Loading-Driven Fluid-Flow Pattern in Lacunar-Canalicular Space Using Fluid Structure Interaction

2020 ◽  
Vol 1504 ◽  
pp. 012006
Author(s):  
Rakesh Kumar ◽  
Salil Khana ◽  
Abhishek Kumar Tiwari ◽  
Dharmendra Tripathi ◽  
Niti Nipun Sharma
Keyword(s):  
Fluid Flow ◽  
Flow Pattern ◽  
Fluid Structure Interaction ◽  
Fluid Structure ◽  
Structure Interaction
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