scholarly journals Experimental and Numerical Study of Blood Flow in μ-vessels: Influence of the Fahraeus–Lindqvist Effect

Fluids ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 143
Author(s):  
Yorgos G. Stergiou ◽  
Aggelos T. Keramydas ◽  
Antonios D. Anastasiou ◽  
Aikaterini A. Mouza ◽  
Spiros V. Paras
Keyword(s):  
Blood Flow ◽  
Axial Velocity ◽  
Particle Image ◽  
Numerical Study ◽  
Implantable Devices ◽  
Cfd Simulations ◽  
Micro Particle Image Velocimetry ◽  
Image Velocimetry ◽  
Computational Fluid Dynamics Cfd ◽  
Cell Free Layer

The study of hemodynamics is particularly important in medicine and biomedical engineering as it is crucial for the design of new implantable devices and for understanding the mechanism of various diseases related to blood flow. In this study, we experimentally identify the cell free layer (CFL) width, which is the result of the Fahraeus–Lindqvist effect, as well as the axial velocity distribution of blood flow in microvessels. The CFL extent was determined using microscopic photography, while the blood velocity was measured by micro-particle image velocimetry (μ-PIV). Based on the experimental results, we formulated a correlation for the prediction of the CFL width in small caliber (D < 300 μm) vessels as a function of a modified Reynolds number (Re∞) and the hematocrit (Hct). This correlation along with the lateral distribution of blood viscosity were used as input to a “two-regions” computational model. The reliability of the code was checked by comparing the experimentally obtained axial velocity profiles with those calculated by the computational fluid dynamics (CFD) simulations. We propose a methodology for calculating the friction loses during blood flow in μ-vessels, where the Fahraeus–Lindqvist effect plays a prominent role, and show that the pressure drop may be overestimated by 80% to 150% if the CFL is neglected.

Experimental and Numerical Flow Visualization in Patient Specific Pre Operative Human Airway Geometry

2011 ◽  
Author(s):  
Mathias Vermeulen ◽  
Cedric Van Holsbeke ◽  
Tom Claessens ◽  
Jan De Backer ◽  
Peter Van Ransbeeck ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Particle Image ◽  
Patient Specific ◽  
Lung Volume Reduction ◽  
Cfd Simulations ◽  
Piv Measurements ◽  
Image Velocimetry ◽  
Specific Geometry ◽  
Computational Fluid Dynamics Cfd ◽  
Human Airways

An experimental and numerical platform was developed to investigate the fluidodynamics in human airways. A pre operative patient specific geometry was used to create an identical experimental and numerical model. The experimental results obtained from Particle Image Velocimetry (PIV) measurements were compared to Computational Fluid Dynamics (CFD) simulations under stationary and pulsatile flow regimes. Together these results constitute the first step in predicting the clinical outcome of patients after lung surgeries such as Lung Volume Reduction.

Experimental and Numerical Study of the Flow Around a Semi-Submerged Rectangular Cylinder

2012 ◽  
Author(s):  
Tufan Arslan ◽  
Stefano Malavasi ◽  
Bjørnar Pettersen ◽  
Helge I. Andersson
Keyword(s):  
Particle Image ◽  
Model Simulation ◽  
Numerical Study ◽  
Three Dimensional ◽  
Separated Flow ◽  
Piv Measurements ◽  
Rectangular Cylinder ◽  
Image Velocimetry ◽  
Computational Fluid Dynamics Cfd

The present work is motivated by phenomena occurring in the flow field around structures partly submerged in water. A three dimensional unsteady flow around a rectangular cylinder is studied for four different submergence ratios by using computational fluid dynamics (CFD) tools with LES turbulence model. Simulation results are compared to particle image velocimetry (PIV) measurements at Reynolds number Re = 12100 and Froude number Fr = 0.26. Focus in our investigation is on the characterization of the behaviour of vortex structures generated by separated flow. Another target in the study is to obtain better knowledge of the hydrodynamic forces acting on a semi-submerged structure. Computed force coefficients are compared with experimental measurements.

scholarly journals Experimental Study on the Influence of Bulbous Bow Form on the Velocity Field around the Bow of a Trimaran Using Towed Underwater 2D-3C SPIV

2021 ◽  
Vol 9 (8) ◽  
pp. 905
Author(s):  
Rui Deng ◽  
Shigang Wang ◽  
Wanzhen Luo ◽  
Tiecheng Wu
Keyword(s):  
Particle Image Velocimetry ◽  
Flow Field ◽  
Axial Velocity ◽  
Particle Image ◽  
Stereoscopic Particle Image Velocimetry ◽  
Testing Model ◽  
Image Velocimetry ◽  
Measured Flow ◽  
Computational Fluid Dynamics Cfd ◽  
Bulbous Bow

In this study, particle image velocimetry was applied to measure the flow field around the bow region of a trimaran with different appendages. The dimensionless axial velocity u/U in test planes 1 and 2 of the testing model was measured by using a towed underwater stereoscopic particle image velocimetry (SPIV) system. Based on the measured flow field data, the local sinkage values in test planes 1 and 2 of the testing model with different appendages at speeds of 1.766 and 2.943 m/s were presented. In addition, the effects of speed, bulbous bow type, T foils, and bow wave on the axial velocity u/U were studied in detail. The acquired experimental data help in understanding the distribution of the flow field around the ship bow, and the data can also act as a reference to verify computational fluid dynamics (CFD) results.

Micro Particle Image Velocimetry and Numerical Investigation of Micro Couette Blood Flow

2012 ◽  
Author(s):  
R. Mehri ◽  
C. Mavriplis ◽  
M. Fenech
Keyword(s):  
Blood Flow ◽  
Particle Image Velocimetry ◽  
Shear Rate ◽  
Particle Image ◽  
Velocity Ratio ◽  
Aggregate Size ◽  
Particle Image Velocimetry System ◽  
Micro Particle Image Velocimetry ◽  
Image Velocimetry ◽  
Rbc Aggregation

The purpose of the work presented this paper is to design a model to study experimentally and numerically a micro-Couette blood flow to obtain a constant and controlled shear rate that is a suitable environment for analysis of Red Blood Cell (RBC) aggregation. Due to the simplicity of the flow conditions, aggregate size can be related to the constant shear rate applied. This Couette flow is created by the motion of a second fluid that entrains the blood. The experimental work is coupled with 3D numerical simulations performed using a research computational fluid dynamics solver, Nek5000, based on the spectral element method, while the experiments are conducted using a micro-particle image velocimetry system. Two models of microchannels, with different dimensions, 150 × 33μm and 170 × 64μm, are fabricated in the laboratory using standard photolithography methods. The design of the channel is based on several parameters determined by the simulations. A Newtonian model is tested numerically and experimentally. Blood is then tested experimentally to be compared to the simulation results. We find that using a velocity ratio of 4 between the two Newtonian fluids, we create a flow where one third of the channel thickness is filled with the fluid destined to be blood. In the blood experiments, the velocity profile in this layer is approximately linear, resulting in the desired controlled conditions for the study of RBC aggregation.

Experimental investigation of the influence of the hydraulic performance of an axial blood pump on intraventricular blood flow

2021 ◽  
pp. 039139882110130
Author(s):  
Guang-Mao Liu ◽  
Fu-Qing Jiang ◽  
Xiao-Han Yang ◽  
Run-Jie Wei ◽  
Sheng-Shou Hu
Keyword(s):  
Blood Flow ◽  
Particle Image ◽  
Swirling Flow ◽  
Blood Stasis ◽  
Systemic Circulation ◽  
Operating Conditions ◽  
Blood Pump ◽  
Image Velocimetry ◽  
Ct Data

Blood flow inside the left ventricle (LV) is a concern for blood pump use and contributes to ventricle suction and thromboembolic events. However, few studies have examined blood flow inside the LV after a blood pump was implanted. In this study, in vitro experiments were conducted to emulate the intraventricular blood flow, such as blood flow velocity, the distribution of streamlines, vorticity and the standard deviation of velocity inside the LV during axial blood pump support. A silicone LV reconstructed from computerized tomography (CT) data of a heart failure patient was incorporated into a mock circulatory loop (MCL) to simulate human systemic circulation. Then, the blood flow inside the ventricle was examined by particle image velocimetry (PIV) equipment. The results showed that the operating conditions of the axial blood pump influenced flow patterns within the LV and areas of potential blood stasis, and the intraventricular swirling flow was altered with blood pump support. The presence of vorticity in the LV from the thoracic aorta to the heart apex can provide thorough washing of the LV cavity. The gradually extending stasis region in the central LV with increasing blood pump support is necessary to reduce the thrombosis potential in the LV.

Flow Characteristics of Pressure-Driven Water in Serpentine Micro-Channels

2006 ◽  
Author(s):  
Renqiang Xiong ◽  
J. N. Chung
Keyword(s):  
Particle Image Velocimetry ◽  
Particle Image ◽  
Flow Characteristics ◽  
Flow Structures ◽  
Micro Channel ◽  
Pressure Drops ◽  
Micro Particle Image Velocimetry ◽  
Image Velocimetry ◽  
Micro Channels ◽  
Shape And Size

Flow structures and pressure drops were investigated in rectangular serpentine micro-channels with miter bends which had hydraulic diameters of 0.209mm, 0.395mm and 0.549mm respectively. To evaluate the bend effect, the additional pressure drop due to the miter bend must be obtained. Three groups of micro-channels were fabricated to remove the inlet and outlet losses. A validated micro-particle image velocimetry (μPIV) system was used to achieve the flow structure in a serpentine micro-channel with hydraulic diameter of 0.173mm. The experimental results show the vortices around the outer and inner walls of the bend do not form when Re&lt;100. Those vortices appear and continue to develop with the Re number when Re&gt; 100-300, and the shape and size of the vortices almost remain constant when Re&gt;1000. The bend loss coefficient Kb was observed to be related with the Re number when Re&lt;100, with the Re number and channel size when Re&gt;100. It almost keeps constant and changes in the range of ± 10% When Re is larger than some value in 1300-1500. And a size effect on Kb was also observed.

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