scholarly journals Comparison of Series Compensation Topologies for Inductive Chargers of Biomedical Implantable Devices

Electronics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 8 ◽  
Author(s):  
Eleni Gati ◽  
Sotirios Kokosis ◽  
Nikolaos Patsourakis ◽  
Stefanos Manias
Keyword(s):  
Experimental Evaluation ◽  
Biomedical Applications ◽  
Implantable Devices ◽  
Extensive Investigation ◽  
Key Factors ◽  
Series Compensation ◽  
Frequency Selection ◽  
Medical Issues ◽  
Custom Made ◽  
Secondary Side

Modern biomedical implantable devices provide an increasingly popular solution for health monitoring and medical issues. Their level of development in the coming years will depend on their reliability and endurance. Their powering and recharging capabilities are key factors for their dominance. In this work, series compensation topologies for use in inductive chargers of biomedical implantable devices are investigated with regard to their performance. The goal is to assess the possibility of reducing the component count of the implantable device and thus, increase its reliability and patient safety. Comparison is performed between the commonly used series-series compensation topology with a topology which incorporates no capacitors in the secondary side but only series compensation in the primary. Extensive investigation of the operation of the two topologies is made through mathematical analysis, simulations, and experimental evaluation, for the most popular schemes of operation, with regard to frequency selection. A prototype inductive charger, including a custom-made inductive link, was designed and built for the experimental evaluation of the system. Insights on the operation of both topologies are provided and the results show that primary-side series compensation can be a strong alternative to series-series compensation, in biomedical applications.

Aerogels for Biomedical Applications

2021 ◽  
pp. 23-42
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Bone Regeneration ◽  
Biomedical Applications ◽  
Implantable Devices ◽  
Strategic Development ◽  
The World ◽  
Biomedical Field ◽  
Materials Used

The researchers across the world are actively engaged in strategic development of new porous aerogel materials for possible application of these extraordinary materials in the biomedical field. Due to their excellent porosity and established biocompatibility, aerogels are now emerging as viable solutions for drug delivery and other biomedical applications. This chapter aims to cover the diverse aerogel materials used across the globe for different biomedical applications including drug delivery, implantable devices, regenerative medicine encompassing tissue engineering and bone regeneration, and biosensing.

scholarly journals Cumulative Effects of Ultraviolet Radiation and Photosyntheically Active Radiation on Phycobiliproteins of A Hot-Spring Cyanobacatrium Nostoc sp. strain HKAR-2

2016 ◽  
Vol 4 (3) ◽  
pp. 247-253
Author(s):  
Vinod K. Kannaujiya ◽  
Akhlaqur Rahman ◽  
. Adinath ◽  
Arun S. Sonker ◽  
Jainendra Pathak ◽  
...  
Keyword(s):  
Ultraviolet Radiation ◽  
Environmental Conditions ◽  
Photosynthetically Active Radiation ◽  
Biomedical Applications ◽  
Hot Spring ◽  
Ultraviolet B ◽  
Cumulative Effects ◽  
Key Factors ◽  
Active Radiation ◽  
Continuous Induction

Cyanobacteria are cosmopolitan in distribution and have adapted to diverse habitats. Adaptation of cyanobacteria is one of the key factors to withstand harsh environmental conditions. We have investigated the effects of photosynthetically active radiation (PAR; 400–700 nm), ultraviolet-B (UV-B; 280–315 nm) radiation and PAR+UV-B radiations on phycobiliproteins (PBPs) of a hot-spring cyanobacterium Nostoc sp. HKAR-2. There was a continuous induction of both phycoerythrin (PE) and phycocyanin (PC) after exposure of PAR up to 300 min. However, there was an induction in the synthesis of both PE and PC up to 240 min exposure of UV-B and PAR+UV-B radiations. Further exposure showed decline in the synthesis due to rapid uncoupling, bleaching and degradation of PBPs. Similarly, emission fluorescence also showed an induction with a shift towards longer wavelengths after 240 min of UV-B and PAR+UV-B exposure. These results indicate that short duration of UV radiation may promote the synthesis of PBPs that can be utilized in various biotechnological and biomedical applications. Int J Appl Sci Biotechnol, Vol 4(3): 247-253

scholarly journals Alginic Acid Polymer-Hydroxyapatite Composites for Bone Tissue Engineering

Polymers ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 3070
Author(s):  
Rebecca Sikkema ◽  
Blanca Keohan ◽  
Igor Zhitomirsky
Keyword(s):  
Biomedical Applications ◽  
Antimicrobial Agents ◽  
Alginic Acid ◽  
Functional Materials ◽  
Key Factors ◽  
Advanced Composite ◽  
Dispersing Agent ◽  
Film Forming ◽  
Manufacturing Techniques ◽  
Electrochemical Fabrication

Natural bone is a composite organic-inorganic material, containing hydroxyapatite (HAP) as an inorganic phase. In this review, applications of natural alginic acid (ALGH) polymer for the fabrication of composites containing HAP are described. ALGH is used as a biocompatible structure directing, capping and dispersing agent for the synthesis of HAP. Many advanced techniques for the fabrication of ALGH-HAP composites are attributed to the ability of ALGH to promote biomineralization. Gel-forming and film-forming properties of ALGH are key factors for the development of colloidal manufacturing techniques. Electrochemical fabrication techniques are based on strong ALGH adsorption on HAP, pH-dependent charge and solubility of ALGH. Functional properties of advanced composite ALGH-HAP films and coatings, scaffolds, biocements, gels and beads are described. The composites are loaded with other functional materials, such as antimicrobial agents, drugs, proteins and enzymes. Moreover, the composites provided a platform for their loading with cells for the fabrication of composites with enhanced properties for various biomedical applications. This review summarizes manufacturing strategies, mechanisms and outlines future trends in the development of functional biocomposites.

SiC for Biomedical Applications

2016 ◽  
Vol 858 ◽  
pp. 1010-1014 ◽  
Author(s):  
Stephen E. Saddow ◽  
Christopher L. Frewin ◽  
Fabiola Araujo Cespedes ◽  
Marioa Gazziro ◽  
Evans Bernadin ◽  
...  
Keyword(s):  
Silicon Carbide ◽  
Biomedical Applications ◽  
Glucose Monitoring ◽  
Wide Band ◽  
Neural Interfaces ◽  
Free Standing ◽  
Wide Band Gap ◽  
Custom Made ◽  
Biological World ◽  
Machine Interface

Silicon carbide is a well-known wide-band gap semiconductor traditionally used in power electronics and solid-state lighting due to its extremely low intrinsic carrier concentration and high thermal conductivity. What is only recently being discovered is that it possesses excellent compatibility within the biological world. Since publication of the first edition of Silicon Carbide Biotechnology: A Biocompatible Semiconductor for Advanced Biomedical Devices and Applications five years ago [1], significant progress has been made on numerous research and development fronts. In this paper three very promising developments are briefly highlighted – progress towards the realization of a continuous glucose monitoring system, implantable neural interfaces made from free-standing 3C-SiC, and a custom-made low-power ‘wireless capable’ four channel neural recording chip for brain-machine interface applications.

Study on a hydrophobic Ti-doped hydroxyapatite coating for corrosion protection of a titanium based alloy

RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87665-87674 ◽  
Author(s):  
M. A. Surmeneva ◽  
A. Vladescu ◽  
R. A. Surmenev ◽  
C. M. Pantilimon ◽  
M. Braic ◽  
...  
Keyword(s):  
Corrosion Protection ◽  
Direct Contact ◽  
Biomedical Applications ◽  
Implantable Devices ◽  
Hydroxyapatite Coating ◽  
Hydroxyapatite Coatings

In the paper, hydroxyapatite coatings enriched with Ti were prepared as a possible candidate for biomedical applications, especially for implantable devices that are in direct contact with bone.

scholarly journals On the evaluation of photogrammetric methods for dense 3D surface reconstruction in a metrological context

2014 ◽  
Vol II-5 ◽  
pp. 371-378 ◽  
Author(s):  
I. Toschi ◽  
A. Capra ◽  
L. De Luca ◽  
J.-A. Beraldin ◽  
L. Cournoyer
Keyword(s):  
3D Imaging ◽  
National Research Council ◽  
Point Clouds ◽  
Key Factors ◽  
Factors Affecting ◽  
Market Growth ◽  
3D Point Clouds ◽  
Custom Made ◽  
Modelling Techniques ◽  
Definition Of

This paper discusses a methodology to evaluate the accuracy of recently developed image-based 3D modelling techniques. So far, the emergence of these novel methods has not been supported by the definition of an internationally recognized standard which is fundamental for user confidence and market growth. In order to provide an element of reflection and solution to the different communities involved in 3D imaging, a promising approach is presented in this paper for the assessment of both metric quality and limitations of an open-source suite of tools (Apero/MicMac), developed for the extraction of dense 3D point clouds from a set of unordered 2D images. The proposed procedural workflow is performed within a metrological context, through inter-comparisons with "reference" data acquired with two hemispherical laser scanners, one total station, and one laser tracker. The methodology is applied to two case studies, designed in order to analyse the software performances in dealing with both outdoor and environmentally controlled conditions, i.e. the main entrance of Cathédrale de la Major (Marseille, France) and a custom-made scene located at National Research Council of Canada 3D imaging Metrology Laboratory (Ottawa). Comparative data and accuracy evidence produced for both tests allow the study of some key factors affecting 3D model accuracy.

scholarly journals Nanoparticles and their Biomedical Applications

2020 ◽  
Vol 11 (1) ◽  
pp. 8431-8445
Keyword(s):  
Plant Extracts ◽  
Biomedical Applications ◽  
Room Temperature ◽  
Cost Effective ◽  
Reduction Reaction ◽  
Key Factors ◽  
Physical Chemical ◽  
Biological Methods ◽  
Treatment And Diagnosis ◽  
Diagnosis Of Diseases

Over the years, due to the remarkable functional properties, the nanoparticles have been widely used and being tested in the treatment and diagnosis of diseases such as cancer, diabetes, etc. The green synthesis of these nanoparticles can be achieved by physical, chemical, and biological methods. Nanoparticles biosynthesis is put forth to be advantageous over chemical and physical methods because it is non or minimally toxic, environmentally friendly, and cost-effective. A green biosynthesis is an approach that connects nanotechnology with plants, microorganisms, waste materials, and biomolecules. The biological methods help to eliminate destructive processing situations, via letting the synthesis at biological pH, room temperature, and simultaneously, affordable price. Among various biological alternatives, medicinal plants and plant extracts seem to be the best options. Plants are the chemical factories of nature, the plant extracts contain various secondary metabolites, and it functions as reducing and stabilizing (capping) agent in bio-reduction reaction to synthesize new nanoparticles. Keeping these points in view, the present article reviews the various synthesis methodologies, key factors, characterizations, usages, and foretold antimicrobial approach in a systematic manner, concentrating on several green pathways for nanoparticles synthesis.

Design and Development of Antibody Functionalized Gold Nanoparticles for Biomedical Applications

2021 ◽  
Vol 21 (5) ◽  
pp. 2834-2840
Author(s):  
José M. Abad ◽  
Sara Puertas ◽  
Daniel Pérez ◽  
Christian Sánchez-Espinel
Keyword(s):  
Gold Nanoparticles ◽  
Metal Binding ◽  
Biomedical Applications ◽  
Antibody Immobilization ◽  
Metal Chelation ◽  
Igg Antibodies ◽  
Key Factors ◽  
Functionalized Gold Nanoparticles ◽  
Oriented Immobilization ◽  
Insight Into

Antibody-functionalized gold nanoparticle constitutes a powerful interface biosystem for biomedical applications where the properties of gold nanoparticles and the specificity of antibody–antigen interactions are combined. This study provides insight into the key factors for the development of antibody functionalized gold nanoparticles focusing on the immobilization of the antibody. Here, we address an oriented antibody immobilization procedure on gold nanoparticles. It comprises chelatemodified gold nanoparticles that are designed for oriented immobilization of IgG antibodies (end on spatial orientation) through the metal-chelation to histidine-rich metal binding site in the heavy chain (Fc) of the antibody.

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