scholarly journals Microfluidic Sensor Based on Composite Left-Right Handed Transmission Line

Electronics ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 1475 ◽  
Author(s):  
Vasa Radonić ◽  
Slobodan Birgermajer ◽  
Ivana Podunavac ◽  
Mila Djisalov ◽  
Ivana Gadjanski ◽  
...  
Keyword(s):  
Phase Shift ◽  
Transmission Lines ◽  
Electromagnetic Waves ◽  
Microstrip Line ◽  
Effective Permittivity ◽  
Ground Plane ◽  
High Sensitivity ◽  
Biomass Estimation ◽  
Shift Measurement ◽  
The Right

In this paper, we propose a novel metamaterial-based microfluidic sensor that permits the monitoring of properties of the fluid flowing in the microfluidic reservoir embedded between the composite left–right handed (CLRH) microstrip line and the ground plane. The sensor’s working principle is based on the phase shift measurement of the two signals, the referent one that is guided through conventional microstrip line and measurement signal guided through the CLRH line. At the operating frequency of 1.275 GHz, the CLRH line supports electromagnetic waves with group and phase velocities that are antiparallel, and therefore the phase “advance” occurs in the case of CLRH line, while phase delay arises in the right-handed (RH) frequency band. The change of the fluid’s properties that flow in the microfluidic reservoir causes the change of effective permittivity of the microstrip substrate, and subsequently the phase velocity changes, as well as the phase shift. This effect was used in the design of the microfluidic sensor for the measurement of characteristics of the fluid that flows in the microfluidic reservoir placed under the CLRH line. The complete measurement system was developed including the Wilkinson power divider that splits the signal between conventional RH and CLRH section, transmission lines with the microfluidic reservoirs, and a detection circuit for phase shift measurement. Measurement results for different fluids confirm that the proposed sensor is characterized by relatively high sensitivity and good linearity (R2 = 0.94). In this study, the practical application of the proposed sensor is demonstrated for the biomass estimation inside the microfluidic bioreactors, which are used for the cultivation of MRC-5 fibroblasts.

Observation of surface morphology by reflection electron holography

1989 ◽  
Vol 47 ◽  
pp. 536-537
Author(s):  
N. Osakabe ◽  
J. Endo ◽  
T. Matsuda ◽  
A. Tonomura
Keyword(s):  
Phase Shift ◽  
Surface Morphology ◽  
High Sensitivity ◽  
High Energy ◽  
Path Difference ◽  
Transmission Mode ◽  
Electron Holography ◽  
Dynamical Process ◽  
High Vertical Resolution ◽  
Amplification Technique

Progress in microscopy such as STM and TEM-TED has revealed surface structures in atomic dimension. REM has been used for the observation of surface dynamical process and surface morphology. Recently developed reflection electron holography, which employes REM optics to measure the phase shift of reflected electron, has been proved to be effective for the observation of surface morphology in high vertical resolution ≃ 0.01 Å.The key to the high sensitivity of the method is best shown by comparing the phase shift generation by surface topography with that in transmission mode. Difference in refractive index between vacuum and material Vo/2E≃10-4 owes the phase shift in transmission mode as shownn Fig. 1( a). While geometrical path difference is created in reflection mode( Fig. 1(b) ), which is measured interferometrically using high energy electron beam of wavelength ≃0.01 Å. Together with the phase amplification technique , the vertivcal resolution is expected to be ≤0.01 Å in an ideal case.

Direct phase-shift measurement of an EUV mask with gradient absorber thickness

2013 ◽  
Author(s):  
Hiroyoshi Tanabe ◽  
Tetsunori Murachi ◽  
Seh-Jin Park ◽  
Eric M. Gullikson ◽  
Tsukasa Abe ◽  
...  
Keyword(s):  
Phase Shift ◽  
Absorber Thickness ◽  
Shift Measurement

Microstrip line on ground plane with closely spaced perforations?fringe fields and formulas by synthetic asymptote

2001 ◽  
Vol 32 (3) ◽  
pp. 201-204 ◽  
Author(s):  
Y. L. Chow ◽  
K. L. Wan ◽  
T. K. Sarkar ◽  
B. Kolundzija
Keyword(s):  
Microstrip Line ◽  
Ground Plane ◽  
Fringe Fields

scholarly journals Application of the Modified Вagolini Test in the Diagnosis of Binocular Vision Disorders

2020 ◽  
Vol 17 (3) ◽  
pp. 435-441
Author(s):  
S. I. Rychkova ◽  
V. G. Likhvantseva
Keyword(s):  
Binocular Vision ◽  
Quantitative Assessment ◽  
Qualitative Evaluation ◽  
High Sensitivity ◽  
Qualitative Assessment ◽  
Control Group ◽  
Color Test ◽  
Functional Correction ◽  
Personalized Approach ◽  
The Right

The work is devoted to one of the most actual problems of current strabismology — the development of effective ways to study binocular vision.The purpose — to study the effectiveness of the developed modification of the Bagolini test in the diagnostics of binocular disorders.Patients and methods. 240 patients with non-paralytic strabismus aged from 6 to 17 (on average 10.8 ± 0.24) years were observed. There were 190 patients with converging strabismus and 50 patients with diverging strabismus. The control group consisted of 180 children aged also from 6 to 17 (on average 10.9 ± 0.3) years without ophthalmopathology. All children were examined for the character of vision using a Worth-test, the classic Bagolini test (CTB), and the developed modified Bagolini test (MTB). If the patient has a strabismus angle, the study was performed in two variants: without prismatic deviation compensation (under the subjective angle of strabismus — SU) and under full prismatic compensation (under the objective angle of strabismus — OU). For qualitative assessment of binocular vision with MTB, static presentation of the test image was used, for quantitative assessment — alternating (alternate presentation of details corresponding to the right and left eyes).Results. The qualitative evaluation data obtained with the help of MTB made it possible to differentiate patients with non-permanent regional functional scotoma of suppression (FSP) and patients with stable bifoveal fusion among children with binocular vision by color test, and to distinguish patients with regional stable FSP and total FSP among children with monocular vision by color test. In the study under SU, the sensitivity of the method was 97.8 % and specificity 96.2 %, under OU — 96.6 % and 92.7 %, correspondingly. Using quantitative evaluation, it was found that the minimum duration of monocular phases required to eliminate functional inhibition in children with total FSP is twice as long as in children with regional FSP (z = 6,303, df 52, p < 0.001 according to the Mann — Whitney criterion).Conclusion. Thus, the modified Bagolini test developed by us is an effective way of qualitative and quantitative assessment of the state of binocular vision. The method has a high sensitivity and specificity, combines the capabilities of anaglyphic and phase haploscopy, and can be used for a personalized approach to the selection of conditions and modes of functional correction of binocular disorders, as well as for monitoring binocular vision during treatment. 

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