scholarly journals Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years

Entropy ◽  
2021 ◽  
Vol 23 (10) ◽  
pp. 1337
Author(s):  
Silvin P. Knight ◽  
Louise Newman ◽  
Siobhan Scarlett ◽  
John D. O’Connor ◽  
James Davis ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cognitive Function ◽  
Cognitive Performance ◽  
Time Series Data ◽  
Community Dwelling ◽  
Short Length ◽  
Series Data ◽  
Longitudinal Waves ◽  
Community Dwelling Older Adults ◽  
State Examination

In this study, the relationship between non-invasively measured cardiovascular signal entropy and global cognitive performance was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study on Ageing (TILDA), both cross-sectionally at baseline (n = 4525; mean (SD) age: 61.9 (8.4) years; 54.1% female) and longitudinally. We hypothesised that signal disorder in the cardiovascular system, as quantified by short-length signal entropy during rest, could provide a marker for cognitive function. Global cognitive function was assessed via Mini Mental State Examination (MMSE) across five longitudinal waves (8 year period; n = 4316; mean (SD) age: 61.9 (8.4) years; 54.4% female) and the Montreal Cognitive Assessment (MOCA) across two longitudinal waves (4 year period; n = 3600; mean (SD) age: 61.7 (8.2) years; 54.1% female). Blood pressure (BP) was continuously monitored during supine rest at baseline, and sample entropy values were calculated for one-minute and five-minute sections of this data, both for time-series data interpolated at 5 Hz and beat-to-beat data. Results revealed significant associations between BP signal entropy and cognitive performance, both cross-sectionally and longitudinally. Results also suggested that as regards associations with cognitive performance, the entropy analysis approach used herein potentially outperformed more traditional cardiovascular measures such as resting heart rate and heart rate variability. The quantification of entropy in short-length BP signals could provide a clinically useful marker of the cardiovascular dysregulations that potentially underlie cognitive decline.

scholarly journals Do Communication Patterns Affect the Association between Cognitive Impairment and Hearing Loss among Older Adults in Vietnam?

2021 ◽  
Vol 18 (4) ◽  
pp. 1603
Author(s):  
Tran Dai Tri Han ◽  
Keiko Nakamura ◽  
Kaoruko Seino ◽  
Vo Nu Hong Duc ◽  
Thang Van Vo
Keyword(s):  
Older Adults ◽  
Hearing Loss ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Vision Loss ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Ordinal Logistic Regression Analysis ◽  
Communication Devices ◽  
Community Dwelling Older Adults

This study examined the prevalence of cognitive impairment among older adults in central Vietnam and the roles of communication (with or without communication devices) in the association between cognitive impairment and hearing loss. This cross-sectional study was performed on 725 randomly selected community-dwelling older adults aged ≥60 years from Thua Thien Hue province, Vietnam. Participants attended a face-to-face survey. Sociodemographic characteristics, social interaction with or without communication devices, health status and cognitive function using the Mini-Mental State Examination were reported. Ordinal logistic regression analysis was performed to quantify the association between hearing loss and cognitive function by frequency of communication with and without devices. Mild and severe cognitive impairment had prevalence rates of 23.6% and 19.3%, respectively. Cognitive impairment was more prevalent among older adults with hearing-loss, vision loss and difficulties with instrumental activities of daily living (IADL). The association between hearing loss and cognitive impairment was not significant when older adults had frequent communication with others using devices. This study presented the relatively high prevalence of cognitive impairment in community-dwelling older adults in Vietnam. Frequent communication using devices attenuated the association between hearing loss and cognitive impairment.

Accelerated Epigenetic Age in Normal Cognitive Aging of Korean Community-Dwelling Older Adults

2021 ◽  
pp. 109980042098389
Author(s):  
Jongmin Park ◽  
Chang Won Won ◽  
Leorey N. Saligan ◽  
Youn-Jung Kim ◽  
Yoonju Kim ◽  
...  
Keyword(s):  
Older Adults ◽  
Dna Methylation ◽  
Cognitive Function ◽  
Cognitive Aging ◽  
Community Dwelling ◽  
Test Results ◽  
Cohen’S D ◽  
Epigenetic Age ◽  
Epigenetic Age Acceleration ◽  
Community Dwelling Older Adults

Background: Epigenetic age acceleration has been studied as a promising biomarker of age-related conditions, including cognitive aging. This pilot study aims to explore potential cognitive aging-related biomarkers by investigating the relationship of epigenetic age acceleration and cognitive function and by examining the epigenetic age acceleration differences between successful cognitive aging (SCA) and normal cognitive aging (NCA) among Korean community-dwelling older adults (CDOAs). Methods: We used data and blood samples of Korean CDOAs from the Korean Frailty and Aging Cohort Study. The participants were classified into two groups, SCA (above the 50th percentile in all domains of cognitive function) and NCA. The genome-wide DNA methylation profiling array using Illumina Infinium MethylationEPIC BeadChip was used to calculate the following: the DNA methylation age, universal epigenetic age acceleration, intrinsic epigenetic age acceleration (IEAA), and extrinsic epigenetic age acceleration (EEAA). We also used Pearson correlation analysis and independent t-tests to analyze the data. Results: Universal age acceleration correlated with the Frontal Assessment Battery test results ( r = −0.42, p = 0.025); the EEAA correlated with the Word List Recognition test results ( r = −0.41, p = 0.027). There was a significant difference between SCA and NCA groups in IEAA ( p = 0.041, Cohen’s d = 0.82) and EEAA ( p = 0.042, Cohen’s d = 0.78). Conclusions: Epigenetic age acceleration can be used as a biomarker for early detection of cognitive decline in Korean community-dwelling older adults. Large longitudinal studies are warranted.

Widowhood Status and Cognitive Function in Community-Dwelling Older Adults from the Mexican Health and Aging Study (MHAS)

2021 ◽  
Author(s):  
Mariana Barragán-García ◽  
Ricardo Ramírez-Aldana ◽  
Mariana López-Ortega ◽  
Sergio Sánchez-García ◽  
Carmen García-Peña
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Community Dwelling ◽  
Aging Study ◽  
Community Dwelling Older Adults

The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study

2019 ◽  
Vol 75 ◽  
pp. 155-162 ◽  
Author(s):  
Stein-Erik Hafstad Solvang ◽  
Jan Erik Nordrehaug ◽  
Grethe S. Tell ◽  
Ottar Nygård ◽  
Adrian McCann ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Performance ◽  
Kynurenine Pathway ◽  
Community Dwelling ◽  
Health Study ◽  
Community Dwelling Older Adults

scholarly journals The Relationship between Chronotype, Physical Activity and the Estimated Risk of Dementia in Community-Dwelling Older Adults

2020 ◽  
Vol 17 (10) ◽  
pp. 3701
Author(s):  
Ngeemasara Thapa ◽  
Boram Kim ◽  
Ja-Gyeong Yang ◽  
Hye-Jin Park ◽  
Minwoo Jang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Community Dwelling ◽  
Daily Physical Activity ◽  
Estimated Risk ◽  
Community Dwelling Older Adults ◽  
The Relationship ◽  
State Examination

Our study examined the association between chronotype, daily physical activity, and the estimated risk of dementia in 170 community-dwelling older adults. Chronotype was assessed with the Horne–Östberg Morningness–Eveningness Questionnaire (MEQ). Daily physical activity (of over 3 METs) was measured with a tri-axial accelerometer. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to measure the estimated risk of dementia. The evening chronotype, low daily physical activity, and dementia were positively associated with each other. The participants with low physical activity alongside evening preference had 3.05 to 3.67 times higher estimated risk of developing dementia, and participants with low physical activity and morning preference had 1.95 to 2.26 times higher estimated risk than those with high physical activity and morning preference. Our study design does not infer causation. Nevertheless, our findings suggest that chronotype and daily physical activity are predictors of the risk of having dementia in older adults aged 70 years and above.

Yoga Education Program for Improving Memory in Older Adults: A Multicity 5-Year Follow-Up Study

2018 ◽  
Vol 39 (6) ◽  
pp. 576-587 ◽  
Author(s):  
Samta P. Pandya
Keyword(s):  
Older Adults ◽  
Education Program ◽  
Community Dwelling ◽  
Original Cohort ◽  
Cultural Variations ◽  
Highly Educated ◽  
Behavioral Memory ◽  
Community Dwelling Older Adults ◽  
State Examination

This article reports a multicity study on the effect of a yoga education program (YEP) in improving memory and cognitive functions of a nonclinical sample of community-dwelling older adults. Specifically, the intervening personal resources that bolster or hinder YEP effectiveness were examined. Of the original cohort of 918 older adults randomized into intervention and waitlist control groups, 792 remained with the study 5 years later. Results indicated that weekly YEP lessons and self-practice improved participants’ scores on the Mini-Mental State Examination (MMSE) and Rivermead Behavioral Memory Test–Third Edition (RBMT-3). Participants from Asian cities, women, Hindus and Buddhists, middle class, highly educated, retired, ever single or widowed, living alone or with children and kin, were more responsive to the YEP. Regular attendance and self-practice were strong moderators of YEP effectiveness, with self-practice having the strongest predictor effect. Some cultural variations and improvisations would lend the YEP a wider application.

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