scholarly journals Dynamic Effects in Nucleation of Receptor Clusters

Entropy ◽  
2021 ◽  
Vol 23 (10) ◽  
pp. 1245
Author(s):  
Ivan V. Prikhodko ◽  
Georgy Th. Guria

Nucleation theory has been widely applied for the interpretation of critical phenomena in nonequilibrium systems. Ligand-induced receptor clustering is a critical step of cellular activation. Receptor clusters on the cell surface are treated from the nucleation theory point of view. The authors propose that the redistribution of energy over the degrees of freedom is crucial for forming each new bond in the growing cluster. The expression for a kinetic barrier for new bond formation in a cluster was obtained. The shape of critical receptor clusters seems to be very important for the clustering on the cell surface. The von Neumann entropy of the graph of bonds is used to determine the influence of the cluster shape on the kinetic barrier. Numerical studies were carried out to assess the dependence of the barrier on the size of the cluster. The asymptotic expression, reflecting the conditions necessary for the formation of receptor clusters, was obtained. Several dynamic effects were found. A slight increase of the ligand mass has been shown to significantly accelerate the nucleation of receptor clusters. The possible meaning of the obtained results for medical applications is discussed.

2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Souvik Dutta ◽  
Thomas Faulkner

Abstract In AdS/CFT we consider a class of bulk geometric quantities inside the entanglement wedge called reflected minimal surfaces. The areas of these surfaces are dual to the entanglement entropy associated to a canonical purification (the GNS state) that we dub the reflected entropy. From the bulk point of view, we show that half the area of the reflected minimal surface gives a reinterpretation of the notion of the entanglement wedge cross-section. We prove some general properties of the reflected entropy and introduce a novel replica trick in CFTs for studying it. The duality is established using a recently introduced approach to holographic modular flow. We also consider an explicit holographic construction of the canonical purification, introduced by Engelhardt and Wall; the reflected minimal surfaces are simply RT surfaces in this new spacetime. We contrast our results with the entanglement of purification conjecture, and finally comment on the continuum limit where we find a relation to the split property: the reflected entropy computes the von Neumann entropy of a canonical splitting type-I factor introduced by Doplicher and Longo.


2018 ◽  
Vol 33 (13) ◽  
pp. 1850081 ◽  
Author(s):  
Juan Sebastián Ardenghi

The aim of this work is to introduce the entanglement entropy of real and virtual excitations of fermion and photon fields. By rewriting the generating functional of quantum electrodynamics theory as an inner product between quantum operators, it is possible to obtain quantum density operators representing the propagation of real and virtual particles. These operators are partial traces, where the degrees of freedom traced out are unobserved excitations. Then the von Neumann definition of entropy can be applied to these quantum operators and in particular, for the partial traces taken over by the internal or external degrees of freedom. A universal behavior is obtained for the entanglement entropy for different quantum fields at zeroth order in the coupling constant. In order to obtain numerical results at different orders in the perturbation expansion, the Bloch–Nordsieck model is considered, where it is shown that for some particular values of the electric charge, the von Neumann entropy increases or decreases with respect to the noninteracting case.


2012 ◽  
Vol 10 (06) ◽  
pp. 1250066 ◽  
Author(s):  
CLEMENT AMPADU

We study asymptotic entanglement properties of the Hadamard walk with phase parameters on the line using the Fourier representation. We use the von Neumann entropy of the reduced density operator to quantify entanglement between the coin and position degrees of freedom. We investigate obtaining exact expressions for the asymptotic entropy of entanglement, for different classes of initial conditions. We also determine under which conditions the asymptotic entropy of entanglement can be characterized as full, intermediate, or minimum.


2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Georgios K. Karananas ◽  
Alex Kehagias ◽  
John Taskas

Abstract We derive a novel four-dimensional black hole with planar horizon that asymptotes to the linear dilaton background. The usual growth of its entanglement entropy before Page’s time is established. After that, emergent islands modify to a large extent the entropy, which becomes finite and is saturated by its Bekenstein-Hawking value in accordance with the finiteness of the von Neumann entropy of eternal black holes. We demonstrate that viewed from the string frame, our solution is the two-dimensional Witten black hole with two additional free bosons. We generalize our findings by considering a general class of linear dilaton black hole solutions at a generic point along the σ-model renormalization group (RG) equations. For those, we observe that the entanglement entropy is “running” i.e. it is changing along the RG flow with respect to the two-dimensional worldsheet length scale. At any fixed moment before Page’s time the aforementioned entropy increases towards the infrared (IR) domain, whereas the presence of islands leads the running entropy to decrease towards the IR at later times. Finally, we present a four-dimensional charged black hole that asymptotes to the linear dilaton background as well. We compute the associated entanglement entropy for the extremal case and we find that an island is needed in order for it to follow the Page curve.


1988 ◽  
Vol 53 (4) ◽  
pp. 1177-1187
Author(s):  
W. A. MacCaull

Using formally intuitionistic logic coupled with infinitary logic and the completeness theorem for coherent logic, we establish the validity, in Grothendieck toposes, of a number of well-known, classically valid theorems about fields and ordered fields. Classically, these theorems have proofs by contradiction and most involve higher order notions. Here, the theorems are each given a first-order formulation, and this form of the theorem is then deduced using coherent or formally intuitionistic logic. This immediately implies their validity in arbitrary Grothendieck toposes. The main idea throughout is to use coherent theories and, whenever possible, find coherent formulations of formulas which then allow us to call upon the completeness theorem of coherent logic. In one place, the positive model-completeness of the relevant theory is used to find the necessary coherent formulas.The theorems here deal with polynomials or rational functions (in s indeterminates) over fields. A polynomial over a field can, of course, be represented by a finite string of field elements, and a rational function can be represented by a pair of strings of field elements. We chose the approach whereby results on polynomial rings are reduced to results about the base field, because the theory of polynomial rings in s indeterminates over fields, although coherent, is less desirable from a model-theoretic point of view. Ultimately we are interested in the models.This research was originally motivated by the works of Saracino and Weispfenning [SW], van den Dries [Dr], and Bunge [Bu], each of whom generalized some theorems from algebraic geometry or ordered fields to (commutative, von Neumann) regular rings (with unity).


Author(s):  
Mathias Fink

Time-reversal invariance can be exploited in wave physics to control wave propagation in complex media. Because time and space play a similar role in wave propagation, time-reversed waves can be obtained by manipulating spatial boundaries or by manipulating time boundaries. The two dual approaches will be discussed in this paper. The first approach uses ‘time-reversal mirrors’ with a wave manipulation along a spatial boundary sampled by a finite number of antennas. Related to this method, the role of the spatio-temporal degrees of freedom of the wavefield will be emphasized. In a second approach, waves are manipulated from a time boundary and we show that ‘instantaneous time mirrors’, mimicking the Loschmidt point of view, simultaneously acting in the entire space at once can also radiate time-reversed waves.


2013 ◽  
Vol 22 (12) ◽  
pp. 1342030 ◽  
Author(s):  
KYRIAKOS PAPADODIMAS ◽  
SUVRAT RAJU

We point out that nonperturbative effects in quantum gravity are sufficient to reconcile the process of black hole evaporation with quantum mechanics. In ordinary processes, these corrections are unimportant because they are suppressed by e-S. However, they gain relevance in information-theoretic considerations because their small size is offset by the corresponding largeness of the Hilbert space. In particular, we show how such corrections can cause the von Neumann entropy of the emitted Hawking quanta to decrease after the Page time, without modifying the thermal nature of each emitted quantum. Second, we show that exponentially suppressed commutators between operators inside and outside the black hole are sufficient to resolve paradoxes associated with the strong subadditivity of entropy without any dramatic modifications of the geometry near the horizon.


2015 ◽  
Vol 30 (16) ◽  
pp. 1530039 ◽  
Author(s):  
O. Obregón

A nonextensive statistical mechanics entropy that depends only on the probability distribution is proposed in the framework of superstatistics. It is based on a Γ(χ2) distribution that depends on β and also on pl. The corresponding modified von Neumann entropy is constructed; it is shown that it can also be obtained from a generalized Replica trick. We further demonstrate a generalized H-theorem. Considering the entropy as a function of the temperature and volume, it is possible to generalize the equation of state of an ideal gas. Moreover, following the entropic force formulation a generalized Newton's law is obtained, and following the proposal that the Einstein equations can be deduced from the Clausius law, we discuss on the structure that a generalized Einstein's theory would have. Lastly, we address the question whether the generalized entanglement entropy can play a role in the gauge/gravity duality. We pay attention to 2d CFT and their gravity duals. The correction terms to the von Neumann entropy result more relevant than the usual UV ones and also than those due to the area dependent AdS3 entropy which result comparable to the UV ones. Then the correction terms due to the new entropy would modify the Ryu–Takayanagi identification between the CFT entanglement entropy and the AdS entropy in a different manner than the UV ones or than the corrections to the AdS3 area dependent entropy.


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