scholarly journals Optic Disc Segmentation Using Attention-Based U-Net and the Improved Cross-Entropy Convolutional Neural Network

Entropy ◽  
2020 ◽  
Vol 22 (8) ◽  
pp. 844
Author(s):  
Baixin Jin ◽  
Pingping Liu ◽  
Peng Wang ◽  
Lida Shi ◽  
Jing Zhao

Medical image segmentation is an important part of medical image analysis. With the rapid development of convolutional neural networks in image processing, deep learning methods have achieved great success in the field of medical image processing. Deep learning is also used in the field of auxiliary diagnosis of glaucoma, and the effective segmentation of the optic disc area plays an important assistant role in the diagnosis of doctors in the clinical diagnosis of glaucoma. Previously, many U-Net-based optic disc segmentation methods have been proposed. However, the channel dependence of different levels of features is ignored. The performance of fundus image segmentation in small areas is not satisfactory. In this paper, we propose a new aggregation channel attention network to make full use of the influence of context information on semantic segmentation. Different from the existing attention mechanism, we exploit channel dependencies and integrate information of different scales into the attention mechanism. At the same time, we improved the basic classification framework based on cross entropy, combined the dice coefficient and cross entropy, and balanced the contribution of dice coefficients and cross entropy loss to the segmentation task, which enhanced the performance of the network in small area segmentation. The network retains more image features, restores the significant features more accurately, and further improves the segmentation performance of medical images. We apply it to the fundus optic disc segmentation task. We demonstrate the segmentation performance of the model on the Messidor dataset and the RIM-ONE dataset, and evaluate the proposed architecture. Experimental results show that our network architecture improves the prediction performance of the base architectures under different datasets while maintaining the computational efficiency. The results render that the proposed technologies improve the segmentation with 0.0469 overlapping error on Messidor.

2021 ◽  
Vol 1 (1) ◽  
pp. 14-16
Author(s):  
Debapriya Banik ◽  
Kaushiki Roy ◽  
Debotosh Bhattacharjee

This paper addresses the Instrument Segmentation Task, a subtask for the “MedAI: Transparency in Medical Image Segmentation” challenge. To accomplish the subtask, our team “Med_Seg_JU” has proposed a deep learning-based framework, namely “EM-Net: An Efficient M-Net for segmentation of surgical instruments in colonoscopy frames”. The proposed framework is inspired by the M-Net architecture. In this architecture, we have incorporated the EfficientNet B3 module with U-Net as the backbone. Our proposed method obtained a JC of 0.8205, DSC of 0.8632, PRE of 0.8464, REC of 0.9005, F1 of 0.8632, and ACC of 0.9799 as evaluated by the challenge organizers on a separate test dataset. These results justify the efficacy of our proposed method in the segmentation of the surgical instruments.


2021 ◽  
Vol 13 (3) ◽  
pp. 1224
Author(s):  
Xiangbin Liu ◽  
Liping Song ◽  
Shuai Liu ◽  
Yudong Zhang

As an emerging biomedical image processing technology, medical image segmentation has made great contributions to sustainable medical care. Now it has become an important research direction in the field of computer vision. With the rapid development of deep learning, medical image processing based on deep convolutional neural networks has become a research hotspot. This paper focuses on the research of medical image segmentation based on deep learning. First, the basic ideas and characteristics of medical image segmentation based on deep learning are introduced. By explaining its research status and summarizing the three main methods of medical image segmentation and their own limitations, the future development direction is expanded. Based on the discussion of different pathological tissues and organs, the specificity between them and their classic segmentation algorithms are summarized. Despite the great achievements of medical image segmentation in recent years, medical image segmentation based on deep learning has still encountered difficulties in research. For example, the segmentation accuracy is not high, the number of medical images in the data set is small and the resolution is low. The inaccurate segmentation results are unable to meet the actual clinical requirements. Aiming at the above problems, a comprehensive review of current medical image segmentation methods based on deep learning is provided to help researchers solve existing problems.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Qingfeng Zhang ◽  
Yun Du ◽  
Zhiqiang Wei ◽  
Hengping Liu ◽  
Xiaoxia Yang ◽  
...  

The aim was to further explore the clinical value of deep learning algorithm in the field of spinal medical image segmentation, and this study designed an improved U-shaped network (BN-U-Net) algorithm and applied it to the spinal MRI medical image segmentation of 22 research objects. The application value of this algorithm in MRI image processing was comprehensively evaluated by accuracy (Acc), sensitivity (Sen), specificity (Spe), and area under curve (AUC). The results show that the image processing time of fully convolutional network (FCN) algorithm and U-Net algorithm is greater than 6 min, while the processing time of BN-U-Net algorithm is only 5–10 s, and the processing time is significantly shortened ( P < 0.05 ). The Acc, Sen, and Spe results of BN-U-Net segmentation algorithm were 94.54 ± 3.56%, 88.76 ± 2.67%, and 86.27 ± 6.23%, respectively, which were significantly improved compared with FCN algorithm and U-Net algorithm ( P < 0.05 ). In summary, the improved U-Net network algorithm used in this study significantly improves the quality of spinal MRI images by automatic segmentation of MRI images, which is worthy of further promotion in the field of spinal medical image segmentation.


2020 ◽  
Vol 64 (2) ◽  
pp. 20508-1-20508-12 ◽  
Author(s):  
Getao Du ◽  
Xu Cao ◽  
Jimin Liang ◽  
Xueli Chen ◽  
Yonghua Zhan

Abstract Medical image analysis is performed by analyzing images obtained by medical imaging systems to solve clinical problems. The purpose is to extract effective information and improve the level of clinical diagnosis. In recent years, automatic segmentation based on deep learning (DL) methods has been widely used, where a neural network can automatically learn image features, which is in sharp contrast with the traditional manual learning method. U-net is one of the most important semantic segmentation frameworks for a convolutional neural network (CNN). It is widely used in the medical image analysis domain for lesion segmentation, anatomical segmentation, and classification. The advantage of this network framework is that it can not only accurately segment the desired feature target and effectively process and objectively evaluate medical images but also help to improve accuracy in the diagnosis by medical images. Therefore, this article presents a literature review of medical image segmentation based on U-net, focusing on the successful segmentation experience of U-net for different lesion regions in six medical imaging systems. Along with the latest advances in DL, this article introduces the method of combining the original U-net architecture with deep learning and a method for improving the U-net network.


2006 ◽  
Author(s):  
Luis Ibanez ◽  
Lydia Ng ◽  
Josh Cates ◽  
Stephen Aylward ◽  
Bill Lorensen ◽  
...  

This course introduces attendees to select open-source efforts in the field of medical image analysis. Opportunities for users and developers are presented. The course particularly focuses on the open-source Insight Toolkit (ITK) for medical image segmentation and registration. The course describes the procedure for downloading and installing the toolkit and covers the use of its data representation and filtering classes. Attendees are shown how ITK can be used in their research, rapid prototyping, and application development.LEARNING OUTCOMES After completing this course, attendees will be able to: contribute to and benefit from open-source software for medical image analysis download and install the ITK toolkit start their own software project based on ITK design and construct an image processing pipeline combine ITK filters for medical image segmentation combine ITK components for medical image registrationINTENDED AUDIENCE This course is intended for anyone involved in medical image analysis. In particular it targets graduate students, researchers and professionals in the areas of computer science and medicine. Attendees should have an intermediate level on object oriented programming with C++ and must be familiar with the basics of medical image processing and analysis.


Author(s):  
Zhenzhen Yang ◽  
Pengfei Xu ◽  
Yongpeng Yang ◽  
Bing-Kun Bao

The U-Net has become the most popular structure in medical image segmentation in recent years. Although its performance for medical image segmentation is outstanding, a large number of experiments demonstrate that the classical U-Net network architecture seems to be insufficient when the size of segmentation targets changes and the imbalance happens between target and background in different forms of segmentation. To improve the U-Net network architecture, we develop a new architecture named densely connected U-Net (DenseUNet) network in this article. The proposed DenseUNet network adopts a dense block to improve the feature extraction capability and employs a multi-feature fuse block fusing feature maps of different levels to increase the accuracy of feature extraction. In addition, in view of the advantages of the cross entropy and the dice loss functions, a new loss function for the DenseUNet network is proposed to deal with the imbalance between target and background. Finally, we test the proposed DenseUNet network and compared it with the multi-resolutional U-Net (MultiResUNet) and the classic U-Net networks on three different datasets. The experimental results show that the DenseUNet network has significantly performances compared with the MultiResUNet and the classic U-Net networks.


Symmetry ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2107
Author(s):  
Xin Wei ◽  
Huan Wan ◽  
Fanghua Ye ◽  
Weidong Min

In recent years, medical image segmentation (MIS) has made a huge breakthrough due to the success of deep learning. However, the existing MIS algorithms still suffer from two types of uncertainties: (1) the uncertainty of the plausible segmentation hypotheses and (2) the uncertainty of segmentation performance. These two types of uncertainties affect the effectiveness of the MIS algorithm and then affect the reliability of medical diagnosis. Many studies have been done on the former but ignore the latter. Therefore, we proposed the hierarchical predictable segmentation network (HPS-Net), which consists of a new network structure, a new loss function, and a cooperative training mode. According to our knowledge, HPS-Net is the first network in the MIS area that can generate both the diverse segmentation hypotheses to avoid the uncertainty of the plausible segmentation hypotheses and the measure predictions about these hypotheses to avoid the uncertainty of segmentation performance. Extensive experiments were conducted on the LIDC-IDRI dataset and the ISIC2018 dataset. The results show that HPS-Net has the highest Dice score compared with the benchmark methods, which means it has the best segmentation performance. The results also confirmed that the proposed HPS-Net can effectively predict TNR and TPR.


2021 ◽  
pp. 161-174
Author(s):  
Pashupati Bhatt ◽  
Ashok Kumar Sahoo ◽  
Saumitra Chattopadhyay ◽  
Chandradeep Bhatt

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