scholarly journals Higher-Order Cumulants Drive Neuronal Activity Patterns, Inducing UP-DOWN States in Neural Populations

Entropy ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 477 ◽  
Author(s):  
Roman Baravalle ◽  
Fernando Montani

A major challenge in neuroscience is to understand the role of the higher-order correlations structure of neuronal populations. The dichotomized Gaussian model (DG) generates spike trains by means of thresholding a multivariate Gaussian random variable. The DG inputs are Gaussian distributed, and thus have no interactions beyond the second order in their inputs; however, they can induce higher-order correlations in the outputs. We propose a combination of analytical and numerical techniques to estimate higher-order, above the second, cumulants of the firing probability distributions. Our findings show that a large amount of pairwise interactions in the inputs can induce the system into two possible regimes, one with low activity (“DOWN state”) and another one with high activity (“UP state”), and the appearance of these states is due to a combination between the third- and fourth-order cumulant. This could be part of a mechanism that would help the neural code to upgrade specific information about the stimuli, motivating us to examine the behavior of the critical fluctuations through the Binder cumulant close to the critical point. We show, using the Binder cumulant, that higher-order correlations in the outputs generate a critical neural system that portrays a second-order phase transition.

Author(s):  
G. Jacobs ◽  
F. Theunissen

In order to understand how the algorithms underlying neural computation are implemented within any neural system, it is necessary to understand details of the anatomy, physiology and global organization of the neurons from which the system is constructed. Information is represented in neural systems by patterns of activity that vary in both their spatial extent and in the time domain. One of the great challenges to microscopists is to devise methods for imaging these patterns of activity and to correlate them with the underlying neuroanatomy and physiology. We have addressed this problem by using a combination of three dimensional reconstruction techniques, quantitative analysis and computer visualization techniques to build a probabilistic atlas of a neural map in an insect sensory system. The principal goal of this study was to derive a quantitative representation of the map, based on a uniform sample of afferents that was of sufficient size to allow statistically meaningful analyses of the relationships between structure and function.


2020 ◽  
Vol 26 ◽  
pp. 37 ◽  
Author(s):  
Elimhan N. Mahmudov

The present paper studies the Mayer problem with higher order evolution differential inclusions and functional constraints of optimal control theory (PFC); to this end first we use an interesting auxiliary problem with second order discrete-time and discrete approximate inclusions (PFD). Are proved necessary and sufficient conditions incorporating the Euler–Lagrange inclusion, the Hamiltonian inclusion, the transversality and complementary slackness conditions. The basic concept of obtaining optimal conditions is locally adjoint mappings and equivalence results. Then combining these results and passing to the limit in the discrete approximations we establish new sufficient optimality conditions for second order continuous-time evolution inclusions. This approach and results make a bridge between optimal control problem with higher order differential inclusion (PFC) and constrained mathematical programming problems in finite-dimensional spaces. Formulation of the transversality and complementary slackness conditions for second order differential inclusions play a substantial role in the next investigations without which it is hardly ever possible to get any optimality conditions; consequently, these results are generalized to the problem with an arbitrary higher order differential inclusion. Furthermore, application of these results is demonstrated by solving some semilinear problem with second and third order differential inclusions.


Symmetry ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1016
Author(s):  
Camelia Liliana Moldovan ◽  
Radu Păltănea

The paper presents a multidimensional generalization of the Schoenberg operators of higher order. The new operators are powerful tools that can be used for approximation processes in many fields of applied sciences. The construction of these operators uses a symmetry regarding the domain of definition. The degree of approximation by sequences of such operators is given in terms of the first and the second order moduli of continuity. Extending certain results obtained by Marsden in the one-dimensional case, the property of preservation of monotonicity and convexity is proved.


2021 ◽  
Vol 502 (3) ◽  
pp. 3976-3992
Author(s):  
Mónica Hernández-Sánchez ◽  
Francisco-Shu Kitaura ◽  
Metin Ata ◽  
Claudio Dalla Vecchia

ABSTRACT We investigate higher order symplectic integration strategies within Bayesian cosmic density field reconstruction methods. In particular, we study the fourth-order discretization of Hamiltonian equations of motion (EoM). This is achieved by recursively applying the basic second-order leap-frog scheme (considering the single evaluation of the EoM) in a combination of even numbers of forward time integration steps with a single intermediate backward step. This largely reduces the number of evaluations and random gradient computations, as required in the usual second-order case for high-dimensional cases. We restrict this study to the lognormal-Poisson model, applied to a full volume halo catalogue in real space on a cubical mesh of 1250 h−1 Mpc side and 2563 cells. Hence, we neglect selection effects, redshift space distortions, and displacements. We note that those observational and cosmic evolution effects can be accounted for in subsequent Gibbs-sampling steps within the COSMIC BIRTH algorithm. We find that going from the usual second to fourth order in the leap-frog scheme shortens the burn-in phase by a factor of at least ∼30. This implies that 75–90 independent samples are obtained while the fastest second-order method converges. After convergence, the correlation lengths indicate an improvement factor of about 3.0 fewer gradient computations for meshes of 2563 cells. In the considered cosmological scenario, the traditional leap-frog scheme turns out to outperform higher order integration schemes only when considering lower dimensional problems, e.g. meshes with 643 cells. This gain in computational efficiency can help to go towards a full Bayesian analysis of the cosmological large-scale structure for upcoming galaxy surveys.


2021 ◽  
Vol 22 (2) ◽  
pp. 1-37
Author(s):  
Christopher H. Broadbent ◽  
Arnaud Carayol ◽  
C.-H. Luke Ong ◽  
Olivier Serre

This article studies the logical properties of a very general class of infinite ranked trees, namely, those generated by higher-order recursion schemes. We consider, for both monadic second-order logic and modal -calculus, three main problems: model-checking, logical reflection (a.k.a. global model-checking, that asks for a finite description of the set of elements for which a formula holds), and selection (that asks, if exists, for some finite description of a set of elements for which an MSO formula with a second-order free variable holds). For each of these problems, we provide an effective solution. This is obtained, thanks to a known connection between higher-order recursion schemes and collapsible pushdown automata and on previous work regarding parity games played on transition graphs of collapsible pushdown automata.


Author(s):  
Jia-Ding Cao ◽  
Heinz H. Gonska

AbstractDeVore-Gopengauz-type operators have attracted some interest over the recent years. Here we investigate their relationship to shape preservation. We construct certain positive convolution-type operators Hn, s, j which leave the cones of j-convex functions invariant and give Timan-type inequalities for these. We also consider Boolean sum modifications of the operators Hn, s, j show that they basically have the same shape preservation behavior while interpolating at the endpoints of [−1, 1], and also satisfy Telyakovskiῐ- and DeVore-Gopengauz-type inequalities involving the first and second order moduli of continuity, respectively. Our results thus generalize related results by Lorentz and Zeller, Shvedov, Beatson, DeVore, Yu and Leviatan.


2011 ◽  
Vol 18 (01) ◽  
pp. 71-85
Author(s):  
Fabrizio Cacciafesta

We provide a simple way to visualize the variance and the mean absolute error of a random variable with finite mean. Some application to options theory and to second order stochastic dominance is given: we show, among other, that the "call-put parity" may be seen as a Taylor formula.


2004 ◽  
Vol 14 (08) ◽  
pp. 2979-2990 ◽  
Author(s):  
FANJI GU ◽  
ENHUA SHEN ◽  
XIN MENG ◽  
YANG CAO ◽  
ZHIJIE CAI

A concept of higher order complexity is proposed in this letter. If a randomness-finding complexity [Rapp & Schmah, 2000] is taken as the complexity measure, the first-order complexity is suggested to be a measure of randomness of the original time series, while the second-order complexity is a measure of its degree of nonstationarity. A different order is associated with each different aspect of complexity. Using logistic mapping repeatedly, some quasi-stationary time series were constructed, the nonstationarity degree of which could be expected theoretically. The estimation of the second-order complexity of these time series shows that the second-order complexities do reflect the degree of nonstationarity and thus can be considered as its indicator. It is also shown that the second-order complexities of the EEG signals from subjects doing mental arithmetic are significantly higher than those from subjects in deep sleep or resting with eyes closed.


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