scholarly journals Is the Fatty Acids Profile in Blood a Good Predictor of Liver Changes? Correlation of Fatty Acids Profile with Fatty Acids Content in the Liver

Diagnostics ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 197 ◽  
Author(s):  
Dominika Maciejewska ◽  
Joanna Palma ◽  
Karolina Dec ◽  
Karolina Skonieczna-Żydecka ◽  
Izabela Gutowska ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Vaccenic Acid ◽  
Dietary Exposure ◽  
Docosapentaenoic Acid ◽  
Control Group ◽  
Study Group ◽  
Sprague Dawley ◽  
Laboratory Rats ◽  
Fatty Acids Profile ◽  
Liver Changes

Background: Existing data show a correlation between the profile of fatty acids, liver, and blood. Therefore, the aim of our study was to investigate the correlation between the fatty acids profile in blood pallets and the liver. Methods: The experiment was performed on 60 eight-week-old male Sprague-Dawley rats. The study group (n = 30, 5 groups, 6 rats each) received a cholesterol diet; the control group (n = 30, 5 groups, 6 rats each) received standard food for laboratory rats. The rats from both the study and control groups were sacrificed after 2, 4, 8, 12, and 16 weeks of dietary exposure. The fatty acids profile was measured using gas chromatography (GC). Results: In both the control and study group, the highest correlations were observed in palmitoleic acid (RHO = 0.68), heptadecanoic acid (RHO = 0.65), vaccenic acid (RHO = 0.72), eicosapentaenoic acid (RHO = 0.68), docosapentaenoic acid (RHO = 0.77), and docosahexaenoic (RHO = 0.77). Among liver indexes, the highest correlations were desaturase-18 (0.61). Conclusions: Fatty acids profile is a sensitive marker of the development of potentially pathological changes in the liver. The potential markers of fatty liver are: oleic acid, vaccenic acid, EPA, DHA, docosapentaenoic acid, and desaturase index (SCD-18 index).

scholarly journals Evaluation of the eating habits of breast cancer patients

2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Tuba Kayan Tapan ◽  
Zeynep Erdogan Iyigun ◽  
Serkan Ilgun ◽  
Vahit Ozmen
Keyword(s):  
Breast Cancer ◽  
Fatty Acids ◽  
Cancer Patients ◽  
Eating Habits ◽  
Saturated Fatty Acids ◽  
Water Soluble ◽  
Control Group ◽  
Study Group ◽  
Vitamin B2 ◽  
Breast Cancer Patients

Objective: To determine the relationship between the dietary characteristics of breast cancer patients. Methods: Patients with breast cancer whose treatments have finished and are in remission formed the study group and healthy people formed the control group. Demographic, anthropometric characteristics, food consumption frequency form and exercise status were recorded with all groups. Data analysis was done by SPSS 22. Results: In the study group, mean carbohydrate percentage was lower, while fat, fat percentage, monosaccharide, glucose, fructose, omega3(n3), saturated fatty acids(SFA), monounsaturated fatty acids (MUFA), vitamin A, C, E, B6, biotin and copper values were significantly higher (p<0.05). Recurrence was observed in seven patients (7.1%) during the follow-up period, hormone receptor levels (ER) and vitamin B2 intake (accuracy 93.9%) were inversely related to the recurrence of the disease (p=0.02). Conclusions: While the percentage of carbohydrate taken was lower in study group; total fat, n3, SFA, MUFA, monosaccharide, glucose, fructose, water-soluble fiber, B6, biotin and copper values were higher. Further studies are needed for vitamin B2 deficiency in patients with recurrence. doi: https://doi.org/10.12669/pjms.36.7.2368 How to cite this:Tapan TK, Iyigun ZE, Ilgun S, Ozmen V. Evaluation of the eating habits of breast cancer patients. Pak J Med Sci. 2020;36(7):---------. doi: https://doi.org/10.12669/pjms.36.7.2368 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals The Effect of Feeding Chicken and Geese Broilers with Different Cereals on the Fatty Acids Profile in Meat

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2879
Author(s):  
Piotr Janiszewski ◽  
Dariusz Lisiak ◽  
Karol Borzuta ◽  
Eugenia Grześkowiak ◽  
Tomasz Schwarz ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Meat Quality ◽  
Rapeseed Oil ◽  
Control Group ◽  
Final Body Weight ◽  
Pufa Ratio ◽  
Fatty Acids Profile ◽  
Hybrid Rye ◽  
Effect Of Feeding

The research was conducted on the effect of bird broilers fed with different hybrid rye doses on the fatty acids profile in muscle. The first experiment was performed on 3 geese broilers groups fed with hybrid rye, oats or hybrid rye and oats mix in proportion 1:1. No effect of the hybrid rye feeding of geese on the SFA level in meat was observed, but the MUFA level was significantly higher and PUFA level and n-6/n-3 PUFA ratio were significantly lower than in geese fed with oats. The second experiment was performed on 3 chicken broiler groups fed with mix of corn, wheat, soybean meal and rapeseed oil (control group), and fed with an addition of 10% or 20% hybrid rye in diet (experimental groups). No effect of hybrid rye feeding of chicken broilers on the meat quality and SFA level was observed. However, the MUFA level was higher and the PUFA level and n-6/n-3 PUFA ratio were lower in meat of chicken broilers fed with hybrid rye. In conclusion hybrid rye is a healthy ingredient in the diet of studied birds and may be used up to 20% in chicken broilers and 50% in the diets of geese. A 100% hybrid rye in geese diet caused lower final body weight.

scholarly journals Studying the effects of fish oil infusion to prevent atrial fibrillation after cardiac surgery: data from implantable continuous cardiac monitor

2015 ◽  
Vol 18 (3) ◽  
pp. 12
Author(s):  
S. M. Yefremov ◽  
Ye. A. Pokushalov ◽  
A. B. Romanov ◽  
A. M. Chernyavskiy ◽  
A. N. Shilova ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Postoperative Atrial Fibrillation ◽  
Controlled Study ◽  
Control Group ◽  
Study Group ◽  
Omega 3 ◽  
Cardiac Monitor

The study was aimed at testing the hypothesis that perioperative infusion of omega-3 polyunsaturated fatty acids would reduce the incidence of postoperative atrial fibrillation in CAD patients operated under CPB. The authors carried out a prospective, randomised, double-blind, placebo-controlled study. 39 CAD patients who had undergone surgery under cardiopulmonary bypass were randomized into 2 groups. 18 patients were infused with omega-3 polyunsaturated fatty acids (Omegaven, Fresenius Kabi, Germany) starting with 200 mg/kg/day before anaesthesia induction for 24 hours followed by 100 mg/kg/day from second to seventh day postoperatively. 21 patients received an equivalent dose of placebo (Intralipid, Fresenius Kabi, Germany). The primary endpoint was freedom from atrial fibrillation at 2-year follow-up. A Reveal cardiac monitor was implanted subcutaneously in all patients. Data from cardiac monitor was collected on the 10th day and at 3, 6, 12 and 24 months postoperatively. Postoperative atrial fibrillation developed in 4 (19%) patients in the control group and in 5 (27.8%) patients in the study group at 10-day follow-up (p = 0.88). At 2-year follow-up, 5 (27.8%) patients in the control group and 6 (35.3%) patients in the study group had atrial fibrillation (p = 0.9). The results of our research do not confirm the efficiency of perioperative infusion of omega-3 polyun-saturated fatty acids to prevent the occurrence of atrial fibrillation.

scholarly journals STUDY OF THE LEVEL OF FATTY ACIDS IN ERYTHROCYTE MEMBRANES AND SERUM OF PATIENTS WITH COLORECTAL CANCER IN NOVOSIBIRSK

2018 ◽  
Vol 5 (2) ◽  
pp. 50-61 ◽  
Author(s):  
M. V. Kruchinina ◽  
V. N. Kruchinin ◽  
Ya. I. Prudnikova ◽  
A. A. Gromov ◽  
M. V. Shashkov ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acids ◽  
Monounsaturated Fatty Acids ◽  
Erythrocyte Membranes ◽  
Control Group ◽  
Study Group ◽  
Omega 3 ◽  
Healthy Individuals ◽  
Internal Organs ◽  
Omega 6

The objectiveis to measure the level of fatty acids in erythrocyte membranes and serum of patients with colorectal cancer.Materials and methods.The study group included 100 patients with diagnosed colorectal cancer (57 men and 43 women). The control group included 24 reasonably healthy people (14 men and 10 women) matched for age and sex, without malignant cancers or manifested pathology of the internal organs.Results.Decreased levels of saturated, monounsaturated fatty acids and increased levels of polyunsaturated fatty acids (PUFAs) in erythrocyte membranes and serum (p <0.0001–0.05) were observed. The levels of omega-3 PUFAs in colorectal cancer exceeded the levels in healthy individuals both in erythrocyte membranes and in serum; for omega-6 PUFAs only a trend was observed. At the same time, the ratio of omega-6/omega-3 PUFAs in colorectal cancer was lower than in control (p <0.0001–0.002). The state of erythrocyte membranes more significantly and for more parameters characterized differences between the groups than serum. The most discriminating parameters between patients with colorectal cancer and healthy individuals both in erythrocyte membranes and serum were the levels of C20:2;11,14 (eicosadienoic), C20:3;8,11,14 (dihomo-γ-linolenic), C20:4;5,8,11,14 (eicosatetraenoic, arachidonic), C22:5;7,10,13,16,19 (docosapentaenoic), and C22:6;4,7,10,13,16,19 (docosahexaenoic) PUFAs.

scholarly journals Camelina Meal and Chromium Picolinate Effects on Broiler Thigh Meat Nutritional Properties

2021 ◽  
Vol 24 (2) ◽  
pp. 96-104
Author(s):  
Arabela Elena Untea ◽  
Tatiana Dumitra Panaite ◽  
Alexandra Oancea ◽  
Raluca Paula Turcu ◽  
Mihaela Saracila
Keyword(s):  
Fatty Acids ◽  
Broiler Chicken ◽  
Chromium Picolinate ◽  
Control Group ◽  
Omega 3 ◽  
Nutritional Properties ◽  
Fatty Acids Profile ◽  
Camelina Meal ◽  
Inclusion Rate ◽  
Dietary Treatments

Abstract The aim of this study was to evaluate the combined effects of trivalent chromium and camelina meal on proximate composition, mineral content and fatty acids profile of broiler chicken thigh meat. An experiment with 2 x 3 factorial arrangement was performed on 240 Ross 308 broiler chicken aged 14 days. Six dietary treatments were elaborated as follows: 0 and 3% inclusion rate of Camelina meal and 0, 200 and 400 μg/kg chromium picolinate (CrPic). Supplementation of broiler diets with 3% Camelina meal led to significantly (P<0.05) increased crude fat concentrations in thigh samples compared to control group or with single chromium supplemented groups. In thigh samples, Zn and Fe concentrations increased under CrPic influence and fatty acids profile was influenced by Camelina meal presence in the diets. In Camelina meal supplemented groups, were registered significantly increased omega 3 fatty acids concentrations compared to control group or single chromium supplemented groups. The results of the present study found that Camelina meal and chromium picolinate supplements in broilers diets improved the nutritional properties of thigh meat, especially essential minerals content and fatty acids profile.

scholarly journals Effect of dietary phyto-humic preparations on lipids indices of commercial laying hen eggs

2019 ◽  
Vol 75 (03) ◽  
pp. 6197-2019 ◽  
Author(s):  
FABIOLA BUBEL ◽  
ZBIGNIEW DOBRZAŃSKI ◽  
EUGENIUSZ R. GRELA ◽  
ŁUKASZ BOBAK ◽  
MACIEJ OZIEMBŁOWSKI
Keyword(s):  
Fatty Acids ◽  
Total Cholesterol ◽  
Cholesterol Content ◽  
Atherogenic Index ◽  
Control Group ◽  
Fatty Acids Profile ◽  
Group A ◽  
Dietary Value ◽  
Thrombogenic Index ◽  
Group B

The aim of the study was to determine the effect of three different phyto-humic feed preparations on the basic qualitative characteristics of eggs, i.e. total cholesterol content and fatty acid profile of the yolk. The study was carried out on 80 Lohmann Brown (LB) laying hens in an experimental facility with a floor maintenance system on a straw bedding (5 layers/m2). A control group (K) and three experimental ones (A, B, C), with 20 birds in each (in separate pens), were created. The birds were placed in the 16th week of life, while the experimental preparations were introduced in the 22nd week of life and were administered for 43 weeks (constant 3% addition to the feed mixture).The following preparations were applied: humic-peat (H-t) in group A, humic-herbal (H-z) in group B, and humic-lucerne (H-1) in group C. The eggs for the study were collected three times, 30 eggs from each group in the following periods: 1st series – 31st week of life (peak of laying period); 2nd series – 54th week of life (later phase of laying period) and 3rd series – 65th week of life (final phase of laying period). Six samples (mean of 5 well-mixed yolks) from each group in three laying periods (360 eggs were used in total) were prepared for laboratory analyzes (lipids examination). Laboratory analyzes were performed using a chromatograph – Finnigan Focus PolarisQ manufactured by Thermo Electron with capillary columns: HP-88 by Agilent J&W (fatty acids) and Rtx-1MS by Restek (cholesterol). The applied phytohumic preparations – but only those with a share of dried lucerne or herbs – significantly (p ≤ 0.05) reduced total cholesterol content, especially in group C (10.88 mg/g yolk) compared to group K (11.94 mg/g yolk). All preparations positively influenced the fatty acids profile of yolk; there was a significant (p ≤ 0.05) increase in the concentration of n-3 PUFAs (max 2.84% in the group B), the n-6/n-3 ratio decreased significantly (most beneficial 8.33 in group B), and lipids quality improved: atherogenic index (AI) decreased significantly (p ≤ 0.05) in group A (0.32) and thrombogenic index (TI) was a significantly (p ≤ 0.05) lower in all experimental groups (0.83 – 0.84) compared to group K (0.36 and 0.87 respectively). Dietary phyto-humic preparations increased the nutritional and dietary value of hen eggs.

Efficacy of maslinic acid and fenbendazole on muscle larvae of Trichinella zimbabwensis in laboratory rats

2015 ◽  
Vol 90 (1) ◽  
pp. 86-90 ◽  
Author(s):  
S. Mukaratirwa ◽  
L. Gcanga ◽  
J. Kamau
Keyword(s):  
Untreated Control ◽  
Nematode Species ◽  
Control Group ◽  
Average Weight ◽  
Sprague Dawley ◽  
Untreated Control Group ◽  
Maslinic Acid ◽  
Laboratory Rats ◽  
Larval Stages ◽  
Muscle Larvae

AbstractTrichinellosis is a zoonotic disease caused by nematode species of the genus Trichinella. Anthelmintics targeting the intestinal adults and muscle-dwelling larvae of Trichinella spp. have been tested, with limited success. This study was aimed at determining the efficacy of maslinic acid and fenbendazole on muscle larvae of Trichinella zimbabwensis in laboratory rats. Forty-two Sprague–Dawley rats, with an average weight of 270 g and 180 g for males and females respectively, were infected with T. zimbabwensis larvae. Infected rats were randomly assigned to three groups which were subjected to single treatments with each of maslinic acid, fenbendazole and a combination of both on day 25 post-infection (pi), and three groups which were subjected to double treatments with each of these drugs and a combination on days 25 and 32 pi. The untreated control group received a placebo. In single-treatment groups, the efficacy of each treatment, measured by rate of reduction in muscle larvae, was significant (P< 0.001) for both drugs compared to the untreated control group. There was no apparent synergistic effect on the combination of the two drugs in reducing the muscle larval burden, either in single or double treatments. In all the treatment regimens, the reductions were significant (P< 0.001) when compared to the untreated control and not significant when the single treatments were compared with the double treatments (P>0.05). We conclude that the efficacy of maslinic acid against larval stages of T. zimbabwensis in rats was comparable to that of fenbendazole, with no side-effects observed, making maslinic acid a promising anthelmintic against larval stages of Trichinella species.

scholarly journals Effects of three different diets on the fatty acid profile and sensory properties of fresh Pecorino cheese “Primo Sale”

2020 ◽  
Vol 33 (12) ◽  
pp. 1991-1998 ◽  
Author(s):  
Isa Fusaro ◽  
Melania Giammarco ◽  
Michael Odintsov Vaintrub ◽  
Matteo Chincarini ◽  
Anna Chiara Manetta ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Feeding Strategy ◽  
Vaccenic Acid ◽  
Control Diet ◽  
Saturated Fatty Acids ◽  
Sensory Properties ◽  
Control Group ◽  
Acid Ratio ◽  
Fresh Cheese

Objective: This study aimed to evaluate and compare the effects of three different diets on the fatty acids (FA) profile and sensory properties of a characteristic Italian fresh cheese: Pecorino "Primo Sale” (PS).Methods: Fifty-four sheep were divided into three feeding groups: total mixed ration (TMR) enriched with extruded linseed (TL), control diet with TMR without any integration (TC), and pasture (P). During cheese production, six cheeses per experimental group were produced each week, stored for 10 days at 4°C, and then analyzed for chemical composition, FA profile, and sensory properties.Results: Saturated fatty acids (SFA) were significantly higher in PS from group TC (82.11%) than in cheese from other two groups (P 75.48% and TL 66.83%). TL and P groups presented higher values of polyunsaturated fatty acids, 4.35 and 3.65%, respectively, than that of TC group (2.31%). The lowest SFA/unsaturated fatty acid ratio was found in TL and P groups, while the highest was found in the TC group. Vaccenic acid and conjugated linoleic acid (CLA) were higher in group P (p<0.05) than in groups L and TC. Sensory properties of cheese from group P received the highest scores for odor intensity and friability, while control group had a greater chewing consistency. Overall, all cheeses received good scores for acceptability.Conclusion: In conclusion, this study showed how the integration of extruded linseed improved the FA profile of fresh pecorino cheese PS preserving its sensory properties. Levels of CLA in the PS group achieved using this approach was not higher than that in a grazing diet. Cheeses from groups P and L contained a higher value of FA, with nutritional implications for humans, when compared with un-supplemented diet. Linseed may be a good feeding strategy when pasture is not available.

scholarly journals A review of the effects of different feeding regimes of cows on milk fatty acids profile and antioxidant capacity

2021 ◽  
Vol 78 (2) ◽  
pp. 6
Author(s):  
Anita ȘANTA ◽  
Daniel MIERLIȚĂ ◽  
Claudia SOCOL ◽  
Stelian DĂRĂBAN
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Vaccenic Acid ◽  
Lower Content ◽  
Milk Fatty Acids ◽  
Fatty Acids Profile ◽  
Green Fodder ◽  
Feeding Regimes ◽  
Quality Of Milk

This bibliography review analyzes the effects of different feeding regimes of cows the nutritional and sanogenic quality of milk, with a particular emphasis on milk content in functional fatty acids and non-enzymatic lipophilic antioxidants. Thus, using suitable feeding regimes of cows, fatty acid (FA) profile of milk fats can be improved by increasing the concentration in functional FA (C18:1 trans-11, vaccenic acid; C18:3 n-3, acid linolenic and C18:2 cis-9 trans-11, isomer of conjugated linoleic acid), considered as beneficial for consumer’s health. These suitable feeding regimes of cows aim using green fodder (pastures), preserving the fodder by drying or silage, supplementing the food with fats rich FA polyunsaturated (PUFA) and ensuring an optimal ratio between volume and ration concentrates. Milk yielded from grazing cows shows a considerably higher concentration of functional FA and lipophilic antioxidants (tocopherols, retinol and carotenes) and a lower content of saturated FA compared to that yielded from cows fed in shelter with TMR (total mixed ration). Also, hay-based feed rations, mainly those containing small amounts of concentrates or those supplemented with vegetable fats, ensure a milk yield with a fatty acid profile more favorable for human health and a better oxidative stability of compared to those with feed-based rations on silage or those high in concentrates.

Fatty acid profile, antioxidative status and dietary value of the breast muscle of broiler chickens receiving glycine-Zn chelates

2020 ◽  
Vol 60 (8) ◽  
pp. 1095
Author(s):  
Anna Winiarska-Mieczan ◽  
Małgorzata Kwiecień ◽  
Katarzyna Kwiatkowska ◽  
Ewa Baranowska-Wójcik ◽  
Dominik Szwajgier ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Broiler Chickens ◽  
The Body ◽  
Breast Muscle ◽  
Atherogenic Index ◽  
Control Group ◽  
Breast Meat ◽  
Antioxidative Status ◽  
Fatty Acids Profile ◽  
Zn Chelates

In the present study we aimed to examine the effect of glycine-Zn chelates (ZnGly) used in amounts corresponding to 0, 100, 50 or 25% of the requirement of this element on the fatty acids profile, antioxidative status, and dietetic value (atherogenic index (AI), thrombogenic index (TI), hypocholesterolemic/hypercholesterolemic ratio (h/H)) of breast muscles in broiler chickens. Two hundred 1-day-old Ross 308 male chicks were split into four equipotent experimental groups (assigned to 20 cages, 10 chicks in each, replicated five times): control, ZnGly-100, ZnGly-50 and ZnGly-25. The broilers received feed and water ad libitum. The experiment lasted 42 days. Significant differences in the content of respective fatty acids in the meat of chickens receiving ZnGly were observed in comparison to the control group; but they were not directional changes. A positive effect (P &lt; 0.05) of Zn-Gly on certain indices of meat determined by the oxidoreductive status of the body or regulating such status was noted: superoxide dismutase, catalase and malondialdehyde. A significant effect of ZnGly on the dietetic value of broiler chickens’ breast meat was noted: the highest (P &lt; 0.05) AI value was found in the ZnGly-50 and ZnGly-25 groups, and TI value in the ZnGly-25 group. The h/H relationship can be presented as ZnGly-25 &lt; ZnGly-50 &lt; ZnGly-100 &lt; control group. To improve the dietetic value and to increase the oxidative stability of breast muscle meat, broiler chickens must receive ZnGly in an amount corresponding to more than 25% of the requirement of this element.

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