scholarly journals COVID-19 in Patients with Active Tuberculosis

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1768
Author(s):  
Monika Kozińska ◽  
Ewa Augustynowicz-Kopeć

Data on the coincidence of tuberculosis (TB) and COVID-19 are limited, and previous observations are based on the results of just a few studies, which has led to polarized views on the course of infection with SARS-CoV-2 in patients with active TB. We present the first two cases of TB and COVID-19 coinfection in the population of patients in Poland, diagnosed shortly after the outbreak of the global pandemic. In the first patient, TB was very advanced at the time of infection with SARS-CoV-2. From the third day of hospitalisation, respiratory failure was increasing, with no improvement after the use of high-flow oxygen therapy and mechanical ventilation. On the seventh day of hospitalization, the patient died. In the second presented case, therapeutic success was achieved despite the coincidence of COVID-19, infection with HIV, and extrapulmonary and pulmonary TB. The patient had symptoms of renal failure and the SARS-CoV-2 infection was mild and asymptomatic. Because both patients were in the care of a homeless shelter, a molecular epidemiological investigation was carried out. Different DNA profiles of Mycobacterium tuberculosis complex isolates detected in clinical materials from patients ruled out the transmission of tuberculosis. Based on our analysis, it is impossible to clearly define the influence of active TB on the course of SARS-CoV-2 infection. We can only suggest that coinfection is particularly dangerous for socially disadvantaged people, the elderly, and people with other comorbidities. In the coming years, a negative impact of the current pandemic on control programmes will be observed for many infectious diseases, including TB.

2020 ◽  
Vol 9 (12) ◽  
pp. 4124
Author(s):  
Barbara Molina-Moya ◽  
Nelly Ciobanu ◽  
Marta Hernandez ◽  
Cristina Prat-Aymerich ◽  
Valeriu Crudu ◽  
...  

Tuberculosis (TB) diagnosis is increasingly based on the detection of Mycobacterium tuberculosis complex (MTBC) DNA in sputum using molecular diagnostic tests as the first test for diagnosis. However, sputum can be difficult to obtain in children, patients without productive cough, and the elderly and approaches testing non-sputum samples are needed. We evaluated whether TB can be detected from the oral mucosa of patients with TB. Adults with presumptive TB were examined using culture, Xpert MTB/RIF, smear microscopy and X-Rays. Oral mucosa swabs collected on PrimeStore-MTM, stored at room temperature if tested within 30 days or at −20 °C if examined at a later time. RT-PCR was performed to detect M. tuberculosis DNA. Eighty patients had bacteriologically-confirmed TB, 34 had bacteriologically-negative TB (negative tests but abnormal X-rays) and 152 were considered not to have TB (not TB). Oral swabs RT-PCR were positive in 29/80 (36.3%) bacteriologically-confirmed, 9/34 (26.5%) bacteriologically-negative and 29/152 (19.1%) not TB. The yield varied among samples stored for less and more than 30 days (p = 0.013) from 61% (11/18) and 29% (18/62) among bacteriologically confirmed, and 30.8% (4/13) and 23.8% (5/21) among bacteriologically-negative participants. Among not TB patients, the specificity was 80.9% (123/152), being 78.3% (18/23) among samples stored less than 30 days and 81.4% (105/129) among samples stored for more than 30 days (p = 0.46). The detection of M. tuberculosis in oral mucosa samples is feasible, but storage conditions may affect the yield.


Work ◽  
2021 ◽  
pp. 1-11
Author(s):  
Yan Xu ◽  
Wantian Cui

BACKGROUND: China’s atmospheric PM2.5 pollution is serious, and PM2.5 exerts a negative impact on the human respiratory system, cardiovascular, and mental health, and even more serious health risk for the elderly with weak immunity. OBJECTIVE: This work aims to analyse the impacts of PM2.5 microenvironment exposure on the health of the elderly and provide corresponding countermeasures. METHODS: The survey subjects are 118 retired elderly people in the community. PM2.5 exposure concentrations are monitored in summer (June 10 ∼ July 10, 2019) and winter (November 25 ∼ December 25, 2019). RESULTS: The exposure concentration in winter is higher than that in summer, with statistical difference (P <  0.05). Under the impact of PM2.5 microenvironment exposure, smoking in the elderly can increase the concentration of PM2.5, and long-term exposure to PM2.5 in the elderly can cause mental health problems. CONCLUSION: Long-term exposure of the elderly to the PM2.5 microenvironment leads to physical diseases and even psychological problems, which requires attention.


2020 ◽  
pp. 105477382098230
Author(s):  
Frank Kyei-Arthur ◽  
Samuel Nii Ardey Codjoe

This study is part of a broader phenomenological study on the experiences of family caregivers and their care recipients. There is a general paucity of research on the experiences of primary and secondary caregivers, and the negative impact of elderly care on caregivers in the urban poor settings in Ghana. This study explored primary and secondary caregivers’ challenges and coping strategies in the urban poor context in Accra, Ghana. This study was conducted in Ga Mashie. Thirty-one caregivers were interviewed. A phenomenological analysis was conducted using NVivo 10. Primary and secondary caregivers experienced economic, physical, social, and psychological burdens. Also, caregivers used spirituality and perseverance to cope with their challenges. The findings demonstrate that caregivers’ challenges varied by type of caregiver. Researchers and policymakers should consider the type of caregiver when designing interventions to mitigate the negative impacts of family caregiving on caregivers.


2021 ◽  
pp. 270-278
Author(s):  
Tatyana Borisovna Berestok

This article deals with the issue of self-preservation of elderly people when learning to work on a computer from the point of view of information and psychological security. The necessity of solving new socio-psychological problems is indicated: to develop the ability to give a correct assessment of a specific information threat, to prevent the negative impact of the information environment, to resist negative factors, and to contribute to improving the quality of life. The purpose of counseling elderly people is to develop their ability to understand the problem of the negative impact of the information environment on psychological and physiological health, to be able to apply methods to ensure information and psychological security. Consulting and educational work with the elderly and employees of social institutions engaged in professional activities directly related to the above category should be aimed at preventing cases of fraudulent activities. Consulting work with them should not only meet the general principles of building psychological contact, but also cause an understanding of the importance of compliance with security in the digital sphere. Elderly people develop the ability to assess correctly a specific information threat and prevent the negative impact of the information environment by providing adequate resistance to negative factors and contributing to improving their quality of life. It is increasingly difficult for older people to navigate threats, unmotivated anxiety increases, depressiveness appears and becomes fixed, and asocial personality traits are formed. At the present time, it is necessary to consider the formation of information and computer literacy as a mechanism to counteract the negative impact of the information environment and a necessary condition for developing an effective strategy for the social adaptation of elderly people.


2021 ◽  
Vol 12 (4) ◽  
pp. 69-73
Author(s):  
D. Bachyncova Giertliova

The paper discusses and summarizes the knowledge in the field of education of socially disadvantaged children with an em- phasis on the Roma ethnic group in Slovakia. It focuses on the issue of pre-primary education of these children and points to the specifics that have a negative impact on the adaptation to the school educational process. The paper addresses the risk aspects of poverty, social exclusion, child development and the need for early intervention for families with children. Further- more, in the article we focus on the support of children at the community level and on possible forms of aid that can help to achieve a more favorable development of the overall Roma family within specific projects. We also deal with early care, which is very important for the bio-psycho-social development of children and youth.


2021 ◽  
Vol 13 (20) ◽  
pp. 11222
Author(s):  
Daniel Salcedo-López ◽  
Mercedes Cuevas-López

The Erasmus+ program (2014–2020) is one of the main initiatives developed by the European Commission in the field of education and is the final joint evolution of other minor and prior actions that provide schools and teachers with funding to carry out international mobility projects with a variety of formative activities. The benefits of carrying out international mobility activities to strengthen student learning and teacher training are well known and have been researched or reported even from the early stages of a program that was born back in the 1980s but has always been focused on the university level. When considering teachers at early levels (schools and high schools), the 2014–2020 Erasmus+ program was the main source of funding to grant Spanish teachers permanent training activities abroad with a direct positive impact on their careers. The year 2020 is the last year of the first evolution of the Erasmus+ program, which has been renewed, extended, and strengthened for a new six-year term (2021–2027). However, 2020 has also been a significant year. The COVID-19 global pandemic continues to affect the mobility of citizens within the different territories of the union and, thus, have a direct negative impact on international teacher and student mobility. Being 2020 the end of a cycle and a critical moment, it is the perfect time to conduct an analysis of the data associated with the participation of teachers and schools in Spain, their perceptions of the program, the different activities carried out, and the impact of the pandemic. This research study is based on an analysis of an opinion survey through a nationwide sample of teachers participating in KA101 Erasmus+ projects. This paper gathers and presents data and conclusions using information previously not available that most of the time is published in official reports globally without considering the particularities of the different states of the European Union.


Author(s):  
Novita Sari ◽  
M. Saputra ◽  
Aswin Aswin ◽  
Avitha P ◽  
Mega C

Covid-19 merupakan penyakit pernapasan akut yang disebabkan oleh virus corona jenis baru. Penyakit ini pertama kali merebak di Wuhan, Cina lalu menyebar hampir ke seluruh dunia dan menyebabkan pandemi global. Penyakit ini menyerang semua golongan, dewasa, lansia, maupun anak-anak. Semua lapisan masyarakat dari mulai dewasa hingga anak-anak perlu mendapatkan edukasi yang mudah dipahami mengenai Covid19 dan cara-cara pencegahannya. Hal ini yang menjadi dasar dilaksanakannya praktek kerja pengabdian masyarakat IIB Darmajaya. Tujuan kegiatan ini adalah untuk ikut aktif dalam upaya pencegahan virus Covid-19 dengan memberikan sosialisasi tentang Covid-19 dan upaya pencegahannya melalui pembagian APD dan juga pembagian tempat cuci tangan kepada masyarakat Kelurahan Pinang Jaya, Kecamatan Kemiling, Kota Bandar Lampung. Kegiatan ini dilakukan bermitra dengan masyarakat Kelurahan Pinang Jaya . metode yang dipergunakan adalah dengan cara penyuluhan dan sosialisasi tentang pencegahan Covid-19, pengadaan  sarana prasarana pencegahan Covid 19. Hasil dari pengabdian ini adalah masyarakat dapat memahami lebih jauh mengenai virus Covid 19 ini sehingga masyarakat dapat turut serta melakukan upaya pencegahan penularan Covid-19 dimulai dari diri mereka masing-masing. Kata Kunci: Pengabdian, Covid-19, Pandemik, Sosialisasi, Edukasi ABSTRACT Covid-19 is an acute respiratory disease caused by a new type of corona virus. This disease first broke out in Wuhan, China then spread almost throughout the world and caused a global pandemic. This disease attacks all groups, adults, the elderly, and children. All levels of society from adults to children need to get education that is easy to understand about Covid19 and ways to prevent it. This is the basis for implementing IIB Darmajaya community service work practices. The purpose of this activity is to actively participate in efforts to prevent the Covid-19 virus by providing socialization about Covid-19 and prevention efforts through the distribution of PPE and also the distribution of hand washing facilities to the people of Pinang Jaya Village, Kemiling District, Bandar Lampung City. This activity is carried out in partnership with the people of Pinang Jaya Village. The method used is by means of counseling and socialization about the prevention of Covid-19, the provision of infrastructure for preventing Covid-19. of themselves. Keywords: Community Service, Covid-19, Pandemic, Socialization, Education


2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Fernando Freire Lisboa ◽  
Nathan Xavier Gomes ◽  
Pedro Arthur Nascimento Silva

Abstract   Achalasia is the main esophageal motility disorder and has a significant negative impact on the patient's quality of life. Achalasia patients have dysphagia and vomiting, often associated with chest pain, leading to significant weight loss. The treatment of achalasia should be primarily to decrease the pressure of the lower esophageal sphincter. There are different therapeutic options for the treatment, and laparoscopic myotomy is the standard treatment, despite the improvement of new techniques such as POEM. Methods Prospective and retrospective study carried out in a university hospital with 33 patients with achalasia, operated with the wide myotomy technique associated with modified Dor fundoplication, from January 2017 to November 2020. The diagnosis was made by clinical, endoscopic, radiological and manometric studies. Symptomatic assessment and therapeutic success were performed using the Eckardt score before and after the operation. Rezende's classification was used to classify the degree of megaesophagus. The degree of megaesophagus was correlated with the result of the technique. The results were analyzed using the IBM SPSS Statistics Version 26 software. Results Patients with idiopathic achalasia 28 (84.8%). Preoperative Eckardt score average 5.93 points, preoperative clinical stage I = 7 (21.2%), clinical stage II = 12 (36.4%) and clinical stage III = 14 (42.4%). 48-hour postoperative hospital stay. Average postoperative Eckardt score 0.30 points, with 32 (97%) clinical stage 0, and 1 (3%) in clinical stage I in the postoperative period. Remission rate of the disease after treatment 100%. There was no correlation between the degree of the megaesophagus with the preoperative symptoms or with the therapeutic result. There were no complications or need for reintervention. There were no reports of symptoms of GERD. Conclusion According to clinical, radiological and endoscopic data, the technique was considered safe and effective for the treatment and regression of achalasia symptoms in all degrees of megaesophagus in the present study. In addition, the technique was also effective as an anti-reflux mechanism, preventing the onset of symptoms of iatrogenic GERD.


2021 ◽  
pp. 17-19
Author(s):  
Priya Dalal ◽  
Atindra Narayan ◽  
Auditi Narayan ◽  
D.K. Sharma

Background: The demographic transition with ageing of population is a global phenomenon and in recent years there has been an increasing international awareness of health issues relating to aging population. Anemia represents an emerging global health problem producing a negative impact in the quality of life among the elderly and requiring greater allocation of health resources. Aims: To identify elderly patients with anemia and study the etiology, clinical parameters, laboratory parameters in these patients. Methods: A total of 100 patients were enrolled in this study. The entire medical history were obtained from each of the cases including previous medical reports and imaging studies. Complete blood counts , RBC indices,total WBC count, differential count, platelet count, haematocrit, ESR, peripheral smears ,reticulocyte count, ferritin, iron and TIBC were recorded for each patient. The data was compiled and analyzed using Statistical Package for social services (SPSS vs 20). Results: Among the etiologies, iron deciency anemia was seen in 43% of patients, anemia of chronic disease in 32%, anemia of chronic kidney disease and unexplained anemia in 11 % patients. Among clinical features the commonest symptom was easy fatiguability and commonest sign was pallor. Peripheral smear study showed that normocytic normochromic anemia was commonest type. Conclusion: This study showed that the commonest cause for anemia among elderly patients is iron deciency anemia followed by anemia due to chronic disease. Geriatric anemia is a disease that often goes unreported hence every effort should be made to identify the disease and evaluate the cause.


2019 ◽  
Vol 11 (11) ◽  
pp. 3194 ◽  
Author(s):  
Shihong Zeng ◽  
Xinwei Zhang ◽  
Xiaowei Wang ◽  
Guowang Zeng

Currently, China’s aging population, high savings rate and high housing asset prices coexist, which has become a hot issue in academic research. First, considering the life-cycle hypothesis and overlapping generations model, asset prices are negatively correlated with the population dependency ratio and positively correlated with household savings. Second, based on census data from prefecture-level cities, a pooled regression model and two-stage least squares (2SLS) are used in this empirical research. The child dependency ratio was found to have a significant negative impact on housing prices, while the elderly dependency ratio had a positive impact on housing prices. The positive relationship between household savings and housing prices is highly significant. Finally, the interaction analysis shows that the impact of population aging on housing prices differs under different levels of household savings; thus, population aging affects housing prices through household savings, and the mediator dilutes and weakens this impact. The elderly generation’s release of savings could gradually inhibit housing prices. Population aging causes long-run downside risks but not a market meltdown.


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