scholarly journals Evaluation of Gait Pattern and Lower Extremity Kinematics of Children with Morquio Syndrome (MPS IV)

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1350
Author(s):  
Jose J. Salazar-Torres ◽  
Chris Church ◽  
Thomas Shields ◽  
M. Wade Shrader ◽  
Lydia Fisher ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Genetic Disorder ◽  
Dynamic Assessment ◽  
Three Dimensional ◽  
Gait Pattern ◽  
Valgus Knee ◽  
Gait Patterns ◽  
Anterior Pelvic Tilt ◽  
Dimensional Measurements ◽  
Morquio Syndrome

Morquio syndrome (mucopolysaccharidosis IV/MPS IV) is a genetic disorder leading to skeletal abnormalities and gait deviations. Research on the gait patterns and lower extremity physical characteristics associated with skeletal dysplasia in children with MPS IV is currently limited. This research aimed to provide baseline gait patterns and lower limb skeletal alignment of children with MPS IV utilizing three-dimensional instrumented gait analysis. This Institutional Review Board-approved retrospective study evaluates the kinematics of the lower extremities of children with MPS IV during gait, comparing them with an age-matched group of typically developing children. Thirty-three children with MPS IV were included (8.6 ± 4.0 years old). Children with MPS IV walk with increased anterior pelvic tilt, knee valgus, knee flexion, external tibial torsion, and reduced walking speed and stride length (p < 0.001). Multiplanar abnormal alignment results in abnormal knee moments (p < 0.001). Limited correlations exist (r = 0.69–0.28) between dynamic three-dimensional measurements of knee varus/valgus and rotational alignment and traditional static two-dimensional measures (physical examination or radiographs) suggesting the possibility of knee instability during gait and the benefits of dynamic assessment.

Three-dimensional measurements of the lower extremity in children and adolescents using a low-dose biplanar X-ray device

2011 ◽  
Vol 22 (4) ◽  
pp. 765-771 ◽  
Author(s):  
Ramon Gheno ◽  
Eric Nectoux ◽  
Bernard Herbaux ◽  
Matteo Baldisserotto ◽  
Luiz Glock ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Children And Adolescents ◽  
Low Dose ◽  
Three Dimensional ◽  
X Ray ◽  
Dimensional Measurements

Evaluation of Gait Pattern and Lower Extremity Kinematics of Children with Morquio Syndrome (MPS IV)

2021 ◽  
Author(s):  
Jose Salazar-Torres ◽  
Chris Church ◽  
Thomas Shields ◽  
Wade Shrader ◽  
Stuart Mackenzie
Keyword(s):  
Lower Extremity ◽  
Gait Pattern ◽  
Morquio Syndrome

Gait pattern and lower extremity alignment in children with Morquio syndrome

2013 ◽  
Vol 22 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Arjun A. Dhawale ◽  
Chris Church ◽  
John Henley ◽  
Laurens Holmes ◽  
Mihir M. Thacker ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Gait Pattern ◽  
Lower Extremity Alignment ◽  
Morquio Syndrome

scholarly journals Three-Dimensional Human Gait Pattern: Reference Data for Young, Active Women Walking with Low, Preferred, and High Speeds

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Slawomir Winiarski ◽  
Jadwiga Pietraszewska ◽  
Bogdan Pietraszewski
Keyword(s):  
Reference Data ◽  
Three Dimensional ◽  
Gait Pattern ◽  
Human Gait ◽  
Specific Population ◽  
Gait Patterns ◽  
Normative Database ◽  
High Speeds ◽  
Normal Gait ◽  
Adjustment Of Parameters

Normal gait pattern is the key component in the investigation of pathological gait patterns. In computer motion analysis there is a need to include data from participants with different somatic structures to develop a normative database or to limit the database results to a specific population. The aim of this study was to determine kinematic gait patterns for young, active women walking with low, preferred, and self-selected speeds with regard to their somatic characteristics. Laboratory-based gait analysis was performed on 1320 gait cycles taken from 20 young, active women walking with three different speeds. Comprehensive anthropometric measurements and descriptive statistics were used to describe spatiotemporal and angular variables at each walking condition. The results demonstrated some significant differences in young, active women walking between different speeds and compared to the literature. This suggests that there is a need to include data from participants with different somatic structures to develop a normative database or limit the database results to a specific population. Detailed linear and angular kinematic variables allow for proper adjustment of parameters depending on the gait speed of people with locomotion disorders.

Study of Rehabilitation of Injured Knee Joint Applying Chaotic Theory in Human Body Motion

2007 ◽  
Vol 342-343 ◽  
pp. 581-584
Author(s):  
Byung Young Moon ◽  
Kwon Son ◽  
Jung Hong Park
Keyword(s):  
Time Series ◽  
Lyapunov Exponent ◽  
Angular Displacement ◽  
Three Dimensional ◽  
Gait Pattern ◽  
Body Motion ◽  
Largest Lyapunov Exponent ◽  
Chaos Analysis ◽  
Nonlinear Technique ◽  
Injured Knee

Gait analysis is essential to identify accurate cause and knee condition from patients who display abnormal walking. Traditional linear tools can, however, mask the true structure of motor variability, since biomechanical data from a few strides during the gait have limitation to understanding the system. Therefore, it is necessary to propose a more precise dynamic method. The chaos analysis, a nonlinear technique, focuses on understanding how variations in the gait pattern change over time. Healthy eight subjects walked on a treadmill for 100 seconds at 60 Hz. Three dimensional walking kinematic data were obtained using two cameras and KWON3D motion analyzer. The largest Lyapunov exponent from the measured knee angular displacement time series was calculated to quantify local stability. This study quantified the variability present in time series generated from gait parameter via chaos analysis. Gait pattern is found to be chaotic. The proposed Lyapunov exponent can be used in rehabilitation and diagnosis of recoverable patients.

Design of a 6-DOF Robotic Gait Training System With Closed-Chain Foot Initiated Kinematics Control

2015 ◽  
Author(s):  
Wei Liu ◽  
John Kovaleski ◽  
Marcus Hollis
Keyword(s):  
Three Dimensional ◽  
Computer Software ◽  
Gait Training ◽  
Gait Pattern ◽  
Training System ◽  
Normal Walking ◽  
Robot Assisted ◽  
Walking Gait ◽  
The Right ◽  
Joint Motions

Robotic assisted rehabilitation, taking advantage of neuroplasticity, has been shown to be helpful in regaining some degree of gait performance. Robot-applied movement along with voluntary efferent motor commands coordinated with the robot allows optimization of motion training. We present the design and characteristics of a novel foot-based 6-degree-of-freedom (DOF) robot-assisted gait training system where the limb trajectory mirrored the normal walking gait. The goal of this study was to compare robot-assisted gait to normal walking gait, where the limb moved independently without robotics. Motion analysis was used to record the three-dimensional kinematics of the right lower extremity. Walking motion data were determined and transferred to the robotic motion application software for inclusion in the robotic trials where the robot computer software was programmed to produce a gait pattern in the foot equivalent to the gait pattern recorded from the normal walking gait trial. Results demonstrated that ankle; knee and hip joint motions produced by the robot are consistent with the joint motions in walking gait. We believe that this control algorithm provides a rationale for use in future rehabilitation, targeting robot-assisted training in people with neuromuscular disabilities such as stroke.

scholarly journals IMG-07. GADOLINIUM IS NOT NECESSARY FOR SURVEILLANCE MR IMAGING IN CHILDREN WITH CHIASMATIC-HYPOTHALAMIC LOW GRADE GLIOMA

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii356-iii356
Author(s):  
Fatema Malbari ◽  
Murali Chintagumpala ◽  
Jack Su ◽  
Mehmet Okcu ◽  
Frank Lin ◽  
...  
Keyword(s):  
Metastatic Disease ◽  
Three Dimensional ◽  
Low Grade Glioma ◽  
Cancer Center ◽  
Low Grade ◽  
Contrast Imaging ◽  
Post Contrast ◽  
Best Response ◽  
Dimensional Measurements ◽  
Initiation Of Therapy

Abstract BACKGROUND Patients with chiasmatic-hypothalamic low grade glioma (CHLGG) have frequent MRIs with gadolinium based contrast agents (GBCA) for disease monitoring. Cumulative gadolinium deposition in children is a potential concern. The purpose of this research is to establish whether MRI with GBCA is necessary for determining tumor progression in children with CHLGG. METHODS Children with progressive CHLGG were identified from Texas Children’s Cancer Center between 2005–2019. Pre- and post-contrast MRI sequences were separately reviewed by one neuroradiologist who was blinded to the clinical course. Three dimensional measurements and tumor characteristics were collected. Radiographic progression was defined as a 25% increase in size (product of two largest dimensions) compared to baseline or best response after initiation of therapy. RESULTS A total of 28 patients with progressive CHLGG including 683 MRIs with GBCA (mean 24 MRIs/patient; range: 10–43 MRIs) were reviewed. No patients had a diagnosis of NF1. Progression was observed 92 times, 91 (98.9%) on noncontrast and 90 (97.8%) on contrast imaging. Sixty-seven radiographic and/or clinical progressions necessitating management changes were identified in all (100%) noncontrast sequences and 66 (98.5%) contrast sequences. Tumor growth &gt;2 mm in any dimension was identified in 184/187(98.4%) on noncontrast and 181/187(96.8%) with contrast imaging. Non primary metastatic disease was seen in seven patients (25%), which were better visualized on contrast imaging in 4 (57%). CONCLUSION MRI without GBCA effectively identifies patients with progressive disease. One should consider eliminating contrast in imaging of children with CHLGG with GBCA reserved for monitoring those with metastatic disease.

scholarly journals Three-Dimensional Measurements of Micro- to Nanometer-Scale Features at and Below the Surface Using Scanning Electron Microscopy

2011 ◽  
Vol 17 (S2) ◽  
pp. 992-993
Author(s):  
M Zhao ◽  
B Ming ◽  
P Kavuri ◽  
A Vladár
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Three Dimensional ◽  
Nanometer Scale ◽  
Dimensional Measurements ◽  
Scanning Electron

Extended abstract of a paper presented at Microscopy and Microanalysis 2011 in Nashville, Tennessee, USA, August 7–August 11, 2011.

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