scholarly journals Application of Supervised Machine Learning to Recognize Competent Level and Mixed Antinuclear Antibody Patterns Based on ICAP International Consensus

Diagnostics ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 642
Author(s):  
Yi-Da Wu ◽  
Ruey-Kai Sheu ◽  
Chih-Wei Chung ◽  
Yen-Ching Wu ◽  
Chiao-Chi Ou ◽  
...  

Background: Antinuclear antibody pattern recognition is vital for autoimmune disease diagnosis but labor-intensive for manual interpretation. To develop an automated pattern recognition system, we established machine learning models based on the International Consensus on Antinuclear Antibody Patterns (ICAP) at a competent level, mixed patterns recognition, and evaluated their consistency with human reading. Methods: 51,694 human epithelial cells (HEp-2) cell images with patterns assigned by experienced medical technologists collected in a medical center were used to train six machine learning algorithms and were compared by their performance. Next, we choose the best performing model to test the consistency with five experienced readers and two beginners. Results: The mean F1 score in each classification of the best performing model was 0.86 evaluated by Testing Data 1. For the inter-observer agreement test on Testing Data 2, the average agreement was 0.849 (?) among five experienced readers, 0.844 between the best performing model and experienced readers, 0.528 between experienced readers and beginners. The results indicate that the proposed model outperformed beginners and achieved an excellent agreement with experienced readers. Conclusions: This study demonstrated that the developed model could reach an excellent agreement with experienced human readers using machine learning methods.

Author(s):  
K. Anurag Reddy ◽  
Susant Kumar Rath ◽  
Advin Manhar

The recent outbreak of the respiratory ailment COVID-19 caused by novel corona virus SARS- Cov2 is a severe and urgent global concern. In the absence of vaccine, and also treatment of COVID- 19 WHO (World Health Organization) had informed that Social distancing is the only way to avoid this pandemic and also made clear that Prevention is better than Cure. The main containment strategy is to reduce the contagion by the isolation of affected individuals. Earlier stage this pandemic was declared as a sort of Pneumonia where an individual gets affected by cold, fever and headache. Later, some new symptoms are seen in affected people like sore throat, breathing problems, and sometimes constipation. To make rapid decisions on treatment, and isolation needs, it would be useful to determine which symptoms presented by suspected infection cases are the best predictors of a positive diagnosis. This can be done by analyzing patient's symptoms and its outcome. Here, we developed a model that employed supervised machine learning algorithms to identify the certain features predicting COVID-19 disease diagnosis with high accuracy. Features examined includes details of the concerned individual, e.g., age, gender, observation of fever, breathing difficulty, and clinical details such as the severity of cough and incidence of lung infection and congestion. We had implemented some Machine Learning techniques with algorithms and found out the highest accuracy more than (50 %) of individual patient for all age groups. The following data is collected from COVID-19 positive patients, online survey and social survey done at testing centres. After that we had applied various methods as Data Preprocessing, Model Validation and Statistical analysis, etc. The probability and accuracy of a patient is shown in using various methods of Machine learning algorithm for a better understanding.


2020 ◽  
Vol 14 (2) ◽  
pp. 140-159
Author(s):  
Anthony-Paul Cooper ◽  
Emmanuel Awuni Kolog ◽  
Erkki Sutinen

This article builds on previous research around the exploration of the content of church-related tweets. It does so by exploring whether the qualitative thematic coding of such tweets can, in part, be automated by the use of machine learning. It compares three supervised machine learning algorithms to understand how useful each algorithm is at a classification task, based on a dataset of human-coded church-related tweets. The study finds that one such algorithm, Naïve-Bayes, performs better than the other algorithms considered, returning Precision, Recall and F-measure values which each exceed an acceptable threshold of 70%. This has far-reaching consequences at a time where the high volume of social media data, in this case, Twitter data, means that the resource-intensity of manual coding approaches can act as a barrier to understanding how the online community interacts with, and talks about, church. The findings presented in this article offer a way forward for scholars of digital theology to better understand the content of online church discourse.


2021 ◽  
Vol 1916 (1) ◽  
pp. 012042
Author(s):  
Ranjani Dhanapal ◽  
A AjanRaj ◽  
S Balavinayagapragathish ◽  
J Balaji

Author(s):  
David Blondheim

AbstractMachine learning (ML) is unlocking patterns and insight into data to provide financial value and knowledge for organizations. Use of machine learning in manufacturing environments is increasing, yet sometimes these applications fail to produce meaningful results. A critical review of how defects are classified is needed to appropriately apply machine learning in a production foundry and other manufacturing processes. Four elements associated with defect classification are proposed: Binary Acceptance Specifications, Stochastic Formation of Defects, Secondary Process Variation, and Visual Defect Inspection. These four elements create data space overlap, which influences the bias associated with training supervised machine learning algorithms. If this influence is significant enough, the predicted error of the model exceeds a critical error threshold (CET). There is no financial motivation to implement the ML model in the manufacturing environment if its error is greater than the CET. The goal is to bring awareness to these four elements, define the critical error threshold, and offer guidance and future study recommendations on data collection and machine learning that will increase the success of ML within manufacturing.


2021 ◽  
Vol 11 (15) ◽  
pp. 6728
Author(s):  
Muhammad Asfand Hafeez ◽  
Muhammad Rashid ◽  
Hassan Tariq ◽  
Zain Ul Abideen ◽  
Saud S. Alotaibi ◽  
...  

Classification and regression are the major applications of machine learning algorithms which are widely used to solve problems in numerous domains of engineering and computer science. Different classifiers based on the optimization of the decision tree have been proposed, however, it is still evolving over time. This paper presents a novel and robust classifier based on a decision tree and tabu search algorithms, respectively. In the aim of improving performance, our proposed algorithm constructs multiple decision trees while employing a tabu search algorithm to consistently monitor the leaf and decision nodes in the corresponding decision trees. Additionally, the used tabu search algorithm is responsible to balance the entropy of the corresponding decision trees. For training the model, we used the clinical data of COVID-19 patients to predict whether a patient is suffering. The experimental results were obtained using our proposed classifier based on the built-in sci-kit learn library in Python. The extensive analysis for the performance comparison was presented using Big O and statistical analysis for conventional supervised machine learning algorithms. Moreover, the performance comparison to optimized state-of-the-art classifiers is also presented. The achieved accuracy of 98%, the required execution time of 55.6 ms and the area under receiver operating characteristic (AUROC) for proposed method of 0.95 reveals that the proposed classifier algorithm is convenient for large datasets.


2021 ◽  
Vol 11 (10) ◽  
pp. 4443
Author(s):  
Rokas Štrimaitis ◽  
Pavel Stefanovič ◽  
Simona Ramanauskaitė ◽  
Asta Slotkienė

Financial area analysis is not limited to enterprise performance analysis. It is worth analyzing as wide an area as possible to obtain the full impression of a specific enterprise. News website content is a datum source that expresses the public’s opinion on enterprise operations, status, etc. Therefore, it is worth analyzing the news portal article text. Sentiment analysis in English texts and financial area texts exist, and are accurate, the complexity of Lithuanian language is mostly concentrated on sentiment analysis of comment texts, and does not provide high accuracy. Therefore in this paper, the supervised machine learning model was implemented to assign sentiment analysis on financial context news, gathered from Lithuanian language websites. The analysis was made using three commonly used classification algorithms in the field of sentiment analysis. The hyperparameters optimization using the grid search was performed to discover the best parameters of each classifier. All experimental investigations were made using the newly collected datasets from four Lithuanian news websites. The results of the applied machine learning algorithms show that the highest accuracy is obtained using a non-balanced dataset, via the multinomial Naive Bayes algorithm (71.1%). The other algorithm accuracies were slightly lower: a long short-term memory (71%), and a support vector machine (70.4%).


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