scholarly journals Special Issue “Diagnostic Biomarkers in Prostate Cancer 2020”

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 505
Author(s):  
Jochen Neuhaus
Keyword(s):  
Prostate Cancer ◽  
Cancer Biomarkers ◽  
Special Issue ◽  
Diagnostic Biomarkers ◽  
Urologic Research

The search for novel prostate cancer biomarkers is one of the major topics in recent urologic research [...]

scholarly journals Identification of prostate cancer biomarkers in urinary exosomes

Oncotarget ◽  
2015 ◽  
Vol 6 (30) ◽  
pp. 30357-30376 ◽  
Author(s):  
Anders Øverbye ◽  
Tore Skotland ◽  
Christian J. Koehler ◽  
Bernd Thiede ◽  
Therese Seierstad ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Biomarkers ◽  
Urinary Exosomes

Diagnostic biomarkers of prostate cancer

2010 ◽  
Vol 45 (1) ◽  
pp. 60-67 ◽  
Author(s):  
Lars Häggarth ◽  
Christina Hägglöf ◽  
Sara Jonmarker Jaraj ◽  
Kenneth Wester ◽  
Fredrik Pontén ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diagnostic Biomarkers

scholarly journals A Model for the Design and Construction of a Resource for the Validation of Prognostic Prostate Cancer Biomarkers

2013 ◽  
Vol 20 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Sarah Hawley ◽  
Ladan Fazli ◽  
Jesse K. McKenney ◽  
Jeff Simko ◽  
Dean Troyer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Biomarkers ◽  
Design And Construction

scholarly journals Nucleases as molecular targets for cancer diagnosis

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Alien Balian ◽  
Frank J. Hernandez
Keyword(s):  
Enzymatic Activity ◽  
Cancer Diagnosis ◽  
Essential Feature ◽  
Treatment Options ◽  
Cancer Biomarkers ◽  
Diagnostic Biomarkers ◽  
Early Cancer Diagnosis ◽  
Novel Biomarkers ◽  
Made In

AbstractEarly cancer diagnosis is a crucial element to improved treatment options and survival. Great research efforts have been made in the search for better performing cancer diagnostic biomarkers. However, the quest continues as novel biomarkers with high accuracy for an early diagnosis remain an unmet clinical need. Nucleases, which are enzymes capable of cleaving nucleic acids, have been long considered as potential cancer biomarkers. The implications of nucleases are key for biological functions, their presence in different cellular counterparts and catalytic activity led the enthusiasm towards investigating the role of nucleases as promising cancer biomarkers. However, the most essential feature of these proteins, which is their enzymatic activity, has not been fully exploited. This review discusses nucleases interrogated as cancer biomarkers, providing a glimpse of their physiological roles. Moreover, it highlights the potential of harnessing the enzymatic activity of cancer-associated nucleases as a novel diagnostic biomarker using nucleic acid probes as substrates.

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