scholarly journals Primary Cardiac Intimal Sarcoma Visualized on 2-[18F]FDG PET/CT

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 718
Author(s):  
Kim Francis Andersen ◽  
Nahid Sharghi Someh ◽  
Annika Loft ◽  
Jane Maestri Brittain
Keyword(s):  
Fdg Pet ◽  
Correct Diagnosis ◽  
Left Ventricular ◽  
Cardiac Tumors ◽  
Mesenchymal Tumors ◽  
Congenital Aortic Stenosis ◽  
Intimal Sarcoma ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Primary cardiac tumors are extremely rare, with an incidence of 0.001–0.03%. Twenty-five percent of these tumors are malignant, with sarcomas accounting for approximately 95%. Cardiac intimal sarcoma is the least reported subtype of primary cardiac sarcoma. These endocardial mesenchymal tumors most often arise from great arterial vessels, and are rarely located in the heart. They often present with an aggressive clinical course and have a poor prognosis, with surgical resection with achievement of free margins being the mainstay of treatment. This emphasizes the importance of an early, correct diagnosis and timely intervention. We report a 60-year-old Caucasian male with several former cardiac surgical procedures due to congenital aortic stenosis, presenting with functional mitral stenosis/insufficiency and left ventricular outflow tract obstruction (LVOTO) due to massive masses in the left ventricle and atrium of the heart. Hybrid imaging with 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography (2-[18F]FDG PET/CT) was performed prior to surgery to characterize the intracardiac masses and estimate tumor burden, as well as to identify a potential extracardiac primary malignancy.

scholarly journals Molecular Imaging with 18F-FDG PET/CT and 99mTc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1355
Author(s):  
Adrien Holzgreve ◽  
Matthias P. Fabritius ◽  
Thomas Knösel ◽  
Lena M. Mittlmeier ◽  
Johannes Rübenthaler ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Fdg Pet ◽  
Correct Diagnosis ◽  
Osteitis Fibrosa ◽  
Osteitis Fibrosa Cystica ◽  
Pet Ct ◽  
Brown Tumors ◽  
18F Fdg ◽  
99Mtc Mibi ◽  
Fdg Pet Ct

Benign so-called “brown tumors” secondary to hyperparathyroidism are a rare diagnostic pitfall due to their impressively malignant-like character in various imaging modalities. We present the case of a 65-year-old male patient with multiple unclear osteolytic lesions on prior imaging suspicious for metastatic malignant disease. Eventually, findings of 18F-FDG PET/CT staging and 99mTc-MIBI scintigraphy resulted in revision of the initially suspected malignant diagnosis. This case illustrates how molecular imaging findings non-invasively corroborate the correct diagnosis of osteitis fibrosa cystica generalisata with the formation of multiple benign brown tumors.

Left Ventricular Infected Thrombus Detected by 18F-FDG PET/CT and MRI in Disseminated Staphylococcus Infection

2020 ◽  
Vol 45 (12) ◽  
pp. 957-959
Author(s):  
Ana María García Vicente ◽  
Miguel Villar García ◽  
José Javier Blanch Sancho ◽  
Ángel Soriano Castrejón
Keyword(s):  
Fdg Pet ◽  
Left Ventricular ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Ct And Mri

Prolonged back pain attributed to suspected spondylodiscitis

2012 ◽  
Vol 51 (05) ◽  
pp. 194-200 ◽  
Author(s):  
L. Rettenbacher ◽  
C. Thaler ◽  
J. Holzmannhofer ◽  
M. Mc Coy ◽  
C. Pirich ◽  
...  
Keyword(s):  
Back Pain ◽  
Fdg Pet ◽  
Visual Analysis ◽  
Chronic Back Pain ◽  
Correct Diagnosis ◽  
Standardized Uptake Value ◽  
Pet Ct ◽  
18F Fdg ◽  
Sensitivity Specificity ◽  
Fdg Pet Ct

Summary Objective: This study aimed at investigating the diagnostic value of 18F-FDG PET/CT in cases of suspected spondylodiscitis after inconclusive results in initial diagnostic imaging. Patients, methods: We analysed 38 consecutive cases of suspected spondylodiscitis (mean age: 67 ± 14 years) with chronic back pain referred to our Department during a fouryear- period after inconclusive results in MRI or other conventional modalities. Clinical histories were retrospectively worked up and results of 18F-FDG PET/CT and MRI were analysed and related to the results of biopsy, blood culture and a one-year clinical followup. 18F-FDG PET/CT was analysed qualitatively by visual analysis and quantitatively. We measured the maximum standardized uptake value (SUVmax) in the region of back pain and in a corresponding reference region (RR) in each patient and calculated a SUVmax-ratio. Results: 22/38 patients had confirmed spondylodiscitis, while 16 were negative. 18F-FDG PET/CT established a correct diagnosis in 34 out of 38 patients by visual analysis. 18F-FDG PET/CT reached a sensitivity, specificity and accuracy of 81.8%, 100%, 89.5% and a PPV and NPV of 100% and 80%. MRI, performed in 27 patients reached a sensitivity, specificity and accuracy of 75%, 71.4%, 74.1% and a PPV and NPV of 88.2% and 50%. Patients with confirmed spondylodiscitis showed a significantly (p < 0.05) higher SUVmax of 5.1 ± 1.9 and SUVmax-ratio of 1.9 ± 0.8 than patients without it (SUVmax (3.8 ± 1.5), SUVmaxratio (1.2 ± 0.3). Conclusion: 18F-FDG PET/CT provided diagnostic information in most patients with chronic back pain and suspected spondylodiscitis. It was helpful in establishing a correct diagnosis in challenging cases of spondylodiscitis with mostly unclear findings in previous MRI.

scholarly journals Differentiation of Malignant and Benign Cardiac Tumors Using 18F-FDG PET/CT

2012 ◽  
Vol 53 (6) ◽  
pp. 856-863 ◽  
Author(s):  
K. Rahbar ◽  
H. Seifarth ◽  
M. Schafers ◽  
L. Stegger ◽  
A. Hoffmeier ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Cardiac Tumors ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Pedunculated pulmonary artery intimal sarcoma with poor uptake in 18F-FDG PET/CT: A case report

2021 ◽  
Author(s):  
Takumi Takauchi ◽  
Ryosuke Murai ◽  
Kazunori Musiake ◽  
Yoko Akaike ◽  
Masaya Hirayama ◽  
...  
Keyword(s):  
Case Report ◽  
Pulmonary Artery ◽  
Fdg Pet ◽  
Intimal Sarcoma ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

The key role of 18F-FDG PET/CT for correct diagnosis, staging, and treatment in a patient with simultaneous NPC and TB lymphadenitis: case report

2016 ◽  
Vol 102 (2_suppl) ◽  
pp. S22-S25 ◽  
Author(s):  
Renato Micera ◽  
Nicola Simoni ◽  
Mario De Liguoro ◽  
Federica Vigo ◽  
Claudia Grondelli ◽  
...  
Keyword(s):  
Case Report ◽  
Fdg Pet ◽  
Correct Diagnosis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Assessment of cardiac tumors by 18F-FDG PET/CT imaging: Histological correlation and clinical outcomes

2020 ◽  
Author(s):  
Jingjing Meng ◽  
Honglei Zhao ◽  
Yongmin Liu ◽  
Dong Chen ◽  
Marcus Hacker ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Fdg Pet ◽  
Ct Imaging ◽  
Cardiac Tumors ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Right Atrial Intimal Sarcoma on 18F-FDG PET/CT

2020 ◽  
Vol 45 (7) ◽  
pp. e307-e308
Author(s):  
Nick Janssen ◽  
Jef Verheyen ◽  
Adrien Albert
Keyword(s):  
Fdg Pet ◽  
Right Atrial ◽  
Intimal Sarcoma ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

P1806Diagnosis of isolated cardiac sarcoidosis using FDG-PET/CT on the basis of new guidelines

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
H Kawai ◽  
M Sarai ◽  
Y Kato ◽  
H Naruse ◽  
J Ishii ◽  
...  
Keyword(s):  
Predictive Value ◽  
Fdg Pet ◽  
Cardiac Sarcoidosis ◽  
Left Ventricular ◽  
Diagnosis And Treatment ◽  
Fdg Uptake ◽  
Pet Ct ◽  
18F Fdg ◽  
New Guidelines ◽  
Fdg Pet Ct

Abstract Introduction Sarcoidosis is a systemic inflammatory disease which can involve any organs. The reported prevalence of isolated cardiac sarcoidosis (CS) varies widely because of the lack of an agreed definition of isolated CS (iCS). ICS was newly defined in the new guidelines for CS by Japanese Circulation Society. Purpose We aimed to examine the diagnostic accuracy of 18F-FDG PET/CT and the ratio of iCS in the whole CS by reviewing the patients with suspected CS undergoing the whole-body and cardiac FDG PET/CT scans. Methods We retrospectively reviewed 74 consecutive patients undergoing 18F-FDG PET/CT from 2013 to 2018 (mean age 60±14 years, 37 male) without the initiation of corticosteroid. Myocardial FDG uptake in CS was defined as a “focal” or “focal on diffuse” pattern. Systemic sarcoidosis (sCS) and iCS were diagnosed according to guidelines for the diagnosis and treatment of CS by Japanese Circulation Society. In short, iCS was diagnosed clinically when no clinical findings of sarcoidosis in any other organs and FDG uptake in heart were shown in addition to the following three of four criteria: high-grade atrioventricular block or fatal ventricular arrhythmia, structural abnormality, left ventricular contractile dysfunction, and delayed Gadolinium enhancement of myocardium on MRI. Results Of 31 patients with extra-cardiac sarcoidosis, 10 already met the diagnostic criteria of sCS before undergoing 18F-FDG PET/CT and 11 was newly diagnosed as sCS after FDG PET/CT. Of the remaining 43 without extra-cardiac sarcoidosis, 18 had FDG uptake in heart. Of 18 with FDG uptake in heart, iCS was diagnosed in 7, and sCS in 3 with extra-cardiac uptake of FDG as well as myocardium. Finally, 24 and 7 patients met the criteria of sCS and iCS based on the guideline, respectively. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FDG PET/CT for CS including sCS and iCS were 90, 87, 88, 85, and 92%, respectively. Conclusion The ratio of iCS on the basis of new guidelines for diagnosis and treatment of CS was 22% of the whole CS.

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