scholarly journals The Terebelliformia-Recent Developments and Future Directions

Diversity ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 60 ◽  
Author(s):  
Pat Hutchings ◽  
Orlemir Carrerette ◽  
João M. M. Nogueira ◽  
Stephane Hourdez ◽  
Nicolas Lavesque
Keyword(s):  
Deep Sea ◽  
Current Knowledge ◽  
Knowledge Gaps ◽  
Future Directions ◽  
Large Group ◽  
Deposit Feeders ◽  
Species Complexes ◽  
Recent Developments ◽  
Biogeographic Regions ◽  
New Methodologies

Terebelliformia comprises a large group of sedentary polychaetes which live from the intertidal to the deep sea. The majority live in tubes and are selective deposit feeders. This study synthesises the current knowledge of this group, including their distribution, in the different biogeographic regions. We highlight the new methodologies being used to describe them and the resolution of species complexes occurring in the group. The main aim of this review is to highlight the knowledge gaps and to stimulate research in those directions, which will allow for knowledge of their distribution and abundances to be used by ecologists and managers.

Lepidoptera genomes: current knowledge, gaps and future directions

2018 ◽  
Vol 25 ◽  
pp. 99-105 ◽  
Author(s):  
Deborah A Triant ◽  
Scott D Cinel ◽  
Akito Y Kawahara
Keyword(s):  
Current Knowledge ◽  
Knowledge Gaps ◽  
Future Directions

scholarly journals Multiscale plant modeling: from genome to phenome and beyond

2021 ◽  
Author(s):  
Megan L. Matthews ◽  
Amy Marshall-Colón
Keyword(s):  
Multiscale Modeling ◽  
Vertical Integration ◽  
Current Knowledge ◽  
Emergent Properties ◽  
Biological Organization ◽  
Multiscale Models ◽  
Future Directions ◽  
Recent Developments ◽  
Multiple Levels ◽  
Microbial Systems

Plants are complex organisms that adapt to changes in their environment using an array of regulatory mechanisms that span across multiple levels of biological organization. Due to this complexity, it is difficult to predict emergent properties using conventional approaches that focus on single levels of biology such as the genome, transcriptome, or metabolome. Mathematical models of biological systems have emerged as useful tools for exploring pathways and identifying gaps in our current knowledge of biological processes. Identification of emergent properties, however, requires their vertical integration across biological scales through multiscale modeling. Multiscale models that capture and predict these emergent properties will allow us to predict how plants will respond to a changing climate and explore strategies for plant engineering. In this review, we (1) summarize the recent developments in plant multiscale modeling; (2) examine multiscale models of microbial systems that offer insight to potential future directions for the modeling of plant systems; (3) discuss computational tools and resources for developing multiscale models; and (4) examine future directions of the field.

scholarly journals Quality of Care for Acute Kidney Disease: Current Knowledge Gaps and Future Directions

2020 ◽  
Vol 5 (10) ◽  
pp. 1634-1642
Author(s):  
Kathleen D. Liu ◽  
Lui G. Forni ◽  
Michael Heung ◽  
Vin-Cent Wu ◽  
John A. Kellum ◽  
...  
Keyword(s):  
Quality Of Care ◽  
Kidney Disease ◽  
Current Knowledge ◽  
Knowledge Gaps ◽  
Future Directions ◽  
Acute Kidney Disease

scholarly journals Knowledge sharing about deep-sea ecosystems to inform conservation and research decisions

FACETS ◽  
2017 ◽  
Vol 2 (2) ◽  
pp. 984-997 ◽  
Author(s):  
Stephanie R. Januchowski-Hartley ◽  
Kimberly A. Selkoe ◽  
Natalya D. Gallo ◽  
Christopher E. Bird ◽  
J. Derek Hogan
Keyword(s):  
Decision Making ◽  
Deep Sea ◽  
Time Series Data ◽  
Current Knowledge ◽  
Series Data ◽  
Monitoring Networks ◽  
Drivers Of Change ◽  
Knowledge Gaps ◽  
Depth Interviews ◽  
Anthropogenic Drivers

The Marianas Trench Marine National Monument (MNM) currently extends policy-based protection to deep-sea ecosystems contained within it, but managers require better understanding of the current knowledge and knowledge gaps about these ecosystems to guide decision-making. To address this need, we present a case study of the Marianas Trench MNM using in-depth interviews to determine scientists’ (1) current understanding of anthropogenic drivers of change and system vulnerability in deep-sea ecosystems; and (2) perceptions of the least understood deep-sea ecosystems and processes in the Marianas Trench MNM, and which of these, if any, should be research priorities to fill knowledge gaps about these systems and the impacts from anthropogenic drivers of change. Interview respondents shared similar views on the current knowledge of deep-sea ecosystems and potential anthropogenic drivers of change in the Marianas Trench MNM. Respondents also identified trench and deep pelagic (bathyal, abyssal, and hadal zones) ecosystems as the least understood, and highlighted climate change, litter and waste, mining and fishing, and interactions between these drivers of change as critical knowledge gaps. To fill key knowledge gaps and inform conservation decision-making, respondents identified the need for monitoring networks and time-series data. Our approach demonstrates how in-depth interviews can be used to elicit knowledge to inform decision-making in data-limited situations.

scholarly journals Panel: Research Sponsors for Cybersecurity Research and the Human Factor

2019 ◽  
Vol 63 (1) ◽  
pp. 422-426
Author(s):  
Robert S. Gutzwiller ◽  
Dan Cosley ◽  
Kimberly Ferguson-Walter ◽  
Dustin Fraze ◽  
Robert Rahmer
Keyword(s):  
Human Factor ◽  
Current Knowledge ◽  
The State ◽  
Knowledge Gaps ◽  
Future Directions ◽  
State Of The Field

A panel of past or current sponsors of human-centered research in cybersecurity. Attendees from industry, government and academia alike who are interested in cybersecurity research will benefit from hearing these panelists describe their experience and their views on the state of the field, current knowledge gaps and future directions for winning proposals.

Green Synthesized Nanomaterials as Theranostic Platforms for Cancer Treatment: Principles, Challenges and the Road Ahead

2019 ◽  
Vol 26 (8) ◽  
pp. 1311-1327 ◽  
Author(s):  
Pala Rajasekharreddy ◽  
Chao Huang ◽  
Siddhardha Busi ◽  
Jobina Rajkumari ◽  
Ming-Hong Tai ◽  
...  
Keyword(s):  
Nanoparticle Synthesis ◽  
Research Field ◽  
Synthesis Methods ◽  
Synthetic Approach ◽  
Future Directions ◽  
The Road ◽  
New Methods ◽  
Recent Developments ◽  
Theranostic Applications ◽  
Insight Into

With the emergence of nanotechnology, new methods have been developed for engineering various nanoparticles for biomedical applications. Nanotheranostics is a burgeoning research field with tremendous prospects for the improvement of diagnosis and treatment of various cancers. However, the development of biocompatible and efficient drug/gene delivery theranostic systems still remains a challenge. Green synthetic approach of nanoparticles with low capital and operating expenses, reduced environmental pollution and better biocompatibility and stability is a latest and novel field, which is advantageous over chemical or physical nanoparticle synthesis methods. In this article, we summarize the recent research progresses related to green synthesized nanoparticles for cancer theranostic applications, and we also conclude with a look at the current challenges and insight into the future directions based on recent developments in these areas.

Free Fatty Acid Receptors as New Potential Targets in Colorectal Cancer

2020 ◽  
Vol 21 (14) ◽  
pp. 1397-1404
Author(s):  
Adrian Bartoszek ◽  
Jakub Fichna ◽  
Aleksandra Tarasiuk ◽  
Agata Binienda ◽  
Adam Fabisiak ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Current Knowledge ◽  
Developed Countries ◽  
Future Directions ◽  
Screening Programs ◽  
Pharmacological Targets ◽  
The Family ◽  
Free Fatty Acid Receptors

Colorectal cancer (CRC) is one of the most common cancers worldwide. In developed countries, its mortality remains high, yet the prevalence has established owing to effective screening programs; however due to the westernization of lifestyle, the incidences in many other countries have increased. Although the treatment of CRC has improved in the last few years, the side effects of these approaches cannot be neglected. Recently, members of the family of free fatty acid receptors (FFARs) have become attractive pharmacological targets in many diseases, including asthma; studies also point to their role in carcinogenesis. Here, we discuss current knowledge and future directions in FFAR research related to CRC. Contradictory results of FFARs modulation may derive from the pleiotropic effects of FFAR ligands, receptor distribution and different signal transduction. Hence, we indicate directions of further studies to fully use the potential of FFARs in CRC.

Alcohol Consumption and Risk of Uterine Fibroids

2020 ◽  
Vol 20 (4) ◽  
pp. 247-258 ◽  
Author(s):  
Hajra Takala ◽  
Qiwei Yang ◽  
Ahmed M. Abd El Razek ◽  
Mohamed Ali ◽  
Ayman Al-Hendy
Keyword(s):  
Alcohol Consumption ◽  
Animal Studies ◽  
Molecular Mechanisms ◽  
Legal Status ◽  
Current Knowledge ◽  
Uterine Fibroids ◽  
Future Directions ◽  
Working Adults ◽  
The Us ◽  
Alcohol Related Problems

Lifestyle factors, such as alcohol intake, have placed a substantial burden on public health. Alcohol consumption is increasing globally due to several factors including easy accessibility of this addictive substance besides its legal status and social acceptability. In the US, alcohol is the third leading preventable cause of death (after tobacco, poor diet and physical inactivity) with an estimated 88,000 people dying from alcohol-related causes annually, representing 1 in 10 deaths among working adults. Furthermore, the economic burden of excess drinking costs the US around $249 billion ($191.1 billion related to binge drinking). Although men likely drink more than women do, women are at much higher risk for alcohol-related problems. Alcohol use is also considered to be one of the most common non-communicable diseases, which affects reproductive health. This review article summarizes the current knowledge about alcohol-related pathogenesis of uterine fibroids (UFs) and highlights the molecular mechanisms that contribute to the development of UFs in response to alcohol consumption. Additionally, the effect of alcohol on the levels of various factors that are involved in UFs pathogenesis, such as steroid hormones, growth factors and cytokines, are summarized in this review. Animal studies of deleterious alcohol effect and future directions are discussed as well.

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