scholarly journals Seaweed Biodiversity of India: Reviewing Current Knowledge to Identify Gaps, Challenges, and Opportunities

Diversity ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 13 ◽  
Author(s):  
Vaibhav A. Mantri ◽  
Monica Gajanan Kavale ◽  
Mudassar Anisoddin Kazi
Keyword(s):  
Current Knowledge ◽  
Coastal Pollution ◽  
Marine Resources ◽  
Economic Potential ◽  
Present Communication ◽  
Precise Information ◽  
Conservation Implications ◽  
Challenges And Opportunities ◽  
The Status ◽  
High Conservation

Seaweeds are a renewable marine resources and have not yet received considerable attention in the field of taxonomy in India as compared to their terrestrial counterparts, essentially due to the lack of awareness of their economic potential. Although the recent inventory from the Indian region documented the presence of approximately 865 seaweed taxa, of which only a few are taxonomically well characterized, more precise information still awaits with respect to microscopic and molecular examinations of many. Thus far, in terms of spatial extent, probably only a few of the total hospitable seaweed habitats have been explored, and large portions, including island territories and subtidal waters, remain virtually untouched. Surveying those may lead to the reporting of several taxa new to science. Furthermore, more focused efforts are required to understand the endemic and endangered taxa which have high conservation implications. Considering the unprecedented pressures seaweeds are facing, including coastal pollution and human-induced global warming, it is critical to reinforce our knowledge of seaweed biodiversity. In the present communication, we intended to address the status of seaweed biodiversity in India along with the gaps, challenges, and opportunities.

Status of Conservation and Decline of Amphibians

2018 ◽  
Keyword(s):  
Environmental Changes ◽  
Current Knowledge ◽  
Conservation Status ◽  
Warning System ◽  
Amphibian Declines ◽  
Current Conservation ◽  
The Pacific ◽  
Challenges And Opportunities ◽  
The Status ◽  
The Impact

Amphibians are among the most threatened groups of animals on earth. In part due to their highly permeable skin, amphibians are highly sensitive to environmental changes and pollution and provide an early-warning system of deteriorating environmental conditions. The more we learn about the impact of environmental changes on amphibians, the better we as humans will be able to arrest their demise, and our own. Status of Conservation and Decline of Amphibians brings together the current knowledge on the status of the unique frogs of Australia, New Zealand, and the Pacific. Although geographically proximate, each region presents unique challenges and opportunities in amphibian research and conservation. This book contributes to an understanding of the current conservation status of the amphibians of each region, aims to stimulate research into halting amphibian declines, and provides a better foundation for making conservation decisions. It is an invaluable reference for environmental and governmental agencies, researchers, policy-makers involved with biodiversity conservation, and the interested public.

scholarly journals Democratizing ownership and participation in the 4th Industrial Revolution: challenges and opportunities in cellular agriculture

2021 ◽  
Author(s):  
Robert M. Chiles ◽  
Garrett Broad ◽  
Mark Gagnon ◽  
Nicole Negowetti ◽  
Leland Glenna ◽  
...  
Keyword(s):  
Business Models ◽  
Industrial Revolution ◽  
Cultured Cells ◽  
Advanced Materials ◽  
High Stakes ◽  
Digital Platforms ◽  
Challenges And Opportunities ◽  
The Status ◽  
Political Economic ◽  
Industry Sectors

AbstractThe emergence of the “4th Industrial Revolution,” i.e. the convergence of artificial intelligence, the Internet of Things, advanced materials, and bioengineering technologies, could accelerate socioeconomic insecurities and anxieties or provide beneficial alternatives to the status quo. In the post-Covid-19 era, the entities that are best positioned to capitalize on these innovations are large firms, which use digital platforms and big data to orchestrate vast ecosystems of users and extract market share across industry sectors. Nonetheless, these technologies also have the potential to democratize ownership, broaden political-economic participation, and reduce environmental harms. We articulate the potential sociotechnical pathways in this high-stakes crossroads by analyzing cellular agriculture, an exemplary 4th Industrial Revolution technology that synergizes computer science, biopharma, tissue engineering, and food science to grow cultured meat, dairy, and egg products from cultured cells and/or genetically modified yeast. Our exploration of this space involved multi-sited ethnographic research in both (a) the cellular agriculture community and (b) alternative economic organizations devoted to open source licensing, member-owned cooperatives, social financing, and platform business models. Upon discussing how these latter approaches could potentially facilitate alternative sociotechnical pathways in cellular agriculture, we reflect upon the broader implications of this work with respect to the 4th Industrial Revolution and the enduring need for public policy reform.

scholarly journals Glycosylation of matrix metalloproteases and tissue inhibitors: present state, challenges and opportunities

2016 ◽  
Vol 473 (11) ◽  
pp. 1471-1482 ◽  
Author(s):  
Lise Boon ◽  
Estefania Ugarte-Berzal ◽  
Jennifer Vandooren ◽  
Ghislain Opdenakker
Keyword(s):  
Matrix Metalloproteinases ◽  
Present State ◽  
Cellular Localization ◽  
Current Knowledge ◽  
Matrix Metalloproteases ◽  
Inhibitor Binding ◽  
Attachment Sites ◽  
Functional Aspects ◽  
Functional Implications ◽  
Challenges And Opportunities

Current knowledge about the glycosylation of matrix metalloproteinases (MMPs) and the inhibitors of metalloproteinases (TIMPs) is reviewed. Whereas structural and functional aspects of the glycobiology of many MMPs is unknown, research on MMP-9 and MMP-14 glycosylation reveals important functional implications, such as altered inhibitor binding and cellular localization. This, together with the fact that MMPs contain conserved and many potential attachment sites for N-linked and O-linked oligosaccharides, proves the need for further studies on MMP glycobiology.

The champions' mitochondria: is it genetically determined? A review on mitochondrial DNA and elite athletic performance

2011 ◽  
Vol 43 (13) ◽  
pp. 789-798 ◽  
Author(s):  
Nir Eynon ◽  
María Morán ◽  
Ruth Birk ◽  
Alejandro Lucia
Keyword(s):  
Mitochondrial Dna ◽  
Endurance Exercise ◽  
Current Knowledge ◽  
Geographic Origin ◽  
Aerobic Performance ◽  
East African ◽  
Athletic Status ◽  
The Status ◽  
Genetically Determined ◽  
Mtdna Variants

Aerobic ATP generation by the mitochondrial respiratory oxidative phosphorylation system (OXPHOS) is a vital metabolic process for endurance exercise. Notably, mitochondrial DNA (mtDNA) codifies 13 of the 83 polypeptides implied in the respiratory chain. As such, there is a strong rationale for identifying an association between mtDNA variants and “aerobic” (endurance) exercise phenotypes. The aim of this review is to summarize current knowledge on the association between mtDNA, nuclear genes involved in mitochondriogenesis, and elite endurance athletic status. Several studies in nonathletic people have demonstrated an association between certain mtDNA lineages and aerobic performance, characterized by maximal oxygen uptake (V̇o2max). Whether mtDNA haplogroups are also associated with the status of being an elite endurance athlete is more controversial, with differences between studies arising from the different ethnic backgrounds of the athletic cohorts (Caucasian of mixed geographic origin, Asiatic, or East African).

scholarly journals Challenges and Opportunities in NUT Carcinoma Research

Genes ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 235
Author(s):  
Bin Gu ◽  
Maxwell C. Hakun
Keyword(s):  
Cell Biology ◽  
Current Knowledge ◽  
Short Review ◽  
Specific Protein ◽  
Cell Of Origin ◽  
Chromosome Translocations ◽  
Very Young Children ◽  
Aggressive Cancer ◽  
Challenges And Opportunities ◽  
Nut Carcinoma

NUT carcinoma (NC) is a type of aggressive cancer driven by chromosome translocations. Fusion genes between a DNA-binding protein, such as bromodomain and extraterminal domain (BET) proteins, and the testis-specific protein NUTM1 generated by these translocations drive the formation of NC. NC can develop in very young children without significant accumulation of somatic mutations, presenting a relatively clean model to study the genetic etiology of oncogenesis. However, after 20 years of research, a few challenging questions still remain for understanding the mechanism and developing therapeutics for NC. In this short review, we first briefly summarize the current knowledge regarding the molecular mechanism and targeted therapy development of NC. We then raise three challenging questions: (1) What is the cell of origin of NC? (2) How does the germline analogous epigenetic reprogramming process driven by the BET-NUTM1 fusion proteins cause NC? and (3) How will BET-NUTM1 targeted therapies be developed? We propose that with the unprecedented technological advancements in genome editing, animal models, stem cell biology, organoids, and chemical biology, we have unique opportunities to address these challenges.

Global Regulatory Standards in Environmental and Health Disputes

2021 ◽  
Author(s):  
Caroline E. Foster
Keyword(s):  
International Law ◽  
Dispute Settlement ◽  
International Court Of Justice ◽  
Regulatory Standards ◽  
International Court ◽  
Challenges And Opportunities ◽  
The Status ◽  
Private Actors ◽  
Fragmentation Of International Law ◽  
The Relationship

Potentially global regulatory standards are emerging from the environmental and health jurisprudence of the International Court of Justice, the World Trade Organization, under the United Nations Convention on the Law of the Sea, and investor-state dispute settlement. Most prominent are the three standards of regulatory coherence, due regard for the rights of others, and due diligence in the prevention of harm. These global regulatory standards are a phenomenon of our times, representing a new contribution to the ordering of the relationship between domestic and international law, and inferring a revised conception of sovereignty in an increasingly pluralistic global legal era. However, considered with regard to jurisprudential theory on relative authority, the legitimacy of the resulting ‘standards-enriched’ international law remains open to question. Procedurally, although they are well-placed to provide valuable input, international courts and tribunals should not be the only fora in which these standards are elaborated. Substantively, challenges and opportunities lie ahead in the ongoing development of global regulatory standards. Debate over whether regulatory coherence should go beyond reasonableness and rationality requirements and require proportionality in the relationship between regulatory measures and their objectives is central. Due regard, the most novel of the emerging standards, may help protect international law’s legitimacy claims in the interim. Meanwhile, all actors should attend to the integration rather than the fragmentation of international law, and to changes in the status of private actors.

scholarly journals Rhodoliths in Brazil: Current knowledge and potential impacts of climate change

2016 ◽  
Vol 64 (spe2) ◽  
pp. 117-136 ◽  
Author(s):  
Paulo Antunes Horta ◽  
Pablo Riul ◽  
Gilberto M. Amado Filho ◽  
Carlos Frederico D. Gurgel ◽  
Flávio Berchez ◽  
...  
Keyword(s):  
Climate Change ◽  
Global Change ◽  
Ocean Acidification ◽  
Heat Waves ◽  
Current Knowledge ◽  
Coastal Pollution ◽  
Brazil Current ◽  
Run Off ◽  
Benthic Ecosystems ◽  
Impacts Of Climate Change

Abstract Rhodolith beds are important marine benthic ecosystems, representing oases of high biodiversity among sedimentary seabed environments. They are found frequently and abundantly, acting as major carbonate 'factories' and playing a key role in the biogeochemical cycling of carbonates in the South Atlantic. Rhodoliths are under threat due to global change (mainly related to ocean acidification and global warming) and local stressors, such as fishing and coastal run-off. Here, we review different aspects of the biology of these organisms, highlighting the predicted effects of global change, considering the additional impact of local stressors. Ocean acidification (OA) represents a particular threat that can reduce calcification or even promote the decalcification of these bioengineers, thus increasing the eco-physiological imbalance between calcareous and fleshy algae. OA should be considered, but this together with extreme events such as heat waves and storms, as main stressors of these ecosystems at the present time, will worsen in the future, especially if possible interactions with local stressors like coastal pollution are taken into consideration. Thus, in Brazil there is a serious need for starting monitoring programs and promote innovative experimental infrastructure in order to improve our knowledge of these rich environments, optimize management efforts and enhance the needed conservation initiatives.

scholarly journals Hearing loss and cognition: a discussion for audiologists and hearing healthcare professionals

2020 ◽  
Vol 12 (3) ◽  
pp. 72-78
Author(s):  
Douglas L Beck ◽  
Sarah Bant ◽  
Nathan A Clarke
Keyword(s):  
Hearing Loss ◽  
Cognitive Decline ◽  
Hearing Aids ◽  
British Society ◽  
Future Research ◽  
People With Dementia ◽  
Challenges And Opportunities ◽  
The Status ◽  
Impact Patient Care ◽  
The Relationship

Among researchers, clinicians and patients, there is widespread and growing interest in the relationship between hearing and cognition. The Cognition in Hearing Special Interest Group (SIG) is part of the British Society of Audiology (BSA) and is uniquely positioned to explore the relationship between hearing loss, amplification and cognitive ability and cognitive decline. The multiplicity of emerging reports concerning hearing loss and cognition is increasing rapidly. In light of this vast growth, there is a risk that clinicians may be left uncertain regarding the nature and extent of the emerging evidence linking hearing and cognition. The trickle-down corollary of such uncertainty can negatively impact patient care. Answering challenging questions and disseminating complex information about the latest evidence-based hearing science are a daily part of any clinician’s role and those in audiology services may be asked “How does my hearing loss affect my chance of getting dementia?” or “can hearing aids help people with dementia?” This discussion is therefore, based on articles and information our committee members selected to represent the status quo. The Cognition in Hearing SIG aims, through this discussion article, to provide clinicians a contemporary understanding of research on this topic. We will discuss evidence concerning hearing loss and cognition and how it relates to people living with hearing loss and cognitive decline or dementia, and we shall pose some challenges and opportunities for future research and clinical practice evidence. Therefore, to address these aims in an accessible manner for clinicians, the Cognition in Hearing SIG shall address the following broad questions: What is the relationship between hearing loss and cognition? What do we know about hearing loss and cognitive performance? Is there a link between hearing loss, cognitive decline, and dementia? Can we intervene on the relationship between hearing loss and cognition?

Social enterprise as poverty reducing strategy for women

2014 ◽  
Vol 10 (3) ◽  
pp. 176-199 ◽  
Author(s):  
Sarah Fotheringham ◽  
Chad Saunders
Keyword(s):  
Social Enterprise ◽  
Poverty Reduction ◽  
Current Knowledge ◽  
Social Enterprises ◽  
Content Type ◽  
Integrative Framework ◽  
Strategic Approach ◽  
The Status ◽  
Practical Tool ◽  
Poverty Reduction Strategy

Purpose – The purpose of this study is to investigate the potential of social enterprise as a strategy for poverty reduction for women. Design/methodology/approach – A literature synthesis on the topic was conducted and patterns, linkages and gaps were examined among key themes to identify how social enterprise can potentially serve as a poverty reduction strategy for women. Findings – The paper presents the findings in terms of specific factors contributing to women’s poverty and hypothesizes mechanisms through which social enterprises can mitigate or address these factors in practice. The paper organizes these findings in an integrative framework that highlights the need to ensure a solid policy foundation is in place before a number of key support mechanisms are enabled, which then facilitate specific types of work that can then grow in a sustainable manner. Research limitations/implications – While the mechanisms and proposed framework are based on the extant literature, additional empirical investigation is required. Practical implications – Women are disproportionately burdened by poverty and the framework presented provides a very practical tool to guide the design of new or diagnosing existing social enterprises targeting poverty reduction for women. Social implications – Without a strategic approach, the risk is either perpetuating the status quo, or worse, placing those women engaged in social enterprises in a worse financial and social position. Originality/value – There is limited research on the poverty reducing role of social enterprise for women and the proposed mechanisms and integrative framework presented provide a means of synthesizing our current knowledge while providing the basis for future investigations.

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