scholarly journals Spatial Patterns and Short-term Changes of Coral Assemblages Along a Cross-shelf Gradient in the Southwestern Lagoon of New Caledonia

Diversity ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 21 ◽  
Author(s):  
Mehdi Adjeroud ◽  
Emeline Poisson ◽  
Christophe Peignon ◽  
Lucie Penin ◽  
Mohsen Kayal
Keyword(s):  
Interannual Variation ◽  
New Caledonia ◽  
Coral Cover ◽  
Biological Processes ◽  
Spatial Structures ◽  
Short Term ◽  
Conservation Actions ◽  
History Of ◽  
Barrier Reefs ◽  
Turn Over

Coral reef assemblages generally form gradients of spatial structures which are governed by a variety of interacting physical and biological processes that vary in intensity, frequency, and spatial scale. Assessing the structure of contemporary reef assemblages may help to understand future changes and to identify appropriate conservation actions. The spatial distribution and interannual variability (from 2006 to 2008) of coral assemblages were investigated at 10 stations in the southwestern lagoon of New Caledonia, and the strength of the cross-shelf gradient was evaluated. Coral cover, generic richness, and abundance of adult and juvenile assemblages were highly variable within and among the three major reef habitats (fringing, mid-shelf, and barrier reefs). Abundance increased with distance from shore, whereas generic richness and cover were not correlated with shelf position. Assemblage composition was generally related to habitat, even though some mid-shelf and fringing reef assemblages resembled those observed on other habitats. A significant correlation between juvenile and adult distributions was recorded, suggesting that adult assemblages are partly controlled by the short-term history of recruitment patterns. The interannual variation of coral assemblages was far less pronounced, with significant changes only detected at some mid-shelf and barrier reefs, for a few genera characterised by high turn-over.

A Dynamic Systems Approach to Personality

2001 ◽  
Vol 6 (3) ◽  
pp. 172-176 ◽  
Author(s):  
Lawrence A. Pervin
Keyword(s):  
Dynamic Systems ◽  
Systems Approach ◽  
Biological Processes ◽  
Recent Advances ◽  
Dynamic View ◽  
The Future ◽  
History Of

David Magnusson has been the most articulate spokesperson for a holistic, systems approach to personality. This paper considers three concepts relevant to a dynamic systems approach to personality: dynamics, systems, and levels. Some of the history of a dynamic view is traced, leading to an emphasis on the need for stressing the interplay among goals. Concepts such as multidetermination, equipotentiality, and equifinality are shown to be important aspects of a systems approach. Finally, attention is drawn to the question of levels of description, analysis, and explanation in a theory of personality. The importance of the issue is emphasized in relation to recent advances in our understanding of biological processes. Integrating such advances into a theory of personality while avoiding the danger of reductionism is a challenge for the future.

scholarly journals Nanomedicine Reformulation of Chloroquine and Hydroxychloroquine

Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 175
Author(s):  
David M. Stevens ◽  
Rachael M. Crist ◽  
Stephan T. Stern
Keyword(s):  
Safety Evaluation ◽  
Therapeutic Index ◽  
Short Term ◽  
Tissue Concentrations ◽  
History Of ◽  
History Of Use ◽  
Novel Applications ◽  
Therapeutic Doses ◽  
Extensive Clinical Experience ◽  
Higher Doses

The chloroquine family of antimalarials has a long history of use, spanning many decades. Despite this extensive clinical experience, novel applications, including use in autoimmune disorders, infectious disease, and cancer, have only recently been identified. While short term use of chloroquine or hydroxychloroquine is safe at traditional therapeutic doses in patients without predisposing conditions, administration of higher doses and for longer durations are associated with toxicity, including retinotoxicity. Additional liabilities of these medications include pharmacokinetic profiles that require extended dosing to achieve therapeutic tissue concentrations. To improve chloroquine therapy, researchers have turned toward nanomedicine reformulation of chloroquine and hydroxychloroquine to increase exposure of target tissues relative to off-target tissues, thereby improving the therapeutic index. This review highlights these reformulation efforts to date, identifying issues in experimental designs leading to ambiguity regarding the nanoformulation improvements and lack of thorough pharmacokinetics and safety evaluation. Gaps in our current understanding of these formulations, as well as recommendations for future formulation efforts, are presented.

scholarly journals Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Nobunori Takahashi ◽  
Shuji Asai ◽  
Tomonori Kobayakawa ◽  
Atsushi Kaneko ◽  
Tatsuo Watanabe ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Practice ◽  
Disease Activity ◽  
Retention Rate ◽  
Oral Prednisone ◽  
Multivariate Logistic Regression Analysis ◽  
Jak Inhibitors ◽  
Short Term ◽  
History Of ◽  
Multicenter Registry

AbstractThis study aimed to evaluate the short-term effectiveness and safety profiles of baricitinib and explore factors associated with improved short-term effectiveness in patients with rheumatoid arthritis (RA) in clinical settings. A total of 113 consecutive RA patients who had been treated with baricitinib were registered in a Japanese multicenter registry and followed for at least 24 weeks. Mean age was 66.1 years, mean RA disease duration was 14.0 years, 71.1% had a history of use of biologics or JAK inhibitors (targeted DMARDs), and 48.3% and 40.0% were receiving concomitant methotrexate and oral prednisone, respectively. Mean DAS28-CRP significantly decreased from 3.55 at baseline to 2.32 at 24 weeks. At 24 weeks, 68.2% and 64.1% of patients achieved low disease activity (LDA) and moderate or good response, respectively. Multivariate logistic regression analysis revealed that no previous targeted DMARD use and lower DAS28-CRP score at baseline were independently associated with achievement of LDA at 24 weeks. While the effectiveness of baricitinib was similar regardless of whether patients had a history of only one or multiple targeted DMARDs use, patients with previous use of non-TNF inhibitors or JAK inhibitors showed lower rates of improvement in DAS28-CRP. The overall retention rate for baricitinib was 86.5% at 24 weeks, as estimated by Kaplan–Meier analysis. The discontinuation rate due to adverse events was 6.5% at 24 weeks. Baricitinib significantly improved RA disease activity in clinical practice. Baricitinib was significantly more effective when used as a first-line targeted DMARDs.

Do researchers impact their study populations? Assessing the effect of field procedures in a long term population monitoring of sea kraits

2012 ◽  
Vol 33 (3-4) ◽  
pp. 365-372 ◽  
Author(s):  
Thomas Fauvel ◽  
François Brischoux ◽  
Marine Jeanne Briand ◽  
Xavier Bonnet
Keyword(s):  
Body Condition ◽  
New Caledonia ◽  
Stress Hormones ◽  
Population Level ◽  
Population Monitoring ◽  
Long Term Effects ◽  
Negative Effects ◽  
Short Term ◽  
Head Morphology

Long term population monitoring is essential to ecological studies; however, field procedures may disturb individuals. Assessing this topic is important in worldwide declining taxa such as reptiles. Previous studies focussed on animal welfare issues and examined short-term effects (e.g. increase of stress hormones due to handling). Long-term effects with possible consequences at the population level remain poorly investigated. In the present study, we evaluated the effects of widely used field procedures (e.g. handling, marking, forced regurgitation) both on short-term (hormonal stress response) and on long-term (changes in body condition, survival) scales in two intensively monitored populations of sea kraits (Laticauda spp.) in New Caledonia. Focusing on the most intensively monitored sites, from 2002 to 2012, we gathered approximately 11 200 captures/recaptures on 4500 individuals. Each snake was individually marked (scale clipping + branding) and subjected to various measurements (e.g. body size, head morphology, palpation). In addition, a subsample of more than 500 snakes was forced to regurgitate their prey for dietary analyses. Handling caused a significant stress hormonal response, however we found no detrimental long-term effect on body condition. Forced regurgitation did not cause any significant effect on both body condition one year later and survival. These results suggest that the strong short-term stress provoked by field procedures did not translate into negative effects on the population. Although similar analyses are required to test the validity of our conclusions in other species, our results suggest distinguishing welfare and population issues to evaluate the potential impact of population surveys.

scholarly journals Actinomyces meyeriEmpyema: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Hae Won Jung ◽  
Chong Rae Cho ◽  
Ji Yoon Ryoo ◽  
Hyun Kyo Lee ◽  
So Young Ha ◽  
...  
Keyword(s):  
Pleural Fluid ◽  
Response To Treatment ◽  
Penicillin G ◽  
Review Of The Literature ◽  
Short Term ◽  
Oral Amoxicillin ◽  
History Of ◽  
Multiple Lung Nodules ◽  
The Right ◽  
Radiological Studies

Actinomyces meyeriis an uncommon cause of human actinomycosis. Here, we report a rare case of empyema caused byA. meyeri. A 49-year-old male presented with a history of 10 days of dyspnea and chest pain. A large amount of loculated pleural effusion was present on the right side and multiple lung nodules were documented on radiological studies. A chest tube was inserted and purulent pleural fluid was drained.A. meyeriwas isolated in anaerobic cultures of the pleural fluid. The infection was alleviated in response to treatment with intravenous penicillin G (20 million IU daily) and oral amoxicillin (500 mg every 8 hours) for 4 months, demonstrating that short-term antibiotic treatment was effective.

scholarly journals Tectonic history of northern New Caledonia Basin from deep offshore seismic reflection: Relation to late Eocene obduction in New Caledonia, southwest Pacific

Tectonics ◽  
2008 ◽  
Vol 27 (6) ◽  
pp. n/a-n/a ◽  
Author(s):  
Julien Collot ◽  
Louis Geli ◽  
Yves Lafoy ◽  
Roland Vially ◽  
Dominique Cluzel ◽  
...  
Keyword(s):  
Seismic Reflection ◽  
New Caledonia ◽  
Late Eocene ◽  
Southwest Pacific ◽  
Tectonic History ◽  
History Of

Archaeology of a Piece of Gondwanaland

2015 ◽  
Author(s):  
Christophe Sand
Keyword(s):  
Cultural Change ◽  
New Caledonia ◽  
Human Settlement ◽  
European Contact ◽  
Cultural Complex ◽  
Geological Diversity ◽  
History Of ◽  
Colonial Settlement

New Caledonia is the southern-most archipelago of Melanesia. Its unique geological diversity, as part of the old Gondwana plate, has led to specific pedological and floral environments that have, since first human settlement, influenced the ways Pacific Islanders have occupied and used the landscape. This essay presents some of the key periods of the nearly 3,000 years of pre-colonial human settlement. After having presented a short history of archaeological research in New Caledonia, the essay focuses first on the Lapita foundation, which raises questions of long-term contacts and cultural change. The second part details the unique specificities developed during the “Traditional Kanak Cultural Complex,” during the millennium predating first European contact, as well as highlighting the massive changes brought by the introduction of new diseases, in the decades before the colonial settlement era. This leads to questions about archaeological history and the role of archaeology in the present decolonizing context.

Short-Term Retinal Vessel Diameter Variability in Relation to the History of Cold Extremities

2006 ◽  
Vol 47 (9) ◽  
pp. 4026 ◽  
Author(s):  
Asan Kochkorov ◽  
Konstantin Gugleta ◽  
Claudia Zawinka ◽  
Robert Katamay ◽  
Josef Flammer ◽  
...  
Keyword(s):  
Retinal Vessel ◽  
Vessel Diameter ◽  
Short Term ◽  
Retinal Vessel Diameter ◽  
History Of ◽  
Cold Extremities

What’s Next?

2009 ◽  
Vol 217 (2) ◽  
pp. 95-102 ◽  
Author(s):  
Theo Herrmann
Keyword(s):  
Historical Development ◽  
Psychological Research ◽  
History Of Psychology ◽  
Complex Pattern ◽  
Short Term ◽  
Historical Changes ◽  
The Future ◽  
History Of

One cannot predict the future of the sciences or that of psychology. The question “What’s next?” gives reason to think about which principles to which psychology has developed. In analyzing the historical development of psychology, one should differentiate between basic psychological research, psychological technology, and the structure of institutions. Historical changes of psychology occur slowly and continuously. These continuous changes are obviously a foil for short-term changes that we can refer to as discontinuities. The complex pattern of continuities and discontinuities is based on very different conditions. External and internal causes of the changes in the history of psychology are discussed.

Community Care in Camberwell

1984 ◽  
Vol 145 (2) ◽  
pp. 178-186 ◽  
Author(s):  
Elizabeth Sturt
Keyword(s):  
Patient Care ◽  
Residential Care ◽  
Day Care ◽  
Community Care ◽  
Important Determinant ◽  
First Year ◽  
Short Term ◽  
Term Care ◽  
Residential Services ◽  
History Of

SummaryA census was taken of all patients in psychiatric hostels and homes, psychiatric day care, and short-term in-patient care who also had at least one year's history of contact with services. During the following two years, 61% of the patients stayed continuously in day or residential care, while 17% were discharged from care within the first year and made no further use of day or residential services. Two main patterns of contact were evident–repeated short-term in-patient care or longer-term care in services outside hospital. Their most important determinant was whether a viable marriage still existed for the patient.

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