scholarly journals Changes in Skin Elasticity and Firmness Caused by Cosmetic Formulas Elaborated with Essential Oils of Aristeguietia glutinosa (matico) and Ocotea quixos (ishpingo). A Statistical Analysis

Cosmetics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 95
Author(s):  
Tatiana Mosquera ◽  
Sebastián Peña ◽  
Priscila Álvarez ◽  
Paco Noriega
Keyword(s):  
Statistical Analysis ◽  
Essential Oils ◽  
Prolonged Exposure ◽  
Age Groups ◽  
Cosmetic Products ◽  
Application Time ◽  
Cosmetic Industry ◽  
Skin Photoaging ◽  
Two Age Groups

External factors such as prolonged exposure to solar radiation and environmental pollution accelerate the aging process of the skin, and this process is a challenge for pharmacological science. To counteract the effects of skin photoaging, the cosmetic industry has introduced natural topical products that have proved to be effective in reducing signs of age. In this sense, a statistical analysis was conducted on the changes in the properties of firmness and elasticity of the skin caused by cosmetic formulas (lotion and cream) elaborated with essential oils of Aristeguietia glutinosa (matico) and Ocotea quixos (ishpingo) in which the concentration of the oils in two cosmetic products (lotion and cream) varied to be tested in vivo, through the measurement of elasticity and firmness in three times T1 (0 day), T2 (28 days) and T3 (56 days), and in two age groups according to the Glogau scale (30 to 40 and 41 to 50 years). The results showed positive changes in the values of elasticity and firmness of the skin in the presentation of the lotion whose concentration was 20% Aristeguietia glutinosa (matico) and 80% Ocotea quixos (ishpingo), with a minimum application time of 28 days.

scholarly journals Changes in consumption behaviours of Polish seniors - singles in 2007 and 2016

2019 ◽  
Vol 19 (2 (50)) ◽  
pp. 196-209
Author(s):  
Teresa Słaby
Keyword(s):  
Statistical Analysis ◽  
Older People ◽  
Age Groups ◽  
Polish Population ◽  
Social Situations ◽  
Goods And Services ◽  
Single Person ◽  
Research Task ◽  
Household Budget Surveys ◽  
Two Age Groups

The increase in the share of the number of older people in the Polish population requires constant diagnosis of the degree of satisfying their needs. One of the ways of such assessment is the dynamic analysis of changes in the goods and services consumption. The author's research task was to find an answer to the question whether according to subjective opinions of seniors in 2007, there were consumption restrictions caused primarily by the deterioration of the their material situation and whether this situation deepened over the next 10 years. The aim of the article is to analyze the distribution of responses to this question in 2007 and 2016 based on the results of the GUS household budget surveys in single-person households (singles), where the situation may be particularly difficult. Two age groups were distinguished, differentiating the responses. The choice of years of observation was based on the occurrence of favourable assessments of the economic and social situations in these periods. One- and multi-dimensional tools of statistical analysis were used.

scholarly journals Essential Oils and Their Individual Components in Cosmetic Products

Cosmetics ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 114
Author(s):  
Eduardo Guzmán ◽  
Alejandro Lucia
Keyword(s):  
Essential Oils ◽  
Antioxidant Properties ◽  
Cosmetic Products ◽  
Active Ingredients ◽  
Design And Optimization ◽  
Cosmetic Industry ◽  
International Regulations ◽  
Potential Applications ◽  
The Many ◽  
Botanical Extract

The current consumer demands together with the international regulations have pushed the cosmetic industry to seek new active ingredients from natural renewable sources for manufacturing more eco-sustainability and safe products, with botanical extract being an almost unlimited source of these new actives. Essential oils (EOs) emerge as very common natural ingredients in cosmetics and toiletries as a result of both their odorous character for the design and manufacturing of fragrances and perfumes, and the many beneficial properties of their individual components (EOCs), e.g., anti-inflammatory, antimicrobial and antioxidant properties, and, nowadays, the cosmetic industry includes EOs or different mixtures of their individual components (EOCs), either as active ingredients or as preservatives, in various product ranges (e.g., moisturizers, lotions and cleanser in skin care cosmetics; conditioners, masks or antidandruff products in hair care products; lipsticks, or fragrances in perfumery). However, the unique chemical profile of each individual essential oil is associated with different benefits, and hence it is difficult to generalize their potential applications in cosmetics and toiletries, which often require the effort of formulators in seeking suitable mixtures of EOs or EOCs for obtaining specific benefits in the final products. This work presents an updated review of the available literature related to the most recent advances in the application of EOs and EOCs in the manufacturing of cosmetic products. Furthermore, some specific aspects related to the safety of EOs and EOCs in cosmetics will be discussed. It is expected that the information contained in this comprehensive review can be exploited by formulators in the design and optimization of cosmetic formulations containing botanical extracts.

scholarly journals RELAÇÃO ENTRE CAPACIDADES MOTORAS DE IDOSAS PRATICANTES DE HIDROGINÁSTICA E ALONGAMENTO

2011 ◽  
Vol 16 (esp) ◽  
Author(s):  
Marcelo Gava Pompermayer ◽  
Andréa Krüger Gonçalves
Keyword(s):  
Statistical Analysis ◽  
Older Women ◽  
Age Groups ◽  
Lower Limbs ◽  
Upper Limbs ◽  
Fitness Test ◽  
Different Types ◽  
Physical Program ◽  
Physical Aptitude ◽  
Two Age Groups

O objetivo do estudo foi verificar se há relação entre capacidades motoras de idosas submetidas a um programa físico composto por dois tipos de atividade física (hidroginástica e alongamento). A amostra foi composta por 23 indivíduos saudáveis e ativos do sexo feminino, com idades entre 60 e 80 anos. Os sujeitos foram divididos em dois grupos etários (GR1 = 60 a 69 anos, GR2 = 70 a 80). Os instrumentos foram testes físicos da bateria ‘Senior Fitness Test’ de Rikli e Jones (2008). As capacidades motoras avaliadas foram: flexibilidade de membros inferiores (FLEXMI); força de membros inferiores (FMI); flexibilidade de membros superiores (FLEXMS); força de membros superiores (FMS); agilidade/equilíbrio (AE); e resistência aeróbica (RESAER). O tratamento estatístico foi realizado através da correlação de Pearson do programa SPSS 18.0. Foram encontradas, no GR1, correlações entre: FMI e FLEXMI, FMI e AE, FMI e RESAER, FLEXMI e RESAER, AE e RESAER. No GR2, a única correlação encontrada foi entre AE e RESAER. Os componentes da aptidão física, nos idosos mais jovens, apresentaram, neste estudo, maior número de correlações, indicando que incrementos em uma capacidade motora podem gerar melhoras noutra. Estudos com diferentes atividades físicas são necessários para confirmar essas relações. palavras-chave Aptidão física. Envelhecimento. Hidroginástica. Alongamento. abstract The aim of the study was to verify if there is association between the motor capacities of older women undergoing a physical program composed of two types of activities (hydrogymnastics and stretching). The sample consisted of 23 healthy and active female, aged between 60 and 80 years. The subjects were divided into two age groups (GR1 = 60 to 69 years, GR2 = 70 to 80). The instrument was the ‘Senior Fitness Test’ of Rikli and Jones (2008). Motor capacities evaluated were: lower limbs flexibility (FLEXMI), lower limbs strength (FMI), upper limbs flexibility (FLEXMS), upper limbs strength (FMS), agility / balance (AE) and aerobic resistance (RESAER). Statistical analysis was performed using the Pearson’s Correlation of SPSS 18.0. In GR1, the correlations were found between: FMI e FLEXMI, FMI e AE, FMI e RESAER, FLEXMI e RESAER, AE e RESAER. In GR2, the only correlation was found between AE and RESAER. The components of physical aptitude, in younger elderly, presented, in this study, a higher number of correlations, indicating that increases in a component can lead to improvements in another. Studies with different types of activities are needed to confirm these relationships. keywords Physical aptitude. Aging. Hydrogymnastics. Stretching.

Pharmacology, Efficacy and Safety of a Triple-Secured Fibrinogen Concentrate in Children Less than or Equal to 12 Years with Afibrinogenaemia

2020 ◽  
Vol 120 (06) ◽  
pp. 957-967
Author(s):  
Claudia Djambas Khayat ◽  
Mohamed El Khorassani ◽  
Selin Aytaç ◽  
Annie Harroche ◽  
Amel Dahmane ◽  
...  
Keyword(s):  
Geometric Mean ◽  
Age Groups ◽  
Young Patients ◽  
Treatment Modalities ◽  
Fibrinogen Concentrate ◽  
Multicentre Phase ◽  
Post Infusion ◽  
In Vivo Recovery ◽  
Two Age Groups

Abstract Objective To date, the use of a fibrinogen concentrate (FC) administered in children with inherited fibrinogen deficiency is poorly documented. Treatment modalities may differ from those of adults. The aim of this study was to investigate the pharmacokinetics (PK), efficacy (bleeding/surgery) and safety of a triple-secured FC (FibCLOT, LFB, France) in young patients aged of 12 years or less. Methods This was a prospective, non-comparative, multicentre, phase 2–3 study. Estimated PK parameters were based on population PK modelling. Target fibrinogen levels were 1.2 and 1.0 g/L for major and minor events, respectively. In vivo recovery (IVR) was calculated at study entry to tailor the dose. Results Sixteen afibrinogenaemia patients were treated with FC: 12 included in the PK study (6 aged ≤ 6 years and 6 aged 7–12 years). IVR at 1 hour post-infusion (geometric mean [coefficient of variation]) was 1.91 [20%] mg/dL per mg/kg and results were similar between the two age groups (1.87 [14%]) and (1.96 [27%]) with no statistical differences. Estimated half-life (t 1/2) was 49.0 hours [12%] with no observed differences between groups (46.6 hours [10%] and 51.6 hours [12%]). Overall efficacy was rated as excellent/good in 96.9% of 32 bleeds and in 100% of 11 surgeries. Most of the events (39/43, 90.7%) were managed with one infusion. There was no serious adverse drug reaction. Conclusion Individually tailored dosing was efficacious in children who exhibited a lower IVR and shorter t 1/2 than those previously reported in adolescent and adult patients emphasising the importance of individualised dose optimisation.

P–620 Evaluation of pregnancy and live birth outcomes at the Hewitt Fertility Centre for three newly introduced recombinant gonadotropins when compared to human menopausal gonadotropin

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
A Fernandez-Ponce ◽  
D Yell ◽  
R Gregoire ◽  
A J Drakeley
Keyword(s):  
Statistical Analysis ◽  
Birth Outcomes ◽  
Live Birth ◽  
Birth Rate ◽  
Age Groups ◽  
Implantation Rate ◽  
Live Birth Rate ◽  
Positive Test ◽  
Human Menopausal Gonadotropin ◽  
Two Age Groups

Abstract Study question To evaluate the effectiveness of three recombinant gonadotropins against the human menopausal gonadotropin currently in use at the fertility clinic. Summary answer Human menopausal gonadotropin and Follitropin Delta had the highest pregnancy and live birth outcomes compared to Follitropin Alpha 1 and 2. What is known already Currently there is no robust evidence showing a difference in pregnancy and live birth outcomes between urinary (uFSH) and recombinant (rFSH) gonadotropins. However, there is some evidence indicating that uFSH slightly increases pregnancy outcomes in advanced maternal age (AMA). The aim of this study was to evaluate the pregnancy and live birth outcomes in two age groups (<38 years old and ≥38 years old) for three newly introduced rFSH (Follitropin Delta [FD], Follitropin Alpha 1 [FA1], Follitropin Alpha 2 [FA2]) against a human menopausal gonadotropin (hMG). Study design, size, duration Patients were randomly allocated to each gonadotropin; hMG, FD, FA1 and FA2. The following outcomes were analysed; positive test rate (PTR) (no. positive test/no. oocyte collections), clinical pregnancy rate (CPR) (no. fetal hearts/no. oocyte collections), biochemical rate (BR) (no. no clinical pregnancies/no. positive tests), implantation rate (IR) (no. sacs seen/no. embryos transferred) and live birth rate (LBR) (no. live births/no. oocyte collection) for two age groups; <38 years old (<38) and ≥38 years old (AMA). Participants/materials, setting, methods The study included 1352 patients between July 2018 and December 2019. The <38 group had 1011 patients; hMG (348), FD (38), FA1 (244), FA2 (381). The AMA group had 341 patients; hMG (141), FD (12), FA1 (87), FA2 (101). Chi-square and Kruskal-Wallis tests were used for statistical analysis and p-values of < 0.05 were considered statistically significant. Main results and the role of chance In the <38 group, hMG and FD had a significantly higher PTR compared to FA1 (32.6%, 43.6%, 22.1% respectively) (p = 0.009, p = 0.004), as well as a significantly higher CPR (26.9%, 35.9%, 17.5% respectively) (p = 0.012, p = 0.008) and LBR (21.9%, 33.3%, 13.4% respectively) (p = 0.013, p = 0.0019). Patients stimulated with FD also had a significantly higher LBR compared to FA2 (33.3%, 19.5%) (p = 0.043). No significant differences were seen in the PTR (31%) or CPR (25.1%) when FA2 was compared to hMG and FD. No significant differences were seen between the 4 gonadotropins (hMG, FD, FA1 and FA2) for IR (36.8%, 46.9%, 27.9%, 38.5% respectively) (p = 0.14) and BR (17.3%, 17.6%, 21.3%, 19% respectively) (p = 0.95) In the AMA group, hMG, FD and FA1 had a significantly higher CPR compared to FA2 (20.5%, 30%, 20%, 9.3% respectively) (p = 0.021, p = 0.048, p = 0.041). Patients stimulated with FA1 had a significantly higher PTR compared to FA2 (26.3%, 14.4% respectively) (p = 0.049). No significant differences were seen compared to hMG and FD (25%, 30% respectively) (p = 0.0504, p = 0.19). No significant differences were seen between the 4 gonadotropins (hMG, FD, FA1 and FA2) for IR (23.7%, 35.7%, 21.8%, 12.5% respectively) (p = 0.094), BR (18.2%, 0%, 23.8%, 33.3% respectively) (p = 0.51) and LBR (15.2%, 20%, 12.5%, 9.3% respectively) (p = 0.53). Limitations, reasons for caution One limitation was that the FD group was the smallest study group; hence further patients should be included to obtain more reliable results. Another limitation was that statistical analysis was not performed using outcomes per cycles started, being unable to know how many abandoned cycles there were for each gonadotropin. Wider implications of the findings: hMG and FD have had the highest pregnancy and live birth outcomes for both the <38 and AMA groups and the clinic will continue to use both gonadotropins. Parameters such as staff and patient feedback, cost implications and cost-effectiveness per live birth rate now need to be considered. Trial registration number NA

scholarly journals Hyssopus Essential Oil: An Update of Its Phytochemistry, Biological Activities, and Safety Profile

2022 ◽  
Vol 2022 ◽  
pp. 1-10
Author(s):  
Javad Sharifi-Rad ◽  
Cristina Quispe ◽  
Manoj Kumar ◽  
Muhammad Akram ◽  
Mewish Amin ◽  
...  
Keyword(s):  
Essential Oils ◽  
Safety Profile ◽  
Food Industry ◽  
Biological Activities ◽  
Herbal Remedies ◽  
Household Products ◽  
Cosmetic Industry ◽  
Loss Of Appetite

The genus Hyssopus is widespread in central Asia, East Mediterranean, and Mongolian areas. It has six main species which are used as herbal remedies, such as Hyssopus officinalis which is used as a condiment and flavoring agent in food industry. The other five species are H. ambiguus, H. cuspidatus, H. latilabiatus, H. macranthus, and H. seravschanicus. Its species are used in the treatment of various ailments such as cold, cough, loss of appetite, fungal infection, and spasmodic condition. Its constituents especially essential oils are popularly used as an additive in beverages, foods, and cosmetics. The volatile constituents are used for aroma in the food industry, cosmetic industry, and household products. The important active constituents in its essential oils are β-pinene, pinocamphone, isopinocamphone, and other terpenoids. Hyssopus genus is also bundled with other secondary metabolites including flavonoids luteolin, quercetin, apigenin, and their glucosides, as well as phenolic compounds including ferulic, p-hydroxy-benzoic acid, protocatechuic acid, chlorogenic, and caffeic acid. Combinedly, the extracts of Hyssopus are reported to have potential antiviral and antifungal activities proven using in vitro studies, whereas in vivo investigations have reported the crucial role of Hyssopus extracts in plasma membrane relaxation, cytotoxic, and sedative effects. This plant is believed to be relatively safe at levels commonly used in foods; nevertheless, more studies are needed to determine the safety profile.

scholarly journals Evaluation of metals content among different cosmetic products in the Arabian market

2016 ◽  
Vol 4 (1) ◽  
pp. 53
Author(s):  
Sahar Younes Ibrahim Md ◽  
Rania Abdel Maguid Md ◽  
Maha Khaled Al-Mazroua
Keyword(s):  
Inductively Coupled Plasma ◽  
Prolonged Exposure ◽  
Age Groups ◽  
Clinical Signs ◽  
Cosmetic Products ◽  
Market Control ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry ◽  
Permissible Levels ◽  
Arsenic Copper

<p><strong>Background:</strong> Cosmetics' use is very popular all over the world and in some parts of Arabian countries. The use of some cosmetics as Kohl is part of culture and traditions, and is used since very young ages. This makes detection of heavy metal content in cosmetics marketed in Egypt and other Arabian markets of crucial importance.</p><p><strong>Objective:</strong> To evaluate the levels of heavy metals content among different cosmetic products in the Arabian market.</p><p><strong>Methods:</strong> Different brands of; anti-freckle creams, eye shadows, eyeliners, facial powders, foundation, henna and lipsticks were purchased from open markets in Egypt and Saudi Arabia. Sample preparation and analysis was conducted, to estimate levels of twelve different metals (Pb, As, Cd, Ag, Ba, Al, Cr, Mn, Co, Ni, Cu, and Zn) using Inductively Coupled Plasma Mass Spectrometry (ICP-MS).</p><p>Results: The mean concentration of some studied metals as Aluminium, lead, arsenic, copper and nickel were higher than permissible levels for cosmetics in some of the studied samples. Para- Phenylenediamine (PPD) was detected in all the studied 7 Henna samples.</p><p><strong>Conclusion:</strong> In conclusion, cosmetic contamination with metals above permissible levels is very common in most of the products available in the developing world and Arabian markets. Physicians and users must be aware of the probable toxicity of these elements and of the clinical signs of systemic poisoning. Considering popular use of cosmetics by different age groups, the hazardous cumulative effects of prolonged exposure to low concentrations of metals like; Aluminium, lead, Arsenic, nickel and copper especially in children, cannot be ruled out. Further studies are recommended in addition, cosmetic market control and legislation procedures should be thoroughly implemented.</p>

scholarly journals Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 666
Author(s):  
Jugreet B. Sharmeen ◽  
Fawzi M. Mahomoodally ◽  
Gokhan Zengin ◽  
Filippo Maggi
Keyword(s):  
Essential Oils ◽  
Major Elements ◽  
Special Focus ◽  
Market Demand ◽  
Cosmetic Products ◽  
Tea Tree ◽  
Cosmetic Industry ◽  
Cosmetic Formulations ◽  
Fragrance Compounds ◽  
Selection Of

Fragrance is an integral part of cosmetic products and is often regarded as an overriding factor in the selection of cosmetics among consumers. Fragrances also play a considerable role in masking undesirable smells arising from fatty acids, oils and surfactants that are commonly used in cosmetic formulations. Essential oils are vital assets in the cosmetic industry, as along with imparting pleasant aromas in different products, they are able to act as preservatives and active agents and, simultaneously, offer various benefits to the skin. Moreover, the stimulating demand for natural ingredients has contributed massively to a renewed interest in cosmetic and wellness industries in plant derivatives, especially essential oils. This has led popular cosmetic companies to endorse natural fragrances and opt for minimally processed natural ingredients, given the potentially adverse health risks associated with artificial fragrance chemicals, which are major elements of cosmetics. Among the high-valued essential oils used as fragrances are citrus, lavender, eucalyptus, tea tree and other floral oils, among others, while linalool, geraniol, limonene, citronellol, and citral are much-appreciated fragrance components used in different cosmetics. Thus, this review aimed to highlight the enormous versatility of essential oils as significant sources of natural fragrances in cosmetics and cosmeceuticals. Moreover, a special focus will be laid on the different aspects related to essential oils such as their sources, market demand, chemistry, fragrance classification, aroma profile, authenticity and safety.

Concordance of Glucose-Based and of HbA1c-Based Diagnoses of Diabetes in Patients with Peripheral Artery Disease—A Comparison between Two Age Groups

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1522-P
Author(s):  
CHRISTOPH H. SAELY ◽  
ALEXANDER VONBANK ◽  
CHRISTINE HEINZLE ◽  
DANIELA ZANOLIN ◽  
BARBARA LARCHER ◽  
...  
Keyword(s):  
Peripheral Artery Disease ◽  
Age Groups ◽  
Peripheral Artery ◽  
Artery Disease ◽  
Two Age Groups

Sustainable Development of Cosmetic Products in the Frame of the Laboratory Market

2018 ◽  
Vol 7 (2) ◽  
pp. 62-66
Author(s):  
Anita Tolnay ◽  
András Koris ◽  
Robert Magda
Keyword(s):  
Sustainable Development ◽  
Special Focus ◽  
International Studies ◽  
Manufacturing Companies ◽  
Cosmetic Products ◽  
Life Cycle Assessment Methodology ◽  
Market Growth ◽  
Research Activities ◽  
Cosmetic Industry ◽  
Laboratory Market

Abstract The main objective of the current study is to highlight sustainable development from the perspective of the cosmetics industry producing ‘eco-friendly’ products. In the last decades an enhancing interest is being experienced towards sustainable development among cosmetics manufacturing companies, scientific research and development (R & D) laboratories as well as green consumers in the need for natural products safer for health and less toxic for the environment. Several international studies show that cosmetic products formulated with natural ingredients developed by cosmetic industry has a higher annual market growth than for synthetic products. R & D puts special focus on new innovative technologies in green cosmetic products to meet the frequently updated requirements of regulations in compliance with the current legislation. Scientific laboratory market has an increasing importance to evaluate natural and organic raw materials. In this work the authors attempt to focus on the growing importance of research activities to sustainable cosmetics production in life cycle assessment methodology. Naturally, the conceptual scope and extent of this study do not permit all the possible issues to be examined from every aspects due to lack of data, thus it will be endeavored to point out merely the most relevant considerations in the field of cosmetic industry.

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