scholarly journals Sunscreen Boosting Effect by Solid Lipid Nanoparticles-Loaded Fucoxanthin Formulation

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 14
Author(s):  
Yong-Jik Lee ◽  
Gae-Won Nam
Keyword(s):  
Cell Damage ◽  
Research Work ◽  
Bioactive Compound ◽  
Solid Lipid Nanoparticle ◽  
High Functioning ◽  
X Ray ◽  
Solid Lipid ◽  
Cosmetic Industry ◽  
Sunscreen Agents ◽  
Sunscreen Products

Fucoxanthin is a bioactive compound that is a kind of natural carotenoid. Fucoxanthin is known to protect against UV-B-induced cell damage in hairless mice, even though it is physiochemically unstable to heat and acid due to its polyunsaturated structure, indicating that fucoxanthin possesses a low bioavailability, and this disadvantage limits its application in the cosmetic industry. Solid lipid nanoparticle (SLN) systems are known to be suitable as carriers for sunscreen agents. In this research work, the sunscreen-boosting effect of SLN, as a deliverer of functional ingredient, especially fucoxanthin, has been developed and evaluated by comparing the sunburn protection factors (SPF) of macroemulsion (cream and lotion type) and an SLN formula containing various kinds of sunscreen agents, respectively. Several results such as stability test, particle size, DSC analysis, and X-ray analysis show that the SLN formula loading fucoxanthin has the possibility of being a stable and high-functioning ingredient delivery system. Moreover, the SLN formula has shown a higher SPF value than others, meaning that the SLN formula exhibits a good sunscreen-boosting effect. This study indicates that the use of SLN as a carrier enhanced the bioavailability of fucoxanthin and shows that SLN could be a promising carrier for the production of sunscreen products by allowing the scaling-up of production.

scholarly journals Thermal, Viscoelastic, Mechanical and Wear Behaviour of Nanoparticle Filled Polytetrafluoroethylene: A Comparison

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1940 ◽  
Author(s):  
Levente Ferenc Tóth ◽  
Patrick De Baets ◽  
Gábor Szebényi
Keyword(s):  
Room Temperature ◽  
Filler Content ◽  
Research Work ◽  
Tensile Modulus ◽  
Al2o3 Content ◽  
Wear Behaviour ◽  
X Ray ◽  
Mechanical Stirring ◽  
Wear Analysis ◽  
Sintering Method

In this research work, unfilled and mono-filled polytetrafluoroethylene (PTFE) materials were developed and characterised by physical, thermal, viscoelastic, mechanical, and wear analysis. The applied fillers were graphene, alumina (Al2O3), boehmite alumina (BA80), and hydrotalcite (MG70) in 0.25/1/4/8 and 16 wt % filler content. All samples were produced by room temperature pressing–free sintering method. All of the fillers were blended with PTFE by intensive dry mechanical stirring; the efficiency of the blending was analysed by Energy-dispersive X-ray spectroscopy (EDS) method. Compared to neat PTFE, graphene in 4/8/16 wt % improved the thermal conductivity by ~29%/~84%/~157%, respectively. All fillers increased the storage, shear and tensile modulus and decreased the ductility. PTFE with 4 wt % Al2O3 content reached the lowest wear rate; the reduction was more than two orders of magnitude compared to the neat PTFE.

Effect of Cooling and Heating Rates on Polymorphic Transformations and Gelation of Tripalmitin Solid Lipid Nanoparticle (SLN) Suspensions

2008 ◽  
Vol 3 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Tarek S. Awad ◽  
Thrandur Helgason ◽  
Kristberg Kristbergsson ◽  
Eric A. Decker ◽  
Jochen Weiss ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticle ◽  
Heating Rates ◽  
Polymorphic Transformations ◽  
Solid Lipid ◽  
Lipid Nanoparticle

Biodegradable Solid Lipid Nanoparticle Flocculates for Pulmonary Delivery of Insulin

2012 ◽  
Vol 8 (5) ◽  
pp. 834-842 ◽  
Author(s):  
Xiaoyan Yang ◽  
Yongjun Liu ◽  
Chunxi Liu ◽  
Na Zhang
Keyword(s):  
Pulmonary Delivery ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle

scholarly journals Synthesis of MFe2O4/CNS (M = Zn, Ni, Mn) Composites Derived from Rice Husk by the Hydrothermal-Microwave Method for Remediation of Paddy Fields

Processes ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1349
Author(s):  
Tutik Setianingsih ◽  
Bambang Susilo ◽  
Siti Mutrofin ◽  
Bambang Ismuyanto ◽  
Andreas Novan Endaryana ◽  
...  
Keyword(s):  
Functional Groups ◽  
Rice Husk ◽  
Research Work ◽  
Ftir Spectra ◽  
Paddy Fields ◽  
Microwave Method ◽  
Pesticide Degradation ◽  
X Ray ◽  
H2o2 Solution ◽  
Carbamate Pesticide

In this research work, MFe2O4/CNS was prepared using the hydrothermal–microwave method. The influence of cations (M) toward functional groups of composites and their performance in pesticide degradation were studied. Rice husk was pyrolyzed hydrothermally (200 °C, 6 h) and by microwave (800 W, 40 min). Each product was mixed with MCl2 (Zn, Ni, Mn), FeCl3, KOH, and water, and calcined (600 °C, 15 min) to obtain a composite. Characterization by XRD confirmed the MFe2O4/CNS structure. The FTIR spectra of the composites showed different band sharpness related to C-O and M-O. A mixture of dried paddy farm soil, composite, BPMC (buthylphenylmethyl carbamate) pesticide solution (0.25%), and H2O2 solution (0.15%) was kept under dark conditions for 48 h. The solution above the soil was filtered and measured with a UV-Vis spectrophotometer at 217 nm. Applications without the composite and composite–H2O2 were also conducted. The results reveal that dark BPMC degradation with the composite was 7.5 times larger than that without the composite, and 2.9 times larger than that without the composite–H2O2. There were no significantly different FTIR spectra of the soil, soil–BPMC, soil–BPMC-H2O2, and soil–BPMC-H2O2 composite and no significantly different X-ray diffractograms between the soil after drying and soil after application for pesticide degradation using the composite.

BIOSYNTHESIZED SILVER NANOPARTICLES USING CATHARANTHUS ROSEUS AND THEIR ANTIBACTERIAL EFFICACY IN SYNERGY WITH ANTIBIOTICS; A FUTURE ADVANCEMENT IN NANOMEDICINE

2021 ◽  
pp. 116-124
Author(s):  
MONIKA GUPTA
Keyword(s):  
Electron Microscopy ◽  
Silver Nanoparticles ◽  
Catharanthus Roseus ◽  
Leaf Extract ◽  
Research Work ◽  
Resistant Bacteria ◽  
Surface Plasmon Resonance Peak ◽  
Plasmon Resonance Peak ◽  
X Ray ◽  
Uniform Dispersion

Objective: This research work develops an approach to synthesize silver nanoparticles (AgNPs) by reduction of leaf extract of Catharanthus roseus plant. This study produces synthesized nanoparticles that have process-controlled attributes which make their antibiotic action highly efficient. These attributes include smaller size, proper morphology, uniform dispersion, metal ion content, and formation of functional groups. By optimizing the reduction process parameters, AgNPs gain the desired properties.  Methods: The biosynthesis of AgNPs process was performed using reaction of 10% (w/v) C. roseus leaf extract with AgNO3. The optimum conditions and concentration used for synthesis of nanoparticles were: 1 mM AgNO3, pH 5, and temperature 80°C with an incubation time of 72 h. All the above parameters were analyzed by ultraviolet-visible spectrophotometer with the surface plasmon resonance peak obtained at 440 nm. Results: Various characterization techniques were performed, namely, scanning electron microscopy, energy-dispersive X-ray, transmission electron microscopy, photoluminescence study, X-ray diffraction spectroscopy, Fourier transform infrared, dynamic light scattering, and atomic force microscopy. The results obtained from characterization confirmed the spherical morphology of the nanoparticles with size between 50 and 87 nm. In the current investigation, the antimicrobial activity of biosynthesized AgNPs was also determined using minimum inhibitory concentration and zone of inhibition methods against six different bacteria at different doses of AgNPs (100, 150, and 200 μg/ml) alone and also in combination with antibiotic-streptomycin. Conclusion: The results revealed that high concentration of AgNPs inhibits the bacterial growth. Furthermore, AgNPs revealed much stronger antibacterial action in synergy with streptomycin against antibiotic-resistant bacteria.

scholarly journals Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics

2016 ◽  
pp. 1019 ◽  
Author(s):  
Yi-Ping Fang ◽  
Chih-Hung Chuang ◽  
Pao-Chu Wu ◽  
Yaw-Bin Huang ◽  
Cherng-Chyi Tzeng ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle
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