scholarly journals Action Spectrum on UVA Irradiation for Formation of Persistent Pigmentation in Normal Japanese Individuals

Cosmetics ◽  
2017 ◽  
Vol 4 (4) ◽  
pp. 55 ◽  
Author(s):  
Kazuhisa Maeda
Keyword(s):  
Action Spectrum ◽  
Uva Irradiation ◽  
Normal Japanese

An Action Spectrum of the Riboflavin Photosensitized Inactivation of Lambda Phage

2004 ◽  
Author(s):  
Christopher B. Martin ◽  
Erin Wilfong ◽  
Patrick Ruane ◽  
Raymond Goodrich ◽  
Matthew Platz
Keyword(s):  
Action Spectrum ◽  
Lambda Phage ◽  
Photosensitized Inactivation

Action spectrum for cross-reactivation with various amber mutants of bacteriophage T4D

1966 ◽  
Vol 21 (2) ◽  
pp. 395-397 ◽  
Author(s):  
Amir Muhammed ◽  
Charles M. Steinberg
Keyword(s):  
Action Spectrum

scholarly journals Aerosol-based antimicrobial photoinactivation in the lungs: an action spectrum study

2021 ◽  
Author(s):  
Chiara Treghini ◽  
Alfonso Dell’Accio ◽  
Franco Fusi ◽  
Giovanni Romano
Keyword(s):  
Light Source ◽  
A Priori ◽  
Action Spectrum ◽  
Multidrug Resistant ◽  
Theoretical Modelling ◽  
Resistant Bacteria ◽  
Lung Infections ◽  
Killing Action ◽  
Definition Of

AbstractChronic lung infections are among the most diffused human infections, being often associated with multidrug-resistant bacteria. In this framework, the European project “Light4Lungs” aims at synthesizing and testing an inhalable light source to control lung infections by antimicrobial photoinactivation (aPDI), addressing endogenous photosensitizers only (porphyrins) in the representative case of S. aureus and P. aeruginosa. In the search for the best emission characteristics for the aerosolized light source, this work defines and calculates the photo-killing action spectrum for lung aPDI in the exemplary case of cystic fibrosis. This was obtained by applying a semi-theoretical modelling with Monte Carlo simulations, according to previously published methodology related to stomach infections and applied to the infected trachea, bronchi, bronchioles and alveoli. In each of these regions, the two low and high oxygen concentration cases were considered to account for the variability of in vivo conditions, together with the presence of endogenous porphyrins and other relevant absorbers/diffusers inside the illuminated biofilm/mucous layer. Furthermore, an a priori method to obtain the “best illumination wavelengths” was defined, starting from maximizing porphyrin and light absorption at any depth. The obtained action spectrum is peaked at 394 nm and mostly follows porphyrin extinction coefficient behavior. This is confirmed by the results from the best illumination wavelengths, which reinforces the robustness of our approach. These results can offer important indications for the synthesis of the aerosolized light source and definition of its most effective emission spectrum, suggesting a flexible platform to be considered in further applications.

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