scholarly journals Malignant Phyllodes Tumor of the Breast: A Practice Review

2021 ◽  
Vol 11 (2) ◽  
pp. 205-215
Author(s):  
Ângelo Bezerra de Souza Fede ◽  
Ronaldo Pereira Souza ◽  
Mauricio Doi ◽  
Marina De Brot ◽  
Cynthia Aparecida Bueno de Toledo Osorio ◽  
...  
Keyword(s):  
Therapeutic Strategy ◽  
Multidisciplinary Approach ◽  
Phyllodes Tumor ◽  
Clinical Findings ◽  
Rare Presentation ◽  
Oncologic Surgery ◽  
Malignant Phyllodes Tumor ◽  
Adjuvant Therapies ◽  
Hereditary Syndromes ◽  
Practice Review

Introduction: Phyllodes tumor (PT) of the breast, particularly malignant phyllodes tumor (mPT), is a rare fibroepithelial neoplasm. A complex diagnosis is based on pathologic, radiologic, and clinical findings, with controversies about what is the best therapeutic strategy. Objective: Our objective was to provide an overview of the clinical, pathologic, and therapeutic aspects of this rare tumor. Conclusions: mPT is a rare presentation of breast cancer and a challenge in clinical practice. A multidisciplinary approach should take into account some aspects like pathogenic mutations and hereditary syndromes. Oncologic surgery is the fundamental approach, and the use of adjuvant therapies is still controversial due to the lack of clinical trials. Treatment recommendations should be individualized according to patient risk and preferences. Prospective studies are fundamental to clarifying the best treatment for these tumors.

Pure ground glass opacity (GGO) on chest CT: a rare presentation of lung metastasis of Malignant Phyllodes Tumor

Breast Cancer ◽  
2020 ◽  
Vol 27 (6) ◽  
pp. 1187-1190
Author(s):  
Shoko Nakamura ◽  
Takeshi Goto ◽  
Satoshi Nara ◽  
Yoichiro Kawahara ◽  
Shinichi Yashiro ◽  
...  
Keyword(s):  
Lung Metastasis ◽  
Ground Glass Opacity ◽  
Phyllodes Tumor ◽  
Chest Ct ◽  
Ground Glass ◽  
Rare Presentation ◽  
Malignant Phyllodes Tumor

Gastric antral vascular ectasia in children, rare presentation

2020 ◽  
Vol 13 (11) ◽  
pp. e236896
Author(s):  
Matthew Pizzuto ◽  
Sarah Ellul ◽  
Mohamed Shoukry
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Abdominal Ultrasound ◽  
Clinical Findings ◽  
Evidence Based ◽  
Gastric Antral Vascular Ectasia ◽  
Perianal Area ◽  
Rare Presentation ◽  
Vascular Ectasia ◽  
Blood Tests ◽  
Abdominal Examination

A 14-year-old boy, a known case of perinatal hypoxic cerebral palsy, presented to paediatric emergency with acute melaena and blood staining around feeding gastrostomy site. Physical examination revealed pallor, but no signs of distress with an unremarkable abdominal examination. Routine blood tests revealed normochromic. Abdominal ultrasound scan and Meckel’s scan were unremarkable. The patient underwent examination under anaesthesia of the perianal area and joint upper and lower gastrointestinal endoscopy. Streak-like gastritis with no signs of active bleeding lesions were noted and patchy areas of colitis involving the descending and sigmoid colon and the rectum. All clinical findings and evidence-based diagnosis matched gastric antral vascular ectasia. He was successfully managed conservatively with elemental hydrolysed feeding formula.

scholarly journals Malignant Phyllodes Tumor Including Aneurysmal Bone Cyst-Like Areas in Pregnancy - a Case Report and Review of the Literature

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Canan Kelten ◽  
Ceren Boyaci ◽  
Cem Leblebici ◽  
Kemal Behzatoglu ◽  
Didem C. Trabulus ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Cyst ◽  
Clinical Breast Examination ◽  
Phyllodes Tumor ◽  
Breast Cancer Diagnosis ◽  
Left Breast ◽  
Malignant Phyllodes Tumor ◽  
Her Family ◽  
Simple Mastectomy ◽  
Clinical Breast

Background: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. Case Report: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed. However, the biopsy was diagnosed as malignant phyllodes tumor. An evaluation by ultrasonography showed a well-defined hypoechoic mass with many cystic spaces covering the entire breast tissue. Therefore, a simple mastectomy was performed. Microscopic examination revealed a high-grade malignant phyllodes tumor. Additionally, bone cyst-like areas in the form of sponge-like blood-filled non-endothelialized spaces were observed. Conclusions: Since the breasts become larger due to the physiological changes during pregnancy, any underlying breast lesions may be obscured. Therefore, clinical breast examination in the first visit of pregnancy is important.

scholarly journals Granulocyte-colony stimulating factor-producing malignant phyllodes tumor of the breast: a rare case

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kimihisa Mizoguchi ◽  
Kazuhisa Kaneshiro ◽  
Makoto Kubo ◽  
Yoshihiko Sadakari ◽  
Yoshizo Kimura ◽  
...  
Keyword(s):  
Rare Case ◽  
Phyllodes Tumor ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Malignant Phyllodes Tumor ◽  
Csf Levels ◽  
Wbc Count ◽  
Stimulating Factor

Abstract Background Granulocyte-colony stimulating factor (G-CSF)-producing tumors can cause leukocytosis despite an absence of infection. G-CSF-producing tumors have been reported in various organs such as the lung, esophagus, and stomach but rarely in the breast. We report a case of G-CSF-producing malignant phyllodes tumor of the breast. Case presentation An 84-year-old woman visited our hospital complaining of a lump in her left breast without fever and pain. Laboratory tests revealed elevated white blood cell (WBC) count and G-CSF levels. A malignant tumor of the breast was diagnosed by core needle biopsy. We performed a total mastectomy and sentinel lymph node biopsy. The tumor was identified as a G-CSF-producing malignant phyllodes tumor. Within 7 days after surgery, the patient’s WBC count and G-CSF level had decreased to normal levels. She is alive without recurrence 13 months after surgery. Conclusions We encountered a rare case of G-CSF-producing malignant phyllodes tumor of the breast. PET–CT revealed diffuse accumulation of FDG in the bone. Phyllodes tumors need to be differentiated from bone metastasis, lymphoma, and leukemia. We must be careful to not mistake this type of tumor for bone marrow metastasis.

scholarly journals Malignant phyllodes tumor of the breast with rapid progression: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Hajime Abe ◽  
Atsuko Teramoto ◽  
Yumiko Takei ◽  
Yoshihito Tanaka ◽  
Genichiro Yoneda
Keyword(s):  
Therapeutic Strategy ◽  
Muscle Flap ◽  
Skin Grafting ◽  
Phyllodes Tumor ◽  
Rapid Progression ◽  
Total Mastectomy ◽  
Latissimus Dorsi Muscle Flap ◽  
Case Presentation ◽  
Dorsi Muscle ◽  
Short Period

Abstract Background Malignant phyllodes tumors (PTs) of the breast occur infrequently and are difficult to treat with adjuvant therapy. Here, we present a case of a female patient with a huge malignant PT with rapid progression in a short period. Case presentation A 44-year-old woman presented to our hospital with a rapid growth mass in her right breast, measuring 20 cm. She was initially diagnosed as having a borderline phyllodes tumor by core needle biopsy and underwent total mastectomy and artificial dermis was grafted, 20 days later, latissimus dorsi muscle flap and free skin grafting were performed. Two courses of doxorubicin–ifosfamide therapy were administered because of recurrence, but the patient died 4 months after the mastectomy. Conclusions A standard therapeutic strategy for malignant PTs is needed in urgently to reduce the risk of tumor recurrence.

Malignant Phyllodes Tumor With Liposarcomatous Differentiation

2005 ◽  
Vol 129 (3) ◽  
pp. 421-422
Author(s):  
Phillip A. Isotalo ◽  
Ralph L. George ◽  
Ross Walker ◽  
Sandip K. SenGupta
Keyword(s):  
Phyllodes Tumor ◽  
Malignant Phyllodes Tumor

Phyllodes Tumor Metastatic to Thyroid HürthleCell Adenoma

2002 ◽  
Vol 126 (10) ◽  
pp. 1233-1236
Author(s):  
Tamar Giorgadze ◽  
Richard M. Ward ◽  
Zubair W. Baloch ◽  
Virginia A. LiVolsi
Keyword(s):  
Tumor Metastasis ◽  
Unusual Case ◽  
Cellular Proliferation ◽  
Phyllodes Tumor ◽  
Thyroid Tumor ◽  
Cell Adenoma ◽  
Malignant Phyllodes Tumor ◽  
Hürthle Cell ◽  
Thyroid Mass ◽  
Tumor To Tumor Metastasis

Abstract We present a case of a malignant phyllodes tumor metastasizing to a Hürthle cell adenoma of the thyroid. A 55-year-old woman underwent mastectomy for a malignant phyllodes tumor. Two years later, she presented with a left thyroid mass, which was a single, circumscribed, soft, deep red-brown nodular lesion with an eccentric area of firmer consistency. Histologically, the thyroid tumor was composed of 2 distinct types of cellular proliferation. Atypical spindle cells were infiltrating between the Hürthle cell cords and follicles in a fibrosarcomatous pattern. A battery of immunohistochemical stains was applied to both the thyroid and breast tumors for comparison. Based on the histologic and immunophenotypic features of the fibrosarcomatous components of both the breast and thyroid tumors, we rendered a diagnosis of cystosarcoma phyllodes metastatic to Hürthle cell adenoma. To the best of our knowledge, this unusual case is a first report of tumor-to-tumor metastasis of a sarcoma to a primary thyroid neoplasm.

scholarly journals Fulminant course in a case of malignant phyllodes tumor

2017 ◽  
Vol 92 (2) ◽  
pp. 110
Author(s):  
Young Woo Chang ◽  
Hwan Soo Kim ◽  
Deok Woo Kim ◽  
Gil Soo Son
Keyword(s):  
Phyllodes Tumor ◽  
Malignant Phyllodes Tumor
Sign in / Sign up

Export Citation Format

Share Document