scholarly journals Pediatric Spontaneous Pneumomediastinum after a Push-Up Exercise: An Uncommon Complication of a Common Exercise

Children ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. 287
Author(s):  
Chih-Yi Tsay ◽  
Yu-Long Chen ◽  
Chien-Sheng Chen ◽  
Po-Chen Lin ◽  
Meng-Yu Wu
Keyword(s):  
Early Diagnosis ◽  
Airway Obstruction ◽  
Subcutaneous Emphysema ◽  
Therapeutic Strategies ◽  
Lung Pathology ◽  
Spontaneous Pneumomediastinum ◽  
Uncommon Condition ◽  
Uncommon Complication ◽  
Push Up

Pediatric spontaneous pneumomediastinum is an uncommon condition associated with infection, trauma, or coexisting structural lung pathology. Exercise-related spontaneous subcutaneous emphysema and pneumomediastinum are rarely reported. However, severe pneumomediastinum may coexist with pneumothorax, pneumorrhachis, and subcutaneous emphysema, which can potentially lead to serious complications, including airway obstruction and pneumorrhachis. Therefore, early diagnosis and timely management are important for physicians to determine the etiology and prevent further damage. Here, we present a case of exercise-related spontaneous subcutaneous emphysema and pneumomediastinum to highlight the pathogenesis and suggest therapeutic strategies.

scholarly journals Subcutaneous emphysema: how can we prevent and treat it?

2021 ◽  
Vol 31 (3) ◽  
pp. 24-28
Author(s):  
Elisa Siqueira-Mendes ◽  
◽  
Pamella Santana-Nunes ◽  
F BritodeMelo-Silva ◽  
SC Sartoretto-Lorenzi ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Subcutaneous Emphysema ◽  
Clinical Case ◽  
Case Reports ◽  
Third Molar ◽  
Compressed Air ◽  
Local Infection ◽  
Secondary Complications ◽  
Fascial Spaces ◽  
Uncommon Complication

Subcutaneous emphysema is described as an uncommon complication resulting from the passage of compressed air to the fascial planes and is associated, in dentistry, with restorative, endodontic treatments, periodontal surgery and extractions, the latter with a higher incidence. Early diagnosis, appropriate approach and ordering of imaging tests prevent secondary complications, such as local infection and progression to deep cervical and thoracic fascial spaces. Thus, the present clinical case reports the transoperative occurrence of subcutaneous emphysema during extraction of the lower third molar, its indicated treatment and how we can avoid this type of complication

Current Therapeutic Strategies and Perspectives for Neuroprotection in Parkinson’s Disease

2020 ◽  
Vol 26 (37) ◽  
pp. 4738-4746
Author(s):  
Mohan K. Ghanta ◽  
P. Elango ◽  
Bhaskar L. V. K. S.
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Diagnosis ◽  
Neurodegenerative Disorder ◽  
Therapeutic Strategies ◽  
Neuroprotective Agents ◽  
Striatal Neurons ◽  
The Status ◽  
Advanced Stages ◽  
Dopaminergic Pathways

Parkinson’s disease is a progressive neurodegenerative disorder of dopaminergic striatal neurons in basal ganglia. Treatment of Parkinson’s disease (PD) through dopamine replacement strategies may provide improvement in early stages and this treatment response is related to dopaminergic neuronal mass which decreases in advanced stages. This treatment failure was revealed by many studies and levodopa treatment became ineffective or toxic in chronic stages of PD. Early diagnosis and neuroprotective agents may be a suitable approach for the treatment of PD. The essentials required for early diagnosis are biomarkers. Characterising the striatal neurons, understanding the status of dopaminergic pathways in different PD stages may reveal the effects of the drugs used in the treatment. This review updates on characterisation of striatal neurons, electrophysiology of dopaminergic pathways in PD, biomarkers of PD, approaches for success of neuroprotective agents in clinical trials. The literature was collected from the articles in database of PubMed, MedLine and other available literature resources.

scholarly journals Spontaneous Pneumomediastinum, Pneumothorax, Pneumopericardium and Subcutaneous Emphysema—Not So Uncommon Complications in Patients with COVID-19 Pulmonary Infection—A Series of Cases

2021 ◽  
Vol 10 (7) ◽  
pp. 1346
Author(s):  
Talida Georgiana Cut ◽  
Cristina Tudoran ◽  
Voichita Elena Lazureanu ◽  
Adelina Raluca Marinescu ◽  
Raluca Dumache ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Subcutaneous Emphysema ◽  
Diffuse Alveolar Damage ◽  
Demographic Data ◽  
Pathophysiological Mechanism ◽  
Spontaneous Pneumomediastinum ◽  
Intensive Care Stay ◽  
Laboratory Investigations ◽  
Male Patients ◽  
Pulmonary Pathology

(1) Background: Spontaneous pneumomediastinum (PM), pneumothorax (PT), and pneumopericardium (PP) were recently reported as rare complications in patients with severe COVID-19 pneumonia, and our study aims to follow the evolution of these involvements in 11 cases. The presumed pathophysiological mechanism is air leak due to extensive diffuse alveolar damage followed by alveolar rupture. (2) Methods: We followed the occurrence of PM, PN, PP, and subcutaneous emphysema (SE) in 1648 patients hospitalized during the second outbreak of COVID-19 (October 2020–January 2021) in the main hospital of infectious diseases of our county and recorded their demographic data, laboratory investigations and clinical evolution. (3) Results: Eleven patients (0.66%) developed PM, with eight of them having associated PT, one PP, and seven SE, in the absence of mechanical ventilation. Eight patients (72.72%) died and only three (27.27%) survived. All subjects were nonsmokers, without known pulmonary pathology or risk factors for such complications. (4) Conclusions: pneumomediastinum, pneumothorax, and pneumopericardium are not so uncommon complications of SARS-CoV2 pneumonia, being observed mostly in male patients with severe forms and associated with prolonged hospitalization and poor prognosis. In some cases, with mild forms and reduced pulmonary injury, the outcome is favorable, not requiring surgical procedures, mechanical ventilation, or intensive care stay.

scholarly journals An Interesting Case of Spontaneous Pneumomediastinum with Subcutaneous Emphysema following Oral Provocative Manoeuvre

2015 ◽  
Vol 7 (2) ◽  
pp. 93-96 ◽  
Author(s):  
CB Pratibha ◽  
Deepthi Satish ◽  
Suraj Gopal
Keyword(s):  
Foreign Body ◽  
Subcutaneous Emphysema ◽  
Rare Condition ◽  
Interesting Case ◽  
Valsalva Manoeuvre ◽  
Laryngeal Edema ◽  
Airway Compromise ◽  
Air Leak ◽  
Spontaneous Pneumomediastinum ◽  
Laryngeal Involvement

ABSTRACT Aim To discuss a case of spontaneous pneumomediastinum with pneumothorax with subcutaneous emphysema presenting with stridor due to laryngeal edema with relevant review of literature. Background Spontaneous pneumomediastinum is a rare condition that has been described in healthy individuals following Valsalva manoeuvre, excessive and prolonged cough or emesis. Laryngeal involvement in these cases has not been reported so far. Case description We present an interesting case of spontaneous pneumomediastinum with pneumothorax with pneumopericardium and cervicofacial emphysema with suspected ingestion of foreign body. In view of stridor due to laryngeal edema tracheostomy was done. No obvious cause for the air leak was found on further investigations. The foreign body sensation could have led to oral provocative manoeuvres by the patient causing increased intra-alveolar pressures and air leak. Conclusion Spontaneous pneumomediastinum with cervicofacial emphysema with pneumopericardium with laryngeal involvement is very rare. Tracheostomy is essential in case of airway compromise. A thorough evaluation for the underlying condition is essential to prevent further air leak. Clinical significance In a case of spontaneous pneumomediastinum with airway compromise due to involvement of the larynx, tracheostomy is essential to secure the airway and could also help in resolution of emphysema. How to cite this article Pratibha CB, Satish D, Gopal S, Balasubramanya AM. An Interesting Case of Spontaneous Pneumomediastinum with Subcutaneous Emphysema following Oral Provocative Manoeuvre. Int J Otorhinolaryngol Clin 2015;7(2):93-96.

scholarly journals Human Papilloma Virus: Current Knowledge and Focus on Oral Health

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Luca Fiorillo ◽  
Gabriele Cervino ◽  
Giovanni Surace ◽  
Rosa De Stefano ◽  
Luigi Laino ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Human Papilloma Virus ◽  
Current Knowledge ◽  
Therapeutic Strategies ◽  
Papilloma Virus ◽  
Scientific Databases ◽  
Different Types ◽  
Oral Hpv ◽  
Type Of Injury

The human papilloma virus (HPV) is responsible for different pathological manifestations in humans. This agent gives rise to lesions of different types and in different areas of the organism, including the oral cavity. The aim of this study is to show which are the main diseases for which HPV is responsible and to bring to light some of the interceptive and therapeutic strategies. The analysis was conducted by consulting the major scientific databases with the aim of obtaining information on the characteristics of oral HPV and its management; furthermore, the literature was supported by some clinical cases proposed by the authors. The role of dentistry is essential in the early diagnosis of this type of pathologies and above all in knowing how to direct patients towards a path that can lead to patient management, especially in the event that these lesions have a malignant potential. Enhancing the knowledge and role of dentistry can lead to early diagnosis of this type of injury, intercepting a pathology that could have multiorgan implications.

scholarly journals A Case Report of Acute Airway Compromise due to Subcutaneous Emphysema

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
David Olmstead ◽  
Gary Gelfand ◽  
Ian Anderson ◽  
John B. Kortbeek
Keyword(s):  
Case Report ◽  
Airway Obstruction ◽  
Subcutaneous Emphysema ◽  
Rare Complication ◽  
Traumatic Injury ◽  
Upper Airway ◽  
Acute Management ◽  
Airway Compromise ◽  
Current Management ◽  
Airway Patency

In the acute management of a trauma patient, airway patency is of utmost importance. The present case describes a male patient who presented with delayed severe upper airway obstruction secondary to massive subcutaneous emphysema following blunt traumatic injury two days previously. Airway compromise is a rarely described but serious complication of subcutaneous emphysema. Current management of subcutaneous emphysema and its association with pneumothorax is summarized. Early decompression of underlying pneumothoraces in patients with significant subcutaneous emphysema should be performed to avoid this rare complication.

scholarly journals Spontaneous pneumomediastinum and subcutaneous emphysema in a child with unknown aetiology

2019 ◽  
Vol 12 (2) ◽  
pp. e226805
Author(s):  
Anoopkishore Chidambaram ◽  
Sirisha Donekal
Keyword(s):  
Subcutaneous Emphysema ◽  
Rare Entity ◽  
X Ray ◽  
Spontaneous Pneumomediastinum ◽  
Expert Opinions ◽  
Repeat Chest ◽  
Chest X Ray ◽  
Red Flag ◽  
Surgical Emphysema ◽  
Safety Netting

Spontaneous subcutaneous emphysema and pneumomediastinum in children without any predisposing factors is a rare entity. We present a case of an adolescent boy with spontaneous pneumomediastinum. He is a 14-year-old boy brought to the hospital with an odd feeling in the neck and chest. Initial chest X-ray revealed subcutaneous emphysema and pneumomediastinum. He was further evaluated with CT thorax and abdomen with contrast which revealed extensive pneumomediastinum with associated surgical emphysema in the chest wall and neck. Expert opinions from the cardiothoracic and respiratory teams were obtained. The child was discharged with safety netting and description of red flag signs. Repeat chest X-ray in 2 weeks showed complete resolution of the pneumomediastinum and subcutaneous emphysema. We will briefly discuss about the diagnosis and treatment of spontaneous pneumomediastinum and subcutaneous emphysema.

Acute Management of Intracranial Hemorrhage in Patients Receiving Thrombolytic Therapy: Case Reports

Neurosurgery ◽  
1990 ◽  
Vol 26 (5) ◽  
pp. 867-869 ◽  
Author(s):  
Scott M. Eleff ◽  
Cecil Borel ◽  
William R. Bell ◽  
Donlin M. Long
Keyword(s):  
Early Diagnosis ◽  
Thrombolytic Therapy ◽  
Intracranial Hemorrhage ◽  
Antithrombotic Therapy ◽  
Perioperative Management ◽  
Case Reports ◽  
Acute Management ◽  
Anticoagulant Treatment ◽  
Life Threatening ◽  
Uncommon Complication

Abstract Intracranial hemorrhage is an uncommon complication of antithrombotic therapy. We present two patients who suffered life-threatening intracranial bleeding as a complication of thrombolytic/anticoagulant treatment. Early diagnosis and treatment appear to be crucial factors for survival. We suggest an approach to perioperative management for intracranial hemorrhage resulting from antithrombotic therapy.

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