scholarly journals Human Papilloma Virus-Associated Cervical Cancer and Health Disparities

Cells ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 622 ◽  
Author(s):  
Patti Olusola ◽  
Hirendra Nath Banerjee ◽  
Julie V. Philley ◽  
Santanu Dasgupta

Cervical cancer develops through persistent infection with high-risk human papilloma virus (hrHPV) and is a leading cause of death among women worldwide and in the United States. Periodic surveillance through hrHPV and Pap smear-based testing has remarkably reduced cervical cancer incidence worldwide and in the USA. However, considerable discordance in the occurrence and outcome of cervical cancer in various populations exists. Lack of adequate health insurance appears to act as a major socioeconomic burden for obtaining cervical cancer preventive screening in a timely manner, which results in disparate cervical cancer incidence. On the other hand, cervical cancer is aggressive and often detected in advanced stages, including African American and Hispanic/Latina women. In this context, our knowledge of the underlying molecular mechanism and genetic basis behind the disparate cervical cancer outcome is limited. In this review, we shed light on our current understanding and knowledge of racially disparate outcomes in cervical cancer.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 5605-5605
Author(s):  
Marie-Anne Froment ◽  
Audrey Roux ◽  
Mindy C. DeRouen ◽  
Scarlett Lin Gomez ◽  
Elizabeth A. Kidd

5605 Background: The incidence of cervical cancer in the United States has declined since the introduction of the pap smear. However, differences exist based on ethnicity and socioeconomic status (SES).This study aimed to evaluate the impact of nativity, neighborhood SES and enclave (degree of ethnic isolation) on the incidence of cervical cancer in California. Methods: Using data from the California Cancer Registry, comprising three of the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) program registries, information on all primary invasive cervical cancer diagnosed in California from January 1, 1990, through December 31, 2004 was obtained. We analyzed the influence of enclave, SES, and nativity on cervical cancer incidence. Results: Among the 22,189 invasive cervical cancer cases diagnosed between 1990 and 2004, 50% were non-Hispanic white (NHW), 39% Hispanic and 11% Asian women. Seventy percent (70%) of the invasive cervical cancer cases were squamous cell carcinoma (SCC), 19% were adenocarcinoma and 11% other histologies. Approximately half (51%) of patients presented with localized disease, 33% regional disease, 10% distant disease and 6% unknown. By ethnic group, US born women showed lower rates of SCC compared to foreign-born women. Seventy-six percent (76%) of invasive cervical cases were observed in high enclave neighborhoods, and seventy percent (70%) were noted in low SES neighborhoods. Hispanics living in low SES and high enclave had 12.7 times (95% CI; 11.2-14.3) higher rate of cervical cancer than those living in high SES, low enclave neighborhoods. For Asian women incidence rates were 6 times (95% CI; 4.9-7.5) higher in the low SES, high enclave neighborhoods compared to those living in high SES, low enclave neighborhoods. Conclusions: More efforts should be done to reach out to and increase pap smear screening for women living in high enclave neighborhoods to help decrease the incidence of invasive cervical cancer cases in these groups of women.


2019 ◽  
Vol 147 (3) ◽  
pp. 887-896
Author(s):  
Rebecca Landy ◽  
Peter D. Sasieni ◽  
Christopher Mathews ◽  
Charles L. Wiggins ◽  
Michael Robertson ◽  
...  

Scientifica ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Olusola Anuoluwapo Akanbi ◽  
Abiodun Iyanda ◽  
Folakemi Osundare ◽  
Oluyinka Oladele Opaleye

Background. Cervical cancer caused by human papilloma virus (HPV) though preventable has claimed the lives of many women worldwide. This study was embarked upon to evaluate the general knowledge and perceptions of Nigerian women on HPV, cervical cancer, and HPV vaccine.Methods. Structured questionnaires were administered to a cross section of 737 women randomly selected from the general population in two southwestern States of Nigeria. Statistical analysis was done using SPSS computer software version 16. APvalue >0.05 was considered statistically significant.Results. One hundred and seventy-six (23.9%) of the respondents had knowledge of HPV; 474 (64.3%) are aware of cervical cancer but only 136 (18.5%) know that HPV causes cervical cancer. 200 (27.1%) are aware that there is an HPV vaccine while 300 (40.7%) had knowledge of Pap smear test. Two hundred and sixty (35.3%) of the respondents know that early detection of HPV can prevent cervical cancer and in spite of this, only 110 (14.9%) have taken the Pap smear test before while 151 (20.5%) are not willing to go for the test at all.Conclusions. There is therefore the need to create proper awareness on the HPV and its possible consequence of cervical carcinoma.


2002 ◽  
Vol 6 (22) ◽  
Author(s):  
◽  

Following two conferences which took place in the United States (US) last year, the American Medical Association has recently published two consensus statements concerning screening for and management of cervical cancer (1-3). It is recommended that human papilloma virus (HPV) testing become an integral part of both screening and clinical management of cervical cytological abnormalities.


2021 ◽  
Vol 14 (1) ◽  
pp. 63-67
Author(s):  
Nur Zuwariah ◽  
Rizki Amalia ◽  
Syafaatul Ainiyah

One of the most dangerous diseases for Indonesian women is cervical cancer. Hormonal contraceptive use is one of the risk factors for cervical cancer, especially in prolonged use for more than five years. This study evaluates the correlation between hormonal contraceptive use with cervical cancer incidence in Surabaya Wisnuwardhana Cancer Foundation. In this research, the authors used the analytical design with the cross-sectional approach. There were 30 respondents selected with the purposive sampling technique. The independent variable was hormonal contraceptive use, and the dependent variable was cervical cancer incidence. The instruments utilized questionnaires and medical records. Data analysis applied the Rank-spearman test with the significance level of α = 0.05. The results showed that most of the respondents (63,3%) used hormonal contraception. Almost half of them (46.7%) are categorized in class 2 of pap smear classification (mild infection). Hormonal contraceptive use correlated with cervical cancer incidence (p=0.005). The prolonged hormonal contraceptive use, the greater cervical cancer incidence in women.  


Author(s):  
Nicholas Salas

As of 2014, Texas has the 6th highest incidence rate and the 5th highest mortality rate of cervical cancer in the nation. In addition, Texas ranks 3rd to last in the United States in human papilloma (HPV) vaccinations, which helps prevent one of the leading causes of cervical cancer. Cervical cancer incidence rates in Texas remain high, despite it becoming one the most successfully preventable treatable cancers in the United States due to a combination of screenings and HPV vaccinations. Furthermore, spatial distribution of cervical cancer is unknown among Texas counties. This study will follow the political ecology model to elaborate on the political, historical, social, and economic factors that may explain why HPV vaccinations are low and the incidence rate remains high despite the interventions available to people in Texas. This study will examine the geography of cervical cancer in Texas counties from 1995 - 2015 as well as its relationship with religious adherence, socioeconomic status, race/ethnicity, and uninsured rates. I will use a bivariate correlation to relate these factors with cancer incidence rates and ArcMap to create maps to illustrate the spatial distribution of these diseases. The data will be obtained from the Texas Cancer Registry, Texas County Health Rankings 2018, and the Association of Religion Data (CDC) Archives (ARDA). I expect that cervical cancer rates will decline after the introduction of the HPV vaccine in 2007, but areas with higher religious adherence will have higher rates of cervical cancer. In addition, I expect that uninsured rates, race/ethnicity, and socioeconomic factors could possibly impact cervical cancer incidence rates.


2017 ◽  
Vol 14 (1) ◽  
pp. 403-410
Author(s):  
P. S Ramapraba ◽  
M. P Chitra ◽  
M PremKumar

Cervical cancer is the second most leading cancer among women. Source of cervical cancer is Human Papilloma Virus (HPV). Tests to confirm a diagnosis of cervical cancer are colposcopy and cervical biopsy (pap smear). This paper includes the usage of colposcopy images and tests to find where cancer cells are on the surface of the cervix. Contourlet transform (CT) is proposed to extract the features of the colposcopy images and then for classification of Aceto white Region (Abnormal) and Non Aceto white Region (Normal), K-Nearest Neighbourhood (KNN) classifier is used. In the existing system, wavelet transforms are used to extract the features in which minimum quantity of information and features are obtained (Only 3 directions are focused). In CT, for higher resolution, additional directional is employed. The greater performance is achieved by extracting and choosing the simplest features from contourlet coefficients of the colposcopy images and these outputs are fed into the KNN classifier for classification.


2012 ◽  
Vol 127 (3) ◽  
pp. 611-615 ◽  
Author(s):  
Edgar P. Simard ◽  
Deepa Naishadham ◽  
Debbie Saslow ◽  
Ahmedin Jemal

Cancer ◽  
2008 ◽  
Vol 113 (S10) ◽  
pp. 2964-2973 ◽  
Author(s):  
Steven S. Coughlin ◽  
Thomas B. Richards ◽  
Kiumarss Nasseri ◽  
Nancy S. Weiss ◽  
Charles L. Wiggins ◽  
...  

2007 ◽  
Vol 110 (3) ◽  
pp. 681-686 ◽  
Author(s):  
Vicki B. Benard ◽  
Steven S. Coughlin ◽  
Trevor Thompson ◽  
Lisa C. Richardson

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