scholarly journals EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

Cancers ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 109 ◽  
Author(s):  
Joanna Wilson ◽  
Evelyne Manet ◽  
Henri Gruffat ◽  
Pierre Busson ◽  
Marc Blondel ◽  
...  
Keyword(s):  
Immune Evasion ◽  
Epstein Barr Virus ◽  
Therapeutic Strategies ◽  
Barr Virus ◽  
Oncogenic Activity ◽  
Epstein Barr ◽  
Novel Therapeutic Strategies ◽  
Novel Therapeutic

scholarly journals Novel cationic bis(acylhydrazones) as modulators of Epstein–Barr virus immune evasion acting through disruption of interaction between nucleolin and G-quadruplexes of EBNA1 mRNA

2019 ◽  
Vol 178 ◽  
pp. 13-29 ◽  
Author(s):  
Oksana Reznichenko ◽  
Alicia Quillévéré ◽  
Rodrigo Prado Martins ◽  
Nadège Loaëc ◽  
Hang Kang ◽  
...  
Keyword(s):  
Immune Evasion ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

Prophylactic and therapeutic strategies for Epstein–Barr virus-associated diseases: emerging strategies for clinical development

2019 ◽  
Vol 18 (5) ◽  
pp. 457-474 ◽  
Author(s):  
Vijayendra Dasari ◽  
Debottam Sinha ◽  
Michelle A. Neller ◽  
Corey Smith ◽  
Rajiv Khanna
Keyword(s):  
Epstein Barr Virus ◽  
Therapeutic Strategies ◽  
Clinical Development ◽  
Barr Virus ◽  
Associated Diseases ◽  
Epstein Barr

scholarly journals Exosomal Communication Goes Viral

2015 ◽  
Vol 89 (10) ◽  
pp. 5200-5203 ◽  
Author(s):  
David G. Meckes
Keyword(s):  
Immune Evasion ◽  
Intercellular Communication ◽  
Epstein Barr Virus ◽  
Current Knowledge ◽  
Virus Spread ◽  
Barr Virus ◽  
Tumor Viruses ◽  
Communication Events ◽  
Epstein Barr

Exosomes are small vesicles secreted from cells that participate in intercellular communication events. Accumulating evidence demonstrates that host exosome pathways are hijacked by viruses and that virally modified exosomes contribute to virus spread and immune evasion. In the case of tumor viruses, recent findings suggest that alterations in normal exosome biology may promote the development and progression of cancer. These studies will be discussed in the context of our current knowledge of Epstein-Barr virus (EBV)-modified exosomes.

scholarly journals Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
María José Lista ◽  
Rodrigo Prado Martins ◽  
Olivier Billant ◽  
Marie-Astrid Contesse ◽  
Sarah Findakly ◽  
...  
Keyword(s):  
Immune Evasion ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals A yeast model for the mechanism of the Epstein‐Barr virus immune evasion identifies a new therapeutic target to interfere with the virus stealthiness

2017 ◽  
Vol 4 (9) ◽  
pp. 305-307 ◽  
Author(s):  
María José Lista ◽  
Rodrigo Prado Martins ◽  
Gaelle Angrand ◽  
Alicia Quillévéré ◽  
Chrysoula Daskalogianni ◽  
...  
Keyword(s):  
Immune Evasion ◽  
Therapeutic Target ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
Yeast Model

What is after cytokine-blocking therapy, a novel therapeutic target — Synovial Epstein-Barr virus for rheumatoid arthritis

2007 ◽  
Vol 6 (3) ◽  
pp. 126-130 ◽  
Author(s):  
Shigemasa Sawada ◽  
Masami Takei ◽  
Hirotake Inomata ◽  
Takamasa Nozaki ◽  
Hidetaka Shiraiwa
Keyword(s):  
Rheumatoid Arthritis ◽  
Therapeutic Target ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
Novel Therapeutic

scholarly journals The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation

2009 ◽  
Vol 5 (1) ◽  
pp. e1000255 ◽  
Author(s):  
Jianmin Zuo ◽  
Andrew Currin ◽  
Bryan D. Griffin ◽  
Claire Shannon-Lowe ◽  
Wendy A. Thomas ◽  
...  
Keyword(s):  
G Protein ◽  
Mhc Class I ◽  
Immune Evasion ◽  
Epstein Barr Virus ◽  
Class I ◽  
G Protein Coupled Receptor ◽  
Barr Virus ◽  
Epstein Barr ◽  
G Protein Coupled ◽  
Mhc Class I Molecules

scholarly journals Cooperation between Epstein-Barr Virus Immune Evasion Proteins Spreads Protection from CD8+ T Cell Recognition across All Three Phases of the Lytic Cycle

2014 ◽  
Vol 10 (8) ◽  
pp. e1004322 ◽  
Author(s):  
Laura L. Quinn ◽  
Jianmin Zuo ◽  
Rachel J. M. Abbott ◽  
Claire Shannon-Lowe ◽  
Rosemary J. Tierney ◽  
...  
Keyword(s):  
T Cell ◽  
Immune Evasion ◽  
Epstein Barr Virus ◽  
Cd8 T Cell ◽  
Lytic Cycle ◽  
Cell Recognition ◽  
T Cell Recognition ◽  
Barr Virus ◽  
Epstein Barr ◽  
Three Phases
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