scholarly journals Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics

Biosensors ◽  
2015 ◽  
Vol 5 (3) ◽  
pp. 577-601 ◽  
Author(s):  
Shikha Sharma ◽  
Julia Zapatero-Rodríguez ◽  
Pedro Estrela ◽  
Richard O'Kennedy
Keyword(s):  
Present Status ◽  
Point Of Care ◽  
Low Resource Settings ◽  
Future Role ◽  
Low Resource ◽  
Point Of Care Diagnostics

scholarly journals Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

Lab on a Chip ◽  
2017 ◽  
Vol 17 (20) ◽  
pp. 3351-3387 ◽  
Author(s):  
Catherine E. Majors ◽  
Chelsey A. Smith ◽  
Mary E. Natoli ◽  
Kathryn A. Kundrod ◽  
Rebecca Richards-Kortum
Keyword(s):  
Neonatal Mortality ◽  
Point Of Care ◽  
Neonatal Health ◽  
Low Resource Settings ◽  
Low Resource ◽  
Point Of Care Diagnostics ◽  
Maternal And Neonatal Health ◽  
Diagnostic Technologies

We present diagnostic technologies available to detect the leading causes of maternal and neonatal mortality, highlighting key gaps in development.

Use of Intrapartum Ultrasound in Low-Resource Settings: The Role of Ultrasound Triaging

2021 ◽  
pp. 445-452
Author(s):  
Yaw A. Wiafe ◽  
Alexander T. Odoi ◽  
Edward T. Dassah ◽  
Ruth E. Zielinski
Keyword(s):  
Low Resource Settings ◽  
Low Resource

scholarly journals Detecting tuberculosis: rapid tools but slow progress

2019 ◽  
Vol 9 (3) ◽  
pp. 80-83
Author(s):  
K. England ◽  
T. Masini ◽  
E. Fajardo
Keyword(s):  
Point Of Care ◽  
Scale Up ◽  
Critical Issue ◽  
World Health ◽  
High Turnover ◽  
Low Resource Settings ◽  
Laboratory Staff ◽  
Low Resource ◽  
Point Of Care Test ◽  
Health Organization

The World Health Organization (WHO) currently recommends Xpert® MTB/RIF as the initial test for all people with presumptive tuberculosis (TB). A number of challenges have been reported, however, in using this technology, particularly in low-resource settings. Here we examine these challenges, and provide our perspective of the barriers to Xpert scale-up as assessed through a survey in 16 TB burden countries in which the Médecins Sans Frontières is present. We observed that the key barriers to scale-up include a lack of policy adoption and implementation of WHO recommendations for the use of Xpert, resulting from high costs, poor sensitisation of clinical staff and a high turnover of trained laboratory staff; insufficient service and maintenance provision provided by the manufacturer; and inadequate resources for sustainability and expansion. Funding is a critical issue as countries begin to transition out of support from the Global Fund. While it is clear that there is still an urgent need for research into and development of a rapid, affordable point-of-care test for TB that is truly adapted for use in low-resource settings, countries in the meantime need to develop functional and sustainable Xpert networks in order to close the existing diagnostic gap.

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